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Open Surgical Insertion of Tenkchoff Straight Catheter Without Guide Wire

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Chinese Medical Sciences Journal 2013年第2期28卷 117-121页

作者： shi-feng yang Wu-jun Xue Ai-ping Yin Li-yi Xie Wan-hong Lu Department of Nephrology First Affiliated Hospital of Medical SchoolXi'an Jiaotong University

Objective To compare the clinical outcomes of open surgical peritoneal dialysis catheter （PDC） insertion with guide wire and the outcomes of PDC insertion without guide wire. Methods Data of the patients receiving open surgical Tenkchoff straight catheter insertion in our department from January 2005 to January 2011 were retrospectively analyzed. The 117 patients in whom PDC insertion was conducted with the guidance of guide wire were enrolled into group A, and the 121 cases receiving PDC insertion without guide wire were enrolled into group B. The incidences of post-operative complications （catheter obstruction, catheter displacement, bloody dialysate, and dialysate leakage）, catheter survival, and patient survival rates were compared between the 2 groups. Results The baseline characteristics （gender, age, body mass index, prothrombin time, activated partial thromboplastin time, platelet count, serum creatinine, follow-up time, primary diseases, and outcomes） of the 2 groups were comparable （all P〉0.05）. In post-operative complications, only the incidence of early bloody dialysate showed significant difference, being 16.2% in group A and 7.4% in group B （P=0.04）. Catheter and patient survival rates were not significantly different between the two groups. Overweight patients showed a higher incidence of catheter obstruction compared with normal weight patients [16.0% （4/25） vs. 3.3% （7/213）, P=0.02], but no differences in post-operative between the 2 groups. complications were found among overweight patients Conclusions Open surgical Tenkchoff straight catheter insertion without guide wire does not lead to higher risk of post-operative complications and catheter removal. It may be an alternative option when guide wire is not available.

关键词： peritoneal dialysis catheters surgery guide wire

Neutrophil extracellular traps participate in the development of cancer-associated thrombosis in patients with gastric cancer

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World Journal of Gastroenterology 2022年第26期28卷 3132-3149页

作者： Jia-Cheng Li Xiao-Ming Zou shi-feng yang Jia-Qi Jin Lei Zhu Chang-Jian Li Hao yang An-Ge Zhang Tian-Qi Zhao Chong-Yan Chen Department of Gastrointestinal Surgery The Second Affiliated Hospital of Harbin Medical UniversityHarbin 150001Heilongjiang ProvinceChina The Key Laboratory of Myocardial Ischemia Harbin Medical UniversityHarbin 150001Heilongjiang ProvinceChina Department of Neurosurgery The Second Affiliated Hospital of Harbin Medical UniversityHarbin 150001Heilongjiang ProvinceChina

BACKGROUND The development of venous thromboembolism(VTE) is associated with high mortality among gastric cancer(GC) patients. Neutrophil extracellular traps(NETs) have been reported to correlate with the prothrombotic state in some diseases, but are rarely reported in GC *** To investigate the effect of NETs on the development of cancer-associated thrombosis in GC *** The levels of NETs in blood and tissue samples of patients were analyzed by ELISA, flow cytometry, and immunofluorescence staining. NET generation and hypercoagulation of platelets and endothelial cells(ECs) in vitro were observed by immunofluorescence staining. NET procoagulant activity(PCA) was determined by fibrin formation and thrombin–antithrombin complex(TAT) *** in vivo was measured in a murine model induced by flow stenosis in the inferior vena cava(IVC).RESULTS NETs were likely to form in blood and tissue samples of GC patients compared with healthy individuals. In vitro studies showed that GC cells and their conditioned medium, but not gastric mucosal epithelial cells, stimulated NET release from neutrophils. In addition, NETs induced a hypercoagulable state of platelets by upregulating the expression of phosphatidylserine and Pselectin on the cells. Furthermore, NETs stimulated the adhesion of normal platelets on glass surfaces. Similarly, NETs triggered the conversion of ECs to hypercoagulable phenotypes by downregulating the expression of their intercellular tight junctions but upregulating that of tissue factor. Treatment of normal platelets or ECs with NETs augmented the level of plasma fibrin formation and the TAT complex. In the models of IVC stenosis, tumor-bearing mice showed a stronger ability to form thrombi, and NETs abundantly accumulated in the thrombi of tumorbearing mice compared with control mice. Notably, the combination of deoxyribonuclease I,activated protein C, and sivelestat markedly abolished the PCA of *** GC-induced NET

关键词： Neutrophil extracellular traps Gastric cancer Platelet Endothelial cells Venous thromboembolism

One Way to Eliminate Corruption-Educating People——Brief Introduction on Bid

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西昌农业高等专科学校学报 2001年第3期15卷 62-64页

作者： Qiu shi-feng yang Ru-ping (Xichang Agricultural College,Xichang,Sichuan,615013)

This article,according to the author's working experience in a hydropower project,briefly introduces some basic knowledge about bidding process and sample contract *** is aiming at giving a common knowledge to the students who will be involved in work relating to bid after their graduation in the *** is hoped that this kind of knowledge can help people properly use funds for a project and thus corruption can be minimized.

关键词：工程投标承包合同贪污防止措施资金管理资金使用

One Way to Eliminate Corruption-Educating People——Brief Introduction on Bid

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西昌学院学报(自然科学版) 2001年第3期 62-64页

作者： Qiu shi-feng yang Ru-ping (Xichang Agricultural College,Xichang,Sichuan,615013)

This article,according to the author’s working experience in a hydropewer project,briefly introducessome basic knowledge about bidding process and sample contract *** is aiming at giving a commonknowledge to the students who will be involved in work relating to bid after their graduation in the *** ishoped that this kind of knowledge can help people properly use funds for a project and thus corruption can beminimized.

关键词： Bid Contract document Basic Knowledge Competitive Corruption

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用于等离子体诊断的新型X射线谱仪

光电子．激光 2017年第3期28卷 238-242页

作者：施军刘锋杨祖华钱凤曹磊锋重庆大学光电技术及系统教育部重点实验室重庆400044 中国工程物理研究院激光聚变研究中心四川绵阳621900

为了诊断热核聚变等离子体状态,研制了用于热斑区等离子体诊断用的新型X射线谱仪,能够同时探测X射线光谱与聚爆靶图像信息。光谱检测功能由4块椭圆晶体分析器实现,分别覆盖2~20keV能带范围不同能带的X射;图像检测功能由分幅相机匹配小... 详细信息

为了诊断热核聚变等离子体状态,研制了用于热斑区等离子体诊断用的新型X射线谱仪,能够同时探测X射线光谱与聚爆靶图像信息。光谱检测功能由4块椭圆晶体分析器实现,分别覆盖2~20keV能带范围不同能带的X射;图像检测功能由分幅相机匹配小孔阵列成像完成,理想状态能够得到20幅不同时间的聚爆靶图像。在中物院"神光-Ⅱ"升级装置上进行了打靶实验,获取了X射线光谱与聚爆靶图像信号。分析了光谱及图像信息,并针对光谱仪漏光问题改进了谱仪结构。在神光-Ⅲ原型装置上进行了验证实验,获得比较理想的图像信号,信噪比(SNR)数据达到30。

关键词：等离子体光谱仪椭圆晶体 X射线光谱成像

Elliptical Splats Based Isosurface Visualization for Volume Data

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Journal of Shanghai Jiaotong university(Science) 2008年第5期13卷 533-537页

作者：秦红星石峰郭律杨杰 Institute of Image Processing & Pattern Recognition Shanghai Jiaotong University

Elliptical splats are used to represent and render the isosurface of volume data. The method consists of two steps. The first step is to extract points on the isosurface by looking up the case table. In the second step, properties of splats are computed based on local geometry. Rendering is achieved using surface splatting algorithm. The obtained results show that the extraction time of isosurfaces can be reduced by a factor of three. So our approach is more appropriate for interactive visualization of large medical data than the classical marching cubes (MC) technique.

关键词： volume visualization elliptical splats isosurface extraction differential geometry

Complete response of gallbladder cancer treated with gemcitabine and cisplatin chemotherapy combined with durvalumab:A case report and review of literature

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 226-232页

作者： Kai Chen Xu feng Yuan shi Xin-Lin Li Zheng-Rong shi Xiang Lan Department of Hepatobiliary Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND Gallbladder cancer(GBC)is the most common and aggressive subtype of biliary tract cancer(BTC)and has a poor prognosis.A newly developed regimen of gemcitabine,cisplatin,and durvalumab shows promise for the treatment of advanced ***,the efficacy of this treatment for GBC remains *** SUMMARY In this report,we present a case in which the triple-drug regimen exhibited marked effectiveness in treating locally advanced GBC,thus leading to a long-term survival benefit.A 68-year-old man was diagnosed with locally advanced GBC,which rendered him ineligible for curative *** three cycles of therapy,a partial response was *** one year of combined therapy,a clinical complete response was successfully *** maintenance therapy with durvalumab monotherapy resulted in a disease-free survival of 9 months for the *** patient experienced tolerable toxicities of reversible grade 2 nausea and *** adverse events were observed in the patient throughout the entirety of the *** The combination of gemcitabine and cisplatin chemotherapy with durvalumab was proven to be an effective treatment approach for advanced GBC,with manageable adverse *** research is warranted to substantiate the effectiveness of the combined regimen in the context of GBC.

关键词： Gallbladder cancer Chemotherapy Immunotherapy Durvalumab Complete response Case report

Transarterial chemoembolization combined with lenvatinib and sintilimab vs lenvatinib alone in intermediate-advanced hepatocellular carcinoma

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 52-61页

作者： Fei-Da Wu Hai-feng Zhou Wei yang Di Zhu Bi-Fei Wu Hai-Bin shi Sheng Liu Wei-Zhong Zhou Department of Interventional Radiology The First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029Jiangsu ProvinceChina

BACKGROUND Hepatocellular carcinoma(HCC)is the most common form of liver cancer that has limited treatment options and a poor *** chemoembolization(TACE)is the first-line treatment for intermediate-stage HCC but can induce tumour hypoxia,thereby promoting *** studies suggested that combining TACE with anti-angiogenic therapies and immunotherapy might im-prove ***,a tyrosine kinase inhibitor,has demonstrated superior outcomes compared to sorafenib,while immune checkpoint inhibitors such as sintilimab show potential when combined with ***,the efficacy and safety of TACE combined with lenvatinib and sintilimab(TACE+SL)compared to TACE with lenvatinib alone(TACE+L)in patients with intermediate-ad-vanced HCC has not yet been *** To evaluate the efficacy and safety of TACE+SL therapy in comparison to TACE+L therapy in patients with intermediate-advanced *** A retrospective analysis was performed on patients with intermediate-advanced HCC who received TACE plus lenvatinib with or without sintilimab between September 2019 and September *** characteristics were compared,and propensity score matching was *** survival(OS),progression-free survival(PFS),and objective response rate(ORR)were evaluated between the two groups,and adverse events were *** The study included 57 patients,with 30 in the TACE+SL group and 27 in the TACE+L *** TACE+SL group demonstrated significantly improved median PFS and OS compared to the TACE+L group(PFS:14.1 months vs 9.6 months,P=0.016;OS:22.4 months vs 14.1 months,P=0.039),along with a higher ORR(70.0%vs 55.6%).After propensity score matching,30 patients were included,with the TACE+SL group again showing longer median PFS and a trend toward improved OS(PFS:14.6 months vs 9.2 months,P=0.012;OS:23.9 months vs 16.3 months,P=0.063),and a higher ORR(73.3%vs 53.3%).No severe adverse events were *** TACE+SL demonstrat

关键词： Hepatocellular carcinoma Transarterial chemoembolization Sintilimab Lenvatinib Immunotherapy Programmed cell death 1 Prognosis

茉莉酸甲酯对丹参茎叶丹酚酸和丹酚酸B含量的影响

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时珍国医国药 2009年第8期20卷 1921-1923页

作者：李明冯世阳广东药学院.中药学院广东广州510006

目的探讨茉莉酸甲酯（methy jasmonat，MJ）对栽培丹参的药效成分影响，并为丹参地上部分的开发利用提供一定的研究依据。方法采用比色法和HPLC法，以丹酚酸和丹酚酸B为检测指标，对茉莉酸甲酯处理的丹参茎叶样品进行检测。结果丹参种... 详细信息

目的探讨茉莉酸甲酯（methy jasmonat，MJ）对栽培丹参的药效成分影响，并为丹参地上部分的开发利用提供一定的研究依据。方法采用比色法和HPLC法，以丹酚酸和丹酚酸B为检测指标，对茉莉酸甲酯处理的丹参茎叶样品进行检测。结果丹参种苗经茉莉酸甲酯喷施处理后的48h内，其茎叶中丹酚酸和丹酚酸B含量均高于对照，在所测试范围5×10^-9-5×10^-3的浓度中，随浓度的升高而含量增加。结论外施茉莉酸甲酯能促进丹参茎叶中的丹酚酸和丹酚酸B含量的积累，可以考虑在生产中加以应用，并注意今后在丹参的种植及采收中地上部分的利用。

关键词：丹参茉莉酸甲酯丹酚酸丹酚酸B