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花生种质资源对黄曲霉菌侵染和产毒的抗性鉴定

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中国油料作物学报 2005年第3期27卷 21-25页

作者：姜慧芳任小平王圣玉中国农业科学院油料作物研究所农业部油料作物遗传改良重点实验室湖北武汉430062

对不同种子成分的花生种质资源对黄曲霉菌侵染和产毒的抗性进行了鉴定,结果表明,高含油量、高蛋白质含量和高油酸含量资源对黄曲霉菌侵染和产毒的抗性较差。通过对抗黄曲霉侵染和产毒能力不同的花生种质资源的种子成分的分析表明,高抗... 详细信息

对不同种子成分的花生种质资源对黄曲霉菌侵染和产毒的抗性进行了鉴定,结果表明,高含油量、高蛋白质含量和高油酸含量资源对黄曲霉菌侵染和产毒的抗性较差。通过对抗黄曲霉侵染和产毒能力不同的花生种质资源的种子成分的分析表明,高抗黄曲霉菌侵染和产毒资源的亚油酸含量较高。相关分析表明,不同花生品种对黄曲霉菌的侵染抗性与种子大小和油酸含量呈显著负相关,与出仁率和亚油酸含量呈显著正相关;不同花生品种对黄曲霉菌产毒的抗性与含油量呈显著负相关。通过鉴定和筛选,发掘出2份优质抗病资源。

关键词：花生种质资源种子品质性状黄曲霉菌侵染产毒

Preparation of Modified Composite Nanofiltration Membrane Synergistically Using Carboxylic Multi- walled Carbon Nanotube and β-cyclodextrin

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 232-239页

作者： LIU Peng MAO Junpeng FANG Yanfeng yu yunwu CHEN Changxiu TANG Ning WAN Ye GU Yaxin LIU yunxue wang Lihua School of Materials Science and Engineering Shenyang Jianzhu UniversityShenyang 110168China

A new modified blend ultrafiltration(UF)membrane with good hydrophilicity,high porosity and excellent anti-fouling performance was developed by using carboxylic multi-walled carbon nanotube(CMWCNT)as casting solution ***,a composite nanofiltration(NF)membrane with large water flux and good retention rate was fabricated by using the PVDF/CMWCNT blend UF membrane as the substrate,and polyvinyl alcohol(PVA),β-cyclodextrin(β-CD)and polyethylenimine(PEI)as the coating *** results show that with the appropriate addition of CMWCNT in the casting solution,the surface roughness,porosity and recovery rate of the PVDF/CMWCNT blend UF membrane is obviously *** water flux of blend UF membrane is significantly improved when the CMWCNT content increases from 0 wt%to 0.2 wt%.The water flux of blend UF membrane with 0.2 wt%CMWCNT is 162.7 L/(m^(2)·h),which is 44.3%higher than that of the pure PVDF ***β-CD content is 0.8 wt%,the retention rate of Congo red by PVDF/CMWCNT/β-CD composite NF membrane reaches 98.7%,which is 28.3%higher than that of single PVA/PEI modified *** research will provide a new idea and simple method for developing novel high-performance composite NF membranes.

关键词： CMWCNT cyclodextrin nanofiltration membrane

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自锁托槽临床效果评价的现状

海南医学 2010年第20期21卷 142-144页

作者：王生瑜袁小平泸州医学院口腔医学院附属口腔医院正畸科四川泸州646000

从自锁托槽问世以来,自锁托槽引起了人们的极大关注,有关自锁托槽与传统托槽的优缺点相关文章也特别多,众说纷纭。于是人们对自锁托槽的应用也是谨小慎微,有所顾忌。因此,本文就自锁托槽目前在临床中应用的确切效果进行总体评价,以期让... 详细信息

从自锁托槽问世以来,自锁托槽引起了人们的极大关注,有关自锁托槽与传统托槽的优缺点相关文章也特别多,众说纷纭。于是人们对自锁托槽的应用也是谨小慎微,有所顾忌。因此,本文就自锁托槽目前在临床中应用的确切效果进行总体评价,以期让人们对自锁托槽有总体认识,在临床中的应用起一定指导作用。

关键词：正畸托槽自锁托槽传统托槽

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建教师错题本堵数学学习漏洞

宁波教育学院学报 2015年第6期17卷 128-131页

作者：陈萍王盛裕宁波市实验学校浙江宁波315016 宁波市惠贞书院浙江宁波315010

在"学生错题本"的基础上,尝试了"教师错题本"。发现其是一种不但有利于学生有效订正,提高学生纠错能力,培养学生系统性学习能力,也能提高教师本人业务水平的方法。

关键词：数学教学数学学习教师错题本

哈尔滨市老年人膝关节骨性关节炎血清金属元素分析及生物标志物筛选

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黑龙江医学 2021年第1期45卷 84-87,90页

作者：王声雨崔宇林源哈尔滨医科大学附属第二医院黑龙江哈尔滨150000 哈尔滨医科大学卫生管理学院黑龙江哈尔滨150086

目的:探讨哈尔滨市老年人膝关节骨性关节炎患者血清中金属元素的分布情况,并进行生物标志物的筛选。方法:选取哈尔滨医科大学附属第二医院关节外科收治膝关节骨性关节炎患者76人和对照组患者71人作为研究对象;采集患者血清样本,用电感... 详细信息

目的:探讨哈尔滨市老年人膝关节骨性关节炎患者血清中金属元素的分布情况,并进行生物标志物的筛选。方法:选取哈尔滨医科大学附属第二医院关节外科收治膝关节骨性关节炎患者76人和对照组患者71人作为研究对象;采集患者血清样本,用电感耦合等离子体质谱(ICP-MS)测定血清中21种金属元素含量。并以寻找膝关节骨性关节炎早期诊断生物学标志物为目标,对检测结果进行一系列多变量统计分析。结果:膝关节骨性关节炎组与对照组相比,Li、Cr、Mn、Co、Cu、Se,6种元素的含量有显著差异(P<0.05),其中Cr、Mn、Se,3种元素在膝关节骨性关节炎患者血清中含量下降;Li、Co、Cu,3种元素在膝关节骨性关节炎患者血清中含量升高。利用PLS-DA筛选生物标志物,并应用变量重要性投影和载荷图对生物标志物进行确认。发现Li、Cr、Co、Mn四种元素可以认为是膝关节骨性关节炎早期诊断的生物标记物。结论:哈尔滨市膝关节骨性关节炎老年人血清金属元素含量发生异常,与膝关节骨性关节炎的发生、发展具有相关性。Li、Cr、Co、Mn可作为诊断膝关节骨性关节炎潜在的、有意义的生物学标志物。

关键词：骨性关节炎金属元素膝关节电感耦合等离子体质谱

Fabrication of carbon-supported Al2O3 nanoparticles via spontaneous cross-linking to enhance selective hydrogenation of furfural

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Journal of Energy Chemistry 2025年第1期100卷 612-620页

作者： Weiwei yu Xinbao Zhang Hongyu Chen Yanan wang Shaoguo Li Fucun Chen Zhenni Liu Xiujie Li Xiangxue Zhu State Key Laboratory of Catalysis Dalian Institute of Chemical Physics Chinese Academy of Sciences

Selective hydrogenation of furfural to furfuryl alcohol is a great challenge in the hydrogenation field due to thermodynamic preference for hydrogenation of C=C over C=***,a novel Al2O3/C-u hybrid catalyst,composed of N-modified dendritic carbon networks supporting Al2O3nanoparticles,was successfully prepared via carbonizing the freeze-dried gel from spontaneous cross-linking of alginate,Al3+and *** obtained carbon-supported Al2O3hybrid catalyst has a high ratio （31%） of Al species in pentahedral-coordinated *** introduction of urea enhances the surface N content,the ratio of pyrrolic N,and specific surface area of catalyst,leading to improved adsorption capacity of C=O and the accessibility of active *** the furfural hydrogenation reaction with isopropyl alcohol as hydrogen donor,Al2O3/C-u catalyst achieved a 90%conversion of furfural with 98.0% selectivity to furfuryl alcohol,outperforming that of commercial γ-***,Al2O3/C-u demonstrates excellent catalytic stability in the recycling tests attributed to the synergistic effect of abundant weak Lewis acid sites and the anchoring effect of the carbon network on *** work provides an innovative and facile strategy for fabrication of carbon-supported Al2O3hybrid catalysts with rich AlVspecies,serving as a high selective hydrogenation catalyst through MPV reaction route.

关键词： Selective hydrogenation Furfural Furfuryl alcohol Cross-linking Carbon supported Al 2 O 3 MPV route

Antithetical impacts of deleterious LRP1B mutations in non-squamous and squamous NSCLCs on predicting benefits from immune checkpoint inhibitor alone or with chemotherapy over chemotherapy alone: retrospective analyses of the POPLAR/OAK and CHOICE-01 trial

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Science China Life Sciences 2025年第1期 249-262页

作者： Jinliang wang Wenyong Zhou yu Xu Jianchun Duan Qiaoxia Zhou Guoqiang wang Leo Li Chunwei Xu Wenxian wang Shangli Cai Zhijie wang Jie wang Department of Oncology The Fifth Medical Center of Chinese PLA General Hospital Department of Thoracic Surgery Shanghai Chest HospitalSchool of MedicineShanghai Jiao Tong University Burning Rock Biotech CAMS Key Laboratory of Translational Research on Lung Cancer State Key Laboratory of Molecular OncologyDepartment of Medical OncologyNational Cancer Center/National Clinical Research Center for ancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical College Institute of Basic Medicine and Cancer (IBMC) Chinese Academy of Sciences Department of Clinical Trial The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

In non-small cell lung cancers,the non-squamous and squamous subtypes（nsqNSCLC and sqNSCLC） exhibit disparities in pathophysiology,tumor immunology,and potential genomic correlates affecting responses to immune checkpoint inhibitor（ICI）-based *** our inhouse training cohort（n=85）,the presence of the LRP1B deleterious mutation（LRP1B-del） was associated with longer and shorter progression-free survival（PFS） on ICIs alone in nsqNSCLCs and sqNSCLCs,respectively(Pinteraction=0.008).These results were validated using a larger public ICI cohort(n=208,Pinteraction<0.001).Multiplex immunofluorescence staining revealed an association between LRP1B-del and increased and decreased numbers of tumor-infiltrating CD8+T cells in nsqNSCLCs（P=0.040） and sqNSCLCs（P=0.014）,*** the POPLAR/OAK cohort,nsqNSCLCs with LRP1B-del demonstrated improved PFS benefits from atezolizumab over docetaxel(hazard ratio（HR）=0.70,P=0.046),whereas this benefit was negligible in those without LRP1B-del（HR=1.05,P=0.64）.Conversely,sqNSCLCs without LRP1B-del benefited more from atezolizumab（HR=0.60,P=0.002） than those with LRP1B-del（HR=1.30,P=0.31）.Consistent results were observed in the in-house CHOICE-01 cohort,in which nsqNSCLCs with LRP1B-del and sqNSCLCs without LRP1B-del benefited more from toripalimab plus chemotherapy than from chemotherapy alone(Pinteraction=0.008).This multi-cohort study delineates the antithetical impacts of LRP1B-del in nsqNSCLCs and sqNSCLCs on predicting the benefits from ICI alone or with chemotherapy over chemotherapy *** findings highlight the distinct clinical utility of LRP1B-del in guiding treatment choices for nsqNSCLCs and sqNSCLCs,emphasizing the necessity for a detailed analysis based on pathological subtypes when investigating biomarkers for cancer therapeutics.

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Direct Photolithography of WO_(x)Nanoparticles for High‑Resolution Non‑Emissive Displays

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Nano-Micro Letters 2025年第3期17卷 297-309页

作者： Chang Gu Guojian Yang Wenxuan wang Aiyan Shi Wenjuan Fang Lei Qian Xiaofei Hu Ting Zhang Chaoyu Xiang yu‑Mo Zhang Laboratory of Optoelectronic Information Technology and Devices Ningbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo 315201People’s Republic of China Hangzhou Bay Laboratory of Advanced Nano‑Optoelectronic Materials and Devices Qianwan Institute of CNITECHNingbo 315336People’s Republic of China Smart Materials for Architecture Research Lab Innovation Center of Yangtze River DeltaZhejiang UniversityJiaxing 314100People’s Republic of China University of Science and Technology of China Hefei 230026People’s Republic of China State Key Lab of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchun 130012People’s Republic of China

High-resolution non-emissive displays based on electrochromic tungsten oxides(WOx)are crucial for future near-eye virtual/augmented reality interactions,given their impressive attributes such as high environmental stability,ideal outdoor readability,and low energy ***,the limited intrinsic structure of inorganic materials has presented a significant challenge in achieving precise patterning/pixelation at the micron ***,we successfully developed the direct photolithography for WOx nanoparticles based on in situ photo-induced ligand *** strategy enabled us to achieve ultra-high resolution efficiently(line width3600 cycles),as well as promising applications in electronic logos,pixelated displays,flexible electronics,*** success and advancements presented here are expected to inspire and accelerate research and development(R&D)in high-resolution non-emissive displays and other ultra-fine micro-electronics.

关键词： Electrochromic Direct photolithography WOx nanoparticles In situ photo-induced ligand exchange High-resolution displays

可视喉镜联合光棒应用于咽喉部新生物患者的临床可行性分析

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复旦学报（医学版） 2020年第3期47卷 334-338页

作者：徐睿贾继娥乔晖王圣钰陈静陆艺复旦大学附属眼耳鼻喉科医院麻醉科上海200031

目的观察咽喉部新生物患者采用可视喉镜联合光棒行麻醉气管插管的临床价值。方法选择2018年12月至2019年3月于复旦大学附属眼耳鼻喉科医院择期行咽喉部新生物全麻手术的患者120例,采用随机数字表法分为可视喉镜组(A组,n=40)、帝视光棒... 详细信息

目的观察咽喉部新生物患者采用可视喉镜联合光棒行麻醉气管插管的临床价值。方法选择2018年12月至2019年3月于复旦大学附属眼耳鼻喉科医院择期行咽喉部新生物全麻手术的患者120例,采用随机数字表法分为可视喉镜组(A组,n=40)、帝视光棒组(B组,n=40)和可视喉镜联合帝视光棒组(C组,n=40)。观察并比较3组患者麻醉诱导前(T0)、诱导后即刻(T1)、气管插管后即刻(T2)和插管后3 min(T3)的血流动力学指标、首次气管插管成功率、总体插管成功率、插管时间,并同时记录插管期的相关并发症包括有无唇齿、牙龈出血、牙齿松动及口咽喉部出血情况。结果C组插管时间和首次插管成功例率与B组比较,差异均有统计学意义[(28.9±9.9)s vs.(38.5±12.4)s,40(100%)vs.33(82.5%),P均<0.05]。B组气管插管后即刻(T2)的平均动脉压低于A组[(79±6)mmHg vs.(101.5±13.3)mmHg],C组插管即刻的心率高于A组[(102.6±9.3)次/分vs.(94.2±12.7)次/分],差异均有统计学意义。T0、T1、T3时间点3组心率、平均动脉压差异均无统计学意义。A组患者中2例出现牙龈少量渗血、1例会厌新生物少量出血,并发症发生率为7.5%。B组患者无明显并发症。C组患者有1例出血牙龈少量渗血,并发症发生率为2.5%。结论联合使用可视喉镜和光棒,制定个性化的插管方案,可以发挥不同气道工具的优势,提高咽喉部新生物患者的插管成功率,缩短插管时间,减少并发症的发生。

关键词：可视喉镜光棒咽喉部新生物