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Journal of Traditional Chinese Medical Sciences 2023年第2期10卷 127-128页

作者： Tingyu Fang shenglou ni Yanping Wang Xiaoli Li Liangxiao Ma Ochs Shelley School of Humanities Beijing University of Chinese MedicineBeijing102488China Periodical Center Beijing University of Chinese MedicineBeijing102488China School of Acupuncture-Moxibustion and Tuina Beijing University of Chinese MedicineBeijing102488China Acupuncture Works LouisvilleKY40205USA

General Secretary Xi Jinping points out“traditional Chinese medicine(TCM)is a treasure of the Chinese nation.We must pro-tect,explore,develop and inherit it well.”According tothe latest in-formation,1 TCM has spread to 196 countries and regions around the world,indicating that it enjoys a good development abroad,especially the development of acupuncture and moxibustion.

关键词： medicine(TCM) acupuncture moxibustion

The development of traditional Chinese medicine

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Journal of Traditional Chinese Medical Sciences 2021年第S1期8卷 1-9页

作者： Danning Ma Shanshan Wang Yu Shi shenglou ni Minke Tang Anlong Xu National Center for TCM International Communication Beijing University of Chinese MedicineBeijing100029China International Exchange and Cooperation Department Beijing University of Chinese MedicineBeijing100029China Periodical Center Beijing University of Chinese MedicineBeijing102488China School of Chinese Materia Medica Beijing University of Chinese MedicineBeijing102488China School of Life Sciences Beijing University of Chinese MedicineBeijing102488China

Similar to other medicines,traditional Chinese medicine(TCM)originated from the need for various practical solutions to treat diseases.It is a knowledge system summarized and condensed by the Chinese nation in the health care practice for thousands of years.TCM continues to serve the health care system.This study summarized the history,health concept,main treatment strategies and methods,current development,and future perspectives of TCM.It may provide a more comprehensive image of the overall TCM system.

关键词： Traditional Chinese medicine Correspondence between universe and man Image thinking History Prospect

Clinical application of Aconitum carmichaelii Debx. (Fu Zi in Chinese) by traditional Chinese medicine physicians–A cross-sectional questionnaire survey in Beijing

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Journal of Traditional Chinese Medical Sciences 2021年第4期8卷 302-308页

作者： Xiaopeng Zhao shenglou ni ning Liang Qiuchen Huang Zhongyi Pan Lin Zhang Jia Song Yanling Fu School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing102488China Periodicals Publishing Center Beijing University of Chinese MedicineBeijing102488China Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing100700China First School of Clinical Medicine Beijing University of Chinese MedicineBeijing100700China

Objective:To investigate clinical application of aconite root(Aconitum carmichaelii Debx.;hereinafter“aconite”)by traditional Chinese medicine(TCM)physicians in TCM hospitals in Beijing and explore the specific use of aconite and the effect of different doses on decoction time.Methods:This was a cross-sectional study using two-stage sampling.Questionnaires were administered among TCM physicians from TCM hospitals in Beijing between September 2020 and August 2021.The questionnaire mainly included general demographics,clinical backgrounds of TCM physicians,and clinical application of aconite.The data analyses were performed using SPSS 20.0.Results:A total of 387 questionnaires were collected,of which 385 were valid.Of the 385 participating TCM physicians,331(85.97%)used aconite in clinical practice.The top three medical diagnoses treated with aconite were heart failure,diarrhea without cause,and chronic gastritis.The TCM pattern treated most frequently with a high dose of aconite was spleen-kidney yang deficiency,and the TCM pattern treated most frequently with a low dose was spleen yang deficiency,while spleen-kidney yang deficiency was treated most frequently with a common dose of aconite.The top three common formulas were Sini decoction,Mahuang Xixin Fuzi decoction,and Zhenwu decoction.Hei Shun Pian was the most common herbal pieces of aconite.The highest frequency of the maximum dose of aconite was 15 g,that of the minimum dose was 3 g,and that of the common dose was 10 g.There was a certain correlation between decoction time and the dose of aconite.Most TCM physicians advised their patients to take medicine twice a day.Conclusion:In this study,we refined and quantified the use of aconite and enriched the exploration of the clinical application of aconite besides its provisions in the Pharmacopoeia of the People's Republic of China.

关键词： Aconite Clinical use Cross-sectional study Two-stage sampling Questionnaire

Characteristics of 240 randomized controlled trials for adjusting constitution in preventive treatment of disease:A bibliometric analysis

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Journal of Traditional Chinese Medical Sciences 2019年第3期6卷 226-233页

作者： Wenjun Yu shenglou ni Qianru Li Mingyue Ma Ya’nan Peng Weidong Yu Hua Jin Pengting Zhang Qi Wang School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing 100029China Periodicals Publishing Center Beijing University of Chinese MedicineBeijing 100029China Wang Jing Hospital of CACMS Beijing 100102China Wellspring TCM Technology Institute Vancouver V5Z2E2Canada Technology and Development Center for TCM of China Beijing 100027China

Background:A growing number of randomized controlled trials(RCTs)have explored the significance of adjusting constitution for preventive treatment of disease in traditional Chinese medicine(TCM).In this study,we sought to comprehensively analyze the characteristics of these RCTs.Methods:All RCTs related to constitutional adjustment and preventive treatment of disease were included in the study.Literature was screened searching seven databases,including Pubmed,Web of Science,Embase,SinoMed,CNKI,Chongqing VIP,and Wangfang Database,from inception to December 2018.Data pertaining to bibliometrics,participants,and interventions were extracted and analyzed.Results:Two hundred and forty papers were published between 2007 and 2018,involving 240 RCTs with 55977 total participants.Sample size in these RCTs ranged from 30 to 7800.Among them,59 RCTs addressed disease prevention prior to onset involving 11 healthy states of participants,mainly for general health or sub-health population(40.68%)using health care and non-drug therapy.In control the development of existing disease(n Z 174),59 diseases were involved.Based on the number of RCTs and sample sizes,diseases including type 2 diabetes mellitus,primary hypertension,nonalcoholic fatty liver disease,and hyperlipoproteinemia accounted for 51.15%of the total patients studied.Drug therapy as an intervention was frequently used.In preventing recurrence after recovery(n Z 7),over 4 kinds of health status in participants were involved.Drug therapy combined with health care was mostly used.Most RCTs reported positive outcomes,with only one reporting negative findings(1/240).Conclusion:The number of RCTs of constitutional adjustment on preventive treatment of disease has gradually increased since 2012.Participants and intervention measures from the above-mentioned types of RCTs exhibit their own characteristics.Future systematic reviews or meta-analyses on constitutional adjustment for preventive treatment of disease are warranted.

关键词： Traditional Chinese medicine constitution Constitutional adjustment Preventive treatment of disease Randomized controlled trials Bibliometrics

Epidemiological survey on prevalence and associated risk factors of bitter taste among inpatients from four Grade 3A hospitals in Beijing

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Journal of Traditional Chinese Medical Sciences 2017年第1期4卷 31-38页

作者： Pengfei Si Yanling Fu shenglou ni Xun Ma Xinrong Wang Qian Du Chao Wang School of Basic Medical Sciences Beijing University of Chinese MedicineBeijing 100029China

Objective:To study the possible etiology of bitter taste in the mouth and its diagnostic significance by an epidemiological survey on its associated diseases and influence factors.Methods:A cross-sectional epidemiological study was conducted by recruiting patients from four Grade 3A hospitals in Beijing.The questionnaire incorporated five aspects i.***.general information,gustation,behavior,symptomology and past medical history.SPSS20.0 software package was used for data analysis.T-test and chi-square test were selected for evaluation.An observation of the correlation between different causative factors and the symptoms of bitter taste was analyzed by Logistic regression.Results:Smoking and excessive consumption of meat and emotional stress were the risk factors,while eating fresh fruits and vegetables were key protective elements against the manifestation of bitter taste in the mouth.The incidence of bitter taste was high in patients suffering from gastroesophageal disease,hepatic and gallbladder diseases and neurological diseases.Conclusion:Bitter taste is a common symptom in hospitalized patients,especially in patients with gastroesophageal reflux and liver and gallbladder diseases and the link to smoking,dietary and emotional stress.It is found that smoking is a sole risk factor for the manifestation of bitter taste.

关键词： Bitter taste Influence factor Epidemiology Cross-sectional study

Effects of Zingiber officinalis (WILLD.)ROSC.Membranes on minor recurrent aphthous stomatitis: a randomized pragmatic trial

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Journal of Traditional Chinese Medical Sciences 2018年第1期5卷 58-63页

作者： Qian Du shenglou ni Lin Guo Wenjie Song Kun Zhao ni Liu Xinrong Wang Xun Ma Yanling Fu Quanming Tan Beijing University of Chinese Medicine Beijing 100029China Singapore Thong Chai Medical Institution Thong Chai Building 169874Singapore

Objective:To evaluate the effects of dried ginger rhizome (DGR;Zingiber officinalis (WILLD.) ROSC.),prepared as a membrane,in minor recurrent aphthous stomatitis (miRAS)treatment and explore its mechanism of action by detecting changes in levels of epidermal growth factor (EGF) and tumor necrosis factor (TNF)-α in saliva.Methods:Fifty-nine miRAS patients were enrolled in this study.The number of participants in the dried ginger rhizome membrane (DGRM) group was 30,and 29 were in the placebo membrane (PM) group.Sixty sealed envelopes containing either type of membrane were coded randomly.Investigators and participants were blinded to group assignments.A visual analog scale (VAS) was used for pain,follow-up information for healing time,and enzyme-linked immunosorbent assays to measure the concentrations of EGF and TNF-α.Results:In terms of VAS,there was a significant difference between pre-and post-DGRM treatment (P .05).A significant difference was observed in the healing time between the two groups (6.08 (2.712) vs.8.04 (2.142) days).The mean healing time in the DGRM group was shorter than that in the PM group (P nificantly after treatment (P nificantly lower than that in the PM group (P nificantly after treatment (P nificantly lower level than that in the PM group (P ning of healing time,reducing the EGF level in saliva,and has an inhibitory effect on TNF-α release.

关键词： Dried ginger rhizome membrane Recurrent aphthous stomatitis Epidermal growth factor Tumor necrosis factor-α

《小品方》方药服量控制策略与服药方法的文献研究

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中医杂志 2022年第15期63卷 1479-1483页

作者：刘旎倪胜楼张林傅延龄潘中艺北京中医药大学中医学院北京市102446 北京中医药大学期刊中心

目的探析陈延之《小品方》中方药服量的控制策略与方法。方法纳入《小品方》中方名、主治病症、药物组成、方药剂量及煎服法均完整辑录的内服方剂,并运用描述性分析对所纳入的数据进行频次统计与归纳总结。结果共纳入内服方剂194首。汤... 详细信息

目的探析陈延之《小品方》中方药服量的控制策略与方法。方法纳入《小品方》中方名、主治病症、药物组成、方药剂量及煎服法均完整辑录的内服方剂,并运用描述性分析对所纳入的数据进行频次统计与归纳总结。结果共纳入内服方剂194首。汤剂单次服量为30~1200 ml,以300 ml最多见,约占汤剂单次服量总频次的46.19%。散剂单次服量为0.10~15 g,以5 g最多见,约占散剂单次服量总频次的64.29%。丸剂单次服量为0.02~6 g,以2 g最多见,约占丸剂单次服量总频次的34%。服药次数为2日1服~日7服,各剂型均以日服3次最为常见,约占3种剂型日服次数总频次的68.15%。服药时间以定时服药为主,但据病情轻重、病理特点与人体生物节律等不同,有汤剂顿服、平旦服药及昼夜连服等特殊服法。结论《小品方》强调多因素综合作用下机体对于药物耐受性与敏感性的差异是决定服量轻重的关键。其通过对方药的单次服量及服药间隔时间的调整,增强了服法对于方药绝对服量的控制。

关键词：药物服量《小品方》个性化治疗精准治疗

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张仲景医学源流述略

北京中医药大学学报 2018年第11期41卷 894-899页

作者：潘中艺傅延龄宋佳倪胜楼中国五矿集团有限公司北京100010 北京中医药大学

张仲景医学在中医学术发展史上具有非同一般的地位及影响,自古至今习医之人莫不从中汲取养分,想要研究仲景医学,首先应弄清其源流及发展脉络。本文从仲景医学之"源"、仲景医学之"诞生"以及仲景医学之"流"三方面进行梳理,认为仲景医学之"... 详细信息

张仲景医学在中医学术发展史上具有非同一般的地位及影响,自古至今习医之人莫不从中汲取养分,想要研究仲景医学,首先应弄清其源流及发展脉络。本文从仲景医学之"源"、仲景医学之"诞生"以及仲景医学之"流"三方面进行梳理,认为仲景医学之"源"有上古时期的三世医学与春秋战国时期的四家医学;仲景医学之"诞生"则是熔医经与经方于一炉,并使中医辨证论治各环节贯通一体;仲景医学之"流"则主要体现在1 800年间伤寒学派的不断发展,对其他医学分科和流派的重要影响,以及在海外的传播与变化。

关键词：张仲景医学伤寒论源流经方流派

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《金匮要略》橘枳姜汤异文考

天津中医药 2023年第2期40卷 169-173页

作者：李楠孟庆鸿倪胜楼陈泽霖曾凤中国中医科学院研究生院北京100700 北京中医药大学北京100029

在《金匮要略》等5种中医古籍中,橘枳姜汤的方证、药量、药用单位存在诸多差异。文章融合版本学、文字学以及中医理法方药的研究方法,对各书异文进行全面考证,提出:橘枳姜汤的方证包括胸中证、咽喉证、口中证,胸中证表现为胸中气塞,甚... 详细信息

在《金匮要略》等5种中医古籍中,橘枳姜汤的方证、药量、药用单位存在诸多差异。文章融合版本学、文字学以及中医理法方药的研究方法,对各书异文进行全面考证,提出:橘枳姜汤的方证包括胸中证、咽喉证、口中证,胸中证表现为胸中气塞,甚者有胀满之感,同时可兼有短气;咽喉证表现为噎塞,咽喉部的痒与干涩;口中证表现为燥唾,吐涎沫,其中又以“胸中气塞”为核心。药量以“橘皮一斤,枳实三两,生姜半斤”最为可靠。根据古今度量衡折算标准及方后煎服法,从古代文献角度为本方的现代应用提供用量参考:陈皮110 g,枳实21 g,生姜55 g。橘枳姜汤错综复杂的异文现象,显示了传世方书文本的复杂性和不确定性。应扎实做好文字辨析、医理推敲、判断取舍的文本考释,为临床应用及相关研究提供有益的参考。

关键词：金匮要略宋校医书橘枳姜汤文献考证

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黄柏历代临床用量分析

中医杂志 2014年第13期55卷 1142-1145页

作者：陈传蓉李必刚张林倪胜楼傅延龄北京中医药大学基础医学院湖北省长阳县中医院北京中医药大学继续教育学院

目的总结黄柏从汉代至今的临床用量特点。方法采用Excel表建立历代黄柏剂量数据库，选取各朝代最具代表性的医学著作，录入含有黄柏方剂的方名、总药量、黄柏药量、整方药味数、加水量、服法等。统计黄柏出现的频次、最常用量、常用量... 详细信息

目的总结黄柏从汉代至今的临床用量特点。方法采用Excel表建立历代黄柏剂量数据库，选取各朝代最具代表性的医学著作，录入含有黄柏方剂的方名、总药量、黄柏药量、整方药味数、加水量、服法等。统计黄柏出现的频次、最常用量、常用量上限、常用量下限、最大用量、最小用量、平均用量，并结合文献分析历代黄柏用量特点。结果历代黄柏用量规律大致为汉唐时期用量最大，唐代每方用量最高可达220g；至宋代仍然维持着较大剂量，常用剂量范围为8～40g；但从金元至近代、当代，其用量大幅下降，每方最大量在30g左右。结论黄柏汉唐时期用量最大，金元至当代用量大幅下降。

关键词：黄柏临床用量文献研究