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Advances in endobariatrics:past,present,and future

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Gastroenterology Report 2023年第1期11卷 140-150页

作者： Abhishek shenoy Allison R.Schulman Division of Gastroenterology and Hepatology University of MichiganMichigan MedicineAnn ArborMIUSA Department of Surgery University of MichiganMichigan MedicineAnn ArborMIUSA

the obesity epidemic in the USA and worldwide is well documented and continues to *** metabolic and bariatric therapies may offer a less invasive approach than surgical *** article will review advances in endobariatrics over the last several decades,addressing the past and current state of bariatric and metabolic *** and Drug Administration-cleared devices and interventions currently under investigation are described including gastric devices,gastric remodeling procedures,small-bowel devices,duodenal ablation,as well as procedures to address weight regain after bariatric *** studies evaluating gastric and duodenal combination therapy,adjunctive pharmacotherapy,as well as individualized precision-health algorithms are underway.

关键词： metabolic devices endoscopic sleeve gastroplasty obesity endobariatrics bariatric therapy

Evaluation of antiinflammatory activity of tephrosia purpurea in rats

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Asian Pacific Journal of tropical Medicine 2010年第3期3卷 193-195页

作者： shenoy Smita Shwetha K Prabhu K Maradi R Bairy KL Shanbhag t Department of Pharmacology Kasturba Medical CollegeManipal University Department of Biochemistry Kasturba Medical CollegeManipal University

Objective:to evaluate the antiinflammatory activity of orally administered ethanolic extract of tephrosia purpurea in acute and subacute inflammation in ***:An ethanolic extract of tephrosia purpurea was *** induced paw edema and cotton pellet granuloma were the models for acute and subacute inflammation *** groups of rats in each model were treated orally with 2%gum acacia,100 mg /kg of aspirin,500 mg/kg and 1 000 mg/kg of ethanolic extract of tephrosia purpurea *** carrageenan induced paw edema model, subplantar injection of 1%carrageenan was made into the hind paw of the rats sixty minutes after the administration of the respective *** paw volume was measured immediately after injection of carrageenan,at 3 hours and at 6 *** percentage inhibition of edema was *** the cotton pellet granuloma model,animals were administered drugs for six days after placing cotton pellets in the axilla on each *** the 7th day,dry weight of granuloma was ***:the rats treated with tephrosia purpurea did not exhibit any significant decrease in paw volume and serum ceruloplasmin levels as compared to the control and aspirin treated groups in the acute inflammation model;while,there was a significant(P < 0.01) decrease in the weight of granuloma in tephrosia purpurea and aspirin treated groups as compared to control in subacute ***:the ethanolic extract of orally administered tephrosia purpurea shows significant antiinflammatory effect in subacute inflammation but not in acute inflammation in rats.

关键词： tephrosia purpurea Antiinflammatory activity Oral Acute inflammation Subacute inflammation

Drop formation at nozzles submerged in quiescent continuous phase： an experimental study with tBP-dodecane and nitric acid system

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Nuclear Science and techniques 2018年第6期29卷 110-118页

作者： Amitava Roy MayurDarekar K. K. Singh K. t. shenoy R. B. Grover Homi Bhabha National Institute Anushaktinagar Mumbai 400094 India Chemical Engineering Division Bhabha Atomic Research Centre Mumbai 400085 India

Solvent extraction is an important process in the nuclear fuel cycle. tributyl phosphate(tBP) diluted with dodecane is commonly used as a solvent for extracting heavy metals from nitric acid medium. Studies on hydrodynamics of a single drop, which is the smallest mass transfer entity, are required for better understanding of the complex mass transfer and phase separation phenomena that occur in extraction equipment. In this study, drop formation at nozzles is studied using 30% tBP-dodecane as the dispersed phase and dilute nitric acid as the quiescent continuous phase. Experiments are carried out to determine the drop diameter, jetting velocity, drop detachment height and drop detachment time for various dispersed phase velocities, nozzle diameters(1.91, 3.04, and 4.88 mm), and nitric acid concentrations(0.01, 1, 3 N). Drop formation is captured using high-speed imaging, which enables quantification of drop size, onset of jetting, drop detachment height, and drop detachment time. Experimental data are used to propose correlations for predicting drop diameter and minimum jetting velocity. the correlations are found to be very accurate with average absolute relative errors being 5.23 and 2.97%, respectively.

关键词：试验性硝酸静止沉没系统高速度分离现象磷酸盐

A simple single-step approach towards synthesis of nanofluids containing cuboctahedral cuprous oxide particles using glucose reduction

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Frontiers of Materials Science 2018年第1期12卷 74-82页

作者： U. Sandhya shenoy A. Nityananda SHEttY Department of Chemistry National Institute of Technology Karnataka Surathkal Mangalore 575025 Karnataka India Department of Chemistry College of Engineering and Technology Srinivas University Mangalore 574146 India

Enhancement of thermal properties of conventional heat transfer fluids has become one of the important technical challenges. Since nanofluids offer a promising help in this regard, development of simpler and hassle free routes for their synthesis is of utmost importance. Synthesis of nanofluids using a hassle free route with greener chemicals has been reported. the single-step chemical approach reported here overcomes the drawbacks of the two-step procedures in the synthesis of nanofluids. the resulting Newtonian nanofluids prepared contained cuboctahedral particles of cuprous oxide and exhibited a thermal conductivity of 2.852 W- m-1. K-1. Polyvinylpyrro- lidone （PVP） used during the synthesis acted as a stabilizing agent rendering the nanofluid a stability of 9 weeks.

关键词： cuprous oxide nanofluids thermal conductivity viscosity

Anal carcinoma in giant anal condyloma, multidisciplinary approach necessary for optimal outcome:two case reports and review of literature

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World Journal of Gastrointestinal Oncology 2019年第2期11卷 172-180页

作者： Santosh shenoy Murali Nittala Yazen Assaf Department of General and Colorectal Surgery KCVA and University of Missouri at Kansas City

BACKGROUND Anal cancers are caused by human papilloma virus(HPV). Buschke-Lowenstein tumor also known as giant anal condyloma(GCA) is a variant of giant neglected anal tumors arising from warts caused by HPV infection. HPV are a family of double-stranded DNA viruses and primarily cause sexually transmitted disease of the genitalia and oropharyngeal mucosa. these tumors are slow growing;locally destructive large verrucous *** SUMMARY We present a series of two cases with large anal tumors harboring invasive cancers and highlight their presentation and management. tumors with high risk HPV subtypes(HPV 16, 18, 31, 33) may progress into invasive squamous cell carcinoma(SCC). Untreated GCA can attain enormous size and extend into the pelvic organs and bony structures. Some tumors show malignant degeneration into SCC and are often difficult to diagnose given the large size of the *** surgical excision with negative margins is the treatment of choice and necessary to prevent recurrence. this is often not feasible and leaves large surgical wounds with tissue defects with delay in healing and increases postoperative morbidity. Pelvic reconstructive techniques including muscle flaps and grafts are often necessary to close the defects. Human immunodeficiency virus and immunocompromised patients generally do poorly with standard *** A multidisciplinary team of colorectal and plastic surgeons, medical and radiation oncologists along with combination treatment modalities are necessary when malignant transformation occurs in GCA, for optimal outcomes.

关键词： Squamous cell carcinoma of anus Human papilloma virus infection Giant anal condyloma Buschke-Lowenstein tumor Multidisciplinary treatment Case report

Effect of Phyllanthus *** on burn wound in rats

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Asian Pacific Journal of tropical Medicine 2010年第2期3卷 105-108页

作者： tara Shanbhag Arul Amuthan Smita shenoy Sudhakar Department of Pharmacology Kasturba Medical College

Objective:to evaluate the effect of ethanolic extract of Phyllanthus ***(Euphorbiaceae) on experimentally induced burn wound model in rats and to evaluate whether it reverses the wound healing in steroid suppressed ***:two models including burn wound model and dexamethasone suppressed bum wound model were used in the *** formulations of ethanolic extract of Phyllanthus niruri were prepared in gum acacia at 8%and in ointment base at 10%and were administered orally(400 mg/kg) and externally *** parameters studied were the wound contraction and the period of ***:In bum wound model,oral and topical administration of Phyllanthus niruri did not show any significant effects in wound contraction and period of epithelialisation when compared to *** dexamethasone suppressed burn wound model,wound contraction rate was increased significantly by topical(P < 0.001) and oral(P < 0.001) administrations of Phyllanthus niruri by about 47.57%and 26.16% *** administration has shown significant(P < 0.05) enhancement of wound contraction than oral dosage *** depressed epithelialisation period was reversed significanUy by topical(P < 0.0001) and oral(P <0.001) administrations of Phyllanthus niruri by about 32.5%and 21.3%***:Both topical and oral administrations of ethanolic extract of Phyllanthus niruri are found to reverse dexamethasone suppressed burn wound healing.

关键词： Phyllanthus niruri Burn wound Dexamethasone suppressed wound healing Wound contraction Epithelialisation period

Resolving the Colletotrichum siamense species complex using ApMat marker

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Fungal Diversity 2015年第2期71卷 247-264页

作者： Gunjan Sharma Anil Kumar Pinnaka Belle Damodara shenoy Microbial type Culture Collection and Gene Bank CSIR-Institute of Microbial TechnologySector 39-AChandigarh 160036India Biological Oceanography Division CSIR-National Institute of OceanographyDona PaulaGoa 403004India

Colletotrichum gloeosporioides sensu lato has been associated with anthracnose in diverse commercial *** is now established that *** sensu lato comprises 33 phylogenetic species and *** sensu stricto is not a common pathogen of tropical *** this study,we investigated the phylogenetic relationships of 85 Colletotrichum isolates associated with select tropical fruits and flowering plants from *** the ApMat marker analysis,the 85 isolates clustered with 7 known Colletotrichum species(***,***,***,***,***,***,Glomerella cingulata ***)and six novel *** of the novel lineages is described and illustrated in this paper as Colletotrichum communis ***.,while new-host pathogen associations for ***,***,*** and *** are reported from *** of the 85 isolates analysed in this paper,73 isolates clustered within the *** species complex,indicating that *** species complex,not *** sensu stricto,is common on tropical *** comparison with act,cal,gapdh,ItS and tub2 gene markers,we recommend the use of the ApMat marker for accurate identification of cryptic species within the *** species *** believe that the ApMat marker,in combination with one or two similar‘phylogenetically superior’gene markers,is a better candidate for specieslevel classification of fungi that were traditionally identified as‘Colletotrichum gloeosporioides’.

关键词： Apn2/MAt IGS Ascomycota Pathogenicity testing Phylogeny tropical crops

Knowledge,attitude and anxiety pertaining to basic life support and medical emergencies among dental interns in Mangalore City,India

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World Journal of Emergency Medicine 2017年第2期8卷 131-135页

作者： Vinej Somaraj Rekha P shenoy Ganesh shenoy Panchmal Praveen S Jodalli Laxminarayan Sonde Ravichandra Karkal Department of Public Health Dentistry Rajas Dental College&HospitalTirunelveliTamil NaduIndia Department of Public Health Dentistry Yenepoya Dental CollegeMangaloreKarnatakaIndia Department of Psychiatry Yenepoya Medical CollegeMangaloreKarnataka 575018India

BACKGROUND: this cross-sectional study aimed to assess the knowledge, attitude and anxiety pertaining to basic life support(BLS) and medical emergencies among interns in dental colleges of Mangalore city, Karnataka, ***: the study subjects comprised of interns who volunteered from the four dental colleges. the knowledge and attitude of interns were assessed using a 30-item questionnaire prepared based on the Basic Life Support Manual from American Heart Association and the anxiety of interns pertaining to BLS and medical emergencies were assessed using a State-trait Anxiety Inventory(StAI) Questionnaire. Chi-square test was performed on SPSS 21.0(IBM Statistics, 2012) to determine statistically signifi cant differences(Ptween assessed knowledge and ***: Out of 183 interns, 39.89% had below average knowledge. A total of 123(67.21%) reported unavailability of professional training. the majority(180, 98.36%) felt the urgent need of training in basic life support procedures. Assessment of stress showed a total of 27.1% participants to be above highstress level. Comparison of assessed knowledge and stress was found to be insignifi cant(P=0.983).CONCLUSION: there was an evident lack of knowledge pertaining to the management of medical emergencies among the interns. As oral health care providers moving out to the society, a focus should be placed on the training of dental interns with respect to Basic Life Support procedures.

关键词： Basic life support Cardiopulmonary resuscitation Dental interns Medical emergencies State-trait anxiety inventory

Facile solvothermal synthesis of NiFe2O4 nanoparticles for high-performance supercapacitor applications

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Frontiers of Materials Science 2020年第2期14卷 120-132页

作者： Meenaketan SEtHI U.Sandhya shenoy Selvakumar MUtHU D.Krishna BHAt Department of Chemistry National Institute of Technology KarmatakaSurathkalMangalore-575025India Department of Chemistry College of Engineering and TechnologySrinivas UniversityMukka-574146KarmatakaIndia Department of Chemistry Manipal Institute of TechnologyManipal-576104KarnatakaIndia

We report a green and facile approach for the synthesis of NiFe2O4(NF)nanoparticles with good *** prepared materials are studied by various techniques in order to know their phase structure,crystallinity,morphology and elemental *** BEt analysis revealed a high surface area of 80.0 m^2·g^-1 for NF possessing a high pore volume of 0.54 cm^3·g^-1,also contributing to the amelioration of the electrochemical *** NF sample is studied for its application in supercapacitors in an aqueous 2 mol·L^-1 KOH *** properties are studied both in the three-electrode method and in a symmetrical supercapacitor *** show a high specific capacitance of 478.0 F·g^-1 from the CV curve at an applied scan rate of 5 mV·s^-1 and 368.0 F·g^-1 from the GCD analysis at a current density of 1A·g^-1 for the NF ***,the material exhibited an 88%retention of its specific capacitance after continuous 10000 cycles at a higher applied current density of8 A·g^-*** encouraging properties of NF nanoparticles suggest the practical applicability in high-performance supercapacitors.

关键词： NiFe2O4 nanoparticle solvothermal method BEt surface area specific capacitance supercapacitor