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A New Cyclohexene Oxide from Uvaria tonkinensis ***

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Chinese Chemical Letters 2003年第11期14卷 1144-1145页

作者： An LIU Zhong Mei ZOU Li Zhen XU shi lin yang Institute of Medicinal Plant Development Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100094

A new compound, subglain B, was isolated from the stems of Uvaria tonkinensis var. subglabra and its structure was identified as 1S, 2R, 3S, 6R-1-benzoyloxymethylene-1,2- dihydroxy-3-benzoyloxy-6-chlorocyclohex-4-ene ... 详细信息

关键词： Uvaria tonkinensis var subglabra subglain B cyclohexene.

Two New Saponins from Lysimachia capillipes Hemsl.

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Journal of Integrative Plant Biology 2005年第10期47卷 1271-1275页

作者： Jing-Kui TIAN Zhong-Mei ZOU Li-Zhen XU shi-lin yang Department of Chinese Medicine Sciences and Engineering Zhejiang University Hangzhou 310027 China Institute of Medicinal Plants Development Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100094 China

To investigate the saponins from whole plants of Lysimachia capilUpes Hemsl., two new saponins, named capilliposide E （1） and capilliposide F （2）, were isolated. The structures of the new saponins were elucidated as 3β, 22α-dihydroxy-16α-acetat-28→ 13-lactone-oleanane-3-O- [β-D-glucopyranosyl- （1 →2）-α-L-arabinpyranoyl]-22-O-β-D-glucopyranoside （1） and 3β, 22α-dihydroxy- 16α-acetat-28→ 13-lactone-oleanane-3-O-{ [β-D-glucopyranosyl-（1→2）-β-D-glucopyranosyl-（1→4）]-α-L-arabinpyranoyl}-22-O-β- D-glucopyranoside （2）. The structures of these compounds were determined by 1D- and 2D-NMR, MS techniques, and chemical methods.

关键词： capilliposide E and F, Lysimachia capillipes triterpene saponin.

New Cytotoxic Saponins from Lysimachia davurica Ledeb.

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Journal of Integrative Plant Biology 2006年第2期48卷 232-235页

作者： Jing-Kui Tian Zhong-Mei Zou Li-Zhen Xu shi-lin yang Department of Chinese Medicine Sciences and Engineering Zhejiang University Hangzhou 310028 China Institute of Medicinal Plants Development Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100094 China

To investigate the saponins from whole plants of Lysimachia davurica Ledeb., two new saponins named davuricoside I （compound 1） and E （compound 2） were isolated. Their chemical structures were elucidated as 3β, 16α, 28, 29-tetrihydroxy-olean-12-en-3-O-β-D-glucopyranosyl-（1→2）-β-D-glucuronopyranoside （compound 1） and 3β, 16α, 29-trihydroxy-13, 28-epoxy-oleanane-3-O-β-D-glucopyranosyl-（1→2）-β-D-glucuronopyranoside （compound 2） on the basis of their one- and two-dimensional nuclear magnetic resonance and mass spectrometry data, and chemical methods. Compound 1 showed significant cytotoxic activity against human A2780 cells.

关键词： davuricoside I and E Lysimachia davurica triterpene saponin.

Two New Polyoxygenated Cyclohexenes from Uvaria kweichowensis

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Chinese Chemical Letters 2005年第10期16卷 1343-1346页

作者： Qiong Ming XU Zhong Mei ZOU Li Zhen XU shi lin yang Institute of Medicinal Plant Development Peking Union Medical College and Chinese Academy of Medicinal Sciences Beijing 100094

Two new polyoxygenated cyclohexenes, kweichowenol A and B were isolated from the leaves of Uvaria kweichowensis and their structures were established on the basis of their spectral data.

关键词： Annonaceae Uvaria kweichowensis leaves cyclohexenes kweichowenol A kweichowenol B.

Research progress of aphid immunity system: Potential effective target for green pest management

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Insect Science 2024年第6期31卷 1662-1674页

作者： Li-Na Sun Jian-Yu Meng Zeng Wang shi-yang lin Jie Shen Shuo Yan Department of Plant Biosecurity College of Plant ProtectionChina Agricultural UniversityBeijingChina Guizhou Tobacco Science Research Institute GuiyangChina Pu'er Agricultural Science Research Institute Pu'erYunnan ProvinceChina

Due to the absence of acquired immunity,insects primarily rely on their innate immune system to resist pathogenic microorganisms and parasitoids in natural *** innate immune system can be classified into cellular immunity and humoral *** immunity is mediated by hemocytes,which perform phagocytosis,aggregation,and encapsulation to fight against invaders,whereas the humoral immunity primarily activates the immune signaling pathways and induces the generation of immune *** studies have revealed that the hemipteran aphids lack some crucial immune genes compared to other insect species,indicating the different immune mechanisms in *** current review summarizes the adverse impacts of pathogenic microorganisms and parasitoids on aphids,introduces the cellular and humoral immune systems in insects,and analyzes the differences between aphids and other insect ***,our review also discussed the existing prospects and challenges in aphid immunity research,and proposed the potential application of immune genes in green pest management.

关键词： cellular immunity green pest management humoral immunity immune gene immune signaling pathway

Covariant Anomaly and Hawking Radiation from Kerr-Newman Black Hole in Dragging Coordinates Frame

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Communications in Theoretical Physics 2008年第8期50卷 541-544页

作者： LIU Xiong-Wei ZENG Xiao-Xiong CHEN shi-Wu lin Kai yang Shu-Zheng Institute of Theoretical Physics China West Normal University Nanchong 637002 China

In the light of Robinson and Wilczek's new idea,and motivated by Banerjee and Kulkarni's simplified method of using only the covariant anomaly to derive Hawking radiation from a black hole,we generally extend the work to Kerr-Newman black hole in dragging coordinates *** is shown that the flows introduced to cancel the anomaly at the event horizon are equal to the corresponding Hawking radiation in dragging coordinates frame,which supports and extends Robinson and Wilczek's opinion.

关键词： Hawking radiation anomaly dragging coordinates frame Kerr-Newman black hole

Two Novel Saponins from Lysimachia capillipes

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Chinese Chemical Letters 2005年第12期16卷 1607-1610页

作者： Jing Kui TIAN Chen XIE Zhong Mei ZOU Li Zhen XU shi lin yang Deptment of Chinese Medicine Science ＆ Engineering Zhejiang University Hangzhou 310028 Institute of Medicinal Plants Development Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100094

Two new saponins named capilliposide C 1 and capilliposide D 2 were isolated from the whole plants of Lysimachia capillipes, their structures were deternuned by 1D and 2D NMR, ESIMS techniques, and chemical *** C show... 详细信息

关键词： Lysimachia capillipes triterpene saponin capilliposide C and D

A new sulfated triterpenoid from the bark of Zygophyllum fabago L.

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Chinese Chemical Letters 2010年第9期21卷 1100-1102页

作者： Yu lin Feng Bin Xie He Ran Li Qiong Ming Xu Xiao Juan Zhang Yue Sheng Wang shi lin yang National Pharmaceutical Engineering Centre for Solid Preparation in Chinese Herbal Medicine Nanchang 330006 China Jiangxi University of Traditional Chinese Medicine Nanchang 330006 China College of Pharmacy. Soochow University. Suzhou 215123. China

A new sulfated triterpenoid,3β,24-dihydroxyurs-20-ene-24-O-sulphonyl-28-oic acid（fabagoin.1） was isolated from the barks of Zygophyllum fabago *** structure was elucidated on the basis of spectroscopic data.

关键词： Zygophyllum fabago L. Sulfated triterpenoid Fabagoin

Differential distribution of fibrovascular proliferative membranes in 25-gauge vitrectomy for proliferative diabetic retinopathy

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International Journal of Ophthalmology(English edition) 2024年第8期17卷 1462-1468页

作者： Nan Lu shi-lin yang Shuo Guo Dong-Ni yang Li Liu Chun-Hui Fan Ying Guo Jian Liu Wei Zhao Department of Ophthalmology the First Hospital of QinhuangdaoQinhuangdao 066000Hebei ProvinceChina School of Control Engineering Northeastern University at QinhuangdaoQinhuangdao 066004Hebei ProvinceChina

AIM:To analyze the distribution of fibrovascular proliferative membranes(FVPMs)in proliferative diabetic retinopathy(PDR)patients that treated with pars plana vitrectomy(PPV),and to evaluate the outcomes ***:This was a retrospective and cross-sectional *** 25-gauge(25-G)PPV cases operated for PDR from May 2018 to April *** to the FVPMs images outlined after operations,subjects were assigned into three groups:arcade type group,juxtapapillary type group,and central type *** patients were followed up for over one *** characteristics,operation-related variables,postoperative parameters and complications were ***:Among 103 eyes recruited,the FVPMs distribution of nasotemporal and inferiosuperioral was significantly different(both P<0.01),with 95(92.23%)FVPMs located in the nasal quadrants,and 74(71.84%)in the *** eyes with a central FVPM required the longest operation time,with silicon oil used in most patients,generally combined with tractional retinal detachment(RD)and rhegmatogenous RD,the worst postoperative bestcorrected visual acuity(BCVA)and the highest rates of recurrent RD(all P<0.05).FVPM type,age of onset diabetes mellitus,preoperative BCVA,and combined with tractional RD and rhegmatogenous RD were significantly associated with BCVA improvement(all P<0.05).Compared with the central type group,the arcade type group had higher rates of BCVA ***:FVPMs are more commonly found in the nasal and inferior mid-peripheral retina in addition to the area of arcade *** 25-G PPV for treating PDR eyes with central FVPM have relatively worse prognosis.

关键词： proliferative diabetic retinopathy fibrovascular proliferative membrane 25-gauge pars plana vitrectomy