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Benzene and lead exposure assessment among occupational bus drivers in Bangkok traffic

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Journal of Environmental Sciences 2004年第1期16卷 61-66页

作者： shing TET LEONG PREECHA LAORTANAKUL Research Lab Supervisor Urban Environmental Engineering and Management ProgramSchool of EnvironmentResource and DevelopmentAsian Institute of TechnologyAffiliated Research Associate G.P.O. Box 4 Klong Luang Pathumthani 12120 Thailand216 Soi Satsana 5 Phya Thai Bangkok 10400 Thailand

Four environmental and biological monitoring sites were strategically established to evaluate benzene and lead exposure assessment at various traffic zones of Bangkok Metropolitan Region(BMR). Biological measurement of 48 non air-conditioned, male bus drivers was carried to study the relationship between individual exposure levels and exposure biomarkers. The study group was further sub-divided into four age groups(16—25, 26—35, 36—45 and 46—55 years old) to monitor the age—related exposure effects. A total of 12 unexposed persons were deliberately chosen as the control group. Measurement of unmetobolized benzene in blood and analysis of urinary tt-Muconic acid urine and urinary creatinine are recommended as biomarkers of benzene exposure. Measurement of lead in blood and urine is also recommended for the biological monitoring of lead exposure. During the monitoring period, benzene and lead levels at Yaowarat Road was C_6H_6: 42.46±3.88 μg/m 3, Pb: 0.29±0.03 μg/m 3 and decreased to C_6H_6: 33.5±1.35 μg/m 3, Pb: 0.13±0.01 μg/m 3 at Phahonyothin Road. Significant difference was established between the nonsmoking exposed group and nonsmoking control group for blood benzene concentrations ( P shed from automobile *** analysis revealed that among the occupational population in the urban sites, the driver groups were found to have the highest risk of benzene and lead exposures derived from automobile emission.

关键词： benzene and lead measurement biomarkers exposure assessment human biomonitoring unleaded gasoline

开源软件库生态治理技术研究综述:二十年进展

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软件学报 2024年第2期35卷 629-674页

作者：王莹伍盈欣高天陈子莺许畅于海张成志东北大学软件学院辽宁沈阳110169 南京大学计算机科学与技术系江苏南京210023 计算机软件新技术国家重点实验室(南京大学) 江苏南京210023 智能工业数据解析与优化教育部重点实验室(东北大学工业智能与系统优化国家级前沿科学中心) 辽宁沈阳110169 香港科技大学计算机科学及工程学系中国香港999077

在“人-机-物”三元融合、泛在计算的时代蓝海下,“开放多变”“需求多样”和“场景复杂”的软件部署和运行环境对开源软件库生态的治理技术提出了更多需求和更高期望.为进一步推动构建可信软件供应链生态,围绕泛在计算模式、打造自主... 详细信息

在“人-机-物”三元融合、泛在计算的时代蓝海下,“开放多变”“需求多样”和“场景复杂”的软件部署和运行环境对开源软件库生态的治理技术提出了更多需求和更高期望.为进一步推动构建可信软件供应链生态,围绕泛在计算模式、打造自主可控的技术体系,聚焦于开源软件库管理生态,收集近20多年来(2001–2023)发表于软件工程领域较高影响力的学术期刊和会议的348篇论文,对开源软件库生态治理技术的研究工作进行梳理.讨论开源软件库生态的建模与分析、演化与维护、质量保证和管理等方面的工作,总结研究现状、问题、挑战与趋势.

关键词：开源软件供应链开源治理软件库生态系统

An environmental approach for used oil management in Asian cities: a Bangkok's experience

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Journal of Environmental Sciences 2003年第6期15卷 734-743页

作者： shing TET LEONG PREECHA LAORTANAKUL Urban Environmental Engineering and Management Program School of Environment Resources and Development Asian Institute of Technology G.P.O. Box 4 Klong Luang Pathumthani 12120 ThailandMailing address: 216 Soi Satsana 5 Phya Thai Bangkok 10400 Thailand

This paper addresses increasing concern about the pollution threat of used oil being illegally dumped and the impact of oil on air pollution and freshwater ecosystems in Asian countries. Used oil is a very serious waste management problem. These results call for management action such as maximising the collection and recovery of used oil. The Thai government recognizes the need to recycle used oil and has been active in encouraging programs to accomplish this goal. Thus unless new approaches and incentives are developed, used oil generation may become an increasing serious problem to our environment. The purpose of this study is to examine the technical and economic feasibility, of recycling used oils. In addition, this paper briefly discusses the problems to be overcome and outlines potential mechanisms for providing the necessary disposal controls in order to maximize the protection to public health and environmental quality from potential hazards posed by used lube oil disposal.

关键词： Bangkok health effects oil pollution recycling used oil collection

cpYFP is a Superoxide Specific Indicator

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cpYFP is a Superoxide Specific Indicator

Effects of SARS-CoV-2 infection on incidence and treatment strategies of hepatocellular carcinoma in people with chronic liver disease

第十七届国际钙结合蛋白与钙在健康和疾病中作用会议

作者： Robert T.Dirksen shey-shing sheu Department of Pharmacology and Physiology University of RochesterSchool of Medicine and DentistryRochesterNY 14642 USA Center for Translational Medicine Thomas Jefferson UniversityPhiladelphiaPA 19107 USA

Reactive oxygen species(ROS) are a class of radical or non-radical oxygen-containing molecules that display high reactivity with lipids,proteins and nucleic *** play important roles in either physiologyl or *** ROS generation leads to apoptotic and necrotic cell death and pathogenesis of a panel of clinically distinct disorders including neurodegeneration, atherosclerosis,***,increasing evidence indicates that homeostatic and physiological levels of ROS are indispensable in regulating diverse cellular processes including ion channel/transporter function,Ca spark production,protein kinase /phosphatase activation,and gene expression.

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World Journal of Hepatology 2024年第2期16卷 211-228页

作者： Lung-Yi Mak Matthew shing Hin Chung Xue Li Francisco Tsz Tsun Lai Eric Yuk Fai Wan Celine Sze Ling Chui Franco Wing Tak Cheng Esther Wai Yin Chan Ching Lung Cheung Ivan Chi Ho Au Xi Xiong Wai-Kay Seto Man-Fung Yuen Carlos King Ho Wong Ian Chi Kei Wong Department of Medicine The University of Hong KongHong KongChina State Key Laboratory of Liver Research The University of Hong KongHong KongChina Department of Pharmacology and Pharmacy The University of Hong KongHong KongChina Laboratory of Data Discovery for Health(D24H) Hong Kong Science and Technology ParkHong KongChina Department of Family Medicine and Primary Care The University of Hong KongHong KongChina School of Nursing The University of Hong KongHong KongChina School of Public Health The University of Hong KongHong KongChina Research Department of Practice and Policy University College LondonLondon WC1E 6BTUnited Kingdom Aston School of Pharmacy Aston UniversityBirmingham B47ETUnited Kingdom

BACKGROUND Chronic liver disease(CLD)was associated with adverse clinical outcomes among people with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)*** To determine the effects of SARS-CoV-2 infection on the incidence and treatment strategy of hepatocellular carcinoma(HCC)among patients with *** A retrospective,territory-wide cohort of CLD patients was identified from an electronic health database in Hong *** with confirmed SARS-CoV-2 infection[coronavirus disease 2019(COVID-19)+CLD]between January 1,2020 and October 25,2022 were identified and matched 1:1 by propensity-score with those without(COVID-19-CLD).Each patient was followed up until death,outcome event,or November 15,*** outcome was incidence of *** outcomes included all-cause mortality,adverse hepatic outcomes,and different treatment strategies to HCC(curative,non-curative treatment,and palliative care).Analyses were further stratified by acute(within 20 d)and post-acute(21 d or beyond)phases of SARS-CoV-2 *** rate ratios(IRRs)were estimated by Poisson regression *** Of 193589 CLD patients(>95%non-cirrhotic)in the cohort,55163 patients with COVID-19+CLD and 55163 patients with COVID-19-CLD were included after 1:1 propensity-score *** 249-d median follow-up,COVID-19+CLD was not associated with increased risk of incident HCC(IRR:1.19,95%CI:0.99-1.42,P=0.06),but higher risks of receiving palliative care for HCC(IRR:1.60,95%CI:1.46-1.75,P<0.001),compared to *** both acute and post-acute phases of infection,COVID-19+CLD were associated with increased risks of allcause mortality(acute:IRR:7.06,95%CI:5.78-8.63,P<0.001;post-acute:IRR:1.24,95%CI:1.14-1.36,P<0.001)and adverse hepatic outcomes(acute:IRR:1.98,95%CI:1.79-2.18,P<0.001;post-acute:IRR:1.24,95%CI:1.13-1.35,P<0.001),compared to *** Although CLD patients with SARS-CoV-2 infection were not associated with increased risk of HCC,they

关键词： SARS-CoV-2 infection Chronic liver disease Long COVID Post-COVID-19 syndrome Cirrhosis Hepatocellular carcinoma

COMPUTING HARMONIC MAPS AND CONFORMAL MAPS ON POINT CLOUDS

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Journal of Computational Mathematics 2023年第5期41卷 879-908页

作者： Tianqi Wu shing-Tung Yau Center of Mathematical Sciences and Applications Harvard UniversityCambridgeMA 02138USA Department of Mathematics Harvard UniversityCambridgeMA 02138USA

We use a narrow-band approach to compute harmonic maps and conformal maps for surfaces embedded in the Euclidean 3-space,using point cloud data *** a surface,or a point cloud approximation,we simply use the standard cubic lattice to approximate itsϵ-*** the harmonic map of the surface can be approximated by discrete harmonic maps on *** conformal map,or the surface uniformization,is achieved by minimizing the Dirichlet energy of the harmonic map while deforming the target surface of constant *** propose algorithms and numerical examples for closed surfaces and topological *** the best of the authors’knowledge,our approach provides the first meshless method for computing harmonic maps and uniformizations of higher genus surfaces.

关键词： harmonic maps conformal maps point clouds

Metrics on complex manifolds

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Science China Mathematics 2010年第3期53卷 565-572页

作者： YAU shing-Tung Department of Mathematics Harvard University Cambridge

In this note we discuss various canonical metrics on complex manifolds. A generalization of the Bergman metric is proposed and the relations of metrics on moduli spaces are commented. At last, we review some existence... 详细信息

关键词： intrinsic metrics generalized Bergman metrics Weil-Petersson metric Strominger system

New results on the geometry of the moduli space of Riemann surfaces

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Science China Mathematics 2008年第4期51卷 632-651页

作者： YAU shing-Tung Center of Mathematical Sciences Zhejiang University

We briefly survey our recent results about the Mumford goodness of several canonical metrics on the moduli spaces of Riemann surfaces, including the Weil-Petersson metric, the Ricci metric, the Perturbed Ricci metric and the Kahler-Einstein metric. We prove the dual Nakano negativity of the Weil-Petersson metric. As applications of these results we deduce certain important results about the L 2-cohomology groups of the logarithmic tangent bundle over the compactified moduli spaces.

关键词： moduli spaces canonical metrics good metrics L 2-cohomology 14D20 14H20 32G13 53C55

Health implication among occupational exposed workers in a chromium alloy factory, Thailand

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Journal of Environmental Sciences 2004年第2期16卷 181-186页

作者： S. Muttamara shing Tet Leong Research Lab Supervisor Urban Environmental Engineering and Management Program School of EnvironmentResources and DevelopmentAsian Institute of Technology G.P.O. Box 4Klong LuangResearch Lab SupervisorUrban Environmental Engineering and Management Program School of EnvironmentResources and DevelopmentAsian Institute of Technology G.P.O. Box 4Klong Luang Pathumthani 12120 ThailandPathumthani 12120 Thailand

This study was conducted to assess the occupational exposure and its health impact on the chromium alloy workers. Environmental and biological monitoring, noise and audiometry measurements were done to evaluate the exposure levels in the factory. A total of 112 non-smoking workers were monitored from July 2001 to August 2002 The results showed that most of the chromium and lead exposures in the factory were below the ACGIH-TWA of 50 μg/m 3 for chromium(Ⅵ) and OSHA-PEL of 50 μg/m 3 for lead. The highest chromium(7 25±0 16 μg/m 3) and lead(14 50±0 29 μg/m 3) concentrations were measured in the vibro room. The results indicated that elevated concentrations of chromium and lead were found in both blood and urine samples especially in those areas which were characterized by poor ventilation. The metal contents in blood and urine samples were significantly correlated with airborne metal concentrations in the factory. The result demonstrated that blood and urinary levels among workers were associated with increasing age and duration of exposure. The background noise level of the factory ranged from 67 6 to 89 2 dBA and was frequently higher than the threshold limit value for noise(90 dBA). According to the audiometric test, the exposed workers showed signs of noise-induced hearing loss. Noise at work continued to be an important factor to hearing loss among exposed workers. In our statistical analysis, a significant hearing loss was established on age effect and year of exposure among the workforce.

关键词： chromium and lead exposure electroplating environmental and biological monitoring audiometry measurement