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Kinetic modeling of high-temperature oxidation of pure Mg

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Journal of Magnesium and Alloys 2020年第3期8卷 819-831页

作者： Sa Ma Fangzhou Xing Na ta Lijun Zhang State Key Laboratory of Powder Metallurgy Central South UniversityChangshaHunan 410083P.R.China Max-Planck-Institut fiir Eisenforschung GmbH Max-Planck-Straβe 140237DusseldorfGermany

A variety of experimental tracer diffusivities of Mg and O in magnesium oxide available in the literature were first *** mobilities including bulk and short-circuit diffusion of Mg and O were then obtained by means of the CALPHAD(Calculation of Phase Diagram)***,the diffusion-controlled kinetic model of oxidation in a gas-MgO-Mg environment was developed based on the moving boundary model and Fick's law,coupling with the modified thermodynamic description of MgO.A mathematical expression for parabolic rate constant kp of the oxide scale was derived for magnesia and correlated with the thermodynamic and diffusion kinetic *** evaluated kp results were in line with the experimental ***,the oxidation process of pure magnesium at 673 K was model-predicted,and the predicted evolution of the oxide thicknesses agreed very well with the experimental *** was indicated that the grain boundaries diffusion of magnesium cations predominated the high temperature oxidation process.

关键词： MgO Diffusion Oxidation Atomic mobility CALPHAD Wagner's model

Peripheral T-Cell Lymphoma of Cervical Spine

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Surgical Science 2012年第2期3卷 96-99页

作者： Foot-Juh Lian Wen-Chiuan tsai Cheng-ta Hsieh Department of Pathology Tri-Service General Hospital National Defense Medical Center Taipei Taiwan (China) Division of Neurosurgery Department of Surgery Cathay General Hospital Taipei Taiwan (China)

Peripheral T-cell lymphoma is a rather uncommon non-Hodgkin’s lymphoma with the initial manifestation of spinal cord compression. Herein, we reported a 74-year-old woman with sustained neck pain radiating into the right shoulder and arm and weakness of the right upper extremity. A mass that had invaded the C5 and C6 vertebral bodies, causing a kyphotic curvature and compressing the spinal cord, was discovered with magnetic resonance imaging. The patient then underwent anterior corpectomy at C5 and C6, and reconstruction with a titanic rod and bone cement. The pathology confirmed a diagnosis of peripheral T-cell lymphoma after serial H & E and immunohistochemical staining. She recovered well from her profound neurological deficit. Both chemotherapy and radiotherapy were used postoperatively. Surgical intervention is indicated in these cases to decompress the cord, remove the majority of the tumor mass, stabilize the spine and obtain tissue for pathological diagnosis.

关键词： Spinal Cord Compression Vertebral Neoplasm Cervical Spine Peripheral T-Cell Lymphoma

经皮自控电刺激耳神门穴对乳腺癌术后疼痛及恶心、呕吐的影响

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同济大学学报（医学版） 2024年第1期45卷 100-105页

作者：李菁彭生翁浩锦州医科大学研究生培养基地(上海市奉贤区中心医院)麻醉科上海201400 上海中医药大学附属龙华医院麻醉科上海200030

目的观察经皮自控电刺激耳神门穴对乳腺癌术后疼痛及恶心、呕吐发生率的影响。方法选择2022年10月—2023年3月拟实施择期乳腺癌手术的患者80例。采用随机数字表分为耳神门穴刺激组(transcutaneous auricular Shenmen stimulation,ta-SMS... 详细信息

目的观察经皮自控电刺激耳神门穴对乳腺癌术后疼痛及恶心、呕吐发生率的影响。方法选择2022年10月—2023年3月拟实施择期乳腺癌手术的患者80例。采用随机数字表分为耳神门穴刺激组(transcutaneous auricular Shenmen stimulation,ta-SMS组)和对照组(C组),每组40例。ta-SMS组入手术室后在预麻间行耳神门穴电刺激30 min、进入麻醉恢复室后即刻及回到病房后每隔3 h自控行经皮耳神门穴电刺激30 min。C组除不予耳穴电刺激外,其余处理同ta-SMS组。记录两组患者入室时心率(heart rate,HR)、平均无创血压(mean blood pressure,MBP)、脑电双频指数(bispectral index,BIS)及术后24、48、72 h的恶心、呕吐(post-operative nausea and vomiting,PONV)发生率;比较两组患者术后视觉模拟评分法(visual analogue scale,VAS)疼痛评分变化、镇痛泵按压总次数以及手术前后血清5-羟色胺(5-HT)表达水平。结果ta-SMS组患者较C组术后72 h内恶心、呕吐发生率显著降低(P0.05);ta-SMS组PCIA按压总次数、镇痛复合液总消耗量降低,差异有统计学意义(P0.05);ta-SMS组术后24、48、72 h血清5-HT水平显著低于C组,差异有统计学意义(P<0.05)。结论多次经皮自控电刺激耳神门穴可降低乳腺癌手术后72 h内恶心、呕吐的发生率,缓解患者疼痛;5-HT的表达下调参与了其过程。

关键词：耳神门穴经皮穴位电刺激乳腺癌术后恶心呕吐 5-羟色胺

Functional,chemical,and sensorial properties of gluten-free fermented instant soup powders developed by use of mung bean and drum drying process

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Food Bioscience 2022年第3期47卷 1070-1081页

作者： Bilge taşkın NazlıSavlak Department of Food Engineering Faculty of EngineeringManisa Celal Bayar University45140YunusemreManisaTurkey

There is a potent demand to develop novel gluten-free food alternatives that are nutritious and ***-free instant fermented soup powder was developed by partial substitution of rice flour with mung bean *** of drum drying conditions;feed moisture(45–65%),drum rotating speed(0.6–2.2 rpm),and steam pressure(75–95 psi)on functional,chemical,sensorial,and morphological properties of soup powders were *** powders exhibited high protein content(20.52–22.62%)and remarkable amounts of dietary fibers(2.63–3.94%),total phenolics(2.23–3.64μg GAE/g),and antioxidant capacities(DPPH:6.28–9.96μmol TEAC/g,FRAP:26.02–42.88μmol/g).The instant structure of the soup powder was provided by water solubility(17.93–23.14%),water absorption(3.20–4.20 g/g),and gelatinization degree(82.92–97.60%)analyses,as well as SEM appearances and DSC *** conditions were determined as 57.55%feed moisture,1.00 rpm rotating speed,and 91.27 psi steam *** instant soup powders had enhanced chemical,functional and bioactive properties,and can be used practically in daily and social life by celiac patients or gluten sensitive *** bean was proven to be a valid option for novel application opportunities in gluten-free systems.

关键词： Gluten-free Antioxidant activity Mung bean Optimization Instant soup Drum drying Quality characteristics

Study on the dynamic behavior of herringbone gear structure of marine propulsion system powered by double-cylinder turbines

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Science China(Technological Sciences) 2022年第3期65卷 611-630页

作者： XU JiangHai JIAO ChunXiao ZOU DongLin ta Na RAO ZhuShi State Key Laboratory of Mechanical System and Vibration Institute of VibrationShock and NoiseShanghai Jiao Tong UniversityShanghai 200240China Collaborative Innovation Center for Advanced Ship and Deep-Sea Exploration Shanghai 200240China

Propulsion systems powered by double-cylinder turbines(DCT)are widely used in large-scale ***,the nonlinear instability leads to hidden dangers associated with the safe operation,and there is a lack of theoretical and systematic research on this *** on the gear transmission principle and non-Newtonian thermal elastohydrodynamic lubrication(EHL)theory,a torsional model of a two-stage herringbone system forced by unsymmetrical load is *** nonlinear and time-varying factors of meshing friction,meshing stiffness,and gear pair backlash are included in the model,and multiple meshing states,including single-and double-sided impact are *** nonlinear phenomena of the dynamic system are explored and the effects of the unsymmetrical load on the system stability are *** results indicate that the stability of the gear system is improved,and that the back-sided impact gradually disappears with the increases of load ratio between the two inputs and the input load ***,it is found that the gear pairs on the low-load side experience more severe vibration than those on the high-load ***,the stability of the gear pairs decreases along the power transmission path of the multistage gear *** results of this research will be useful when making predictions of the stability of such systems and in the optimization of the load parameters.

关键词： DCT propulsion system DI-SO herringbone gears unsymmetrical load nonlinear instability mechanism

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可编织、可穿戴的宽带聚合物超声换能器

Science China Materials 2024年第8期67卷 2653-2660页

作者：邹君逸郭星奕吴家琦徐冬梅许凯亮陈培宁他得安彭慧胜 State Key Laboratory of Molecular Engineering of Polymers Department of Macromolecular Science Institute of Fiber Materials and DevicesLaboratory of Advanced MaterialsFudan UniversityShanghai 200438China Department of Biomedical Engineering Yiwu Research Institute and Shanghai Poda Medical Technology Co.Ltd.Fudan UniversityShanghai 200438China

新兴的物联网技术推动了可穿戴健康监测设备的快速发展.目前,医学超声技术在严重慢性疾病的长时间监测方面具有广阔的应用前景.然而,商用超声探头一般都是刚性的,需要手持,难以满足医疗可穿戴设备对柔性化、小型化和舒适性的要求.本文... 详细信息

新兴的物联网技术推动了可穿戴健康监测设备的快速发展.目前,医学超声技术在严重慢性疾病的长时间监测方面具有广阔的应用前景.然而,商用超声探头一般都是刚性的,需要手持,难以满足医疗可穿戴设备对柔性化、小型化和舒适性的要求.本文提出了一种可编织、可穿戴的聚合物超声换能器,该换能器由匹配层、背衬层和压电层组成.聚合物压电材料的带宽(93%)是压电陶瓷的7倍,并且可以承受超过10,000次的弯曲和扭曲变形.该传感器能监测颈动脉血液流速,心脏血液流速和心脏血管的血管厚度,并具有与商用探头相当的信噪比.它的宽带特性(3.68–10.08 MHz)使其能通过调整频率来监测不同的组织.可编织超声换能器可以制成纤维形式,并编织成透气织物,在不牺牲穿戴舒适性的情况下进行实时血管监测.

关键词：血液流速超声换能器可穿戴设备超声探头扭曲变形匹配层慢性疾病压电材料

CCT各亚基在甲状腺癌中的表达及其对患者临床预后、肿瘤微环境和化疗药物敏感性的影响

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中国肿瘤生物治疗杂志 2024年第9期31卷 895-906页

作者：施晓辉白云峰塔拉白银宝顾佳慧内蒙古自治区人民医院肿瘤中心甲状腺肿瘤外科内蒙古呼和浩特010000 内蒙古科技大学包头医学院研究生院内蒙古包头014000

目的:探究含t-复合物1的伴侣蛋白(CCT)的8个亚基在甲状腺癌(TC)组织中的表达及其与TC分期、患者预后、免疫细胞浸润、免疫检查点表达和化疗药物敏感性的相关性。方法:采用TCGA数据库数据分析CCT各亚基在TC组织和癌旁组织中的表达;用TCG... 详细信息

目的:探究含t-复合物1的伴侣蛋白(CCT)的8个亚基在甲状腺癌(TC)组织中的表达及其与TC分期、患者预后、免疫细胞浸润、免疫检查点表达和化疗药物敏感性的相关性。方法:采用TCGA数据库数据分析CCT各亚基在TC组织和癌旁组织中的表达;用TCGA数据库数据分析CCT各亚基表达与TC患者预后的关系;用GSEA法分析CCT各亚基的生物学功能;用TCGA和TIMER2.0数据库数据分析CCT各亚基表达与肿瘤微环境、免疫细胞浸润、化疗药物敏感性、免疫检查点表达的相关性。结果:数据库数据分析显示,在TC组织中CCT3、CCT7和CCT8 mRNA均呈高表达(P<0.01或P<0.001),而CCT1、CCT2、CCT5和CCT6B mRNA均呈低表达(P<0.01或P<0.001);CCT3、CCT6B、CCT8 mRNA的表达与T分期有关联(P<0.05或P<0.01)、CCT6B mRNA的表达与淋巴结转移有关联(P<0.01),CCT5 mRNA的表达与远处转移有关联(P<0.05),CCT6B可能是TC患者OS的独立预后生物标志物;CCT各亚基mRNA表达主要富集于移植物排斥、补体和干扰素-γ等信号通路;CCT各亚基mRNA低表达组TC组织的基质、免疫和综合评分均显著高于高表达组(P<0.05或P<0.01或P<0.001);CCT各亚基mRNA表达与TC的基质评分、免疫评分和综合评分均呈负相关(均P<0.01);CCT各亚基mRNA的表达与CD8+T细胞和巨噬细胞浸润均呈正相关(均P<0.05),多数CCT亚基(CCT6B和CCT7除外)的mRNA表达与中性粒细胞的浸润呈正相关(P<0.05或P<0.01或P<0.001),而CCT3、4、7、8mRNA的表达与CD4+T细胞浸润呈负相关(均P<0.05);与低表达组比较,大多数CCT亚基mRNA高表达的TC患者对索拉非尼、乐伐替尼、达拉非尼、曲美替尼、凡德他尼和卡博替尼等化疗药物的IC50均明显升高(P<0.05或P<0.01或P<0.001);TC组织中CCT各亚基mRNA的表达与PD-1、PD-L1、PD-L2、CTLA4、CD80和CD86表达均有明显关联(P<0.05或P<0.01或P<0.001)。结论:CCT复合物可能通过影响肿瘤微环境促进TC的发生发展,进而影响患者预后,其可成为难治性TC诊断和免疫治疗的潜在靶点。

关键词：甲状腺癌 CCT复合物预后免疫细胞浸润药物敏感性

近40 a昆仑山北麓典型河流生态基流时空特征

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长江科学院院报 2024年第1期41卷 44-51页

作者：胡可可何建村赵健塔依尔苏里坦中国科学院新疆生态与地理研究所荒漠与绿洲生态国家重点实验室乌鲁木齐830011 中国科学院大学资源与环境学院北京100049 新疆维吾尔自治区水利厅水资源规划研究所乌鲁木齐830000

生态基流是河流生态系统健康稳定的关键,对于水资源缺乏的干旱区内陆河流尤为重要。以昆仑山北麓克里雅河、尼雅河与车尔臣河3条典型季节性内陆河为研究对象,选取1978—2014年流域水文数据,利用QP法、Tennant法、近10 a最枯月平均流量法... 详细信息

生态基流是河流生态系统健康稳定的关键,对于水资源缺乏的干旱区内陆河流尤为重要。以昆仑山北麓克里雅河、尼雅河与车尔臣河3条典型季节性内陆河为研究对象,选取1978—2014年流域水文数据,利用QP法、Tennant法、近10 a最枯月平均流量法和Texas法4种水文学方法,计算确定河流生态基流并据此分析其时空分异特征与影响因素。结果表明:Tennant法更适合昆仑山北麓河流生态基流计算。从时间变化来看,3条河生态基流年内最大值均出现在7月份,最小值均出现在1月份;年生态基流最大值均出现在2010年左右,最小值在1980年前后,分别以1.378、0.653、3.066 m^(3)/s·(10 a)^(-1)的速度增加。3条河流生态基流空间分布,春季表现为车尔臣河>克里雅河>尼雅河,夏季和秋季均表现为克里雅河>车尔臣河>尼雅河,且同一河流波动变化明显,不同河流之间变化差异不显著(p>0.05)。影响生态基流年内时空差异的主要因素分别是气温、降水和人类活动,其中以车尔臣河流域气温、降水与生态基流的相关性最强,相关系数r分别为0.876、0.917。考虑生态基流时空分布与流域气候变化特征,综合提出3条河流年内各月生态基流管控目标。研究结果可为昆仑山北麓河流生态保护与水资源管理调度提供参考。

关键词：生态基流时空特征 Tennant法管控目标昆仑山北麓

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Simulation of thermoacoustic waves by a pressure-based algorithm for compressible flows

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Acta Mechanica Sinica 2012年第3期28卷 819-824页

作者： Wei Li Qi-sheng Chen Key laboratory of Microgravity Institute of MechanicsChinese Academy of Sciences15 Beisihuan West Road100190 BeijingChina

A modified SIMPLEC method which can solve compressible flows at low Mach number is introduced and used to study thermoacoustic waves induced by a rapid change of temperature at a solid wall and alternating- direction flows generated by thermoacoustic effects in a ta- pered resonator. The results indicate that the algorithm adopted in this paper can be used for calculating com- pressible flows and thermoacoustic waves. It is found that the pressure and velocity in the resonator behave as stand- ing waves, and the tapered resonator can suppress high- frequency harmonic waves as observed in a cylindrical res- onator.

关键词： Compressible flow Thermoacoustic wave Resonator. SIMPLEC