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Computing Persistent Homology by Spanning Trees and Critical Simplices

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Research 2024年第2期2023卷 519-527页

作者： Dinghua shi Zhifeng chen Chuang Ma Guanrong chen Department of Mathematics Cllege of ScienceShanghai UniversityShanghaiChina School of Big data Fuzhou University of International Studies and TradeFuzhouChina Department of data Science and Big data Technology School of InternetAnhui UniversityHefeiChina Department of Electrical Engineering City University of Hong KongHong KongChina

Topological data analysis can extract effective information from higher-dimensional *** mathematical basis is persistent *** persistent homology can calculate topological features at different spatiotemporal scales of the dataset,that is,establishing the integrated taxonomic relation among points,lines,and ***,the simplicial network composed of all-order simplices in a simplicial complex is *** the sequence of nested simplicial subnetworks can be regarded as a discrete Morse function from the simplicial network to real values,a method based on the concept of critical simplices can be developed by searching all-order spanning *** this new method,not only the Morse function values with the theoretical minimum number of critical simplices can be obtained,but also the Betti numbers and composition of all-order cavities in the simplicial network can be calculated ***,this method is used to analyze some examples and compared with other methods,showing its effectiveness and feasibility.

关键词： Morse establishing topological

Design and Gait Planning of a Worm-inspired Metameric Robot for Pipe Crawling

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Journal of Bionic Engineering 2024年第3期21卷 1265-1277页

作者： Yu Liu Qingbiao shi Zhen chen Pen-Tung Sah Institute of Micro-Nano Science and Technology Xiamen UniversityXiamen361102China

The earthworm has been attracted much attention in the research and development of biomimetic robots due to their unique locomotion mechanism,compact structure,and small motion *** paper presents a new design and prototype of a worm-inspired metameric robot with a movement pattern similar to that of *** robot consists of multiple telescopic modules connected in series through joint *** telescopic module mimics the contraction and elongation motion modes of the earthworm segments.A kinematic and dynamic analysis is conducted on the telescopic module,and an input torque calculation method is provided to ensure sufficient friction between the robot and the pipe *** gait modes of the prototype robot for straight and turning locomotion are introduced,and these modes are extended to robots constructed by different numbers of telescopic *** addition,a method is proposed to increase the friction between the robot and the pipe wall in the aforementioned gait modes without changing the robot structure,thereby improving the robot’s motion ability in *** theoretical model of gait modes has also been validated through gait *** findings of this paper would provide a useful basis for the design,modeling,and control of future worm inspired robots.

关键词： Bio-inspired robot Spatial linkage mechanism Kinematics model Peristaltic locomotion

Magnetic Fields Reduce Apoptosis by Suppressing Phase Separation of Tau-441

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Research 2024年第1期2023卷 181-197页

作者： Wen-Juan Lin Wen-Pu shi Wan-Yi Ge Liang-Liang chen Wei-Hong Guo Peng Shang da-Chuan Yin Key Laboratory for Space Bioscience and Biotechnology School of Life SciencesNorthwestern Polytechnical University127 Youyixi RoadXi'an 710072ShaanxiPR China

The biological effects of magnetic fields(MFs)have been a controversial ***,in recent years,there has been increasing evidence that MFs do affect biological ***,the physical mechanism remains ***,we show that MFs(16 T)reduce apoptosis in cell lines by inhibiting liquid–liquid phase separation(LLPS)of Tau-441,suggesting that the MF effect on LLPS may be one of the mechanisms for understanding the“mysterious”magnetobiological *** LLPS of Tau-441 occurred in the cytoplasm after induction with *** phase-separated droplets of Tau-441 recruited hexokinase(HK),resulting in a decrease in the amount of free HK in the *** cells,HK and Bax compete to bind to the voltage-dependent anion channel(VdaC I)on the mitochondrial membrane.A decrease in the number of free HK molecules increased the chance of Bax binding to VdaC I,leading to increased Bax-mediated *** the presence of a static MF,LLPS was marked inhibited and HK recruitment was reduced,resulting in an increased probability of HK binding to VdaC I and a decreased probability of Bax binding to VdaC I,thus reducing Bax-mediated *** findings revealed a new physical mechanism for understanding magnetobiological effects from the perspective of *** addition,these results show the potential applications of physical environments,such as MFs in this study,in the treatment of LLPS-related diseases.

关键词： inhibited Apoptosis finding

Removal of a guide-wire sliding into abdominal cavity via transgastric natural orifice transluminal endoscopic surgery: A case report

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World Journal of Clinical Cases 2024年第3期12卷 596-600页

作者： shi-Ju chen da-Ya Zhang Yan-Ting Lv Fei-Hu Bai Graduate School Hainan Medical UniversityHaikou 571199Hainan ProvinceChina Department of Gastroenterology The Second Affiliated Hospital of Hainan Medical University570216 HaikouHainan ProvinceChina Department of Gastroenterology Clinical Medical Center of Hainan ProvinceHaikou 570216Hainan ProvinceChina

BACKGROUND Guidewire slippage into the peritoneal cavity during clinical operations is extremely ***,this paper aims to report a successful case of guidewire removal using transgastric natural orifice transluminal endoscopic surgery(NOTES).The goal is to enhance physicians'understanding of the management plan for this unique scenario and provide a valuable reference for clinical *** SUMMARY A 64-year-old man presented with abdominal distension and was diagnosed with cirrhosis combined with massive *** proceed with treatment,the patient underwent ultrasound-guided peritoneal puncture and underwent catheterization and ***,a 0.035-inch guidewire slipped into the abdominal cavity during the *** a comprehensive evaluation and consultation by a multidisciplinary team,the guidewire was successfully removed using *** This case highlights the potential consideration of transgastric NOTES removal when encountering a foreign body,such as a guidewire,within the abdominal cavity.

关键词： Guidewire Abdominal cavity Natural orifice transluminal endoscopic surgery Cirrhosis Massive ascites Case report

Simultaneous Bulk-and Surface-initiated Living Polymerization Studied with a Heterogeneous Stochastic Reaction Model

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Chinese Journal of Polymer Science 2024年第3期42卷 364-372,I0008页

作者： Jia-Shu Ma Zhi-Ning Huang Jia-Hao Li Bang-Ping Jiang Yan-da Liao shi-chen Ji Xing-Can Shen State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources(Ministry of Education of China)School of Chemistry and Pharmaceutical SciencesGuangxi Normal UniversityGuilin 541004China School of Computer Science and Engineering&School of Software Guangxi Normal UniversityGuilin 541004China

To better characterize the properties of surface-initiated polymers, simultaneous bulk-and surface-initiated polymerizations are usually carried out by assuming that the properties of the surface-initiated polymers resemble those of the bulk-initiated polymers. Through a Monte Carlo simulation using a heterogeneous stochastic reaction model, it was discovered that the bulk-initiated polymers exhibit a higher molecular weight and a lower dispersity than the corresponding surface-initiated polymers, which indicates that the equivalent assumption is invalid. Furthermore, the molecular weight distributions of the two types of polymers are also different, suggesting different polymerization mechanisms. The results can be simply explained by the heterogeneous distributions of reactants in the system. This study is helpful to better understand surface-initiated polymerization.

关键词： Surface-initiated polymerization Polymer brush Stochastic reaction model Heterogeneous polymerization Simultaneous polymerization

Preoperative laser reduces silicone oil use in primary diabetic vitrectomy

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International Journal of Ophthalmology(English edition) 2022年第4期15卷 591-597页

作者： Wen-Bin Zheng Xiao-Hu Ding Kun-Bei Lai Ji-Zhu Li Yu-Qing Wu Yuan Ma Zi-Ye chen shi-da chen Sai-Nan Xiao Bing-Qian Liu Ying Lin Tao Li State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangdong Provincial Key Laboratory of Ophthalmology and Visual ScienceGuangdong Provincial Clinical Research Center for Ocular DiseasesGuangzhou 510060Guangdong ProvinceChina

AIM: To identify the predictive factors and laser photocoagulation associated with the use of silicone oil as endotamponade during primary diabetic vitrectomy. METHODS: The medical and surgical records of 690 patients(798 eyes) who underwent primary diabetic vitrectomy at a tertiary eye hospital in China from January 2018 to December 2018 were reviewed in this retrospective cohort study. The patients’ baseline characteristics and preoperative treatments were recorded. The binary Logistic regression model was used to evaluate the risk factors for the use of silicone oil as endotamponade agent during primary vitrectomy for proliferative diabetic retinopathy(PDR)-related ***: Among 690 patients with mean age of 52.1±10.5 y(range: 18-85 y), 299/690(43.3%) were female. The 31.6% of the eyes received preoperative laser treatment, and 72.4% of the eyes received preoperative anti-VEGF adjuvant therapy. Non-clearing vitreous haemorrhage(VH) alone or combined with retinal detachment was the main surgical indication(89.5%) for primary vitrectomy. Silicone oil was used as endotamponade in 313(39.2%) eyes. Lack of preoperative laser treatment [odds ratio(OR) 0.66, 95% confidence interval(CI): 0.48-0.92;P=0.015] and older age(OR 0.96, 95%CI: 0.95-0.98;P<0.001) were predictors of silicone oil tamponade during primary vitrectomy for PDR. CONCLUSION: The lack of preoperative laser treatment is a significant predictor of silicone oil tamponade during primary vitrectomy for PDR. However, the severity of PDR relevant to silicone oil use should be further evaluated.

关键词： proliferative diabetic retinopathy vitrectomy laser photocoagulation silicone oil tamponade predictive factors

NSNO:Neumann Series Neural Operator for Solving Helmholtz Equations in Inhomogeneous Medium

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Journal of Systems Science & Complexity 2024年第2期37卷 413-440页

作者： chen Fukai LIU Ziyang LIN Guochang chen Junqing shi Zuoqiang Department of Mathematical Sciences Tsinghua UniversityBeijing 100084China Yau Mathematical Sciences Center Tsinghua UniversityBeijing 100084China Yanqi Lake Beijing Institute of Mathematical Sciences and Applications Beijing 101408China

In this paper,the authors propose Neumann series neural operator(NSNO)to learn the solution operator of Helmholtz equation from inhomogeneity coefficients and source terms to *** equation is a crucial partial differential equation(PDE)with applications in various scientific and engineering ***,efficient solver of Helmholtz equation is still a big challenge especially in the case of high ***,deep learning has shown great potential in solving PDEs especially in learning solution *** by Neumann series in Helmholtz equation,the authors design a novel network architecture in which U-Net is embedded inside to capture the multiscale *** experiments show that the proposed NSNO significantly outperforms the state-of-the-art FNO with at least 60%lower relative L^(2)-error,especially in the large wavenumber case,and has 50%lower computational cost and less data ***,NSNO can be used as the surrogate model in inverse scattering *** tests show that NSNO is able to give comparable results with traditional finite difference forward solver while the computational cost is reduced tremendously.

关键词： Helmholtz equation inverse problem neumann series neural network solution operator

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Control of highly pathogenic avian influenza through vaccination

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Journal of Integrative Agriculture 2024年第5期23卷 1447-1453页

作者： Xianying Zeng Jianzhong shi Hualan chen State Key Laboratory for Animal Disease Control and Prevention Harbin Veterinary Research InstituteChinese Academy of Agricultural SciencesHarbin150069China

The stamping-out strategy has been used to control highly pathogenic avian influenza viruses in many countries,driven by the belief that vaccination would not be successful against such viruses and fears that avian influenza virus in vaccinated birds would evolve more rapidly and pose a greater risk to *** this review,we summarize the successes in controlling highly pathogenic avian influenza in China and make suggestions regarding the requirements for vaccine selection and *** addition,we present evidence that vaccination of poultry not only eliminates human infection with avian influenza virus,but also significantly reduces and abolishes some harmful characteristics of avian influenza virus.

关键词： avian influenza control highly pathogenic vaccination

Experimental Investigation of the Operating Characteristics of a Pulsating Heat Pipe with Ultra-Pure Water and Micro Encapsulated Phase Change Material Suspension

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Journal of Thermal Science 2024年第2期33卷 457-468页

作者： shi Weixiu SU Xiaoyang chen Hongdi PAN Lisheng Beijing Engineering Research Center of Sustainable Energy and Buildings Beijing University of Civil Engineering and ArchitectureBeijing100044China School of Environment and Energy Engineering Beijing University of Civil Engineering and ArchitectureBeijing100044China State Key Laboratory of High Temperature Gas Dynamics Institute of MechanicsChinese Academy of SciencesBeijing100190China

The specific heat capacity of working fluid is an important influence factor on heat transfer characteristic of the pulsating heat pipe(PHP).Due to the relatively large specific heat capacity of micro encapsulated phase change material(MEPCM) suspension,a heat transfer performance experimental facility of the PHP was *** heat transfer characteristic with MEPCM suspension of different mass concentrations(0.5% and 1.0%) and ultra-pure water were compared *** was found that when the PHP uses MEPCM suspension as its working fluid,operating stability is impoverished under lower heating power and the operating stability is better under higher heating *** the inclination angle of 90°,the temperature at heating side decreases compared to ultra-pure water and the temperature at heating side decreases with the raising of MEPCM suspension mass *** heat transfer characteristic of the PHP is positively correlated with the inclination angle and the 90° is *** unfavorable effect of the inclination angle decreases with heating power *** the inclination angle is 90°,the PHP with MEPCM suspension at 1.0% of mass concentration has the lowest thermal transfer resistance and followed by ultra-pure water and MEPCM suspension at 0.5% of mass concentration has the highest thermal transfer *** the inclination angles are 60° and30°,the effect of gravity on the flow direction is reduced to 86.6% and 50% of that on the inclination angle of 90°,respectively,and the promoting effect of gravity on the working fluid is further weakened as the inclination angle further *** to the high viscosity of MEPCM suspension,the PHP with ultra-pure water has the lowest heat transfer *** the inclination angles is 60°,the thermal resistance with MEPCM suspension at0.5% of the mass concentration is lower than that at 1.0% at the heating power below 230 *** thermal resistance of MEPCM suspension tends to be simila

关键词： pulsating heat pipe(PHP) micro encapsulated phase change material(MEPCM) heat transfer characteristic inclination angle