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Acta Mathematicae Applicatae Sinica 2018年第3期34卷 553-565页

作者： shi-jie wang Chuan-wei ZHANG Xue-jun wang Wen-sheng wang School of Mathematic Sciences Anhui University Hefei 230601 China School of Economics Hangzhou Dianzi University Hangzhou 310018 China

Consider a discrete-time risk model with insurance and financial risks in a stochastic economic environment. Assume that the insurance and financial risks form a sequence of independent and identically distributed random vectors with a generic random vector following a wide type of dependence structure. An asymptotic formula for the finite-time ruin probability with subexponential insurance risks is derived. In doing so, the subexponentiality of the product of two dependent random variables is investigated simultaneously.

关键词： discrete-time risk model finite-time ruin probability subexponentiality product dependence structure

Survival after repeat hepatectomy for recurrent colorectal liver metastasis: A review and meta-analysis of prognostic factors

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Hepatobiliary & Pancreatic Diseases International 2019年第4期18卷 313-320页

作者： shi-jie wang Xiao-Ying Si Zhi-Bin Cai Yan-Ming Zhou Department of Hepatobiliary and Pancreatovascular Surgery First Affiliated Hospital of Xiamen University

Background:Frequent recurrent hepatic metastasis after hepatic metastasectomy is a major obstacle in the treatment of colorectal liver metastasis(CRLM).We performed the present systematic review to evaluate the short-and long-term outcomes after repeat hepatectomy for recurrent CRLM and determine factors associated with survival in these *** sources:An electronic search of PubMed database was undertaken to identify all relevant peerreviewed papers published in English between January 20 0 0 and July *** ratios(HR)with 95%confidence interval(95%CI)were calculated for prognostic factors of overall survival(OS).Results:The search yielded 34 studies comprising 3039 patients,with a median overall morbidity of 23%(range 8%–71%),mortality of 0(range 0–6%),and 5-year OS of 42%(range 17%–73%).Pooled analysis showed that primary T3/T4 stage tumor(HR=1.94;95%CI:1.04–3.63),multiple tumors(HR=1.49;95%CI:1.10–2.01),largest liver lesion≥5 cm(HR=1.89;95%CI:1.11–3.23)and positive surgical margin(HR=1.80;95%CI:1.09–2.97)at initial hepatectomy,and high serum level of carcinoembryonic antigen(HR=1.87;95%CI:1.27–2.74),disease-free interval≤12 months(HR=1.34;95%CI:1.10–1.62),multiple tumors(HR=1.64;95%CI:1.32–2.02),largest liver lesion≥5 cm(HR=1.85;95%CI:1.34–2.56),positive surgical margin(HR=2.25;95%CI:1.39–3.65),presence of bilobar disease(HR=1.62;95%CI:1.19–2.20),and extrahepatic metastases(HR=1.60;95%CI:1.23–2.09)at repeat hepatectomy were significantly associated with poor OS.

关键词： Colorectal cancer Metastasectomy Prognosis Meta-analysis

Long-term outcomes of combined hepatocellular-cholangiocarcinoma after hepatectomy or liver transplantation: A systematic review and meta-analysis

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Hepatobiliary & Pancreatic Diseases International 2019年第1期18卷 12-18页

作者： De-Bang Li Xiao-Ying Si shi-jie wang Yan-Ming Zhou Department Ⅲ of General Surgery the First Hospital of Lanzhou University Department of Hepatobiliary & Pancreatovascular Surgery First Affiliated Hospital of Xiamen University

Background: Combined hepatocellular-cholangiocarcinoma(cHCC-CC) is a rare primary liver malignancy. We conducted a systematic review and meta-analysis to assess the evidence available on the long-term outcomes of cHCC-CC patients after either hepatectomy or liver transplantation(LT). Data Sources: Relevant studies published between January 2000 and January 2018 were identified by searching Pub Med and Embase and reviewed systematically. Data were pooled using a random-effects model. Results: A total of 42 observational studies involving 1691 patients(1390 for partial hepatectomy and 301 for LT) were included in the analysis. The median tumor recurrence and 5-year overall survival(OS) rates were 65%(range 38%–100%) and 29%(range 0–63%) after hepatectomy versus 54%(range 14%–93%) and 41%(range 16%–73%) after LT, respectively. Meta-analysis found no significant difference in OS and tumor recurrence between LT and hepatectomy groups. Conclusion: Hepatectomy rather than LT should be considered as the prior treatment option for cHCC-CC.

关键词： Combined hepatocellular-cholangiocarcinoma Liver transplantation Hepatectomy Treatment Prognosis

Proposal of a new T-stage classification system for ampullary carcinoma based on Surveillance,Epidemiology and End Result(SEER)database

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Hepatobiliary & Pancreatic Diseases International 2021年第6期20卷 568-573页

作者： shi-jie wang Yi-Fei Li Shan Liao You-Zhu Wei Yan-Ming Zhou Department of Hepatobiliary and Pancreatovascular Surgery First Affiliated Hospital of Xiamen UniversityXiamen 361003China

Background:Tumor size is still considered a useful prognostic factor in currently available tumor-nodemetastasis(TNM)classification staging systems for most solid tumors,but the significance of tumor size on the prognosis of ampullary carcinoma remains *** aim of the current study was to propose a new T-stage classification system for ampullary carcinoma to address the impact of tumor size on the prognostic ***:Using the Surveillance,Epidemiology,and End Results(SEER)database,we identified 1080 patients with ampullary carcinoma who underwent radical surgical resection between 2004 and *** on the results obtained from analysis of various clinicopathologic factors,a new T-stage classification system was ***:Among the 1080 patients,618 were men and 462 were women,with a median tumor size of 2.3(range 0.1–12)*** the 7 th edition of the American Joint Committee on Cancer(AJCC)staging manual,we noticed significant differences in overall survival(OS)between T2 vs.T3 tumors(P<0.001)and T3 vs.T4 tumors(P=0.002),but failed to observe significant differences between T1 vs.T2 tumors(P=0.498)in our pair-wise *** the newly developed T-stage classification system,we were able to differentiate significant differences in OS between T1 vs.T2 tumors(P=0.032),T2 vs.T3 tumors(P<0.001)and T3 vs.T4 tumor(P=0.003)in all pair-wise *** c-index of the new staging system was 0.653(95%CI:0.629–0.677),showing a better discriminatory power than the 0.636 of the 7 th AJCC staging system(95%CI:0.612–0.660).Conclusions:The new T-stage classification system described herein can better differentiate prognostic outcomes after radical resection in patients with ampullary carcinoma by incorporating tumor size and depth of tumor infiltration.

关键词： Ampullary carcinoma Cancer staging SEER

Zircon U-Pb-Hf isotopic and geochemical characteristics of the Xierzi biotite monzogranite pluton,Linxi,Inner Mongolia and its tectonic implications

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Geoscience Frontiers 2018年第2期9卷 505-516页

作者： Qing-Bin Guan Zheng-Hong Liu Xing-An wang Bin wang shi-jie wang Yu-Song Chen Zhi-Qiang Feng College of Earth Sciences Jilin UniversityChangchun 130061China College of Geographical Sciences Northeast Normal UniversityChangchun 130024China Shandong Provincial No.6 Exploration Institute of Geology and Mineral Resources Weihai 264209China Department of Earth Science and Engineering Taiyuan University of TechnologyTaiyuan 030024China

The opening, subduction and final closure of the Paleo-Asian Ocean led to the formation of the Central Asian Orogenic Belt. Controversy has long surrounded the timing of final closure of the Paleo-Asian Ocean. Here we present zircon U-Pb ages and petrological, geochemical and in situ Hf isotope data for the Xierzi biotite monzogranite pluton, Linxi, SE Inner Mongolia. U-Pb dating of zircon by LA-ICP-MS yields a middle Permian emplacement age(268.7 ± 2.3 Ma) for the Xierzi pluton that is dominated by biotite monzogranites with high SiO_2(71.2-72.8 wt.%),alkali(Na_2 O + K_2 O =8.05-8.44 wt.%), Al_2 O_3(14.4-15.2 wt.%) and Fe_2 O_3~T relative to low MgO contents, yielding Fe_2 O_3~T/MgO ratios of 2.87-3.44, and plotting within the high-K calc-alkaline field on a SiO_2 vs. K_2 O diagram. The aluminum saturation indexes(A/CNK) of the biotite monzogranites range from 1.06 to 1.19, corresponding to weakly to strongly peraluminous. They are enriched in rare earth elements(REE), high field strength elements(HFSEs; Zr,Hf). and large ion lithophile elements(LILEs; Rb, U, Th). The LREEs are enriched relative to the HREEs,with a distinct negative Eu anomaly in a chondrite-normalized REE diagram. Geochemically, the Xierzi biotite monzogranite is classified as an aluminous A-type granite, with all samples plotting within the A2-type granite field on a Y/Nb vs. Rb/Nb diagram. Zircon ε_(Hf)(t) values and two-stage modal ages of the zircons within the pluton range from +4.80 to +13.65 and from 983 to 418 Ma, respectively, indicating that the primary magma was generated through partial melting of felsic rocks from juvenile ***, these results demonstrate that the Xierzi pluton formed under the post-orogenic extensional setting after arc-continent collision in the middle Permian.

关键词： Linxi area A-type granite Zircon U-Pb dating Extensional tectonic setting Paleo-Asian Ocean Arc-continent collision

In situ cosmogenic ^(10)Be, ^(26)Al, and ^(21)Ne dating in sediments from the Guizhou Plateau, southwest China

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Science China Earth Sciences 2021年第8期64卷 1305-1317页

作者： Ye YANG Yu LIU Yan MA Sheng XU Cong-Qiang LIU shi-jie wang Finlay M.STUART Derek FABEL Institute of Surface-Earth System Science School of Earth System ScienceTianjin UniversityTianjin 300072China Scottish Universities Environmental Research Centre East Kilbride G750QFUK State Key Laboratory of Environmental Geochemistry Institute of GeochemistryChinese Academy of SciencesGuiyang 550081China State Key Laboratory of Earthquake Dynamics Institute of GeologyChina Earthquake AdministrationBeijing 100029China

Landscape evolution is modulated by the regional tectonic uplift,climate change,and river ***,how to distinguish these mechanisms through the research of surface exhumation and fluvial incision remains *** this study,cosmogenic ^(10)Be,^(26)Al,and ^(21)Ne concentrations in quartz from cave deposits,modern river sediments,and bedrocks were measured to constrain the applicability of cosmogenic ^(21)Ne and discuss Quaternary landscape evolution history in the Guizhou Plateau,southeast *** the ^(26)Al-^(10)Be and ^(21)Ne-^(10)Be pairs to distinguish the cosmogenic ^(21)Ne concentration from the excess ^(21)Ne,we found that the nucleogenic ^(21)Ne produced by the U and Th decay in quartz is significant in the samples although there is the possibility of inherited cosmogenic ^(21)*** with previous studies,we suggest that the precise approach for applying the cosmogenic ^(21)Ne could be reached by(1)estimating the contribution from nucleogenic ^(21)Ne,(2)avoiding samples with complex burial histories to exclude inherited cosmogenic ^(21)Ne,and(3)combining the ^(10)Be-^(26)Al-^(21)Ne nuclides method for the Quaternary *** addition,both pre-burial basin denudation rates and burial ages derived from the ^(26)Al-^(10)Be pair were used to determine the different timescale surface denudation rate and fluvial incision rate in relation to previous *** consistency of the different timescales pre-burial basin denudation rate,^(36)Cl surface denudation rate,and modern basin denudation rate indicates that the landscape-scale surface denudation has been likely stabilized since the Quaternary in the Guizhou Plateau *** slightly higher river incision rates than the local surface denudation rate show that the river dynamics may not have reached a steady-state due to the regional tectonic uplift in the Guizhou Plateau.

关键词： Cosmogenic^(10)Be-^(26)Al-^(21)Ne Burial dating Incision rate Landscape evolution Guizhou Plateau

Features of intervertebral disc degeneration in rat's aging process

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2009年第7期10卷 522-527页

作者： Yin-gang ZHANG Zheng-ming SUN Jiang-tao LIU shi-jie wang Feng-ling REN Xiong GUO Department of Orthopaedics the First Affiliated Hospital Medical College of Xi'an Jiaotong University Xi'an 710061 China Key Laboratory of Environment and Genes Related Diseases of Ministry of Education Xi 'an Jiaotong University Xi 'an 710061 China

Objective:The age-related change is important part of degenerative disc disease. However,no appropriate animal model or objective evaluation index is available. This study aimed to investigate the features of intervertebral disc degeneration in aging process of rats. Methods:22-month-old Sprague-Dawley(SD) rats were used as spontaneously occurring intervertebral disc degeneration models and 6-month-old rats as young controls. Expression of collagen types II and X was measured by immunohistochemistry. Degenerations of intervertebral discs were scored according to Miyamoto's method. Numbers and areas of afferent vascular buds were measured. The thicknesses of non-calcified and calcified layers were measured and statistically analyzed. Results:There were less collagen type II expression and more collagen type X expression in the calcified layer of the cartilage endplates and nucleus pulposus in the rats of the aged group than in the young control. There were fewer and smaller afferent vascular buds in the rats of the aged group than in the young control group. The ratio of the non-calcified to the calcified layers in the rats of the aged group significantly decreased,compared with that of the young control group(P<0.01) . Conclusion:Rats can spontaneously establish intervertebral disc age-related degeneration. The expression of collagen types II and X,numbers and areas of afferent vascular buds,the ratio of the non-calcified to the calcified layers,and water and glycosaminoglycan contents in the nucleus pulposus are sensitive indexes of intervertebral disc degeneration.

关键词： Intervertebral disc Degeneration Afferent vascular bud Calcified layer Aged

An Organic Small Molecule as a Solid Additive in Non-Fullerene Organic Solar Cells with Improved Efficiency and Operational Stability

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Chinese Journal of Polymer Science 2023年第2期41卷 194-201页

作者： Yi-Nuo Yang Xiao-Ming Li shi-jie wang Xiao-Peng Duan Yun-Hao Cai Xiao-Bo Sun Dong-Hui Wei Wei Ma Yan-Ming Sun School of Chemistry Beihang UniversityBeijing100191China State Key Laboratory for Mechanical Behavior of Materials Xi’an Jiaotong UniversityXi’an710049China The College of Chemistry and Molecular Engineering Zhengzhou UniversityZhengzhou450001China

The use of additive is an effective approach to optimize the active layer morphology and improve the power conversion efficiency(PCE)of organic solar cells(OSCs).However,residual solvent additives always lead to undesirably compromise the stability of *** this work,an organic small molecule BBT-Cl was designed and used as a novel solid additive to partly replace solvent additive to fabricate highperformance *** synergistic effect of the dual additives on the optical property,morphology and photovoltaic characteristics of the PM6:Y6 based non-fullerene OSCs have been systematically *** introduction of BBT-Cl could effectively enhance the crystallinity of the blend and promote charge extraction and ***,the OSCs processed by the dual additives exhibit a high PCE of 17.73%,which is obviously higher than OSCs with CN additive(16.48%).Meanwhile,BBT-Cl based dual additives treatment has also been successfully introduced into another two non-fullerene OSCs to verify its general ***,20%PCE aging is significantly prolonged from 720 min to 2880 min for the devices proceeded with the dual *** work highlights the great potential of solid additive in the fabrication of efficient OSCs with excellent stability.

关键词： Organic solid additive Morphology Dual additives Organic solar cells Operational stability

Intensify standardized therapy for esophageal and stomach cancer in tumor hospitals

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World Journal of Gastroenterology 2001年第1期7卷 80-82页

作者： shi jie wang Deng Gui Wen Jing Zhang Xin Man Hui Liu Fourth Affiliated Hospital of Hebei Medical University, shijiazhuang 050011, Hebei Province, China Hebei Tumor Hospital 5 Jiankanglu Shijiazhuang 050011 Hebei Province China.

INTRODUCTIONCancer treatment situation in tumor hospitals inChina has its own unique characteristics which arenot found in other parts of the world. Because ofthe huge population and high incidence rates ofesophageal ... 详细信息

关键词： Antineoplastic Agents Antineoplastic Protocols China Combined Modality Therapy Esophageal Neoplasms Hospital Mortality Humans Oncology Service, Hospital administration numerical data Program Evaluation Radiotherapy Research Support, Non-U.S. Gov't Stomach Neoplasms Survival Rate

Formal Analysis on an Extended Security Model for Database Systems

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Wuhan University Journal of Natural Sciences 2008年第5期13卷 519-522页

作者： ZHU Hong ZHU Yi LI Chenyang shi jie FU Ge wang Yuanzhen Database and Multimedia Technology Research Institute Huazhong University of Science and Technology Wuhan 430074Hubei China

In order to develop highly secure database systems to meet the requirements for class B2, the BLP （Bell-LaPudula） model is extended according to the features of database systems. A method for verifying security model for database systems is pro- posed. According to this method, an analysis by using Coq proof assistant to ensure the correctness and security of the extended model is introduced. Our formal security model has been verified secure. This work demonstrates that our verification method is effective and sufficient.

关键词： Bell-LaPudula (BLP) model security model Coq integrity constraints