检索结果-南通市图书馆

Effect of Cardiopulmonary Bypass on Pulmonary Function in Infants

在线全文

学校读者我要写书评

暂无评论

上海交通大学学报（医学版） 2006年第8期26卷 925-925页

作者： ZHOU Yan-ping CAI Ji-ming shi Zhen-ying CHEN ling XU Zhi-wei SU Zhao-kang Department of Pediatric Thoracic and Cardiovascular Surgery Shanghai Children＇s Medical Center School of Medicine Shanghai Jiaotong University Shanghai 200127 China

Objective To evaluate the effect of the cardiopulmonary bypass (CPB) on the pulmonary function in infants with or withoutpulmonary hypertension in congential ventricular septal defect (VSD). MethodsTwenty infants with VSD were enrolled in the study fromJan. to Dec.2004. They were divided into two groups: pulmonary hypertension group and non-pulmonary hypertension group, ten infantsrespectively. Pulmonary function parameters were measured before CPB and 3, 6, 9, 12, 15, 18, 21, 24h after CPB, the following datawere recorded: duration for mechanical ventilation (Tmv) and staying in the cardiac intensive care unit (Tcicu) after cardiac *** Before CPB, the pulmonary function parameters in non-pulmonary hypertension group were more superior than in pulmonary hy-pertension group (P<0.01). By contraries, the pulmonary function parameters in every time stage after CPB statistically significant de-creased in non-pulmonary hypertension group (P<0.05), especially at 6, 9, and 15h after CPB (P<0.01). In pulmonary hyperten-sion group, the pulmonary function parameters in 3h after CPB were more improved than before CPB, though there was no statistical sig-nificance. But they had statistically significant decreased at9, 12, 15h after CPB (P<0.05). There was a similar change in pulmonaryfunction between two groups at 21, 24h after CPB. Conclusion Exposure to CPB adversely affects pulmonary function after surgicalrepair of VSD in infants. We consider that the benefits of the surgical correction in infants with pulmonary hypertension outweight the neg-ative effects of CPB on pulmonary function. We should improve cardiac function to avoid the presence of the nadir trough in pulmonaryfunction. The infants with pulomonary hypertension also have ability to wean from mechanical ventilation as soon as possible, if the hemo-dynamics is stable, and without the responsive pulmonary hypertension or pulmonary hypertension crisis after surgical repair.

关键词： cardiopulmonary bypass pulmonary hypertension pulmonary function infant

2014年山东省滨州市饮用水源地周边土壤环境质量对饮用水的影响分析

在线全文

学校读者我要写书评

暂无评论

环境卫生工程 2017年第3期25卷 55-57页

作者：任英史玲滨州市环境保护监测站山东滨州256600 济南市生活废弃物处理中心山东济南250031

选取山东省滨州市无棣月湖水库和沾化思源湖水库为研究对象,分析其周边土壤环境质量情况,结果表明:2个饮用水源地周边10个监测点位土壤pH为7.06~7.21;阳离子交换量为7.9~14.2 cmol/kg;有机质含量为2.9~23.5 g/kg。无机物和有机物项目单... 详细信息

选取山东省滨州市无棣月湖水库和沾化思源湖水库为研究对象,分析其周边土壤环境质量情况,结果表明:2个饮用水源地周边10个监测点位土壤pH为7.06~7.21;阳离子交换量为7.9~14.2 cmol/kg;有机质含量为2.9~23.5 g/kg。无机物和有机物项目单项污染指数均小于1,综合污染指数(有机无机综合值)均小于0.7,属于清洁安全等级。

关键词：土壤污染饮用水无机物有机质地表水水域面积

在线全文

学校读者我要写书评

暂无评论

基于环境约束的电源结构优化研究

中国电力 2009年第9期42卷 16-19页

作者：施应玲刘媛媛华北电力大学工商管理学院北京102206

为实现经济增长、满足电力需求和环境保护的目标,运用多目标规划的理论和方法,构建了社会经济与环境协调发展的电源结构优化模型,运用此模型对2010年中国电源结构进行了优化,对基于不同情景预测的2015、2020年用电量需求下污染物排放量... 详细信息

为实现经济增长、满足电力需求和环境保护的目标,运用多目标规划的理论和方法,构建了社会经济与环境协调发展的电源结构优化模型,运用此模型对2010年中国电源结构进行了优化,对基于不同情景预测的2015、2020年用电量需求下污染物排放量的情况进行了分析。研究表明:在现有装机容量的前提下,以经济优先对电源结构进行优化,火力发电所占比例需降至82.04%,水电所占比例达到14.98%,烟尘排放量需降至0.894g/(kW·h)才能达到总量减排10%的目标。以环境优先的电源结构优化,在电力供应总量满足全社会用电量的基础上,火电所占比例需大幅下降,降至61.11%,水电所占比例升至35.03%。

关键词：电源结构优化环境约束

Ce，Pr离子双掺LuAG透明陶瓷制备及光学性能

在线全文

学校读者我要写书评

暂无评论

无机材料学报 2016年第10期31卷 1099-1102页

作者：周鼎施鹰范灵聪林德宝孙泽清徐家跃上海大学材料科学与工程学院电子信息材料系上海200072 上海应用技术大学材料科学与工程学院晶体生长研究所上海201418

以NH_4OH+NH_4HCO_3混合溶液作为复合沉淀剂,利用反向滴定共沉淀法制备了不同浓度Ce,Pr共掺杂LuAG沉淀前驱体,并研究了Pr掺杂浓度为0.25at%,Ce掺杂浓度分别为0、0.1at%、0.2at%和0.3at%的LuAG透明陶瓷的光学性能。沉淀前驱体经马弗炉120... 详细信息

以NH_4OH+NH_4HCO_3混合溶液作为复合沉淀剂,利用反向滴定共沉淀法制备了不同浓度Ce,Pr共掺杂LuAG沉淀前驱体,并研究了Pr掺杂浓度为0.25at%,Ce掺杂浓度分别为0、0.1at%、0.2at%和0.3at%的LuAG透明陶瓷的光学性能。沉淀前驱体经马弗炉1200℃煅烧2 h后所得粉体的分散性较好,一次颗粒尺寸约为60 nm。该粉体经干压和冷等静压成型后,在H_2气氛1800℃下烧结6 h制备出透明陶瓷,经双面抛光后透明陶瓷在800 nm波长处直线透过率达到82%。X射线激发的发射光谱表明,共掺使Pr离子5d-4f的发射能量传递给Ce离子,有助于提高LuAG透明陶瓷在550 nm发光中心的发光强度。0.2at%Ce和0.25at%Pr共掺杂时,透明陶瓷的发光强度达到最大。

关键词： Ce离子 Pr离子 LuAG透明陶瓷光学性能

Variable phenotypes and outcomes associated with the MMACHC c.482G>A mutation:follow-up in a large CblC disease cohort

在线全文

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2024年第8期20卷 848-858页

作者： Sheng-Nan Wu Hui-Shu E Yue Yu shi-ying ling Li-Li Liang Wen-Juan Qiu Hui-Wen Zhang Rui-Xue Shuai Hai-Yan Wei Chi-Ju Yang Peng Xu Xi-Gui Chen Hui Zou Ji-Zhen Feng Ting-Ting Niu Hai-Li Hu Kai-Chuang Zhang De-Yun Lu Zhu-Wen Gong Xia Zhan Wen-Jun Ji Xue-Fan Gu Yong-Xing Chen Lian-Shu Han Department of Endocrinology and Metabolism Henan Key Laboratory of Children’s Genetics and Metabolic DiseasesChildren’s Hospital Affiliated to Zhengzhou UniversityHenan Children’s HospitalZhengzhou Children’s HospitalNo.255 Gangdu StreetZhengzhouChina Department of Pediatric Endocrinology and Genetics Fujian Children’s HospitalFuzhouChina The Center for Pediatric Liver Diseases Children’s HospitalFudan UniversityShanghaiChina Department of Pediatric Endocrinology/Genetics Shanghai Institute for Pediatric ResearchXinhua HospitalSchool of MedicineShanghai Jiao Tong UniversityNo.1665 Kongjiang RoadShanghaiChina Department of Pediatrics Second Affiliated Hospital of Naval Medical UniversityShanghaiChina Center of Neonatal Disease Screening Jining Maternal and Child Health Care HospitalJiningChina Center of Neonatal Disease Screening Jinan Maternal and Child Health Care HospitalJinanChina Center of Neonatal Disease Screening Shijiazhuang Maternal and Child Health Care HospitalShijiazhuangChina Center of Neonatal Disease Screening Shandong Maternal and Child Health Care HospitalJinanChina Center of Neonatal Disease Screening Hefei Maternal and Child Health Care HospitalHefeiChina

Background The aim of this study was to characterize the variable phenotypes and outcomes associated with the methylmalonic aciduria and homocystinuria type C protein gene(MMACHC)c.482G>A mutation in 195 Chinese cases with CblC *** We carried out a national,retrospective multicenter study of 195 Chinese patients with CblC disease attributable to the MMACHC c.482G>A variant either in a homozygous or compound heterozygous *** control group consisted of 200 patients diagnosed with CblC disease who did not possess the c.482G>A *** features,including disease onset,symptoms,biochemical metabolites,gene mutation,and follow-up outcomes were reviewed and analyzed in *** median follow-up period spanned 3 years and 8 months,with a range of 1 year and 2 months to 12 years and 10 *** Among 195 patients carrying the c.482G>A variant,125(64.1%)cases were diagnosed by newborn screening(NBS),60(30.8%)cases were detected due to disease onset,and 10(5.1%)cases were identified from sibling *** hundred and seventeen(93.6%)individuals who were diagnosed by NBS,and nine patients who came from sibling diagnoses remained asymptomatic in this *** 69 symptomatic patients of the c.482G>A group,more patients presented with later onset,and the top six common clinical symptoms at disease onset were developmental delay(59.4%),lower limb weakness and poor exercise tolerance(50.7%),cognitive decline(37.7%),gait instability and abnormal posture(36.2%),seizures(26.1%),and psychiatric and behavioral disturbances(24.6%).In the 159 symptomatic patients lacking c.482G>A variants,the most frequently observed clinical manifestations at disease onset included developmental delay(81.8%),lethargy and feeding difficulty(62.9%),lower limb weakness and poor exercise tolerance(54.7%),prolonged neonatal jaundice(51.6%),vomiting(47.2%),and seizures(32.7%).Before treatment,the levels of blood propionylcarnitine,propionylcarnitine/acetylcarnitine ratio

关键词： c.482G>A CblC disease MMACHC gene Newborn screening Outcome

Regulation and function of endoplasmic reticulum autophagy in neurodegenerative diseases

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第1期20卷 6-20页

作者： Xiu-Yun Zhao De-En Xu Ming-Lei Wu Ji-Chuan Liu Zi-ling shi Quan-Hong Ma Department of Neurology and Clinical Research Center of Neurological Disease the Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Neuroscience&Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases Soochow UniversitySuzhouJiangsu ProvinceChina Department of Neurology Jiangnan University Medical CenterWuxiJiangsu ProvinceChina

The endoplasmic reticulum,a key cellular organelle,regulates a wide variety of cellular *** reticulum autophagy,one of the quality control systems of the endoplasmic reticulum,plays a pivotal role in maintaining endoplasmic reticulum homeostasis by controlling endoplasmic reticulum turnover,remodeling,and *** this review,we briefly describe the endoplasmic reticulum quality control system,and subsequently focus on the role of endoplasmic reticulum autophagy,emphasizing the spatial and temporal mechanisms underlying the regulation of endoplasmic reticulum autophagy according to cellular *** also summarize the evidence relating to how defective or abnormal endoplasmic reticulum autophagy contributes to the pathogenesis of neurodegenerative *** summary,this review highlights the mechanisms associated with the regulation of endoplasmic reticulum autophagy and how they influence the pathophysiology of degenerative nerve *** review would help researchers to understand the roles and regulatory mechanisms of endoplasmic reticulum-phagy in neurodegenerative disorders.

关键词： autophagy endoplasmic reticulum endoplasmic reticulum autophagy endoplasmic reticulum quality control system endoplasmic reticulum receptors endoplasmic reticulum-associated degradation neurodegeneration neurodegenerative disease selective autophagy unfolded protein response

在线全文

学校读者我要写书评

暂无评论

中国电力消费CO_2排放强度分解分析

华东电力 2009年第8期37卷 1241-1245页

作者：施应玲刘媛媛常豫州华北电力大学工商管理学院北京102206 河南省电力公司洛阳供电公司河南洛阳471009

为明确电力消费与CO2排放之间的潜在关系，利用分解分析的理论，运用固定基年的AdaptiveWeightingDivisiaIndex方法以发电、工业、交通运输业、民用和服务业、其他行业五种行业分类为基础，对1990—2005年间中国CO2排放强度进行了分解... 详细信息

为明确电力消费与CO2排放之间的潜在关系，利用分解分析的理论，运用固定基年的AdaptiveWeightingDivisiaIndex方法以发电、工业、交通运输业、民用和服务业、其他行业五种行业分类为基础，对1990—2005年间中国CO2排放强度进行了分解分析研究，并将其分解成分行业的电力消费结构效应因素和CO2排放强度效应因素。分析结果表明，15年间中国总的单位用电量CO2排放强度有了大幅的降低，降低比率达43．21％。两影响因素中用电结构效应对总排放强度的降低起到抑制的作用，而分行业单位用电量排放强度效应则推动了总排放强度的下降，其中又以工业、发电业的影响最为突出。

关键词： CO2排放量用电量排放强度分解分析

中国传统艺术在旅游产品设计中的运用研究——以扬州剪纸为例

在线全文

学校读者我要写书评

暂无评论

邢台职业技术学院学报 2017年第4期34卷 97-101页

作者：陈皎月施玲鹰扬州市职业大学江苏扬州225000

剪纸与旅游产品的结合实现了民族艺术的传承,也开创了旅游产品本土化的双赢局面。文章从扬州旅游产品发展现状和扬州剪纸艺术的特点出发,探索融入扬州剪纸艺术的扬州旅游产品设计开发新思路,以期对民间艺术文化的传承和地方旅游产品的... 详细信息

剪纸与旅游产品的结合实现了民族艺术的传承,也开创了旅游产品本土化的双赢局面。文章从扬州旅游产品发展现状和扬州剪纸艺术的特点出发,探索融入扬州剪纸艺术的扬州旅游产品设计开发新思路,以期对民间艺术文化的传承和地方旅游产品的开发有所启示与借鉴。

关键词：扬州剪纸旅游产品运用研究

基于自适应种群粒子群的光伏全局MPPT研究

在线全文

学校读者我要写书评

暂无评论

电力电子技术 2017年第5期51卷 27-30页

作者：石季英凌乐陶薛飞李雅静天津大学电气与自动化工程学院天津300072 国网宁夏电力公司电力科学研究院宁夏银川750002

局部遮蔽条件(PSC)下,传统最大功率点跟踪(MPPT)算法会陷入局部极值,智能算法追踪时间过长。针对上述问题,提出了一种基于自适应种群粒子群算法(APPSO)的MPPT控制方法,引入全局和局部粒子密度的概念,并设计了两种自适应调整的粒子种群... 详细信息

局部遮蔽条件(PSC)下,传统最大功率点跟踪(MPPT)算法会陷入局部极值,智能算法追踪时间过长。针对上述问题,提出了一种基于自适应种群粒子群算法(APPSO)的MPPT控制方法,引入全局和局部粒子密度的概念,并设计了两种自适应调整的粒子种群数量的机制。对该方法与常规粒子群算法(PSO)在均匀光照和PSC下分别进行了对比。仿真和实验结果均表明,在PSC下APPSO可迅速、准确地追踪到全局最大功率点(GMPP),追踪时间仅为PSO的50%左右。

关键词：最大功率点追踪粒子群算法遮蔽情况