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Accretionary complex:Geological records from oceanic subduction to continental deep subduction

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Science China Earth Sciences 2020年第12期63卷 1868-1883页

作者： Jianbo zhou Key Laboratory for Evolution of Past Life and Environment in Northeast Asia(Jilin University) Ministry of EducationChangchun130026China College of Earth Sciences Jilin UniversityChangchun130061China

Accretionary complex was usually formed by offscraping of the subducting crustal material over the trench and thus often referred to as subduction zone mé*** structure,composition and forming process of accretionary wedges can provide important insights into the evolution history of ocean basin,ocean-continent material cycle,continental accretion and thus contribute to understanding of the origin of plates and the growth of *** complex is characterized by a block-in-matrix structure associated with imbricate thrusts and isoclinal folds,diversified metamorphic types and intense water-rock interactions,which are distinct to the traditional *** the proposal of the concept of accretionary wedge over a hundred years ago,great progress has been made in a variety of research focuses,such as the identification of the distribution of accretionary complexes,their compositions and formation mechanisms,the affinities of the matrix and igneous rocks,the recognition of the Ocean Plate Stratigraphy(OPS),the reconstruction of oceanic basin,the dynamic background of the tectonic evolution,the relationship between subduction zone and orogenic belt and,in particular,the accretionary complexes in continental subduction *** studies have significantly improved our understanding of the plate tectonic *** remain in the identification of ancient accretionary complexes,the detailed analysis of accretionary complex zones,the accretion characteristics during continental collision,and the geochemical tracing of water-rock interaction during the *** contains representative orogenic belts and accretionary complex zones in the world,and its geological records provide the best opportunity to make new breakthroughs in understanding of the plate tectonics.

关键词： Accretionary complex Subduction of oceanic plate Tectonic scraping Accretionary orogenic belt Collisional orogenic belt

β-Ga_(2)O_(3)热电性能的第一性原理计算

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原子与分子物理学报 2025年第1期42卷 180-188页

作者：邓南发周贤中广东工业大学集成电路学院广州510006

通过使用第一性原理计算方法和玻尔兹曼输运理论,计算了β-Ga_(2)O_(3)的电学、热学和热电性质,并得出了热电性能因子随载流子浓度和温度的变化规律.此外,还考虑了声子散射和极性光学声子散射对平均电子弛豫时间的影响,并详细描述了不... 详细信息

通过使用第一性原理计算方法和玻尔兹曼输运理论,计算了β-Ga_(2)O_(3)的电学、热学和热电性质,并得出了热电性能因子随载流子浓度和温度的变化规律.此外,还考虑了声子散射和极性光学声子散射对平均电子弛豫时间的影响,并详细描述了不同载流子浓度和温度下β-Ga_(2)O_(3)的Seebeck系数、电导率、电热导率和功率因数的计算结果.最后,给出了β-Ga_(2)O_(3)的热电性能因子随载流子浓度和温度的变化趋势.结果表明,在高载流子浓度和高温下,β-Ga_(2)O_(3)具有较高的热电性能因子.

关键词： Ga_(2)O_(3) 第一性原理计算波尔兹曼输运理论热电性质

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山姜素调节cAMP/PKA/CREB信号通路促进骨质疏松性骨折大鼠骨折愈合

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中国组织工程研究 2025年第12期29卷 2438-2443页

作者：陆飞周静金涛连云港市第一人民医院康复医学科江苏省连云港市222000 南京医科大学康达学院康复医学部江苏省连云港市222000 中国人民解放军东部战区总医院健康医学科江苏省南京市210018

背景:山姜素具有抗炎、抗肿瘤、抗菌等作用,已被证实能够缓解骨质疏松症,但山姜素对骨质疏松性骨折的影响及机制仍不清楚。目的:探讨山姜素调节环磷酸腺苷/蛋白激酶A/环磷酸腺苷反应元件结合蛋白信号通路对骨质疏松性骨折大鼠的改善作... 详细信息

背景:山姜素具有抗炎、抗肿瘤、抗菌等作用,已被证实能够缓解骨质疏松症,但山姜素对骨质疏松性骨折的影响及机制仍不清楚。目的:探讨山姜素调节环磷酸腺苷/蛋白激酶A/环磷酸腺苷反应元件结合蛋白信号通路对骨质疏松性骨折大鼠的改善作用。方法:采用双侧卵巢切除手术构建骨质疏松症骨折大鼠模型,将成功造模大鼠依据随机数字表法分为山姜素低、中、高剂量组、抑制剂组和模型组,另选12只大鼠作为假手术组。骨折造模当天,山姜素低、中、高剂量组大鼠灌胃7.5,15,30 mg/kg的山姜素+腹腔注射等量的生理盐水,抑制剂组灌胃30 mg/kg的山姜素+腹腔注射5 mg/kg的H-89(通路抑制剂),模型组与假手术组给予(灌胃+腹腔注射)等量生理盐水,1次/d,连续8周。放射性检查评估大鼠骨折愈合情况并进行愈合评分;骨密度扫描仪测定骨折处骨密度;通过三点弯曲实验和压缩实验评估大鼠股骨生物力学状况;苏木精-伊红染色观察大鼠骨折处病理损伤;酶联免疫吸附(ELISA)法检测血清碱性磷酸酶、骨钙素和Ⅰ型胶原交联C-末端肽、环磷酸腺苷水平的变化;Western blot检测股骨组织中骨形态发生蛋白2和环磷酸腺苷/蛋白激酶A/环磷酸腺苷反应元件结合蛋白通路蛋白表达。结果与结论:①相较于假手术组,模型组大鼠骨折愈合评分、骨密度、最大负荷、最大应力、碱性磷酸酶、骨钙素、环磷酸腺苷水平、骨形态发生蛋白2、磷酸化蛋白激酶A/蛋白激酶A、磷酸化环磷酸腺苷反应元件结合蛋白/环磷酸腺苷反应元件结合蛋白表达下降,Ⅰ型胶原交联羧基末端肽水平增加(P<0.05);与模型组比较,山姜素各剂量组大鼠上述各项指标呈现相反的变化(P<0.05);与山姜素高剂量组比较,抑制剂组大鼠上述指标变化均被逆转(P<0.05)。②结论:山姜素可能通过激活环磷酸腺苷/蛋白激酶A/环磷酸腺苷反应元件结合蛋白信号通路加速骨质疏松症骨折大鼠的骨折愈合。

关键词：山姜素环磷酸腺苷/蛋白激酶A/环磷酸腺苷反应元件结合蛋白骨质疏松骨折愈合大鼠

全球价值链前向嵌入与制造业出口隐含碳排放——兼论数字服务贸易自由化的调节效应

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国际商务研究 2025年第1期46卷 1-17页

作者：周宏伟刘曙光南开大学天津300071 中国海洋大学山东青岛266100

全球价值链分工对贸易隐含碳排放的影响受到学界广泛关注。本文实证检验全球价值链前向嵌入影响出口隐含碳排放的理论机制,进一步分析数字服务贸易自由化的调节效应。研究发现:全球价值链前向嵌入、简单嵌入对出口隐含碳排放的影响呈倒U... 详细信息

全球价值链分工对贸易隐含碳排放的影响受到学界广泛关注。本文实证检验全球价值链前向嵌入影响出口隐含碳排放的理论机制,进一步分析数字服务贸易自由化的调节效应。研究发现:全球价值链前向嵌入、简单嵌入对出口隐含碳排放的影响呈倒U型,而复杂嵌入具有显著的抑制效应;发达国家与欧洲价值链网络区域全球价值链前向嵌入对出口隐含碳排放的影响呈倒U型,而发展中国家、北美价值链和亚洲价值链网络区域全球价值链前向嵌入具有显著的抑制效应;相对于高技术行业,全球价值链前向嵌入与低技术行业出口隐含碳排放的倒U型关系更为显著。调节效应表明:数字服务贸易自由化提前了全球价值链前向嵌入与出口隐含碳排放倒U型曲线的拐点,该效应在发达国家、欧洲价值链网络区域以及低技术行业中更加明显;数字服务贸易自由化增强了发展中国家、亚洲价值链网络区域以及复杂嵌入的出口减排效应。本文结论对全球价值链视角下中国经济绿色低碳发展具有重要启示。

关键词：全球价值链出口隐含碳排放倒U型数字服务贸易自由化调节效应

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新生儿坏死性小肠结肠炎的治疗进展

医学综述 2025年第1期31卷 41-45页

作者：周宇周静王朝阳内蒙古医科大学第一临床医学院呼和浩特010030 内蒙古医科大学基础医学院呼和浩特010080 内蒙古医科大学附属医院小儿外科呼和浩特010050

新生儿坏死性小肠结肠炎(NEC)是一种严重威胁新生儿特别是早产儿的肠道疾病,表现为肠壁组织坏死以及相应肠段的炎症。NEC起病迅速,病情进展快,具有高发病率和高病死率等特点,已成为导致新生儿及早产儿死亡的重要因素。因此,早期诊断、治... 详细信息

新生儿坏死性小肠结肠炎(NEC)是一种严重威胁新生儿特别是早产儿的肠道疾病,表现为肠壁组织坏死以及相应肠段的炎症。NEC起病迅速,病情进展快,具有高发病率和高病死率等特点,已成为导致新生儿及早产儿死亡的重要因素。因此,早期诊断、治疗NEC十分关键。近年来,Toll样受体抑制剂、远程缺血性调节、干细胞治疗、母乳成分(人乳低聚糖、外泌体、乳铁蛋白)治疗、粪菌移植等新型治疗方法逐渐应用于临床,可降低NEC的发生率和病死率,改善患儿远期预后,为NEC的治疗提供了新思路。

关键词：坏死性小肠结肠炎新生儿危险因素治疗方法

DETERMINATION　OF　STATES　OF　STRESS　AND　STRAIN　AT　POLE　OF　HYDRAULIC　BULGE　ORTHOTROPIC　SHEET　SAMPLE

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中国有色金属学会会刊：英文版 1995年第3期5卷 84-87页

作者： zhou, Weixian zhou, Xin Northwestern Polytechnical Univ Xi'an China

ＤＥＴＥＲＭＩＮＡＴＩＯＮＯＦＳＴＡＴＥＳＯＦＳＴＲＥＳＳＡＮＤＳＴＲＡＩＮＡＴＰＯＬＥＯＦＨＹＤＲＡＵＬＩＣＢＵＬＧＥＯＲＴＨＯＴＲＯＰＩＣＳＨＥＥＴＳＡＭＰＬＥ￥Ｚｈｏｕ，Ｗｅｉｘｉａｎ；Ｚｈｏｕ，Ｘｉｎ（Ｄｅｐ... 详细信息

ＤＥＴＥＲＭＩＮＡＴＩＯＮＯＦＳＴＡＴＥＳＯＦＳＴＲＥＳＳＡＮＤＳＴＲＡＩＮＡＴＰＯＬＥＯＦＨＹＤＲＡＵＬＩＣＢＵＬＧＥＯＲＴＨＯＴＲＯＰＩＣＳＨＥＥＴＳＡＭＰＬＥ￥Ｚｈｏｕ，Ｗｅｉｘｉａｎ；Ｚｈｏｕ，Ｘｉｎ（ＤｅｐａｒｔｍｅｎｔｏｆＡｅｒｏｎａｕｔ...

关键词： orthotropic sheet hydraulic bulge specimen pole stress state strain state

Image copy-move forgery passive detection based on improved PCNN and self-selected sub-images

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Frontiers of Computer Science 2022年第4期16卷 131-146页

作者： Guoshuai zhou Xiuxia Tian Aoying zhou School of Computer Science and Technology ShangHai University of Electric PowerShanghai200090China School of Data Science and Engineering East China Normal UniversityShanghai200062China

Image forgery detection remains a challenging *** the most common copy-move forgery detection,the robustness and accuracy of existing methods can still be further *** the best of our knowledge,we are the first to propose an image copy-move forgery passive detection method by combining the improved pulse coupled neural network(PCNN)and the self-selected *** method has the following steps:First,contour detection is performed on the input color image,and bounding boxes are drawn to frame the contours to form suspected forgery ***,by improving PCNN to perform feature extraction of sub-images,the feature invariance of rotation,scaling,noise adding,and so on can be ***,the dual feature matching is used to match the features and locate the forgery ***’s more,the self-selected sub-images can quickly obtain suspected forgery sub-images and lessen the workload of feature extraction,and the improved PCNN can extract image features with high *** experiments on the standard image forgery datasets CoMoFoD and CASIA,it is effectively verified that the robustness score and accuracy of proposed method are much higher than the current best method,which is a more efficient image copy-move forgery passive detection method.

关键词： image copy-move forgery passive detection self-selected sub-images pulse coupled neural network(PCNN) dual feature matching

Effect of adding Nb foil on joint properties of laser fusion welding for TC4 titanium and 7075 aluminum alloy

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Chinese Journal of Aeronautics 2023年第5期36卷 508-521页

作者： Jiafu zhou Dianwu zhou Huiming LI State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body Hunan UniversityChangsha 410082China

It is difficult to gain effective Ti-Al fusion welding joints due to their differences in thermal properties and the appearance of brittle Ti-Al Intermetallic Compounds(IMCs).The experiments of laser fusion welding for TC4 titanium and 7075 aluminum alloy were carried out,temperature field and ductility/brittleness,as well as chemical potential of elements,were calculated,and the effect of adding Nb foil on mechanical properties of the weld was also *** results suggested that Nb atoms tend to diffuse toward Al side,which is conducive to the participation of Nb in the metallurgical reaction and contributes to forming the Ti-Nb-Al IMC layer at the *** the thickness of Nb foil increases,the tensile-shear force of joint climbs first but then declines,and reaches the highest value of 1663 N with 0.10 mm-thickness Nb foil,representing 58.38%enhancement compared with the non-added *** Nb foil slows down the heat transfer as a blocker,and thus both the melting amount of Al and the mixing area of Ti and Al *** addition,Nb alloying reduces the brittleness of the Ti-Al ***,the joint properties of titanium/aluminum are improved with the addition of Nb foil.

关键词： Aluminum alloys Intermetallic compounds Laser lap fusion welding Mechanical property Nb foil Titanium alloys

Spatially targeting of tumor-associated macrophages and cancer cells for suppression of spontaneously metastatic tumor

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Nano Research 2022年第4期15卷 3446-3457页

作者： Minglu zhou Dandan Xie zhou zhou Lian Li Yuan Huang Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial TechnologyWest China School of PharmacySichuan UniversityChengdu 610041China

The interaction between cancer cells and M2 tumor-associated macrophages(M2-TAMs)facilitates tumor growth and ***,cancer cells and M2-TAMs have different spatial distribution patterns,which requires distinct drug delivery ***,based on different tumor-penetrating ability of nanocarriers,we developed a combinatory strategy that consists of a TAMs-targeting liposome(alanine-alanine-asparagine(AAN)-Lip-regorafenib(Rego))and a cancer cells-targeting copolymer(internalizing RGD modified with N-(2-hydroxypropyl)methacrylamide-doxorubicin(iRGD-HD)).Our study confirmed AAN-Lip-Rego accumulated at perivascular sites where M2-TAM is located,while iRGD-HD penetrated into deep site of tumor to enter cancer ***,we found iRGD-HD induced cancer cells undergoing immunogenic cell death to enhance tumor infiltration of CD8^(+)T ***,AAN-Lip-Rego efficiently repolarized TAMs from M2 into M1 to alleviate tumor immunosuppression,thus reviving CD8^(+)T ***,the repolarization of TAMs led to dramatic downregulation of prometastatic factors expressed on cancer *** a result,such combinatory approach elicited robust antitumor immune responses and generated considerable anti-tumor and anti-metastasis efficacy to markedly inhibit primary tumor and spontaneous lung metastasis.

关键词： spatial distribution tumor-associated macrophage immunogenic cell death anti-tumor immunity cancer metastasis