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The MabHLH11 transcription factor interacting with MaMYB4 acts additively in increasing plant scopolin biosynthesis

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The Crop Journal 2023年第6期11卷 1675-1685页

作者： Zhen Duan shengsheng wang Zhengshe Zhang Qi Yan Caibin Zhang Pei Zhou Fan Wu Jiyu Zhang State Key Laboratory of Herbage Improvement and Grassland Agro-ecosystems Key Laboratory of Grassland Livestock Industry InnovationMinistry of Agriculture and Rural AffairsCollege of Pastoral Agriculture Science and TechnologyLanzhou UniversityLanzhou 730020GansuChina

The plant natural product scopolin,a coumarin secondary metabolite,has been extensively exploited in flavor,cosmetic,medicine,and other industrial fields.Melilotus albus,a leguminous rotation crop,contains high concentrations of coumarin.The transcriptional regulatory network that controls the flow through the scopolin biosynthesis pipeline in M.albus remains poorly understood.MabHLH11 encodes a basic helix–loop–helix(bHLH)transcription factor whose transcription is positively associated with scopolin accumulation and with the expression of MaMYB4,the bHLH partner of the MYB-bHLH complex.Phylogenetic analysis grouped MabHLH11 in the TRANSPARENT TESTA 8(TT8)clade of the bHLH IIIf subgroup.The MabHLH11 protein contained an MYB-interacting region and physically interacted with MaMYB4 in yeast and tobacco leaves.Co-overexpression of MabHLH11 with MaMYB4 in M.albus additively increased the expression of UDP-glucosyltransferase(MaUGT79)and induced more scopolin accumulation than occurred under the expression of MabHLH11 alone.MabHLH11 directly targeted the promoter of MaUGT79 and the activation of MabHLH11 was strengthened by the presence of MaMYB4.Thus,MaMYB4 enhanced the function of MabHLH11 in upregulating scopolin biosynthesis in M.albus,providing a theoretical basis for scalable production of a high-value plant natural product.

关键词： Melilotus albus Scopolin accumulation Mabhlh11 Mamyb4 Maugt79

Feature Selection with Fluid Mechanics Inspired Particle Swarm Optimization for Microarray Data

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Journal of Beijing Institute of Technology 2017年第4期26卷 517-524页

作者： shengsheng wang Ruyi Dong College of Computer Science and Technology Jilin UniversityChangchun 130012China Jilin Vocational College of Industry and Technology JilinJilin 132013China

Deoxyribonucleic acid（ DNA） microarray gene expression data has been widely utilized in the field of functional genomics,since it is helpful to study cancer,cells,tissues,organisms etc.But the sample sizes are relatively small compared to the number of genes,so feature selection is very necessary to reduce complexity and increase the classification accuracy of samples. In this paper,a completely newimprovement over particle swarm optimization（ PSO） based on fluid mechanics is proposed for the feature selection. This newimprovement simulates the spontaneous process of the air from high pressure to lowpressure,therefore it allows for a search through all possible solution spaces and prevents particles from getting trapped in a local optimum. The experiment shows that,this newimproved algorithm had an elaborate feature simplification which achieved a very precise and significant accuracy in the classification of 8 among the 11 datasets,and it is much better in comparison with other methods for feature selection.

关键词： feature selection particle swarm optimization （PSO） fluid mechanics （FM） microarray data support vector machine （SVM）

Design Strategies and Practice Paths for Improving Urban Quality in the Stock Era

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Journal of Landscape Research 2024年第2期16卷 18-24页

作者： Li Tianfei Zhou Xiaotian Han shengsheng Liu Yuxuan Power China Huadong Engineering Corporation Limited HangzhouZhejiang 311500China

In the middle and later stages of urbanization development,the growth of the real estate industry will stagnate,and urban renewal will become the mainstream.With the advancement of urban renewal,there are still problems in improving the quality of cities in the stock era and their design strategies.This paper analyzed the Linping Old City organic renewal project and the Xishui River ecological governance project in the stock era of urban quality improvement by sorting out the current development status,historical background,planning types,and design strategies of quality improvement in the stock era from the perspective of urban renewal,combining with project overview,main problems,design methods,and design content.Urban renewal is the leading direction for promoting urban development and construction on a global scale,and countries formulate different plans and practices based on their local characteristics.Urban renewal strategies should be diversified,and focus on livable environments,urban characteristics,etc.,while considering human factors,green innovation,etc.,in order to achieve smart community management and enhance the economic and social benefits brought by urban attractiveness.For successful cases such as the Linping Old City and Xishui River ecological governance project,corresponding urban quality improvement strategies and implementation plans should be formulated according to local conditions,with emphasis on social participation and people’s livelihood improvement.This study can help urban planning pay more attention to rational utilization and upgrading of existing urban resources,adapt to the current urban development situation,and promote sustainable urban development.

关键词： Stock era Organic renewal Ecological governance Linping Old City Xishui River

The spectrum of rare monogenic diseases in patients with premature coronary artery disease

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中华医学杂志(英文版) 2024年第10期137卷 2024 Feb 1页

作者： Teng Yaqun Du Tian Feng Siqin Tian Ran Liu Yaping Guo Jian wang Lei Zhang Zhiyu Luan Xiaodong He Shan Zhuang shengsheng wang Yifei Zhang Shuyuan Chen Shi Liu Zhenyu Zhang Shuyang Department of Cardiology State Key Laboratory of Complex Severe and Rare disease Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Department of Internal Medicine Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Department of Basic Medical Sciences Tsinghua University School of Medicine Beijing China Department of Breast Oncology Sun Yat-sen University Cancer Center Guangzhou Guangdong China McKusick-Zhang Center for Genetic Medicine State Key Laboratory of Medical Molecular Biology Institute of Basic Medical Sciences Chinese Academy of Medical Sciences School of Basic Medicine Peking Union Medical College Beijing China Tsinghua University-Peking University Joint Center for Life Sciences Beijing China Department of Cardiology Beijing Tsinghua Changgung Hospital Tsinghua University Beijing China Department of Endocrinology Key Laboratory of Endocrinology of National Health Commission Peking Union Medical College Hospital Chinese Research Center for Behavior Medicine in Growth and Development Beijing China

Mutations in wheat TaAPA2 gene result in pleiotropic effects on plant architecture

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Science China Life Sciences 2024年

作者： shengsheng Bai Guiping wang Rui Song Yanna Liu Lei Hua Jinwei Yang Lijun Zhang Shams ur Rehman Xiaohua Hao Lifeng Hou Chaozhong Zhang Hongna Li Yanyan Liang Lihua Zhao Yan Xue Zheng wang Shisheng Chen National Key Laboratory of Wheat Improvement Peking University Institute of Advanced Agricultural Sciences Shandong Laboratory of Advanced Agriculture Sciences in Weifang Department of Plant Sciences University of CaliforniaDavis

Dear Editor,Bread wheat (Triticum aestivum L.) is a globally important cereal providing～20% of the calories and proteins for>4.5 billion people. Plant architecture, including morphologies of leaves, spikes, stems,and roots, has great impact on plant development and productivity, and thus has been extensively investigated in various plant species (Jiang et al., 2023;Zhang et al., 2017). However, studies on the genes and molecular mechanisms regulating plant architecture in wheat remain limited.

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日本推动对华“反经济胁迫”议题的研究——以日本核污染水排海为例

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太平洋学报 2024年第4期32卷 30-43页

作者：周生升上海国际问题研究院上海200233

近年来,随着大国博弈加剧和中日实力差距不断扩大,日本认为中国的经济崛起对其国家安全利益造成“威胁”,并将使地区秩序朝向不利于日本的方向发展,需要通过与美国及其他“志同道合的国家”塑造新的规则、规范来限制中国。在此背景下,... 详细信息

近年来,随着大国博弈加剧和中日实力差距不断扩大,日本认为中国的经济崛起对其国家安全利益造成“威胁”,并将使地区秩序朝向不利于日本的方向发展,需要通过与美国及其他“志同道合的国家”塑造新的规则、规范来限制中国。在此背景下,加快推进对华“反经济胁迫”议题成为日本规锁中国的新抓手。2023年8月,日本在强推核污染水排海遭到中国反制后,立刻利用“反经济胁迫”议题进行对抗,意欲向国内外展示该议题的“必要性”和“有效性”,同时转嫁自身危机。然而,日本对于“反经济胁迫”议题的认知以及推动具有明显的工具主义和双重标准,实质上是为打压异己、维护以美国为核心的霸权秩序,背离了真正的多边主义。

关键词：经济安全 “经济胁迫” “反经济胁迫” 中日关系

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Assessment of tree-ring mercury radial translocation and age effect in Masson pine:Implications for historical atmospheric mercury reconstruction

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Journal of Environmental Sciences 2024年第4期138卷 266-276页

作者： Xu Liu Xun wang Dingyong wang College of Resources and Environment Southwest UniversityChongqing 400715China State Key Laboratory of Environmental Geochemistry Institute of GeochemistryChinese Academy of SciencesGuiyang 550081China

The tree ring has been regarded as an emerging archive to reconstruct historical atmospheric mercury(Hg)trends,but with the large knowledge gaps in the reliability.In this study,we comprehensively evaluated the Hg source,radial translocation and age effect of Masson pine(Pinus massoniana)tree ring at Mt.Jinyun in Chongqing,to assess the suitability of such tree ring as the archive of atmospheric Hg.Results showed that distinct variabilities among Masson pine tree-ring Hg concentration profiles.The Hg concentration significantly increased along with stem height(P<0.05),indicating the Hg in tree rings mainly derived from foliage uptake atmospheric Hg.We found a distinct age effect that the tree ring of young trees had the higher Hg concentration.Besides,we used the advection-diffusion model to demonstrate how Hg concentration shifted by the advection or/and diffusion in tree rings.The modeling results showed that the advection induced radial translocation during the young growth period of tree was a plausible mechanism to result in the tree-ring Hg record largely different from the trend of anthropogenic Hg emissions in Chongqing.We finally suggest that in further Hg dendrochemistry,better discarding the tree-ring Hg profile of the young growth period to reduce impacts of the radial translocation and age effect.

关键词： Masson pine Tree-ring mercury Radial translocation Tree age effect

Pushing the boundaries: an interview with Dae-Hyun Kim on terahertz devices

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National Science Review 2024年第3期11卷 42-45页

作者： Defu wang the Center for Carbon-based Electronics School of Electronics Peking University

Ⅲ–Ⅴ compound semiconductors, such as InGaAs/InAlAs, exhibit exceptional carrier transport properties, establishing them as fundamental elements in terahertz(THz) applications crucial for the development of 6G netwo...

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Improved Qualitative Trajectory Calculus for Pair-Activity Analysis

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Journal of Beijing Institute of Technology 2019年第2期28卷 318-326页

作者： shengsheng wang Guangyao wang Yungang Zhu Jingwen Shao College of Computer Science and Technology Jilin University

Trajectory provides the most robust feature for activity recognition in far-field surveillance videos,in which increasing attentions have been given to the use of qualitative methods with symbolic rather than real-value features.Qualitative trajectory calculus(QTC)showed a good performance in pair-activity from video.However,QTC and similar works are not good at dealing with noise,since they are all considering short-term features.To deal with the problems mentioned above,two types of long-term features,including sub-trajectory feature and point-trajectory feature,are designed.The sub-trajectory feature is a long-term feature in a coarse granularity,while the point-trajectory feature is a long-term feature in a relatively fine granularity.Using the sub-trajectory feature,a couple of trajectories are segmented into sub-trajectories and enveloping boxes are used to substitute the original sub-trajectory for capturing the major attributes.The point-trajectory feature describes the relationship between a single point in one trajectory and all parts of the other trajectory.The experiments on the human activity classification data demonstrated that our proposed methods are better than the original QTC and previous short-term features.

关键词： pair-activity analysis qualitative trajectory calculus sub-trajectory feature point-trajectory feature