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Establishment of an Iron Deficiency Model by Iron Depletion in Pregnant Rats

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Biomedical and Environmental Sciences 2024年第2期37卷 210-215页

作者： CHEN Xi HAN Chao ZHAO Jin Peng SHEN shi WANG Li Yuan REN Shou WANG tong Lei MA Yan XU Ze Chao HUO jun Sheng Key Laboratory of Trace Element Nutrition National Health Commission of the People’s Republic of ChinaNational Institute for Nutrition and HealthChinese Center for Disease Control and PreventionBeijing 100050China

Anemia,a global public health problem,has significant adverse consequences on the cognitive development of children and the work capacity of adults;affecting social and economic development.Globally,roughly 43%of children under five years of age,38%of pregnant women,and 29%of nonpregnant women had anemia.Anemia during pregnancy significantly increases the risk of low birth weight and preterm birth.A 10 g/L increase in hemoglobin has been estimated to decrease the risk of maternal and perinatal mortality by 29%and 28%.

关键词： mortality pregnancy anemia

Wettability of different clay mineral surfaces in shale:Implications from molecular dynamics simulations

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Petroleum Science 2023年第2期20卷 689-704页

作者： Kan-Yuan shi jun-Qing Chen Xiong-Qi Pang Fu-Jie Jiang Sha-Sha Hui Zhen-Cheng Zhao Di Chen Qi Cong tong Wang Hui-Yi Xiao Xiao-Bin Yang Yu-Ying Wang State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing102249China College of Geosciences China University of PetroleumBeijing102249China Basic Research Center for Energy Interdisciplinary College of ScienceChina University of PetroleumBeijing102249China Beijing Key Laboratory of Optical Detection Technology for Oil and Gas College of ScienceChina University of PetroleumBeijing102249China

Shale contains a lot of clay minerals. Clay minerals mainly exist in nano- and micro-meter sized particles, and the pore structure is complex, which leads to its extremely complex wettability. The surface wettability of clay minerals significantly affects the oil and gas-bearing capacity of shale reservoirs. Therefore, studying the wettability of common clay minerals in shale at the nanoscale is of great significance for shale hydrocarbon exploration and development. In this study, the wetting behavior of water in n-hexane and toluene on different clay mineral surfaces at the nanoscale was systematically studied using Molecular dynamics (MD) simulation. And the influencing factors of wettability were analyzed. Through the analysis of the morphological changes of water, relative concentration of water, RDF and interaction energy, it is concluded that the following order of water wettability on the surfaces of clay minerals: montmorillonite > chlorite > kaolinite > illite. Through the analysis of interaction energy, it is concluded that the hydrophilicity of four clay minerals is stronger than that of lipophilicity. And the main interactions between water and oil and the mineral surfaces were van der Waals force and electrostatic force. In addition, the temperature, liquid hydrocarbon type, and mineralization of water affected the wettability of clay minerals. The concentration of water on the surfaces of montmorillonite, kaolinite, and illite decreased with increasing temperature, and the water wettability decreased. At 298 K, the hydrophilicity of the surfaces of the clay minerals in toluene follows the order montmorillonite > chlorite > kaolinite > illite. The higher the NaHCO3 concentration in water, the weaker the wettability of the clay mineral surfaces to water. By comparing the previous experimental results with the MD simulation results, similar wetting characteristics were obtained, and the reliability of the simulation results was verified. MD simulation was used to explore the water wetting of the surfa

关键词： Shale Molecular dynamics Nanoscale Wettability Clay minerals

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普遍主义之种种

华东师范大学学报（哲学社会科学版） 2008年第6期40卷 44-50,57页

作者：童世骏上海社会科学院上海200020

为了更好地理解"普遍主义"以及类似的概念,更好地理解、参与和应对与此有关的学术界内外的争论,有必要对普遍主义的种种类型进行分析。普遍主义有宗教的和世俗的;在世俗普遍主义中,有以观念的可接受性程度为核心的普遍主义,也有以观念... 详细信息

为了更好地理解"普遍主义"以及类似的概念,更好地理解、参与和应对与此有关的学术界内外的争论,有必要对普遍主义的种种类型进行分析。普遍主义有宗教的和世俗的;在世俗普遍主义中,有以观念的可接受性程度为核心的普遍主义,也有以观念的涉及范围为核心的普遍主义。在以观念的可接受性程度为核心的普遍主义中,有以单个价值为核心的价值普遍主义和以价值体系或诸多价值排序方式为核心的文化普遍主义;在价值普遍主义中,有强调交往的普遍意义的对话普遍主义和以为某人或某民族是可以单方面或独白地决定什么东西具有普遍有效性的独白普遍主义。为了在主张普遍主义的同时避免西方中心论,必须把本质主义的普遍主义与建构主义的普遍主义区分开来,通过观念层面的沟通和现实层面的来往这两个方面的良性互动,而在未来的共同实践中建构起包容多样性的普遍性。

关键词：普遍主义特殊主义对话非西方中心论建构主义

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提高国家文化软实力：内涵、背景和任务

毛泽东邓小平理论研究 2008年第4期 1-8页

作者：童世骏上海社会科学院教育部社会科学委员会委员

国家文化软实力是"软实力"的一个方面,是以文化为基础的国家软实力。"提高国家文化软实力"任务的提出有其国际和国内背景,实现"提高国家文化软实力"的目标,包括以下四方面的任务:同步发展物质文明和精神文明,彰显中华民族的国际自信力;... 详细信息

国家文化软实力是"软实力"的一个方面,是以文化为基础的国家软实力。"提高国家文化软实力"任务的提出有其国际和国内背景,实现"提高国家文化软实力"的目标,包括以下四方面的任务:同步发展物质文明和精神文明,彰显中华民族的国际自信力;统筹国内发展和对外开放,提升国家形象的国际亲和力;结合传统智慧和现代文明,扩大民族文化的国际影响力;推进文化创新和产业升级,提高文化产业的国际竞争力。

关键词：文化软实力国际关系党的十七大

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审美活动的构成要素分析

新疆师范大学学报（哲学社会科学版） 2020年第5期41卷 131-137页

作者：张师童李骏祥新疆师范大学美术学院新疆乌鲁木齐830054 商务部国际贸易经济合作研究院北京100710

美学研究在人类思想史中主要围绕艺术创造、美感、陶冶(社会功用)展开,在庞杂多样的艺术形式与各不相同的美学原理间,审美共性与差异性的矛盾始终不能调和。文本从人类学及基因学的成果中推导人类审美主体机能的同一性,在原始艺术与文... 详细信息

美学研究在人类思想史中主要围绕艺术创造、美感、陶冶(社会功用)展开,在庞杂多样的艺术形式与各不相同的美学原理间,审美共性与差异性的矛盾始终不能调和。文本从人类学及基因学的成果中推导人类审美主体机能的同一性,在原始艺术与文明化艺术的比对中,剖析审美活动的共性因素和差异性因素。在艺术史的既成事实中,结合文明、文化、生存结构与审美活动的关系,分析审美活动的本质。

关键词：美学艺术史先天美感文化美感

Preliminary Evaluation of Hemodynamic Effects of Fontan Palliation on Renal Artery Using Computational Fluid Dynamics

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Congenital Heart Disease 2023年第1期18卷 41-55页

作者： Jinlong Liu Jing shi Weiru Luo Zhirong tong Lefei Yang Peixuan Sun Tianyi Li jun Du Qian Wang Institute of Pediatric Translational Medicine Shanghai Children’s Medical CenterSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina Shanghai Engineering Research Center of Virtual Reality of Structural Heart Disease Shanghai Children’s Medical CenterSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina Department of Imaging Diagnosis Center Shanghai Children's Medical CenterSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina

Background:The assessment of renal function is important to the prognosis of patients needing Fontan palliation due to the reconstructed compromised circulation.To know the relationship between the kidney perfusion and hemodynamic characteristics during surgical design could reduce the risk of acute kidney injury(AKI)and the postoperative complications.However,the issue is still unsolved because the current clinical evaluation methods are unable to predict the hemodynamic changes in renal artery(RA).Methods:We reconstructed a three-dimensional(3D)vascular model of a patient requiring Fontan palliation.The technique of computational fluid dynamics(CFD)was utilized to explore the changes of RA hemodynamics under different possible blood flow rates.The relationship between the kidney perfusion and hemodynamic characteristics was investigated.Results:The calculated results indicated the declined tendency of the pressure and pressure drop as the flow rate decreased.When the flow rate decreased to two-thirds of its baseline,both the pressure of left renal artery(LRA)and the pressure of right renal artery(RRA)dipped below 50%,and the pressure of RRA fell more quickly than that of LRA.Uneven distribution of WSS was observed on the trunk of RA,and the lowest WSS was found at the distal of RA.The average WSS in RA dropped to around 50%as the flow rate reached one-third of its baseline.Conclusions:As a promising approach,CFD can be utilized to quantitatively evaluate the hemodynamic characteristics of RA and contribute to offsetting the drawbacks of clinical assessments of renal function,to help realize better prognosis for the patients with Fontan palliation.

关键词： Renal artery Fontan palliation hemodynamics computational fluid dynamics surgical design

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基于混合距离学习的双指数模糊C均值算法

软件学报 2010年第8期21卷 1878-1888页

作者：王骏王士同南京理工大学计算机科学与技术学院江苏南京210094 江南大学信息工程学院江苏无锡214122 南京大学计算机软件新技术国家重点实验室江苏南京210093

提出了一种基于DI-FCM(double indices fuzzy C-means)算法框架的无监督距离学习算法——基于混合距离学习的双指数模糊C均值算法HDDI-FCM(double indices fuzzy C-m eans with hybrid distance).数据集未知距离度量被表示为若干已有距... 详细信息

提出了一种基于DI-FCM(double indices fuzzy C-means)算法框架的无监督距离学习算法——基于混合距离学习的双指数模糊C均值算法HDDI-FCM(double indices fuzzy C-m eans with hybrid distance).数据集未知距离度量被表示为若干已有距离的线性组合,然后执行HDDI-FCM,在对数据集进行有效聚类的同时进行距离学习.为了保证迭代算法收敛,引入了Steffensen迭代法来改进计算簇中心点的迭代公式.讨论了算法中参数的选择.基于UCI(University of California,Irvine)数据集的实验结果表明该算法是有效的.

关键词：距离学习聚类模糊C均值算法混合距离 Steffensen迭代法

Hepatocellular carcinoma: Clinical study of long-term survival and choice of treatment modalities

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World Journal of Gastroenterology 2013年第23期19卷 3649-3657页

作者： Ke-tong Wu Cun-Chuan Wang Li-Gong Lu Wei-Dong Zhang Fu-jun Zhang Feng shi Chuan-Xing Li Department of Medical Imaging and Interventional Radiology Cancer Center and State Key Laboratory of Oncology in South China Sun Yat-sen University the Center of Minimally Invasive Surgery First Affiliated Hospital of Jinan University Cancer Center Guangdong General Hospital

AIM: To analyze the prognostic factors of 5-year survival and 10-year survival in hepatocellular carcinoma (HCC) patients, and to explore the reasons for longterm survival and provide choice of treatment modalities for HCC patients. METHODS: From January 1990 to October 2012, 8450 HCC patients were included in a prospective database compiled by the Information Center after hospital admission. Long-term surviving patients were included in a 10-year survival group (520 patients) and a 5-year survival group (1516 patients) for analysis. The long-term survival of HCC patients was defined as the survival of 5 years or longer. Clinical and biologic variables were assessed using univariate and multivariate analyses. The survival of patients was evaluated by follow-up data. RESULTS: The long-term survival of HCC patients was associated with the number of lesions, liver cirrhosis and Child-Pugh classification. It was not found to be associated with tumor diameter, histological stage, and pretreatment level of serum α-fetoprotein. The differences in clinical factors between the 5-year survival and the 10-year survival were found to be the number of lesions, liver cirrhosis, Child-Pugh classification, and time elapsed until first recurrence or metastasis. The survival period of different treatment modalities in the patients who survived for 5 years and 10 years showed significant differences: (in order of significance) surgery alone > surgery-transcatheter arterial chemoembolization (TACE) > TACE-radiofrequency ablation (RFA) > TACE alone > surgery-TACE-RFA. The 10-year survival of HCC patients was not associated with the choice of treatment modality.CONCLUSION: This retrospective study elucidated survival outcomes, prognostic factors affecting survival and treatment modalities in HCC patients.

关键词： Hepatocellular carcinoma Surgery Radiofrequency ablation Transcatheter arterial chemoembolization Statistical analysis Clinical study

白洋淀流域农村河长制二元递进共治机制及途径研究

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中国农村水利水电 2022年第5期 45-50,56页

作者：史艺萌苑紫彤王军河北农业大学河北保定071000

白洋淀流域水治理进入河长制实施新时期,存在政策落地不彻底、公众参与不足等问题。基于乡村治理理论,以白洋淀淀区288份农户有效调研问卷为样本,运用二元logistic模型分析农户个人特征、心理认知、政府手段、权利保障对农户参与水环境... 详细信息

白洋淀流域水治理进入河长制实施新时期,存在政策落地不彻底、公众参与不足等问题。基于乡村治理理论,以白洋淀淀区288份农户有效调研问卷为样本,运用二元logistic模型分析农户个人特征、心理认知、政府手段、权利保障对农户参与水环境治理意愿的影响,研究结果表明:①个人特征方面:农户个人特征对参与水环境治理意愿影响不显著;②心理认知方面:农户水治理付费意愿对参与水环境治理有显著负向影响,农户水环境治理现状认知对其影响不显著;③政策手段方面:农户对政府水治理政策和回应人民诉求的满意程度对参与水环境治理意愿有显著正向影响;④权利保障方面:政府对农户水环境民生权和知情权的保障对参与水环境治理意愿有显著正向影响,政府对水环境诉讼权的保障对其影响不显著。因此提出政府与农户参与二元水环境共治递进机制,以及政策横纵递进,农民参与“三民化”递进并渐向多元善治型升级的河长制演进路径。

关键词：白洋淀流域农村河长制政府与农户递进共治