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具有可生物降解、细胞相容、抗菌及生物膜控制的壳聚糖磺基甜菜碱衍生物薄膜生物材料的研究

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Engineering 2024年第4期35卷 95-103页

作者： Maoli Yin Yingfeng Wang xuehong Ren Tung-shi Huang School of Textile and Garment Anhui Polytechnic UniversityWuhu 241000China State Key Laboratory of New Textile Materials and Advanced Processing Technologies&Key Laboratory of Textile Fiber and Products Ministry of Education&Hubei International Scientific and Technological Cooperation Base of Intelligent Textile Materials and ApplicationSchool of Textile Science and EngineeringWuhan Textile UniversityWuhan 430200China Department of Poultry Science Auburn UniversityAuburnAL 36849USA

The purpose of this research was to develop a chitosan sulfobetaine(CS-SNCC)film via the solutioncasting method as a biodegradable antibacterial material for biomedical *** and monochloro-triazine sulfobetaine were used as the raw materials for CS-SNCC preparation,and Fourier-transform infrared(FTIR),ultraviolet–visible(UV-Vis),energy-dispersive X-ray(EDX),and Xray photoelectron spectroscopy(XPS)spectra were used to characterize and analyze the structure of the synthesized ***,the swelling property,thermal stability,biodegradability,cytocompatibility,and antibacterial properties of the CS-SNCC film were comprehensively investigated and compared with those of the chitosan *** results for the film’s enzymatic biodegradation behavior show that the CS-SNCC film undergoes a weight loss of 45.54%after 21 days of *** addition,the CS-SNCC film effectively resists bacterial adhesion,prevents the formation of bacteria biofilms,and exhibits high antibacterial activity,with inactivation rates of 93.43%for Escherichia coli and 91.00%for Staphylococcus ***,the CS-SNCC film shows good cellular activity and cytocompatibility according to the cytotoxicity ***,the prepared biodegradable,cytocompatible,antibacterial,and biofilm-controlling CS-SNCC film has potential for biomedical applications.

关键词： Chitosan Sulfobetaine Antibacterial Biofilm-controlling Film

The Analysis on Item-group Competition Olympic Gold Athlete＇ s Success Factor in China

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International English Education Research 2014年第2期 25-28页

作者： Daling shi xuehong Wang Yiliang Sun Jie Zhang Bo Sun Department of Physical Education Huazhong University of Science and Technology Wuhan Hubei China

Skills leading class project including the backlash against, the nets of combat. To compete against, 3 groups against the crowd at the Asian games and the Olympic Games. The gold medal up a significant portion of the distribution, fighting against sex and the nets to resistance is the advantage of China＇s competitive sports items. With modern training development, in today＇s big games is confrontational project on athletes. Fitness put forward higher request, our country adversarial program in athletes. Physically and foreign athletes, there are still some difference, need to roll out. For this, this paper, from the perspective of comparative study, tries to combat fight, the nets against, physical stamina training to compete against the comparative study. The characteristics of the dialysis physical stamina training, in order to arrange different scientific against body training and promote training methods and means to provide optimization.

关键词： Item-group Competition Olympic Success Factor

对高职类钢铁冶金专业课程教材编写的几点建议

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中国冶金教育 2004年第1期9卷 63-65页

作者：史学红山西工程职业技术学院

近年来,我国高等职业教育事业迅速发展,已成为高等教育的一个重要组成部分,但也面临着许多问题和困难.就钢铁冶金专业而言,专业课教材目前仍是空白.在此我们想结合参加中等职业学校钢铁冶金专业课程教材编写的体会和多年来在中专、高职... 详细信息

近年来,我国高等职业教育事业迅速发展,已成为高等教育的一个重要组成部分,但也面临着许多问题和困难.就钢铁冶金专业而言,专业课教材目前仍是空白.在此我们想结合参加中等职业学校钢铁冶金专业课程教材编写的体会和多年来在中专、高职教学实践中的经验及教训,对即将编写的高职类钢铁冶金专业课程教材提出几点建议.

关键词：高等职业教育钢铁冶金专业教材编写

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新课改背景下如何在英语教学中渗透德育

家长 2020年第23期 109-110页

作者：施学红宁夏回族自治区永宁县第三中学

在新课改的大背景下,学科教学要与德育相融合。英语学科是初中重要的科目之一,英语教学承担着重要的德育工作,在学生的素质教育与发展过程中起着非常重要的作用。由此可见,在英语教学过程中有效地融入德育能促进学生全面健康地发展,提... 详细信息

在新课改的大背景下,学科教学要与德育相融合。英语学科是初中重要的科目之一,英语教学承担着重要的德育工作,在学生的素质教育与发展过程中起着非常重要的作用。由此可见,在英语教学过程中有效地融入德育能促进学生全面健康地发展,提升学生的素质。

关键词：英语教学德育融合全面发展

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模糊控制在导弹倾斜稳定系统中的应用

北京理工大学学报 1999年第2期19卷 186-189页

作者：史雪虹康景利董巍全国庆北京理工大学机电控制工程系

目的研究模糊控制在制导中的应用．方法采用一种改进的模糊控制方法，设计远程反坦克导弹的倾斜稳定系统；通过仿真试验研究模糊控制方法对远程反坦克导弹倾斜通道的控制效果．结果在国内首次将模糊控制应用于非线性时变的反坦克导弹的... 详细信息

目的研究模糊控制在制导中的应用．方法采用一种改进的模糊控制方法，设计远程反坦克导弹的倾斜稳定系统；通过仿真试验研究模糊控制方法对远程反坦克导弹倾斜通道的控制效果．结果在国内首次将模糊控制应用于非线性时变的反坦克导弹的倾斜稳定，达到了很好的控制效果．稳定精度高，动态过程短，对系统参数和结构不确定性具有很好的适应性和鲁棒性．结论本文采用输入论域无“零”档的方法，解决了模糊控制应用于倾斜稳定系统的稳定性问题．该研究结果可应用于相当广泛的一类飞行器的稳定系统中和其它稳定系统中．

关键词：模糊控制倾斜稳定系统导弹制导反坦克导弹

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“互联网+”体验式初中英语教学模式探究

家长 2020年第20期 59-59页

作者：施学红宁夏回族自治区永宁县第三中学

随着信息化时代的到来,"互联网+"体验式教学模式是该时代的一大产物,能够对以往教学模式的缺陷进行弥补,显著提升初中英语课程的教学效果。本文正是基于此,首先分析了"互联网+"在初中英语教学当中的意义,之后总结了"互联网+"体验式初中... 详细信息

随着信息化时代的到来,"互联网+"体验式教学模式是该时代的一大产物,能够对以往教学模式的缺陷进行弥补,显著提升初中英语课程的教学效果。本文正是基于此,首先分析了"互联网+"在初中英语教学当中的意义,之后总结了"互联网+"体验式初中英语教学模式的应用措施,以期指导实践。

关键词： “互联网+” 体验式初中英语教学模式

“互联网+”背景下初中英语阅读能力训练方法探究

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家长 2020年第19期 91-92页

作者：施学红宁夏回族自治区永宁县第三中学

目前,"互联网+"的概念越来越深入,在国内的教育教学领域中,该概念也越来越受到人们的重视。就初中时期英语阅读教学而言,采取"互联网+"能够让教师借助更加多样化的技术手段,将教学资源拓宽,提高英语阅读教学途径的多样化,进而提升学生... 详细信息

目前,"互联网+"的概念越来越深入,在国内的教育教学领域中,该概念也越来越受到人们的重视。就初中时期英语阅读教学而言,采取"互联网+"能够让教师借助更加多样化的技术手段,将教学资源拓宽,提高英语阅读教学途径的多样化,进而提升学生的英语阅读能力。本文正是基于此,首先阐述了"互联网+"在初中英语阅读教学中的意义,之后阐述了"互联网+"背景下初中英语阅读能力的训练方法,以期指导实践。

关键词： “互联网+” 初中英语阅读能力训练方法

Phase II study of novel orally PI3Kα/δinhibitor TQ-B3525 in relapsed and/or refractory follicular lymphoma

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Signal Transduction and Targeted Therapy 2024年第5期9卷 2193-2201页

作者： Huaqing Wang Jifeng Feng Yanyan Liu Zhengzi Qian Da Gao xuehong Ran Hui Zhou Lihong Liu Binghua Wang Meiyun Fang Hebing Zhou Zhenqian Huang shi Tao Zhuowen Chen Liping Su Hang Su Yu Yang Xiaobao Xie Huijing Wu Ping Sun Guoyu Hu Aibin Liang Zhiming Li Department of Oncology Tianjin Union Medical Center of Nankai UniversityTianjin 300121PR China The Institute of Translational Medicine Tianjin Union Medical Center of Nankai UniversityTianjin 300121PR China Department of Medical Oncology Jiangsu Cancer HospitalThe Affiliated Cancer Hospital of Nanjing Medical UniversityNanjing 210009PR China Department of Medical Oncology Henan Cancer HospitalThe Affiliated Cancer Hospital of Zhengzhou UniversityZhengzhou 450003PR China Department of Medical Oncology Tianjin Medical University Cancer Institute and HospitalTianjin 300060PR China Department of Hematology The Affiliated Hospital of Inner Mongolia Medical College010050 HohhotPR China Department of Hematology Weifang People’s HospitalThe First Affiliated Hospital of Weifang Medical University261000 WeifangPR China Department of Lymphoma&Hematology Hunan Cancer HospitalThe Affiliated Cancer Hospital of Xiangya School of MedicineCentral South University410013 ChangshaPR China Department of Hematology The Fourth Hospital of Hebei Medical University and Hebei Tumor Hospital050011 ShijiazhuangPR China Department of Lymphoma Weihai Central Hospital264400 WeihaiPR China Department of Hematology and Rheumatology The Affiliated Zhongshan Hospital of Dalian University116001 DalianPR China Department of Hematology Beijing Luhe Hospital101199 BeijingPR China Department of Hematology The First Affiliated Hospital of Guangzhou Medical University510120 GuangzhouPR China Department of Hematology The First Affiliated Hospital of Hainan Medical College570102 HaikouPR China Department of Hematology The First People’s Hospital of Foshan528000 FoshanPR China Department of Hematology Shanxi Cancer Hospital030013 TaiyuanPR China Department of Lymphoma Senior Department of HematologyThe Fifth Medical Center of Chinese PLA General Hospital100039 BeijingPR China Department of Lymphoma and Head and Neck Cancer Fujian Cancer Hospital350014 FuzhouPR China Department of Hematology The First People’s Hospit

This registration study assessed clinical outcomes of TQ-B3525,the dual phosphatidylinositol-3-kinase(PI3K)α/δinhibitor,in relapsed and/or refractory follicular lymphoma(R/R FL).This phase II study(*** *** March 27,2020)comprised run-in stage and stage 2.R/R FL patients after≥2 lines therapies received oral 20 mg TQ-B3525 once daily in a 28-day cycle until intolerable toxicity or disease *** endpoint was independent review committee(IRC)-assessed objective response rate(ORR).Based on results(ORR,88.0%;duration of response[DOR],11.8 months;progression-free survival[PFS],12.0 months)in 25 patients at run-in stage,second stage study was initiated and included 82 patients for efficacy/safety *** received prior-line(median,3)therapies,with 56.1%refractory to previous last therapies;73.2%experienced POD24 at *** stage 2,ORR was 86.6%(71/82;95%CI,77.3-93.1%),with 28(34.2%)complete *** control rate was 95.1%due to 7(8.5%)stable *** time to response was 1.8 *** 71 responders,median DOR was not reached;18-month DOR rate was 51.6%.with median follow-up of 13.3 months,median PFS was 18.5(95%CI,10.2-not estimable)*** overall survival(OS)was not reached by cutoff date;24-month OS rate was estimated as 86.1%.Response rates and survival data were consistent across all *** 3 or higher treatment-related adverse events were observed in 63(76.8%)cases,with neutropenia(22.0%),hyperglycemia(19.5%),and diarrhea(13.4%)being ***-B3525 showed favorable efficacy and safety for R/R FL patients after≥2 lines prior therapies.

关键词： lymphoma assessed initiated

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减少硅钢冶炼低温喷溅之浅见

山西冶金 1998年第3期21卷 29-30,56页

作者：史学红太原冶金工业学技

针对转炉冶炼硅钢时出现的前期低温喷溅现象,根据废钢熔化的动力学理论并结合现场的原料及操作情况,提出了造成该现象的原因并不单是废钢的装入云量大,更主要的是轻废钢装入量过多的观点,并指出,解决问题的方法是调整好入炉轻、重废钢... 详细信息

针对转炉冶炼硅钢时出现的前期低温喷溅现象,根据废钢熔化的动力学理论并结合现场的原料及操作情况,提出了造成该现象的原因并不单是废钢的装入云量大,更主要的是轻废钢装入量过多的观点,并指出,解决问题的方法是调整好入炉轻、重废钢搭配的比例;另外从现场轻废钢较多的实际出发,提供了削弱前期低温喷溅的两条途径。

关键词：低温喷溅轻废钢重废钢轻、重废钢搭配比例