检索结果-南通市图书馆

Development of the sexually dimorphic nucleus of the preoptic area and the influence of estrogen-like compounds

Neural Regeneration Research 2013年第29期8卷 2763-2774页

作者： Zhen He sherry ann ferguson Li Cui Lazar John Greenfield Merle Gale Paule Division of Neurotoxicology National Center for Toxicological ResearchFood and Drug Administration Department of Neurology University of Arkansas for Medical Sciences

One of the well-defined sexually dimorphic structures in the brain is the sexually dimorphic nucleus, a cluster of cells located in the preoptic area of the hypothalamus. The rodent sexually dimorphic nucleus of the preoptic area can be delineated histologically using conventional Nissl staining or immunohistochemically using calbindin D28K immunoreactivity. There is increasing use of the cal- bindin D28K-delineated neural cluster to define the sexually dimorphic nucleus of the preoptic area in rodents. Several mechanisms are proposed to underlie the processes that contribute to the sexual dimorphism （size difference） of the sexually dimorphic nucleus of the preoptic area. Recent evidence indicates that stem cell activity, including proliferation and migration presumably from the 3^rd ventricle stem cell niche, may play a critical role in the postnatal development of the sexually dimorphic nucleus of the preoptic area and its distinguishing sexually dimorphic feature： a signifi-cantly larger volume in males. Sex hormones and estrogen-like compounds can affect the size of the sexually dimorphic nucleus of the preoptic area. Despite considerable research, it remains un-clear whether estrogen-like compounds and/or sex hormones increase size of the sexually dimor-phic nucleus of the preoptic area via an increase in stem cell activity originating from the 3^rd ventricle stern cell niche.

关键词： neural regeneration review sexual orientation sexual behavior calbindin D28K estrogen-likecompound bisphenol A neural stem cells grants-supported paper neuroregeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Management after flap failure:a narrative review

引用

Plastic and Aesthetic Research 2023年第1期10卷 216-228页

作者： Paige L.Myers sherry Y.Q.Tang Noah H.Saad Adeyiza O.Momoh Section of Plastic Surgery Department of SurgeryUniversity of MichiganAnn ArborMI 48109USA

Autologous free tissue transfer for breast reconstruction is a well-established and reliable form of reconstruction for women undergoing *** surgeries are performed with high rates of success;however,the consequences of flap failure can be devastating to patients and *** reconstruction decision making following flap loss is a uniquely individualized process,based on considerations of safety,patient goals and preferences,as well as the surgeon’s *** first priority following flap failure is to provide thoughtful patient counseling and support through this difficult *** aims of reconstruction salvage after flap loss are to excise unhealthy tissue and restore a breast mound of normal anatomical *** present an algorithm as a possible approach to managing flap *** also review the management of breast reconstruction following free flap failure,including the role of hematologic investigation,anticoagulation recommendations and secondary or tertiary reconstruction with both prosthetic and autologous techniques.

关键词： Microsurgery breast reconstruction flap failure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

From Pariah to Prime Minister:Transformation in the Images of the Indian Community in the Caribbean

引用

Cultural and Religious Studies 2018年第10期6卷 602-611页

作者： sherry-ann Singh University of the West Indies St. AugustineTrinidad and Tobago

Between 1838 and 1917,close to half a million Indians arrived in the Caribbean as labourers under the British scheme of Indian *** completion of their respective periods of indenture,most of these immigrants did not return to India,opting instead to make the Caribbean their *** to a range of very provocative social,economic,and political factors all indubitably tied to British colonial agenda,Indians were unceremoniously implanted into the various colonies where they continued to exist in a pariah like state for the duration of the system of Indian *** termination of the system by 1920,Indians had begun a very checkered journey towards integration in the wider Caribbean *** three Caribbean countries,these journeys culminated in the election of Indian prime ministers and presidents;for many others,they were often marked by the emergence of profoundly eminent Indians who carved out niches for themselves in the social,political,economic,and cultural landscapes of the Caribbean *** communities within nations,the experiences of Indians were marked by varying facets and degrees of growth and development in the locations with substantially large numbers of *** those locations with substantially smaller numbers,the Indian communities were either assimilated as a cultural/ethnic group into the wider social fabrics or,have been struggling to retain their Indian identity as a minority *** objective of this paper is to chart the many trajectories that have emerged with and for Indians in the Caribbean,and to explore the many images and imaginings of Indians in the Caribbean that have been framed along these trajectories;both of and among themselves and from the larger Caribbean framework.

关键词： Hinduism Indian Caribbean Trinidad Transformation Social Religion

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A common genetic mechanism underlying susceptibility to posttraumatic stress disorder

引用

World Journal of Neurology 2013年第3期3卷 14-24页

作者： Zhen He Li Cui Bei He sherry A ferguson Merle G Paule Division of Neurotoxicology National Center for Toxicological Research Food and Drug Administration Jefferson AR 72079-9502 United States Department of Neurology University of Arkansas for Medical Sciences Little Rock AR 72205 United States

We hypothesize that susceptibility to post-traumatic stress disorder(PTSD) may be determined in part by aberrant microtubule-associated protein tau expression in neurons of critical brain structures. The following lines of evidence support this hypothesis. First, epidemiologic data suggest the involvement of genetic factors in the susceptibility to PTSD. Second, the common features of both abnormal tau expression and PTSD include amygdalar and hippocampal atrophy, upregulation of norepinephrine biosynthetic capacity inthe surviving locus coeruleus neurons and dysfunction of N-methyl-D-aspartate-receptors. Finally, our experiments using r Tg4510 mice, a model that over-expresses human mutant tau and develops age-dependent tauopathy, demonstrate that these animals display circling behavior thought to be related to states of anxiety. To detect the potential molecular mechanisms underlying PTSD episodes, laser-assisted/capture microdissection can be used with microarray analysis as an alternative approach to identify changes in gene expression in excitatory and/or inhibitory neurons in critical brain structures(i.e., hippocampus and amygdala) in response to the onset of PTSD.

关键词： Amygdalar damage Anxiety behavior Microarrays Microdissection Microtubule-associated protein tau Post-traumatic stress disorder RNA quality

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

工作场所中的危机传播

引用

武汉理工大学学报（社会科学版） 2012年第3期25卷 350-357页

作者：谢瑞.德弗罗.弗格松亚历山德拉.亨德里克斯柯泽张丽娟渥太华大学传播系西南政法大学全球新闻与传播学院重庆401120

运用危机传播理论及自然主义研究框架,通过对发生于2003年8月14日加拿大安大略省和魁北克省以及美国东北部和中西部等大部分地区遭遇的两国历史上最具深远影响力的电力故障的调查分析,试图收集一家大型联邦机构雇员在电力故障发生后一... 详细信息

运用危机传播理论及自然主义研究框架,通过对发生于2003年8月14日加拿大安大略省和魁北克省以及美国东北部和中西部等大部分地区遭遇的两国历史上最具深远影响力的电力故障的调查分析,试图收集一家大型联邦机构雇员在电力故障发生后一周内所作出的反应信息,并进行分析,发现了该组织机构中危机管理系统存在的问题。

关键词：电力故障危机传播信息传播空隙

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：