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Science China Earth Sciences 2021年第7期64卷 1195-1206页

作者： Zigen WEI Risheng CHU Zhiwei li Minhan sheng qiu ZENG Slate Key Laboratory of Geodesy and Earth's Dynamics Innovation Academy for Precision Measurement Science and TechnologyChinese Academy of SciencesWuhan 430077China Science and Technology on Reliability and Environmental Engineering Laboratory Beijing Institute of Spacecraft Environment EngineeringBeijing 100094China

Landslides are recurrent geological phenomena on Earth that cause heavy casualties and property losses *** this study,we use the V_(p)-k stacking and nonlinear waveform inversion methods of high-frequency receiver functions extracted from local earthquakes,to sequentially invert Poisson’s ratios and S-wave velocities of the Quaternary Xishancun landslide,which is composed of three segments,i.e.,h1,h2,and h3 from bottom to *** results show that Poisson’s ratio values are generally higher than 0.33 and that the S-wave velocities vary from 0.1 to 0.9 km s^(-1).High Poisson’s ratios(>0.44)are mainly distributed in the juncture regions between different segments,as well as the western edge of *** zones show significant variation in landslide thickness and are potentially hazardous *** velocities of 0.05–0.2 km s^(-1)with thicknesses of 10–30m are widely observed in the lower layer of the *** high Poisson’s ratios and low-velocity layer may be related to water-rich materials in these *** study suggests that the high-frequency receiver functions from local earthquakes can be used to delineate geotechnical structures,which is valuable for landslide stability analysis and hazard mitigation.

关键词： Xishancun landslide High-frequency receiver functions High Poisson's ratio Low S-wave velocity Landslide stability and hazard mitigation

乳清蛋白-果胶高内相乳液凝胶对低脂再制奶酪的品质影响

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食品科学 2025年第2期46卷 57-64页

作者：李红娟李振任钏袁玉京李可邱晓豹李洪波于景华天津科技大学食品科学与工程学院食品营养与安全国家重点实验室天津300457

以乳清蛋白和果胶、葡聚糖为主要原料,采用酸诱导法制备乳清蛋白-果胶乳液凝胶(whey protein-pectin emulsion gel,WP)和乳清蛋白-葡聚糖乳液凝胶(whey protein-glucan emulsion gel,WG),比较35%、75%分散相体积分数凝胶(分别记为WP35、... 详细信息

以乳清蛋白和果胶、葡聚糖为主要原料,采用酸诱导法制备乳清蛋白-果胶乳液凝胶(whey protein-pectin emulsion gel,WP)和乳清蛋白-葡聚糖乳液凝胶(whey protein-glucan emulsion gel,WG),比较35%、75%分散相体积分数凝胶(分别记为WP35、WG35、WP75、WG75)的功能特性,并进一步探究高内相乳液凝胶作为脂肪替代物在低脂再制奶酪中的代脂效果。结果表明:WP75的平均粒径最小,脂肪分布均匀,蛋白质网络结构稳定。乳液凝胶样品在0.1~10 Hz内弹性模量(G′)和黏性模量(G″)都随油相体积分数的升高呈上升趋势,其中WP75抵抗形变能力、热稳定性及持水性都优于其他样品。样品15%-WP75(添加WP75,脂肪质量分数15%的再制奶酪)油析性减弱,熔化性增强,质构特性与全脂对照无明显差异。研究表明乳清蛋白与果胶制备的高内相乳液凝胶在低脂奶酪产品有较好的脂肪替代效果,在低脂乳制品加工中具有良好的应用潜力。

关键词：乳清蛋白果胶葡聚糖高内相乳液凝胶低脂再制奶酪

腹腔镜辅助下腰大池-腹腔分流术治疗交通性脑积水的临床分析

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系统医学 2016年第12期1卷 58-60页

作者：韩斌邱胜利刘涛曹广辉吴坤赵庭生合肥市第二人民医院神经外科安徽合肥230011

目的探讨腹腔镜辅助下腰大池-腹腔分流术治疗交通性脑积水的临床效果。方法选取该院2013年1月—2015年4月收治的72例交通性脑积水患者为研究对象,采用随机数表法将患者分为观察组与对照组,每组36例。观察组行腹腔镜辅助下腰大池-腹腔分... 详细信息

目的探讨腹腔镜辅助下腰大池-腹腔分流术治疗交通性脑积水的临床效果。方法选取该院2013年1月—2015年4月收治的72例交通性脑积水患者为研究对象,采用随机数表法将患者分为观察组与对照组,每组36例。观察组行腹腔镜辅助下腰大池-腹腔分流术,对照组行常规腰大池-腹腔分流术。比较两组治疗效果及手术并发症发生情况。结果术后1周,两组GCS评分均较术前显著提高,但组间比较差异无统计学意义(P>0.05),术后6个月,观察组收缩期脑脊液峰流速为(4.13±1.76)cm/s,显著高于对照组(P0.05)。结论腹腔镜辅助下腰大池-腹腔分流术治疗交通性脑积水效果显著,且术后并发症较少,远期随访效果确切,值得在临床推广。

关键词：腹腔镜腰大池-腹腔分流术交通性脑积水

Kolmogorov's ε-Entropy of Bounded Sets in Discrete Spaces and Attractors of Dissipative Lattice Systems

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Acta Mathematica Sinica,English Series 2007年第2期23卷 313-320页

作者： sheng Fan ZHOU qiu li JIA Wei SHI Department of Applied Mathematics Shanghai Normal University Department of Mathematics and Physics He'nan University of Science and Technology Department of Mathematics Shanghai University

We obtain an estimate of the upper bound for Kolmogorov＇s ε-entropy for the bounded sets with small ＂tail＂ in discrete spaces, then we present a sufficient condition for the existence of a global attractor for dissipative lattice systems in a reflexive Banach discrete space and establish an upper bound of Kolmogorov＇s ε-entropy of the global attractor for lattice systems.

关键词： Kolmogorov's ε-entropy discrete space dissipative lattice system global attractor

Parallel decline of CD8+CD38+ lymphocytes and viremia in treated hepatitis B patients

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World Journal of Gastroenterology 2011年第17期17卷 2191-2198页

作者： Wei Cao Zhi-Feng qiu Tai-sheng li Department of Infectious Diseases Peking Union Medical College Hospital Peking Union Medical College Chinese Academy of Medical Sciences Beijing 100730 China

AIM:To assess the peripheral T lymphocyte subsets in chronic hepatitis B virus(HBV) infection,and their dynamics in response to adefovir dipivoxil ***:Proportions and absolute counts of peripheral natural killer cells,B cells,CD8+,CD4+,CD8+ CD38+,CD8+CD28+ and CD4+CD28+ T cells were determined using three-color flow cytometry in chronic hepatitis B patients(n = 35),HBV carriers(n = 25) and healthy controls(n = 35).Adefovir dipivoxil was initiated in 17 chronic hepatitis B patients who were regularly followed for 72 wk,during which period the T cell subsets and serum viral load were measured at each follow-up ***:The peripheral CD4+ T cell counts and CD8+ T cell counts decreased in chronic HBV *** chronic hepatitis B patients,proportions of CD8+CD38+ T cells were 62.0% ± 14.7%,much higher than those of HBV carriers and healthy *** the 13 hepatitis B patients who were treated and responded to adefovir dipivoxil,proportions of CD8+CD38+ T cells decreased from 53.9% ± 18.4% pre-therapy to 20.1% ± 11.3% by week 72(P line(HBV DNA fell from 7.31 to 3 log copies/mL).CD8+ T cell counts also underwent an average increase of 218 cells/μL by the end of 72-wk *** those who failed the therapy,the CD8+CD38+ T cell population had more ***:CD8+ T cells abnormally activated in chronic HBV infection can be partially reversed by antiviral ***-associated immune activation may be a crucial part of the pathogenesis and a promising target of treatment.

关键词： Hepatitis B virus Chronic hepatitis B CD8+CD38+ T cell subsets

A random walk with a branching system in random environments

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Science China Mathematics 2007年第5期50卷 698-704页

作者： Ying-qiu li Xu li Quan-sheng liU School of Mathematics and Computing Sciences Changsha University of Science and TechnologyChangsha 410076China LMAM University of Bretgne-SudBP57356017 VannesPrance

We consider a branching random walk in random environments, where the particles are reproduced as a branching process with a random environment (in time), and move independently as a random walk on ? with a random environment (in locations). We obtain the asymptotic properties on the position of the rightmost particle at time n, revealing a phase transition phenomenon of the system.

关键词： random walks in random environments branching processes in random environments rightmost particles phase transition large deviation 60J10 60F05

BIAS ERRORS INDUCED BY CONCENTRATION GRADIENT IN SEDIMENT-LADEN FLOW MEASUREMENT WITH PTV

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Journal of Hydrodynamics 2012年第5期24卷 668-674页

作者： li Dan-xun liN qiu-sheng ZHONG Qiang WANG Xing-kui State Key Laboratory of Hydroscience and Engineering Tsinghua UniversityBeijing 100084China

Sediment-laden flow measurement with Particle Tracking Velocimetry （PTV） introduces a series of finite-sized sampling bins along the vertical of the flow. Instantaneous velocities are collected at each bin and a significantly large sample is established to evaluate mean and root mean square （rms） velocities of the flow. Due to the presence of concentration gradient, the established sample for the solid phase involves more data from the lower part of the sampling bin than from the upper part. The concentration effect causes bias errors in the measured mean and rms velocities when velocity varies across the bin. These bias errors are analyti- cally quantified in this study based on simplified linear velocity and concentration distributions. Typical bulk flow characteristics from sediment-laden flow measurements are used to demonstrate rough estimation of the error magnitude. Results indicate that the mean velocity is underestimated while the rms velocity is overestimated in the ensemble-averaged measurement. The extent of devia- tion is commensurate with the bin size and the rate of concentration gradient. Procedures are proposed to assist determining an appro- priate sampling bin size in certain error limits.

关键词： bias error velocity concentration gradient

Treatment of chronic proliferative cholangitis with c-myc shRNA

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World Journal of Gastroenterology 2009年第1期15卷 95-101页

作者： Fu-Yu li Nan-sheng Cheng Jing-qiu Cheng Hui Mao li-sheng Jiang Ning li sheng He Department of Hepatobiliary Surgery West China Hospital of Sichuan University Chengdu 610041 Sichuan Province China Key Laboratory of Transplantation Engineering and Immunology West China Hospital of Sichuan University Chengdu 610041 Sichuan Province China

AIM： To investigate the feasibility and effectiveness of c-myc shRNA in inhibiting the hyperplastic behavior and lithogenic potentiality of chronic proliferative cholangitis （CPC）, in order to prevent stone recurrence and biliary restenosis. METHODS： An animal model of CPC was established by giving intralumenally 0.5 mL of c-myc shRNA. Then, the effects of c-myc shRNA on hyperplastic behavior and lithogenic potentiality of CPC were evaluated by histological observation, immunohistochemistry, real- time PCR and Western blotting for c-myc, proliferating cell nuclear antigen （PCNA）, procollagen m, mucin 5AC, enzymatic histochemistry for 13-glucuronidase, and biochemistry for hydroxyproline in the diseased bile duct. RESULTS： Treatment with c-myc shRNA efficiently suppressed the hyperplasia of biliary epithelium, submucosal gland, and collagen fiber by inhibiting mRNA and protein expression of c-myc. More importantly, it decreased the lithogenic potentiality of CPC by inhibiting the expression of mucin 5AC and the secretion of endogenous 13-glucuronidase. Further investigation indicated that c-myc shRNA-3 had a better inhibitory effect on CPC. CONCLUSION： Treatment with c-myc shRNA-3 can control CPC and reduce the lithogenic potentiality of CPC.

关键词： Chronic proliferative cholangitis Hepatoli-thiasis Recurrence C-myc Prevention

抗吡虫啉褐飞虱种群对天敌黑肩绿盲蝽抗性发展的影响

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西南农业学报 2017年第6期30卷 1369-1375页

作者：凌炎黄芊蒋显斌尹文兵龙丽萍黄凤宽黄所生吴碧球李成广西农业科学院植物保护研究所/广西作物病虫害生物学重点实验室广西南宁530007 广西农业科学院水稻研究所广西南宁530007 广东新景象生物工程有限公司广东广州510635

【目的】了解褐飞虱对吡虫啉产生极高水平抗性后对其主要捕食性天敌黑肩绿盲蝽抗性发展的影响,为协调化学防治与生物防治的关系提供科学依据。【方法】分别用对吡虫啉敏感的褐飞虱种群(SN种群)和极高抗种群(RN种群)连续饲养黑肩绿盲蝽2... 详细信息

【目的】了解褐飞虱对吡虫啉产生极高水平抗性后对其主要捕食性天敌黑肩绿盲蝽抗性发展的影响,为协调化学防治与生物防治的关系提供科学依据。【方法】分别用对吡虫啉敏感的褐飞虱种群(SN种群)和极高抗种群(RN种群)连续饲养黑肩绿盲蝽25代以及用吡虫啉对黑肩绿盲蝽连续诱导25代,每隔5代分别测定黑肩绿盲蝽的敏感性和酶活性。【结果】SNCF_(25)种群的敏感性变化不大;RNCF_(25)种群的LC_(50)值是原来的1.53倍;诱导(INCF_(25))种群LC_(50)值是原来的1.66倍。SNC、RNC和INC的黑肩绿盲蝽种群F_5、F_(10)、F_(15)、F_(20)、F_(25)代的酯酶和谷胱甘肽转移酶活性变化与抗性倍数的变化不一致,而多功能氧化酶活性变化与抗性倍数的变化较一致。【结论】黑肩绿盲蝽对吡虫啉的抗性发展较慢,其抗性发展与酯酶和谷胱甘肽转移酶的活性变化无关,与多功能氧化酶活性的变化成正相关。

关键词：吡虫啉褐飞虱黑肩绿盲蝽抗性发展

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World Journal of Clinical Cases 2025年第6期13卷 24-29页

作者： Wen-Jin Yuan Yi-Juan Zheng Bing-Rong Zhang Yi-Jie lin You li Yan-Yan qiu Xue-Ping Yu Department of Infection Disease Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian provinceFujian Medical University Affiliated First Quanzhou HospitalQuanzhou 362000Fujian ProvinceChina

BACKGROUND Hydroxyurea,an antimetabolite,is frequently prescribed for various hemato-logical disorders,and its common side effects include gastrointestinal problems,cutaneous or mucosal lesions and pyrexia/*** SUMMARY This study reports the case of a 67-year-old woman who developed recurrent abdominal pain after 10 years of continuous hydroxyurea therapy for primary *** revealed an ileocecal *** discontinuing hydroxyurea therapy for 6 months,follow-up colonoscopy showed a significant reduction in the *** We consider cecal ulcers as a rare complication of hydroxyurea therapy which typically resolves upon stopping the drug.

关键词： Hydroxyurea Ulcer Abdominal pain Thrombocythemia Colonoscopy Case report