检索结果-南通市图书馆

Mitochondrial-targeting Mn_(3)O_(4)/UIO-TPP nanozyme scavenge ROS to restore mitochondrial function for osteoarthritis therapy

在线全文

学校读者我要写书评

暂无评论

Regenerative Biomaterials 2023年第1期10卷 1451-1467页

作者： shengqing zhang Jinhong Cai Yi Yao Lanli Huang Li Zheng Jinmin Zhao Collaborative Innovation Centre of Regenerative Medicine and Medical Bioresource Development and Application Co-constructed by the Province and Ministry The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021China Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021China Life Sciences Institute Guangxi Medical UniversityNanning 530021China Department of Orthopedics The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021China

Excessive reactive oxygen species(ROS)-induced mitochondrial damage has impact on osteoarthritis(OA).Nanozyme mimics as natural enzyme alternatives to scavenge excessive ROS has offered a promising strategy for OA ***,we reported a novel mitochondrial-targeting Mn_(3)O_(4)/UIO-TPP nanozyme using metal-organic frameworks with loaded Mn_(3)O_(4)as the enzyme-like active core combining mitochondria-targeting triphenylphosphine(TPP)groups to serve as ROS scavengers for therapy of *** sequential catalysis of superoxide dismutase-like,catalase(CAT)-like,and hydroxyl radical(·OH)scavenging potentials,the nanozyme can target mitochondria by crossing subcellular barriers to effectively eliminate ROS to restore mitochondrial function and inhibit inflammation and chondrocyte *** also has favorable biocompatibility and *** on anterior cruciate ligament transection-induced OA joint models,this mitochondrial-targeting nanozyme effectively mitigated the inflammatory response with the Pelletier score reduction of 49.9%after 8-week *** study offers a prospective approach to the design of nanomedicines for ROS-related diseases.

关键词： Mn_(3)O_(4) nanozyme ROS scavenging mitochondrial-targeting osteoarthritis

A FAST BIT-LOADING ALGORITHM FOR HIGH SPEED POWER LINE COMMUNICATIONS

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Electronics(China) 2012年第5期29卷 461-468页

作者： zhang shengqing Zhao Li Zou Cairong Key Laboratory of Underwater Acoustic Signal Processing of Ministry of Education SouthEast University

Adaptive bit-loading is a key technology in high speed power line communications with the Orthogonal Frequency Division Multiplexing (OFDM) modulation technology. According to the real situation of the transmitting power spectrum limited in high speed power line communications, this paper explored the adaptive bit loading algorithm to maximize transmission bit number when transmitting power spectral density and bit error rate are not exceed upper limit. With the characteristics of the power line channel, first of all, it obtains the optimal bit loading algorithm, and then provides the improved algorithm to reduce the computational complexity. Based on the analysis and simulation, it offers a non-iterative bit allocation algorithm, and finally the simulation shows that this new algorithm can greatly reduce the computational complexity, and the actual bit allocation results close to optimal.

关键词： Power line communications Orthogonal Frequency Division Multiplexing (OFDM) Bit-loading

Ecological health analysis of wetlands in the middle reaches of Yangtze River under changing environment

在线全文

学校读者我要写书评

暂无评论

International Journal of Digital Earth 2023年第1期16卷 3125-3144页

作者： shengqing zhang Xiaoyan Zhai Peng Yang Jun Xia Sheng Hu Libo Zhou Cai Fu Hubei Key Laboratory of Regional Ecology and Environmental Change School of Geography and Information EngineeringChina University of GeosciencesWuhanPeople’s Republic of China State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin Research Center on Flood and Drought Disaster ReductionChina Institute of Water Resources and Hydropower ResearchBeijingPeople’s Republic of China State Key Laboratory of Water Resources and Hydropower Engineering Science Wuhan UniversityWuhanPeople’s Republic of China Yangtze Valley Water Environment Monitoring Center WuhanPeople’s Republic of China Wuhan CGeo Clouds Science&Tech Co.Ltd WuhanPeople’s Republic of China

Changes in wetland ecosystems have a critical impact on the local ecology and species *** development scenarios and policies are key factors influencing their ***,we studied changes of wetlands in the middle Yangtze River basin(MYRB)in 2001-2020,and a patch-generated land use simulation(PLUS)model and random forest(RF)method were applied to predict and analyze the changes under different scenarios in the MYRB in the future(i.e.2035-2095).The results indicated that:(1)The regions with high wetland proportions were concentrated in the central and eastern MYRB in 2001-2020,with a 1.5%decrease in overall wetland area;(2)The RF could simulate the future ecological quality with training and testing accuracies of 0.98 and 0.92,respectively;(3)Remote Sensing Ecological Index(RSEI)less than 0.5 in the central and eastern regions and 13.3%reduction in the northwest in the SSP245 *** general,the study provides a basis for future regional studies of ecosystem quality and provides data to support wetland conservation and management.

关键词： Remote sensing machine learning ecological prediction ecological change Yangtze River basin

ORIENTATION OF MOLECULAR GROUPS IN CROSS SECTION OF POLYAMIDE-6 FIBER BY INFRARED ATTENUATED TOTAL REFLECTION DICHROISM STUDIES

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

高分子科学(英文版) 1987年第2期5卷 149-155页

作者：沈德言张盛庆 Institute of Chemistry Academia Sinica Beijing Institute of Chemistry Academia Sinica Beijing

The polymer fiber usually possess typical uniaxial orientation. The molecular chains are symmetrically distributed around fiber axis. In this work, the orientation of molecular groups in the cross section of polyamide-6 fiber has been measured by using IR ATR method. The results indicated that the polyamide-6 fiber mainly contains α-crystalline form. The direction of hydrogen bonds of amide groups is predominately parallel with the surface in the cross section of the fiber.

关键词： Fiber Infrared Dichroism Orientation Polyamide-6

Advancements in life-on-a-chip: The impact of “Beyond Limits Manufacturing” technology

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第5期35卷 13-16页

作者： Weiwei He Hongbo zhang Xudong Lin Lili Zhu Tingting Zheng Hao Pei Yang Tian Min zhang Guoyue Shi Lei Wu Jianlong Zhao Gulinuer Wumaier shengqing Li Yufang Xu Honglin Li Xuhong Qian Shanghai Key Laboratory of New Drug Design School of PharmacyEast China University of Science and TechnologyShanghai 200237China School of Mechanical and Power Engineering East China University of Science and TechnologyShanghai 200237China Guangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument School of Biomedical EngineeringShenzhen Campus of Sun Yat-sen UniversityShenzhen 518000China Shanghai Key Laboratory of Green Chemistry and Chemical Processes Department of ChemistrySchool of Chemistry and Molecular EngineeringEast China Normal UniversityShanghai 200241China Shanghai Institute of Microsystem and Information Technology Chinese Academy of SciencesShanghai 200050China Department of Pulmonary and Critical Care Medicine Huashan HospitalFudan UniversityShanghai 200040China Innovation Center for AI and Drug Discovery East China Normal UniversityShanghai 200062China Lingang Laboratory Shanghai 200031China

This review explores the concept of life-on-a-chip,which involves the creation of miniaturized biological systems,such as organs,tissues,and model organisms,on microscale platforms called microfluidic *** chips consist of intricately etched channels,wells,and chambers that enable precise control and observation of fluids,cells,and biochemical reactions,facilitating the simulation of various aspects of human or animal physiology and the study of responses to different stimuli,drugs,or disease *** review highlights the application of a novel technology,“Beyond Limit Manufacturing”(BLM),in the development of sophisticated three-dimensional cell models and model organism ***-on-a-chip and organ-on-a-chip(OoC)are among the thriving developments in the field of microfluidics,allowing for the reconstruction of living microenvironments and implementation of multiple *** review discusses the latest advancements in life-on-a-chip technology using BLM and outlines potential future research directions,emphasizing the significant role of these chips in studying complex biological processes in a controlled and scalable manner.

关键词： Beyond Limit Manufacturing Model-organism-on-a-chip Organ-on-a-chip

在线全文

学校读者我要写书评

暂无评论

银川阅海公园水生植物园规划

中国农学通报 2010年第17期26卷 218-222页

作者：哈梅娟张生清银川市银西生态防护林管理处银川750021 银川毓秀环艺工程有限公司银川750001

银川阅海湿地公园是国家级湿地公园,对银川阅海公园水生植物园的规划建设,可以完善阅海湿地公园的整体布局、功能及生态系统,促进银川阅海公园生态与经济的和谐发展。同时此项目的规划建设对提高银川地区水生植物资源的开发利用、保护... 详细信息

银川阅海湿地公园是国家级湿地公园,对银川阅海公园水生植物园的规划建设,可以完善阅海湿地公园的整体布局、功能及生态系统,促进银川阅海公园生态与经济的和谐发展。同时此项目的规划建设对提高银川地区水生植物资源的开发利用、保护生物多样性、扩大银川阅海公园的知名度将产生积极而深远的影响。

关键词：水生植物园规划资源保护和开发利用多样性

在线全文

学校读者我要写书评

暂无评论

高职公共课程的内涵与作用

上海电机技术高等专科学校学报 2000年第2期3卷 14-18页

作者：张圣勤上海电机技术高等专科学校图书馆，上海200240

阐述了高职公共课程的内涵及其在高职教育中的作用，并介绍了公共课程定位的三种模式及自的特点，从理论对对高职公共课程的内涵和作用作了有益地探讨。

关键词：公共课程内涵作用高等职业技术教育课程设置

Diatomic Pd catalyst with conjugated backbone for synergistic electrochemical CO_(2)reduction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第6期17卷 4850-4855页

作者： Wenxuan zhang Mengran zhang Hongjuan Wang Wen zhang Min zhang MOE International Joint Laboratory of Materials Microstructure Institute for New Energy Materials and Low Carbon TechnologiesSchool of Materials Science and EngineeringTianjin University of TechnologyTianjin 300384China Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion School of Chemistry and Chemical EngineeringTianjin University of TechnologyTianjin 300384China

Double-site catalysts have attracted widespread attention in the field of electrocatalysis due to their high metal loading,adjustable active centres,and electronic valence ***,the development of bimetallic sites catalysts that coordinate with definite atoms is still in the exploratory ***,we designed and synthesized a bimetallic palladium complex(BPB-Pd_(2))with conjugated *** supported BPB-Pd_(2)was applied to electrochemical CO_(2)reduction reaction(CO_(2)RR)for the first *** as-obtained BPB-Pd_(2)gives an exceptional Faradaic efficiency of CO(FECO)of 94.4%at−0.80 V *** hydrogen electrode(RHE),which is significantly superior to monoatomic palladium catalyst(BPB-Pd1).The density functional theory(DFT)calculations revealed that the essential reason for the outstanding activity of BPB-Pd_(2)toward CO_(2)RR was that the electronic effect between diatomic palladium reduces the free energy change for CO_(2)RR ***,BPB-Pd_(2)exhibits moderate free energy change to form COOH*intermediate,which was beneficial for the generation of CO in CO_(2)RR.

关键词： synthesis electrocatalysis CO_(2)reduction bimetallic palladium complex synergistic catalysis

N-doped graphene quantum dot-decorated N-TiO2/P-doped porous hollow g-C_(3)N_(4) nanotube composite photocatalysts for antibiotic photodegradation and H2 production

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2024年第1期31卷 165-178页

作者： Jingshu Yuan Yao zhang Xiaoyan zhang Junjie zhang Shen’gen zhang Institute for Advanced Materials and Technology University of Science and Technology BeijingBeijing 100083China Xi’an Fanyi University Xi’an 710105China Shunde Graduate School of University of Science and Technology Beijing Foshan 528399China State Key Laboratory of Lunar and Planetary Sciences Macao University of Science and TechnologyMacao SAR 820000China

Exclusive responsiveness to ultraviolet light (~3.2 eV) and high photogenerated charge recombination rate are the two primary drawbacks of pure TiO_(2). We combined N-doped graphene quantum dots (N-GQDs), morphology regulation, and heterojunction construction strategies to synthesize N-GQD/N-doped TiO_(2)/P-doped porous hollow g-C_(3)N_(4) nanotube (PCN) composite photocatalysts (denoted as G-TPCN). The optimal sample (G-TPCN doped with 0.1wt% N-GQD, denoted as 0.1% G-TPCN) exhibits significantly enhanced photoabsorption, which is attributed to the change in bandgap caused by elemental doping (P and N), the improved light-harvesting resulting from the tube structure, and the upconversion effect of N-GQDs. In addition, the internal charge separation and transfer capability of0.1% G-TPCN are dramatically boosted, and its carrier concentration is 3.7, 2.3, and 1.9 times that of N-TiO_(2), PCN, and N-TiO_(2)/PCN(TPCN-1), respectively. This phenomenon is attributed to the formation of Z-scheme heterojunction between N-TiO_(2) and PCNs, the excellent electron conduction ability of N-GQDs, and the short transfer distance caused by the porous nanotube structure. Compared with those of N-TiO_(2), PCNs, and TPCN-1, the H2 production activity of 0.1%G-TPCN under visible light is enhanced by 12.4, 2.3, and 1.4times, respectively, and its ciprofloxacin (CIP) degradation rate is increased by 7.9, 5.7, and 2.9 times, respectively. The optimized performance benefits from excellent photoresponsiveness and improved carrier separation and migration efficiencies. Finally, the photocatalytic mechanism of 0.1% G-TPCN and five possible degradation pathways of CIP are proposed. This study clarifies the mechanism of multiple modification strategies to synergistically improve the photocatalytic performance of 0.1% G-TPCN and provides a potential strategy for rationally designing novel photocatalysts for environmental remediation and solar energy conversion.

关键词： N-doped TiO_(2) N-doped graphene quantum dots P-doped g-C_(3)N_(4) porous hollow nanotube heterojunction photocatalysis