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Identification of the high-risk area for schistosomiasis transmission in China based on information value and machine learning:a newly data-driven modeling attempt

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Infectious Diseases of Poverty 2021年第3期10卷 113-114页

作者： Yan-Feng Gong ling-Qian zhu Yin-Long li li-Juan Zhang Jing-Bo Xue Shang Xia Shan Lv Jing Xu shi-zhu li National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionChinese Center for Tropical Diseases ResearchHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Centre for Tropical DiseasesNational Center for International Research on Tropical DiseasesShanghai 200025China

Background:Schistosomiasis control is striving forward to transmission interruption and even elimination,evidence-lead control is of vital importance to eliminate the hidden dan gers of *** study attempts to ide ntify... 详细信息

关键词： Schistosomiasis Risk prediction Information value Machine learning China

Economic cost analysis of malaria case management at the household level during the malaria elimination phase in The People’s Republic of China

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Infectious Diseases of Poverty 2016年第1期5卷 424-431页

作者： Shang Xia Jin-Xiang Ma Duo-Quan Wang shi-zhu li David Rollinson Shui-Sen Zhou Xiao-Nong Zhou National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionShanghai 200025People’s Republic of China Key Laboratory of Parasite and Vector Biology Ministry of HealthShanghai 200025People’s Republic of China WHO Collaborating Center for Tropical Diseases Shanghai 200025People’s Republic of China Department of Applied Statistics School of Public HealthGuangzhou Medical UniversityGuangzhou 510182China life Sciences Department The Natural History MuseumCromwell RoadLondon SW75BDUK

Background:In China,malaria has been posing a significant economic burden on *** evaluate malaria economic burden in terms of both direct and indirect costs has its meaning in improving the effectiveness of malaria elimination program in ***:A number of study sites(eight counties in five provinces)were selected from the malaria endemic area in China,representing the different levels of malaria incidence,risk classification,economic development.A number of households with malaria cases(n=923)were surveyed during the May to December in 2012 to collect information on malaria economic *** statistics were used to characterize the basic profiles of selected malaria cases in terms of their gender,age group,occupation and malaria *** malaria economic costs were evaluated by direct and indirect *** were carried out by using the chi-square test(or Z-test)and the Mann-Whitney U test among malaria cases with reference to local/imported malaria patients,hospitalized/out patients,and treatment ***:The average cost of malaria per case was 1691.23 CNY(direct cost was 735.41 CNY and indirect cost was 955.82 CNY),which accounted for 11.1%of a household’s total *** average costs per case for local and imported malaria were 1087.58 CNY and 4271.93 CNY,*** average cost of a malaria patient being diagnosed and treated in a hospital at the county level or above(3975.43 CNY)was 4.23 times higher than that of malaria patient being diagnosed and treated at a village or township hospital(938.80 CNY).Conclusion:This study found that malaria has been posing a significant economic burden on households in terms of direct and indirect *** is a need to improve the effectiveness of interventions in order to reduce the impact costs of malaria,especially of imported infections,in order to eliminate the disease in China.

关键词： Malaria Economic cost analysis Direct costs Indirect costs Health facilities China

Long-distance spread of Tembusu virus,and its dispersal in local mosquitoes and domestic poultry in Chongming Island,China

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Infectious Diseases of Poverty 2023年第3期12卷 94-95页

作者： Yuan Fang Tian Hang li-Min Yang Jing-Bo Xue Ryosuke Fujita Xue-Song Feng Tian-Ge Jiang Yi Zhang shi-zhu li Xiao-Nong Zhou School of Global Health Chinese Center for Tropical Diseases ResearchShanghai Jiao Tong University School of MedicineShanghaiChina National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research)NHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Centre for Tropical DiseasesNational Center for International Research on Tropical DiseasesShanghaiChina Laboratory of Sanitary Entomology Faculty of AgricultureKyushu UniversityFukuokaJapan Shanghai Chongming Dongtan National Nature Reserve ShanghaiChina

Background Chongming Island in China serves as a breeding and shelter point on the East Asian–Australasian *** resting frequency of migratory birds,abundance of mosquito populations,and the popular domestic poultry industry pose a potential risk of mosquito-borne zoonotic *** aim of this study is to explore the role of migratory birds in the spread of mosquito-borne pathogens and their prevalent status on the *** We conducted a mosquito-borne pathogen surveillance in 2021,in Chongming,Shanghai,***‑mately 67,800 adult mosquitoes belonging to ten species were collected to investigate the presence of faviviruses,alphaviruses,and orthobunyaviruses by *** and phylogenetic analyses were conducted to explore the virus genotype and potential nature *** survey was performed by EliSA to characterize Tembusu virus(TMUV)infection among domestic *** Two strains of TMUV and Chaoyang virus(CHAOV)and 47 strains of Quang Binh virus(QBV)were detected in 412 mosquito pools,with the infection rate of 0.16,0.16,and 3.92 per 1000 Culex tritaeniorhynchus,***‑thermore,TMUVs viral RNA was found in serum samples of domestic chickens and faecal samples of migratory *** against TMUV were detected in domestic avian serum samples,generally ranging from 44.07%in pigeons to 55.71%in *** analyses indicated that the TMUV detected in Chongming belonged to Cluster 3,Southeast Asia origin,and most closely related to the CTLN strain,which caused a TMUV outbreak in chickens in Guangdong Province in 2020,but distant from strains obtained previously in Shanghai,which were involved in the 2010 TMUV outbreak in *** We speculate that the TMUV was imported to Chongming Island through long-distance spreading by migratory birds from Southeast Asia,followed by spill over and transmission in mosquitoes and domestic avian species,threatening the local domestic *** addition,the exp

关键词： Chaoyang virus Emerging zoonotic vector-borne disease Insect-specifc favivirus Mosquito-borne virus Quang Binh virus

Approaches being used in the national schistosomiasis elimination programme in China:a review

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Infectious Diseases of Poverty 2017年第1期6卷 475-483页

作者： Le-Ping Sun Wei Wang Qing-Biao Hong shi-zhu li You-Sheng liang Hai-Tao Yang Xiao-Nong Zhou Key Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention Wuxi 214064China Jiangsu Provincial Key Laboratory on Parasites and Vector Control Technology Wuxi 214064China Jiangsu Institute of Parasitic Diseases Wuxi 214064China School of Public Health Fujian Medical UniversityFuzhou 350004China National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionShanghai 200025China Key Laboratory for Parasite and Vector Biology National Health and Family Planning CommissionShanghai 200025China WHO Collaborating Center for Tropical Diseases National Center for International Research on Tropical DiseasesShanghai 200025China

Schistosomiasis japonica,caused by the human blood fluke Schistosoma japonicum,remains a major public health problem in China,although great success has been *** control efforts during the past half-decade,notably the wide implementation of the new integrated strategy with emphasis on control of the source of *** infection across the country since 2004,has greatly reduced *** in humans,livestock,and intermediate host Oncomelania hupensis snails,and transmission control of schistosomiasis was achieved in China in 2015.A two-stage roadmap was therefore proposed for schistosomiasis elimination in 2015,with aims to achieve transmission interruption by 2020 and achieve disease elimination by 2025 in the *** the last two decades,a variety of approaches,which target the epidemiological factors of schistosomiasis japonica have been developed,in order to block the transmission cycle of the *** approaches have been employed in the national or local schistosomiasis control activities,and facilitated,at least in part,the progress of the schistosomiasis elimination ***,we present an approach to control the source of *** infection,three new tools for snail control,three approaches for detecting and monitoring *** infection,and a novel model for health *** approaches are considered to play a great role in the stage moving towards transmission interruption and elimination of schistosomiasis in China.

关键词： Schistosomiasis japonica Schistosoma japonicum Oncomelania hupensis Elimination Snail control Source of infection Health education China

Projecting the proliferation risk of Oncomelania hupensis in China driven by SSPs:A multi-scenario comparison and integrated modeling study

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Advances in Climate Change Research 2022年第2期13卷 258-265页

作者： Yan-Feng GONG Xiao-Kang HU Yu-Wan HAO zhuo-Wei LUO Jia-Xin FENG Jing-Bo XUE Zhao-Yu GUO Yin-Long li li-Juan ZHANG Shang XIA Shan LYU Jing XU shi-zhu li National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research)NHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Centre for Tropical DiseasesNational Center for International Research on Tropical DiseasesShanghai 200025China School of Global Health Chinese Centre for Tropical Diseases ResearchShanghai Jiao Tong University School of MedicineShanghai 200025China

Climate change has been known to cause variations in the geographically suitable areas for the schistosome-transmitting Oncomelania hupensis(***).The spread of snails not only depends on the degree of warming but also on the socioeconomic development of the next few *** socioeconomic pathways(SSPs)published by CMIP6 consider carbon emission pathways as well as influences of distinct types of social development and land use on the regional climate,providing the possibility to accurately evaluate the impact of socioeconomic development and climate variation on the spread of *** study employed SSP126,SSP245,SSP370,and SSP585 and the correlative approach to explore the impacts of climate change and socioeconomic development on the potential diffusion areas for *** in *** results exhibited strong evidence that *** will spread in the north of the middle and lower reaches of the Yangtze River and disappear from a small part of its current southern habitat,whereas in Sichuan and Yunnan,*** may spread slightly to the *** projection also demonstrated that fossil fuel-driven development(SSP585)will be more conducive to the spread of *** breeding sites in the 2030s,whereas the continuous increase in snail breeding habitats under the regional rivalry path(SSP370)may lead to great challenges in snail control in the long term(2020-2080).

关键词： Oncomelania hupensis Shared socioeconomic pathways(SSPs) Climate change China

Research gaps for three main tropical diseases in the People’s Republic of China

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Infectious Diseases of Poverty 2013年第1期2卷 112-125页

作者： Qi Zheng Samantha Vanderslott Bin Jiang li-li Xu Cong-Shan liu Le-Le Huo li-Ping Duan Ning-Bo Wu shi-zhu li Zhi-Gui Xia Wei-Ping Wu Wei Hu Hao-Bing Zhang National Institute of Parasitic Disease Chinese Center for Disease Control and PreventionWHO Collaborating Centre on MalariaSchisostomiasis and FilariasisKey Laboratory of Parasite and Vector BiologyMinistry of Health207 Rui Jin Er RdShanghai 200025People’s Republic of China The Department of Science and Technology Studies University College LondonLondon WC1E 6BTUK

This scoping review analyzes the research gaps of three diseases:schistosomiasis japonica,malaria and *** on available data in the ***,we highlight the gaps between control capacity and prevalence levels,and between diagnostic/drug development and population need for treatment at different stages of the national control *** reviewing the literature from 848 original studies and consultations with experts in the field,the gaps were identified as ***,the malaria research gaps include(i)deficiency of active testing in the public community and no appropriate technique to evaluate elimination,(ii)lack of sensitive diagnostic tools for asymptomatic patients,(iii)lack of safe drugs for mass ***,gaps in research of schistosomiasis include(i)incongruent policy in the implementation of integrated control strategy for schistosomiasis,(ii)lack of effective tools for Oncomelania *** control,(iii)lack of a more sensitive and cheaper diagnostic test for large population samples,(iv)lack of new drugs in addition to ***,gaps in research of echinococcosis include(i)low capacity in field epidemiology studies,(ii)lack of sanitation improvement studies in epidemic areas,(iii)lack of a sensitivity test for early diagnosis,(iv)lack of more effective drugs for short-term *** believe these three diseases can eventually be eliminated in China's Mainland if all the research gaps are abridged in a short period of time.

关键词： Schistosomiasis Malaria Echinococcosis Epidemiology Diagnosis Chemotherapy Research capacity building

Spatio-temporal disparities of Clonorchis sinensis infection in animal hosts in China:a systematic review and meta-analysis

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Infectious Diseases of Poverty 2023年第5期12卷 1-31页

作者： Kai liu Jing Tan Lu Xiao Rui‑Tai Pan Xiao‑Yan Yao Fu‑Yan shi shi‐zhu li Lan‐Hua li School of Public Health Weifang Medical UniversityWeifang 261053China National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionShanghai 200025China Key Laboratory of Parasite and Vector Biology Ministry of HealthWHO Collaborating Center for MalariaSchistosomiasis and FilariasisShanghai 200025China

Background Clonorchis sinensis,one of the most important food-borne zoonotic trematodes,remains prevalent in *** its infection status in animals is crucial for controlling human *** we conducted a systematic review and meta-analysis to focus on the spatio-temporal disparities *** infection in animals in *** Data *** prevalence in snails,the second intermediate hosts,or animal reservoirs in China were extracted from electronic databases including PubMed,Embase,Web of Science,Chinese Wanfang database,CNKI,VIP,and China Biomedical literature database.A random-effects meta-analysis model was utilized to estimate the pooled prevalence in each of the above animal *** analysis and multivariable meta-regression were performed to explore potential sources of heterogeneity across studies and compare the temporal disparity of infection rates between high and low epidemic *** plots were used to depict the biogeographical characteristics of regions *** infection in *** The overall pooled prevalence *** was 0.9%(95%CI:0.6-1.2%)in snails,14.2%(12.7-15.7%)in the second intermediate host,and 14.3%(11.4-17.6%)in animal *** in low epidemic areas(with human prevalence<1%)decreased from 0.6%(0.2-1.2%)before 1990 to 0.0%(0.0-3.6%)after 2010 in snails(P=0.0499),from 20.3%(15.6-25.3%)to 8.8%(5.6-12.6%)in the second intermediate hosts(P=0.0002),and from 18.3%(12.7-24.7%)to 4.7%(1.0-10.4%)in animal ***,no similar decrease in prevalence was observed in high epidemic areas(with human prevalence≥1.0%).*** infections were predominantly reported in areas with altitudes below 2346 m and annual cumulative precipitation above 345 mm and were mostly concentrated in eastern *** There are spatio-temporal disparities in the animal infections *** in different areas of *** infections are primarily concentrated in region

关键词： Clonorchis sinensis China Prevalence Spatio-temporal distribution Biogeographical characteristics Animal host Meta-analysis

Pattern analysis of schistosomiasis prevalence by exploring predictive modeling in Jiangling County,Hubei Province,***

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Infectious Diseases of Poverty 2017年第1期6卷 791-800页

作者： Shang Xia Jing-Bo Xue Xia Zhang He-Hua Hu Eniola Michael Abe David Rollinson Robert Bergquist Yibiao Zhou shi-zhu li Xiao-Nong Zhou National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionKey Laboratory of Parasite and Vector BiologyMinistry of HealthWHO Collaborating Center for Tropical DiseasesShanghai 200025People’s Republic of China Jiangling Institute of Schistosomiasis Control and Prevention Jiangling 434100People’s Republic of China Department of Zoology Natural History MuseumWolfson Wellcome Biomedical LaboratoriesCromwell RoadLondon SW75BDUK Ingerod BrastadSweden Department of Epidemiology School of Public HealthFudan UniversityShanghai 200032People’s Republic of China.

Background:The prevalence of schistosomiasis remains a key public health issue in *** County in Hubei Province is a typical lake and marshland endemic *** pattern analysis of schistosomiasis prevalence in Jiangling County is of significant importance for promoting schistosomiasis surveillance and control in the similar endemic ***:The dataset was constructed based on the annual schistosomiasis surveillance as well the socio-economic data in Jiangling County covering the years from 2009 to 2013.A village clustering method modified from the K-mean algorithm was used to identify different types of endemic *** these identified village clusters,a matrix-based predictive model was developed by means of exploring the one-step backward temporal correlation inference algorithm aiming to estimate the predicative correlations of schistosomiasis prevalence among different *** sampling of faeces from domestic animals,as an indicator of potential schistosomiasis prevalence,was carried out and the results were used to validate the results of proposed models and ***:The prevalence of schistosomiasis in Jiangling County declined year by *** total of 198 endemic villages in Jiangling County can be divided into four clusters with reference to the 5 years’occurrences of schistosomiasis in human,cattle and snail *** each identified village cluster,a predictive matrix was generated to characterize the relationships of schistosomiasis prevalence with the historic infection level as well as their associated impact ***,the results of sampling faeces from the front field agreed with the results of the identified clusters of endemic ***:The results of village clusters and the predictive matrix can be regard as the basis to conduct targeted measures for schistosomiasis surveillance and ***,the proposed models and methods can be modified to investigate the schistosomiasis pre

关键词： Schistosomiasis Clustering Predictive modelling

Effect of pyrite content on chalcopyrite flotation under different regrinding conditions

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 49-57页

作者： Zejun Wang Qing shi Guofan Zhang Yuxuan zhu Binbin li School of Minerals Processing and Bioengineering Central South UniversityChangsha 410083China Key Laboratory of Hunan Province for Clean and Efficient Utilization of Strategic Calcium-containing Mineral Resources Central South UniversityChangsha 410083China

This study aimed to investigate the effect of varying pyrite(Py)content on copper(Cu)in the presence of different regrinding conditions,which were altered using different types of grinding media:iron,ceramic balls,and their mixture,followed by flotation in the cleaner *** flotation performance of rough Cu concentrate can be improved by changing the regrinding conditions based on the Py *** electron microscopy,X-ray spectrometry,ethylenediaminetetraacetic acid disodium salt extraction,and X-ray photoelectron spectroscopy studies illustrated that when the Py content was high,the use of iron media in regrinding promoted the generation of hydrophilic Fe OOH on the surface of Py and improved the Cu *** ceramic medium with a low Py content prevented excessive Fe OOH from covering the surface of chalcopyrite(Cpy).Electrochemical studies further showed that the galvanic corrosion current of Cpy-Py increased with the addition of Py and became stronger with the participation of iron media.

关键词： chalcopyrite regrinding media pyrite galvanic corrosion flotation