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Impact of topical nonsteroidal anti-inflammatory drugs in prevention of macular edema following cataract surgery in diabetic patients

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International Journal of Ophthalmology(english edition) 2018年第4期11卷 616-622页

作者： Ahmed A.Alnagdy Hossam Y.Abouelkheir sherief e.el-khouly Sahar M.Tarshouby Mansoura Ophthalmic Center Faculty of Medicine Mansoura University

AIM： To evaluate the efficacy of prophylactic administration of topical non-steroidal anti-inflammatory drugs（NSAIDs） on macular edema following cataract surgery in diabetic patients, and to compare between types of NSAIDs（ketorolac tromethamine 0.4% and nepafenac 0.1%）. MeTHODS： Group 1（control） received artificial tears substitute as a placebo group, group 2（nepafenac） received topical nepafenac 0.1%, and group 3（ketorolac） received topical ketorolac tromethamine 0.4%. Patients were examined postoperatively after completing one week, one month, two months and three months＇ intervals for evaluating cystoid macular edema（CMe） de.elopment. The main study outcomes were achieving the best corrected visual acuity（BCVA） and change in the central macular thickness（CMT） measured with optical coherence topography（OCT）.ReSULTS： eighty eyes of 76 patients were included in this study. BCVA showed a statistically significant difference at the third month postoperative follow up between the control group and the NSAIDs groups（P=0.04）. There was an increase in the CMT in all cases starting from postoperative first week until third month. CMT showed a statistically significant difference between control group and NSAIDs groups from postoperative first month until third month（P=0.008, 0.027, 0.004）. There was no statistically significant difference between nepafenac and ketorolac groups in BCVA and OCT CMT. CONCLUSION： Prophylactic preoperative and postoperative NSAIDs may have a role in reducing the frequency and severity of CMe in diabetic eyes following cataract surgery.

关键词： diabetes mellitus cataract surgery central macular thickness non-steroidal anti-inflammatory drugs ketorolac nepafenac

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Functional and anatomical evaluation of the effect of nepafenac in prevention of macular edema after phacoemulsification in diabetic patients

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International Journal of Ophthalmology(english edition) 2019年第3期12卷 387-392页

作者： Tharwat Mokbel Sameh Saleh Mona Abdelkader sherief e.el-khouly Waleed Abou Samra Mohamed Mamdouh Mansoura Ophthlmic Center Faculty of Medicine Mansoura University

AIM: To evaluate the effect of prophylactic administration of nepafenac in prevention of macular edema occurring in diabetic patients after phacoemulsification and to investigate the correlation between optical coherence tomography(OCT) foveal thickness and multifocal electroretinogram(MF-eRG) ***: The study included two groups. Group 1 included 50 diabetic patients with senile cataract(50 eyes, 30 females, 20 males, aged 55±7 y) received nepafenac 0.1% eye drop. Group 2 included another 50 diabetic patients with senile cataract(50 eyes, 22 female, 28 males, aged 53.8±8 y) did not receive nepafenac. All patients were followed up for 3 mo postoperatively. OCT and MF-eRG were done preoperative and at 1 wk, 1, 2 and 3 ***: The mean foveal thickness was statistically significantly lower in Group 1. Five eyes in Group 2 de.eloped clinical cystoid macular oedema(CMO)(10%), and no patients in Group 1 de.eloped central macular thickening more than 50 μm. There were insignificant differences in MF-eRG amplitudes and latencies between the two groups except in the five eyes that de.eloped CMO, there statistically significant reduction of MF-eRG amplitude with increase in foveal thickness. CONCLUSION: Perioperative nepafenac reduces the incidence of CMO following uncomplicated phacoemulsification significantly. Nepafenac has no side effects.

关键词： nepafenac macular edema cataract surgery diabetes optical coherence tomography multifocal electroretinogram

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Visual performance after implantation of two types of phakic foldable intraocular lenses for correction of high myopia

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International Journal of Ophthalmology(english edition) 2019年第2期12卷 284-290页

作者： Islam M.Rizk Abd-Almonem A.Al-hessy sherief e.el-khouly Ashraf M.Se.elam Mansoura Ophthalmic Center Faculty of Medicine Mansoura University

AIM: To compare Visian lens(model V4 c) and Artiflex lens regarding quality(contrast sensitivity) and quantity(efficacy, predictability, safety and stability) of vision in correcting high myopia with recording and analysis of complications. MeTHODS: The comparative prospective study included 39 eyes of 23 patients with high myopia, 19 eyes had Visian lens implantation(model V4 c) and 20 eyes had Artiflex lens implantation. The inclusion criteria were high myopia(higher than 6.0 D) and stable refraction(e over one year). Outcomes included assessment of safety and efficacy indices, predictability, stability, contrast sensitivity and analysis of complications at postoperative 1 d, 1 wk and 1, 3, 6 and 12 mo. Selection of the type of phakic intraocular lens for patients was based on surgeons' preferences, which was no specific selection criteria. ReSULTS: After 12 mo of follow up, difference in uncorrected and corrected distant visual acuity(CDVA) between both groups was statistically insignificant(UDVA for VisianV4 c and Artiflex lens were 0.33±0.2 logMAR and 0.37±0.2 logMAR respectively, P=0.59, CDVA for VisianV4 c and Artiflex lens were 0.155±0.1 logMAR and 0.147± 0.1 logMAR respectively, P=0.87). The efficacy index was 1.25 for VisianV4 c lens and 0.8 for Artiflex lens, 78.9% of eyes were within one diopter spherical equivalent in Visian V4 c lens group compared to 70% in the Artiflex lens group. No eye lost lines of CVDA proving a good safety index for both lenses(safety index was 1.67 for VisianV4 c lens and 1.34 for Artiflex lens). Difference in contrast sensitivity between both groups was statistically insignificant(P=0.15, 0.88, 0.27, 0.32 and 0.82 at five spatial frequencies). CONCLUSION: Both Visian ICL V4 c and Artiflex lensesare safe and effective with stable and predictable refraction and they have comparable contrast sensitivity outcomes with no vision threatening complications.

关键词： phakic intraocular lenses implantable collamer Visian V4c lens foldable Artiflex lens

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Launching a paradigm for first and redo-surgery in primary congenital glaucoma: institutional experience

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International Journal of Ophthalmology(english edition) 2019年第2期12卷 226-234页

作者： Tharwat H.Mokbel eman M.el Hefney Sherein M.Hagras Amani e.Badawi Manal A.Kasem Ahmed A.Al Nagdy sherief e.el khouly Walid M.Gaafar Mansoura Ophthalmic Center Faculty of Medicine Mansoura University

AIM: To evaluate the outcome of the initial and the redo-surgeries for primary congenital glaucoma(PCG) correlated to its degree of severity. MeTHODS: A retrospective study involved patients with PCG presented between 2010 and 2018. Medical records were reviewed to assess the degree of the preoperative severity according to the intraocular pressure(IOP), corneal diameter and corneal edema. Success and failure rates were calculated for both first and redo-surgeries at 6 and 12 mo respectively then correlated to the severity of the cases. ReSULTS: Complete records were retrieved for 272 eyes(153 patients) with PCG: 43 eyes were mild, 136 moderate and 93 severe. Combined trabeculotomy and trabeculectomy(CTT) had the highest success rate in moderate(96.4%) and severe cases(59.3%) while trabeculotomy had the highest success rate in mild cases(96.3%). Medical records of 88 eyes(63 patients) with recurrent PCG were analyzed, most with severe presentation(59 eyes). Ahmed glaucoma valve(AGV) was used in 67(76%) eyes and augmented trabeculectomy in 21(24%) eyes. At 12 mo, there was no statistically significant difference between both surgeries in total success rate(P=0.256). For mild cases, success rate was 100% for both surgeries. Severe cases had higher success rates following AGV(87%) than augmented trabeculectomy(20%). Preoperative severity of the disease was an independent factor affecting the failure rate in secondary trabeculectomy but not in AGV. Patients younger than 24 mo had higher probabilities of failure following both redo-surgeries with hazard ratio =1.325 and 0.37 for augmented trabeculectomy and AGV respectively. CONCLUSION: Preoperative assessment of the severity of eyes with PCG helps in the selecting the optimal primary and secondary surgery. For first surgery, trabeculotomy is more effective in mild cases whereas; CTT and augmented subscleral trabeculectomy(SST) are appropriate for moderate and severe cases. AGV proved to be superior to augmented SST in

关键词： Ahmed glaucoma valve augmented trabeculectomy egypt primary congenital glaucoma

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Monitoring the transformation in New Cairo’s urban vitality and the accompanying social and economic phenomena

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Frontiers of Architectural Research 2023年第5期12卷 867-891页

作者： Tamir el-khouly Asmaa eldiasty Basil Kamel Department of Architecture Faculty of EngineeringAin Shams UniversityCairo 11566Egypt Department of Architecture School of Sciences and EngineeringThe American University in CairoCairo 11835Egypt Department of Architecture Faculty of EngineeringHorus UniversityNew Damietta 34517Egypt

Many cities in egypt have been built recently with spatial characteristics that differ structurally from the spatial configuration of the ancient Arab *** is a growing interest in understanding how social and economic phenomena related to the community are transformed in new cities,particularly those that extend from the old city,as is the case with the city of New *** have de.eloped an analytical framework to study the effects of spatial configuration on the pace of growth of the new city and identify its characteristics in terms of phenomena related to movement and the distribution of economic activities,as well as urban vitality.A framework for combining quantitative and qualitative analysis helps in understanding phenomena related to the morphology of the de.elopment of the new *** syntactic analysis,place syntax and field observation,the spatial characteristics of the city of New Cairo were investigated,then compared with Old Cairo to determine which features were enriched in terms of the city’s vitality or what has been lost during the expansion phases,based on the planning concepts that were *** study concluded that changes in the characteristics of the spatial configurations of the new egyptian cities by increasing the flow of vehicular traffic via wide arterial roads do not reflect the requirements of the local community,but instead impede local movement within the city and reduce the integration of its neighbourhoods,turning them into isolated *** greatest impact of this is the way in which the characteristics of society in these cities have been limited,resulting in isolation and a lack of connection with the identity of the place and the customs and traditions of the *** paper presents an analytical framework for evaluating similar cities in terms of the characteristics of this planning configuration,identifying the extent to which the old has been preserved or changed and emphasising the validity of the meth

关键词： Space syntax Naturalmovement Spatial configuration Urban vitality

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Night blindness due to vitamin A deficiency associated with resected adenocarcinoma of the pancreas

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International Journal of Ophthalmology(english edition) 2015年第1期8卷 206-207页

作者： Andreas Kontos Hamzeh Kayhanian Fatima el-khouly Roopinder Gillmore Department of Ophthalmology Royal Free Hospital Department of Oncology Royal Free Hospital

Dear Sir,W e write to present a rare case of night blindness caused by vitamin A deficiency secondary to resected adenocarcinoma of the *** our knowledge this is the first reported case of this association.A 62 year-o... 详细信息

关键词： eRG Night blindness due to vitamin A deficiency associated with resected adenocarcinoma of the pancreas

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Analysis and Control of a Three-Phase Switched Reluctance Wind Generator

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Journal of energy and Power engineering 2013年第3期7卷 545-551页

作者： Hassan Bazzi Ali Oshieba Ahmed Fathy Fahmy el-khouly Department of electrical and electronic engineering School of Engineering Lebanese International University Beirut 146404Lebanon Department of electrical engineering Faculty of Engineering Minoufiya University Shebin EI-Kom 32511 Egypt

This paper deals with various aspects of modeling, simulation, analysis, and control ofa SRG （switched reluctance generator） in different modes of operation. excitation method of such a generator is shortly described. The output power of the SRG is controlled so that it can track the maximum output power of a wind turbine drive applications. Also, the output generator voltage is stabilized under either load or wind speed variations. Basic operational characteristics of a three-phase 6/4 SRG are de.eloped through experimental observation. Meanwhile, the real-time operation was implemented in a DSP （digital signal processor） environment. The simulation of the complete system model has been obtained using the Matlab/Simulink software. A good agreement between experimental and simulation results has been observed which supports the validity of the proposed analysis.

关键词： Switched reluctance generator wind power generation variable speed drives.

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A Novel Triphenylamine-substituted Polyfluorene-C60 Triad:Synthesis and Photoinduced electron Transfer Process

A Novel Triphenylamine-substituted Polyfluorene-C60 Triad:Sy...

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2007年全国高分子学术论文报告会

作者：庄小东陈彧 Mohamed e．eI-khouly Osamu Ito 华东理工大学化学与分子工程学院教育部“结构可控先进功能材料及其制备技术”重点实验室 Institute of Multidisciplinary Research for Advanced Materials Tohoku UniversityKatahira 2-1-1Sendai 980-8577Japan

＜正＞Ultrafast photoinduced electron（charge）transfer from the conjugated polymers,which are a subject of extensive academic and commercial interest for use as the active materials in solar cells,photodiodes, and li... 详细信息

关键词：光诱导电荷转移高分子合成 C60

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推-拉型聚芴光电功能材料的合成、光诱导电荷转移及其分子记忆性能

推-拉型聚芴光电功能材料的合成、光诱导电荷转移及其分子记忆性能

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全国第八届有机固体电子过程暨华人有机光电功能材料学术讨论会

作者：庄小东陈彧 Mohamed e.eI-khouly Ling Qidan Shunichi Fukuzumi Kand entang 教育部结构可控先进功能材料及其制备重点实验室华东理工大学化学与分子工程学院 Department of Material and Life Science Graduate School of EngineeringOsaka University Department of Chemical and Biomolecular engineering National University of Singapore

设计和制备具有光诱导电荷转移特征的推-拉型高分子光电功能材料,探索材料在光电转换和分子电子器件中的应用是目前国际上研究热点之一。我们合成了一种新型分散红终端的推拉型高分子光电功能材料DR1-PDPAF-DR1(图1),该材料具有很高的...

设计和制备具有光诱导电荷转移特征的推-拉型高分子光电功能材料,探索材料在光电转换和分子电子器件中的应用是目前国际上研究热点之一。我们合成了一种新型分散红终端的推拉型高分子光电功能材料DR1-PDPAF-DR1(图1),该材料具有很高的热稳定性、优异的空穴传输性能、高效的电荷分离过

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