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Peroxisome proliferator-activated receptor gamma mutation in familial partial lipodystrophy type three:A case report and review of literature

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World Journal of Diabetes 2024年第12期15卷 2360-2369页

作者： Chao-Jun Wu hao Liu Li-Juan tu Jiong-Yu Hu Basic Medical College Army Medical UniversityChongqing 400038China Department of Endocrinology Rare Disease CenterThe First Affiliated Hospital of Army Medical UniversityChongqing 400038China

BACKGROUND Familial partial lipodystrophy disease(FPLD)is a collection of rare genetic diseases featuring partial loss of adipose ***,metabolic difficulties,such as severe insulin resistance,diabetes,hypertriglyceridemia,and hyperte-nsion frequently occur alongside adipose tissue loss,making it susceptible misdiagnosis and delaying effective *** genes are implicated the occurrence of FPLD,and genetic testing has been for conditions linked single gene mutation related to *** recent reports,treatment of the disease is limited to preventing and improving complications in *** 2017,a 31-year-old woman with diabetes,hypertension and hypertriglyceri-demia was *** identified a mutation in her peroxisome proliferator-activated receptor gamma(PPARG)gene,Y151C(***151Cys),which results in a nucleotide substitution residue 452 in the DNA-binding domain(DBD)of *** unaffected family member did not carry this ***,a PPARG agonist,improved the patient’s responsiveness to hypoglycemic and antihyper-tensive *** one year of treatment in our hospital,the fasting blood glucose and glycosylated hemoglobin of the patient were close to normal.

关键词： Familial partial lipodystrophy Peroxisome proliferator-activated receptor gamma Tyr151Cys Phenotypic he-terogeneity Case report

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雷公藤治疗类风湿关节炎的困境与对策

中国中西医结合杂志 2009年第2期29卷 104-105页

作者：涂胜豪华中科技大学同济医学院附属同济医院中医科

对类风湿关节炎疗效最为突出的中药首推雷公藤, 最早记载雷公藤功效的是公元1476年明朝兰茂所著的, 书中称其"味辛, 性温, 有毒.

关键词：类风湿关节炎雷公藤制剂筋骨疼痛抑制作用十二经络类风湿因子中药复方《滇南本草》中药不良反应风寒湿痹

QUASI-SYNCHRONOUS MULTICARRIER DS-CDMA USING Z-COMPLEMENTARY SEQUENCES

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Journal of Electronics(China) 2009年第4期26卷 487-491页

作者： tu Yifeng Fan Pingzhi Yuan Weina hao Li Provincial Key Lab of Information Coding ＆ Transmission Institute of Mobile Communications Southwest Jiaotong University Chengdu 510031 China School of Information Science ＆ Engineering East China University of Science ＆ Technology Shanghai 200092 China

In this paper, a multicarrier DS-CDMA system which employs Z-Complementary Se- quences (ZCS) as spreading code is investigated. The new system can not only eliminate multipath interference and Multiple Access Interference (MAI), but also support flexible number of users com- pared with system using Orthogonal Complementary (OC) codes. Multicarrier DS-CDMA using OC codes can be regarded as a special case of our proposed system. Zero Correlation Zone (ZCZ) of ZCS can be flexibly adjusted to meet the requirements on the user number and maximum multipath and in- ter-user delay, in this way, more users can be supported without losing interference-free property. The effectiveness of the proposed system is validated through theoretical analysis and simulation results.

关键词： Orthogonal Complementary (OC) codes Multicarrier DS-CDMA Z-Complemen-tary Sequences (ZCS) Zero Correlation Zone (ZCZ)

Synthesis and Electrochemical Characterization of Azomethine Containing N-Ethylcarbazole Group

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Chemical Research in Chinese Universities 2005年第6期21卷 743-748页

作者： LI Ya-peng SUN Li-min SUN Ming-hao LI Hong-tu ZHANG Hong-wen WANG Jing-yuan College of Chemistry The First Medical College Jilin University Changchun 130023 P. R. China

Conjugated aromatic azomethines containing a carbazole group were synthesized. Their structures have been confirmed by IR, MS and UV spectrometries. When iodine was used as the dope to the conjugated compounds, the electrical conductivities （EC） of the doped conjugated compounds were increased by several orders of magnitude. The thermal stability of these two compounds investigated by TGA shows a good result, which guarantees the correct result of EC when the compounds are heated. As can be seen from the CV characterization of the electrochemical properties of these two compounds, the azomethine diamine and p-aminophenyl-9-ethylcarbazolyl azomethine possess electrochemical activity, which arises from the heteroatom of molecules.

关键词： Azomethine Carbazole Conjugated compound Electrochemical activity Doped material

Effect of renal denervation for patients with isolated systolic hypertension:a systematic review and meta-analysis

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Journal of Geriatric Cardiology 2023年第2期20卷 121-129页

作者： Le LI Yu-Long XIONG Bin tu Shang-Yu LIU Zhen-hao ZHANG Zhao HU Yan YAO Department of Cardiology Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

BACKGROUND Renal denervation(RDN)is a promising treatment based on catheter intervention for patients with refractory ***,the effect in patients with isolated systolic hypertension(ISH)remains *** aim of this meta-analysis was to determine the blood pressure lowing effect of RDN in patients with ISH compared with combined systolic/diastolic hypertension(CH)*** PubMed,Embase,Cochrane and *** were searched for prospective clinical studies that included *** outcomes of interest were the change of 24-hour ambulatory systolic blood pressure(SBP)from *** used the fixed effects model to calculate weighted mean difference(WMD)with 95%confidence interval(CI).RESULTS Six trials were included,with 1405 participants,including 597 patients with ISH and 808 patients with *** follow-up was five *** reduction of 24-hour ambulatory SBP was significantly greater for the CH patients than the ISH patients(WMD=3.89,95%CI:2.32–5.45,P<0.0001).RDN also showed a greater reduction in office SBP in the CH patients compared to the ISH patients(WMD=10.24,95%CI:4.24–15.74,P=0.0003).And the effect was independent of age,length of follow-up,and ablation *** RDN provides superior blood pressure control in the CH patients compared with the ISH patients,and the CH patients may be the best suitable population for which RDN is indicated.

关键词： patients hypertension systolic

Plasma-enhanced catalytic activation of CO_(2) in a modified gliding arc reactor

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Waste Disposal and Sustainable Energy 2020年第2期2卷 139-150页

作者： hao Zhang Li Li Ruiyang Xu Jingying Huang Ni Wang Xiaodong Li Xin tu State Key Laboratory of Clean Energy Utilization Zhejiang UniversityHangzhou 310027China Department of Electrical Engineering and Electronics University of LiverpoolLiverpool L693GJUK

For the first time,this paper demonstrates a synergistic effect from the combination of a gliding arc discharge plasma with a photocatalyst TiO_(2) for CO_(2) *** effects of adding a tray downstream the discharge and the combination of the catalyst with plasma have been *** different combination modes of plasma catalysis,i.e.,in-plasma catalysis and post-plasma catalysis,have been evaluated with the emphasis on the analysis of potential *** results show that modifying the gliding arc reactor by the addition of a tray can enhance the fraction of gas treated by plasma,thus improv-ing the reaction *** exceptional synergistic effect of combining the gliding arc discharge with TiO_(2) for CO_(2) activation forms in the in-plasma catalysis *** presence of TiO_(2) significantly enhances the CO_(2) conversion by 138% and the energy efficiency by 133%at a flow rate of 2 L/*** plasma activation effect,which produces energetic electrons that can create the electron-hole pairs on the catalyst surface,is believed to be the major contributor to the generation of the plasma catalysis *** mechanism has been further evidenced by the negligible influence of the post-plasma catalysis on the reaction performance.

关键词： CO_(2)activation Plasma catalysis TiO_(2) Synergistic effect

Complexation extraction of scheelite and transformation behaviour of tungsten-containing phase using H_(2)SO_(4) solution with H_(2)C_(2)O_(4) as complexing agent

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Transactions of Nonferrous Metals Society of China 2021年第10期31卷 3150-3161页

作者： Qing-sheng LIU Tao tu hao GUO Hua-jin CHENG Xue-zhong WANG Faculty of Materials Metallurgy and Chemistry Jiangxi University of Science and TechnologyGanzhou 341000China Mechanical and Electrical Engineering Department Gannan University of Science and TechnologyGanzhou 341000China School of Materials Science and Engineering Jiangsu UniversityZhenjiang 212013China

The extraction of tungsten from scheelite was carried out using a sulfuric acid solution with oxalic acid as the chelating *** was obtained in the form of highly soluble hydrogen aqua oxalato tungstate H_(2)[WO_(3)(C_(2)O_(4))·H_(2)O] during the leaching process,while calcium remained in the residue as calcium sulfate dihydrate(CaSO4·2H2O).About 99.2%of the tungsten was leached at 70℃,1.5 mol/L sulfuric acid,1 mol/L oxalic acid,a liquid/solid ratio of 25:1(mL/g),an oxalic acid to sulfuric acid molar ratio of 1:1,a stirring speed of 300 r/min and a leaching time of 2 h.H_(2)[WO_(3)(C_(2)O_(4))·H_(2)O]was thermally decomposed into tungstic acid(H_(2)WO_(4)),and tungsten trioxide(WO_(3))was directly produced by calcining H_(2)WO_(4) at 700℃ for 2 *** surface chemical reaction was determined to be the controlling step during tungsten leaching,and the apparent activation energy was calculated to be 51.43 kJ/mol.

关键词： scheelite kinetics chemical reaction oxalic acid sulfuric acid

An Image Encryption Method Based on Bit Plane Hiding Technology

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Wuhan University Journal of Natural Sciences 2006年第5期11卷 1283-1286页

作者： LIU Bin LI Zhitang tu hao Network and Computing Center Huazhong Universityof Science and Technology Wuhan 430074 Hubei China

A novel image hiding method based on the correlation analysis of bit plane is described in this paper. Firstly, based on the correlation analysis, different bit plane of a secret image is hided in different bit plane of several different open images. And then a new hiding image is acquired by a nesting ＂Exclusive-OR＂ operation on those images obtained from the first step. At last, by employing image fusion technique, the final hiding result is achieved. The experimental result shows that the method proposed in this paper is effec rive.

关键词： image hiding image fusion bit plane correlation analysis

Forging Inspired Processing of Sodium-Fluorinated Graphene Composite as Dendrite-Free Anode for Long-Life Na–CO_(2) Cells

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Energy & Environmental Materials 2022年第2期5卷 572-581页

作者： Yangjun Mao Xiao Chen hao Cheng Yunhao Lu Jian Xie Tao Zhang Jian tu Xiongwen Xu Tiejun Zhu Xinbing Zhao State Key Laboratory of Silicon Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou 310027China Department of Physics Zhejiang UniversityHangzhou 310027China State Key Lab of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050China LI-FUN Technology Corporation Limited Zhuzhou 412000China

Na–CO_(2) batteries recently are emerging as promising energy-storage devices due to the abundance of Na in the earth’s crust and the clean utilization of greenhouse gas CO_(2) .However,similar to metallic Li,metallic Na also suffers from a serious issue of dendrite growth upon repeated cycling,while a facile method to solve this issue is still *** this work,we report an effective,environmentally friendly method to inhibit Na dendrite growth by in situ constructing a stable,NaF-rich solid electrolyte interface(SEI)layer on metallic Na via adding a small amount(~3 wt%)of fluorinated graphene(FG)in bulk *** by the forging processing,a uniform Na/FG composite was obtained by melting and repetitive FG-adsorbing/hammering *** Na/FG–Na/FG half cell exhibits a low voltage hysteresis of 110–140 mV over 700 h at a current density up to 5 mA cm^(-2) with an areal capacity as high as 5 mAh cm^(-2).Na–CO_(2) full cell with the Na/FG anode is able to sustain a stable cycling of 391 cycles at a limited capacity of 1000 mAh g^(-1).Long cycle life of the cell can be attributed to the protecting effect of the in situ fabricated NaF-rich SEI layer on metallic *** experiments and density functional theory(DFT)calculations confirm the formation of the NaF-rich SEI *** inhibition effect of the NaF-rich SEI layer for Na dendrites is verified by in situ optical microscopy observations.

关键词： composite anode fluorinated graphene Na dendrite Na-CO_(2)battery NaFrich protecting layer