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Tsinghua Science and Technology 2024年第4期29卷 971-984页

作者： Yuze Peng shengjun xu Qingkun Chen Wenjin Huang Yihua Huang School of Electronics and Information Technology Sun Yat-sen UniversityGuangzhou 510006China Guangdong Provincial Key Laboratory of Optoelectronic Information Processing Chips and Systems Sun Yat-sen UniversityGuangzhou 510006Chinaand Southern Marine Science and Engineering Guangdong LaboratoryZhuhai 519080China

Popularity plays a significant role in the recommendation system. Traditional popularity is only defined as a static ratio or metric (e.g., a ratio of users who have rated the item and the box office of a movie) regardless of the previous trends of this ratio or metric and the attribute diversity of items. To solve this problem and reach accurate popularity, we creatively propose to extract the popularity of an item according to the Proportional Integral Differential (PID) idea. Specifically, Integral (I) integrates a physical quantity over a time window, which agrees with the fact that determining the attributes of items also requires a long-term observation. The Differential (D) emphasizes an incremental change of a physical quantity over time, which coincidentally caters to a trend. Moreover, in the Session-Based Recommendation (SBR) community, many methods extract session interests without considering the impact of popularity on interest, leading to suboptimal recommendation results. To further improve recommendation performance, we propose a novel strategy that leverages popularity to enhance the session interest (popularity-aware interest). The proposed popularity by PID is further used to construct the popularity-aware interest, which consistently improves the recommendation performance of the main models in the SBR community. For STAMP, SRGNN, GCSAN, and TAGNN, on Yoochoose1/64, the metric P@20 is relatively improved by 0.93%, 1.84%, 2.02%, and 2.53%, respectively, and MRR@20 is relatively improved by 3.74%, 1.23%, 2.72%, and 3.48%, respectively. On Movieslen-1m, the relative improvements of P@20 are 7.41%, 15.52%, 8.20%, and 20.12%, respectively, and that of MRR@20 are 2.34%, 12.41%, 20.34%, and 19.21%, respectively.

关键词： popularity Proportional Integral Differential(PID) algorithm session-based recommendation user’s interests

Microbial community structure analyses and cultivable denitrifier isolation of Myriophyllum aquaticum constructed wetland under low C/N ratio

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Journal of Environmental Sciences 2023年第5期127卷 30-41页

作者： Jialiang Zuo Lina xu Jianlin Guo shengjun xu Shuanglong Ma Cancan Jiang Dongmin Yang Danhua Wang xuliang Zhuang Key Laboratory of Environmental Biotechnology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China Sino-Danish Center University of Chinese Academy of SciencesBeijing 101408China Institute of Tibetan Plateau Research Chinese Academy of SciencesBeijing 100101China College of Resources and Environmental Sciences Henan Agricultural UniversityZhengzhou 450002China Ningxia Zhongke Jingke Testing Technology Company Yinchuan 750000China

With the rapid expansion of livestock production,the amount of livestock wastewater accumulated *** of biodegradable organic matter makes denitrification of livestock wastewater after anaerobic digestion more *** this study,Myriophyllum aquaticum constructed wetlands(CWs)with efficient nitrogen removal performance were established under different carbon/nitrogen(C/N)*** of community composition reveals the change of *** CWs in microbial community structure with C/N *** proportion of Proteobacteria which is one of the dominant phyla among denitrifier communities increased significantly under low C/N ratio ***,to obtain cultivable denitrifier that could be added into CWs in situ,33 strains belonging to phylum Proteobacteria were isolated from efficient *** CWs,while the best-performing denitrification strain M3-1 was identified as Bacillus velezensis JT3-1(GenBank ***032506.1).Redundancy analysis and quadratic models showed that C/N ratio had significant effects on disposal of nitrate(NO_(3)^(−)-N)and the strains isolated could perform well in denitrification when C/N ratio is relatively *** addition,they have relatively wide ranges of carbon sources,temperature and a high NO_(3)^(−)removal rate of 9.12 mg/(L·hr)at elevated concentrations of 800 mg/L ***,strains isolated from *** CWs with low C/N ratio have a practical application value in the treatment of nitrate-containing *** denitrifying bacteria could be added to CWs to enhance nitrogen removal efficiency of CWs for livestock wastewater with low C/N ratio in the future.

关键词： Myriophyllum aquaticum constructed wetlands Denitrification Microbial community structure Bacillus velezensis

Clinical challenges and research perspectives in liver transplant oncology

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中华医学杂志(英文版) 2024年第22期137卷 2651页

作者： xu shengjun Shu Wenzhi He Xinyu Ling Sunbin Wei xuyong xu Xiao NHFPC Key Laboratory of Combined Multi-Organ Transplantation Institute of Organ Transplantation Zhejiang University Hangzhou Zhejiang China Center of Hepatobiliary Pancreatic Disease Beijing Tsinghua Changgung Hospital School of Clinical Medicine Tsinghua University Beijing China The Fourth School of Clinical Medicine Zhejiang Chinese Medical University Hangzhou Zhejiang China School of Clinical Medicine Hangzhou Medical College Hangzhou Zhejiang China Institute of Translational Medicine Zhejiang University Hangzhou Zhejiang China

[...]balancing potential clinical benefits and donor liver scarcity remains the primary concern.[...]the current clinical challenges in liver transplant oncology can be summarized and categorized into the following five facets: optimal candidate selection criteria, pre-transplant oncological management, intra-transplant reasonable surgical procedures, individualized immunosuppressive regimen, and clinical strategies for tumor recurrences and DNMs.Various modalities for bridging/downstaging, including locoregional and systemic therapies, are available for this purpose, and the choice of modality depends on factors, including tumor burden, tumor location, liver function, financial status, as well as the experience and preference of medical centers.Recent studies have focused on the gut flora–graft rejection relationship, using 16S rRNA next-generation sequencing to analyze the differences in flora between rejection and non-rejection groups.Hepatic ischemic reperfusion injury, during surgical procedure, is a sterile injury and has been proven to result in intestinal congestion, thus leading to the translocation of intestine bacterial into the portal vein to promote cancer recurrence.

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Effect of Trichoderma viride biofertilizer on ammonia volatilization from an alkaline soil in Northern China

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Journal of Environmental Sciences 2018年第4期30卷 199-207页

作者： Xia Wang shengjun xu Shanghua Wu Shugeng Feng Zhihui Bai Guoqiang Zhuang xuliang Zhuang School of Life Sciences University of Science and Technology of China CAS Key Laboratory of Environmental Biotechnology Research Center for Eco-Environmental Science Chinese Academy of Sciences College of Resources and Environment University of Chinese Academy of Sciences

Ammonia（NH3） volatilization is one of the primary pathways of nitrogen（N） loss from soils after chemical fertilizer is applied, especially from the alkaline soils in Northern China, which results in lower efficiency for chemical fertilizers. Therefore, we conducted an incubation experiment using an alkaline soil from Tianjin（p H 8.37–8.43） to evaluate the suppression effect of Trichoderma viride（T. viride） biofertilizer on NH3 volatilization, and compared the differences in microbial community structure among all samples. The results showed that viable T. viride biofertilizer（T） decreased NH3 volatilization by 42.21% compared with conventional fertilizer（（CK）, urea）, while nonviable T. viride biofertilizer（TS） decreased NH3 volatilization by 32.42%. NH3 volatilization was significantly higher in CK and sweet potato starch wastewater（SPSW） treatments during the peak period. T. viride biofertilizer also improved the transfer of ammonium from soil to sweet sorghum. Plant dry weights increased 91.23% and 61.08% for T and TS, respectively, compared to CK. Moreover, T. viride biofertilizer enhanced nitrification by increasing the abundance of ammonium-oxidizing archaea（AOA） and ammonium-oxidizing bacteria（AOB）. The results of high-throughput sequencing indicated that the microbial community structure and composition were significantly changed by the application of T. viride biofertilizer. This study demonstrated the immense potential of T. viride biofertilizer in reducing NH3 volatilization from alkaline soil and simultaneously improving the utilization of fertilizer N by sweet sorghum.

关键词： Alkaline soil Ammonia volatilization Trichoderma viride biofertilizer Functional gene Microbial community

Ecological selection of bacterial taxa with larger genome sizes in response to polycyclic aromatic hydrocarbons stress

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Journal of Environmental Sciences 2022年第2期34卷 82-93页

作者： Yuzhu Dong Shanghua Wu Haonan Fan Xianglong Li Yijing Li shengjun xu Zhihui Bai xuliang Zhuang Key Laboratory of Environmental Biotechnology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China College of Resources and Environment University of Chinese Academy of SciencesBeijing 200049China College of Sino-Danish Center University of Chinese Academy of SciencesBeijing 100049China

Polycyclic aromatic hydrocarbons(PAHs)are ubiquitous priority pollutants that cause great damage to the natural environment and *** genome size in a community is critical for shedding light on microbiome's functional response to pollution stress within an ***,microcosms under different concentrations were performed to evaluate the selection of PAHs stress on the average genome size in a *** found the distinct communities of significantly larger genome size with the increase of PAHs concentration gradients in soils,and consistent trends were discovered in soils at different *** abundance of Proteobacteria and Deinococcus-Thermus with relatively larger genomes increased along with PAHs stress and well adapted to polluted *** contrast,the abundance of Patescibacteria with a highly streamlined and smaller genome decreased,implying complex interactions between environmental selection and functional fitness resulted in bacteria with larger genomes becoming more ***,we confirmed the increased capacity for horizontal transfer of degrading genes between communities by showing an increased connection number per node positively related to the nid A gene along the concentration gradients in the co-occurrence *** findings suggest PAHs tend to select bacterial taxa with larger genome sizes,with significant consequences for community stability and potential biodegradation strategies.

关键词： Pollution stress Polycyclic aromatic hydrocarbons(PAHs) Genome size Horizontal gene transfer Soil microbial community

Effective removal of antibiotic resistance genes and potential links with archaeal communities during vacuum-type composting and positive-pressure composting

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Journal of Environmental Sciences 2020年第3期32卷 277-286页

作者： Haonan Fan Shanghua Wu John Woodley Guoqiang Zhuang Zhihui Bai shengjun xu xuan Wang xuliang Zhuang Key Laboratory of Environmental Biotechnology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China College of Resources and Environment University of Chinese Academy of SciencesBeijing 100049China Key Laboratory of Agricultural Water Resources Center for Agricultural Resources ResearchInstitute of Genetic and Developmental BiologyChinese Academy of SciencesShijiazhuang 050021China Center for Process Engineering and Technology Department of Chemical and Biochemical EngineeringTechnical University of DenmarkDK-2800 Kgs.LyngbyDenmark

As a major reservoir of antibiotics,animal manure contributes a lot to the augmented environmental pressure of antibiotic resistance genes(ARGs).This might be the first study to explore the effects of different ventilation types on the control of ARGs and to identify the relationships between archaeal communities and ARGs during the composting of dairy *** ARGs were quantified via Real-time qPCR and microbial communities including bacteria and archaea were analyzed by High-throughput sequencing during vacuum-type composting(VTC) and positive-pressure composting(PPC).The total detected ARGs and class I integrase gene(intI1) under VTC were significantly lower than that under PPC during each stage of the composting(p <0.001).The relative abundance of potential human pathogenic bacteria(HPB) which were identified based on sequencing information and correlation analysis decreased by 74.6% and 91.4% at the end of PPC and VTC,*** composition of archaeal communities indicated that methane-producing archaea including Methanobrevibacter,Methanocorpusculum and Methanosphaera were dominant throughout the *** analysis suggested that Methanobrevibacter and Methanocorpusculum were positively correlated with all of the detected *** analysis determined that the possible hosts of ARGs were different under VTC and PPC,and provided new sights about potential links between archaea and *** results showed better performance of VTC in reducing ARGs and potential HPB and demonstrated that some archaea could also be influential hosts of ARGs,and caution the risks of archaea carrying ARGs.

关键词： Antibiotic resistance genes(ARGs) Composting Archaea Human pathogenic bacteria Bacterial communities

Enhanced nitrogen removal of the anaerobic ammonia oxidation process by coupling with an efficient nitrate reducing bacterium(Bacillus velezensis M3-1)

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Journal of Environmental Sciences 2024年第12期146卷 3-14页

作者： Wanlian Yuan Dongmin Yang xupo Zhang Cancan Jiang Danhua Wang Jialiang Zuo shengjun xu xuliang Zhuang School of Life Sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230027China Key Laboratory of Environmental Biotechnology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China College of Resources and Environment University of Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Tibetan Plateau Earth System Environment and Resources(TPESER)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China

Bacillus velezensis M3-1 strain isolated from the sediment of Myriophyllum aquatium con-structedwetlandswas found to efficiently convert NO_(3)^(-)-N to NO_(2)^(−)-N,and the requirements for carbon source additionwere not very *** demonstrates,for the first time,the feasibility of using the synergy of anammox and Bacillus velezensis M3-1 microorganisms for nitrogen *** this study,the possibility of M3-1 that converted NO_(3)^(−)-N produced by anammox to NO_(2)^(−)-N was verified in an anaerobic *** NO_(3)^(−)-N reduction ability of M3-1 and denitrifying bacteria in coupling system was investigated under different C/N conditions,and it was found that M3-1 used carbon sources preferentially over denitrifying *** adjusting the ratio of NH4+-N to NO_(2)^(−)-N,it was found that the NO_(2)^(−)-N con-verted from NO_(3)^(−)-N by M3-1 participated in the original *** nitrogen removal efficacy(NRE)of the coupled system was increased by 12.1%,compared to the control group anammox system at C/N=2:*** gene indicated that itmight be a nitrate reducing *** study shows that the nitrate reduction rate achieved by the Bacillus velezensis M3-1 can be high enough for removing nitrate produced by anammox process,which would enable improve nitrogen removal from wastewater.

关键词： Bacillus velezensis M3-1 Anammox Denitrifying bacteria C/N Nitrogen removal efficacy Functional gene abundance

Dual-additives enable stable electrode-electrolyte interfaces for long life Li-SPAN batteries

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Chinese Chemical Letters 2024年第5期35卷 459-465页

作者： Zhenqiang Guo Huicong Yang Qian Wei shengjun xu Guangjian Hu Shuo Bai Feng Li School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Department of Biochemistry and Molecular Biology College of Life ScienceChina Medical UniversityShenyang 110122China Dalian National Laboratory for Clean Energy Dalian 116023China Shenyang King Power Technology Co. Ltd.Shenyang 110016China

Sulfurized polyacrylonitrile(SPAN)is proposed as a promising cathode material for lithium sulfur ***,the continuous side reactions at the electrolyte-electrode interfaces as well as the slow redox kinetics of SPAN cathode deteriorate the electrochemical *** this study,an electrolyte with dual-additives comprising 2-fluoropyridine(2-FP)and lithium difluorobis(oxalato)phosphate(LiDFBOP)was used to improve the performance of Li||SPAN cells.2-FP has a lower lowest occupied molecular orbital energy than that of the solvents in the electrolyte,leading to its prior reduction.A LiF-rich film can be formed on the electrode,effectively improving the stability of the electrolyte-electrode interfaces and prolonging the ***,LiDFBOP could form an electrolyte-electrode interface film containing a large amount of Li_(x)PO_(y)F_(z) species,compensating for the kinetic deterioration caused by the lower ionic conductive of LiF formed at the electrolyte-electrode ***,an electrode-interface film with good chemical stability and high Li^(+) transport was established by LiF and Li_(x)PO_(y)F_(z)-rich *** Li||SPAN cell with the electrolyte containing dual-additives demonstrates an excellent capacity retention of 97.5%after 200 cycles at 1.0 C,25℃,comparing to 56.2%capacity retention without ***,the rate capacities of cells with dual-additives can reach 1128.1 mAh/g at 5 C,comparing to only 813.5 mAh/g using electrolyte without *** results shown that the dual-additives in electrolyte provide a promising strategy for practical application of lithium sulfur batteries with SPAN cathodes.

关键词： Sulfurized polyacrylonitrile Lithium metal Interface film 2-Fluoropyridine Difluorobis(oxalato)phosphate

Aerobic Alcohol Ammoxidation Catalyzed by Copper（I）/Amino Acid： a Scalable Protocol to Nitriles

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Chemical Research in Chinese Universities 2016年第4期32卷 586-593页

作者： ZHANG Guofu ZHANG Guihua LEI Jie LI Shasha xu shengjun DING Chengrong SHAN Shang College of Chemical Engineering Zhejiang University of Technology Hangzhou 310014 P. R. China

A facile, practical and scalable catalyst system for alcohols ammoxidation into nitriles was developed using amino acid as ligand, oxygen as terminal oxidant and copper iodide（CuI） as catalyst. The catalyst system shows excellent functional groups compatibility for a wide range of testing substrates, even the substrates bearing oxidationsensitive groups such as MeS-, alkenyl and --NH2 can also work well. In addition, the protocol is readily scaled up to more than 20 g and the product can be obtained just through filtration or distillation without conventional column chromatography.

关键词： Alcohol Amino acid Nitrile Copper iodide Scale up