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Chinese Chemical Letters 2024年第3期35卷 523-527页

作者： Pengfei Tan Chuanhui Zhu Jinjin Yang Shuang zhao Tao Xia mei-Huan zhao Tao Han Zheng Deng Man-Rong Li Key Laboratory of Bioinorganic and Synthetic Chemistry of Ministry of Education School of ChemistrySun Yat-sen UniversityGuangzhou 510006China School of Science and Engineering The Chinese University of Hong KongShenzhen 518172China Institute of Physics Chinese Academy of SciencesBeijing 100190China School of Science Hainan UniversityHaikou 570228China

The intricate correlation between multiple degrees of freedom and physical properties is a fascinating area in solid state chemistry and condensed matter ***,we report a quantum-magnetic system BaNi_(2)V_(2)O_(8)(BNVO),in which the spin correlation was modulated by unusual oxidation state,leading to different magnetic *** BNVO was modified with topochemical reduction(TR)to yield TR-BNVO with partially reduced valance state of Ni^(+)in the two-dimensional NiO_(6)-honeycomb ***,the antiferromagnetic order is suppressed by the introduction of locally interposed Ni^(+)and oxygen vacancies,resulting in a ferromagnetic ground state with the transition temperature up to 710 K.A positive magnetoresistance(7.5%)was observed in the TR-BNVO at 40 K under 7 *** findings show that topological reduction is a powerful approach to engineer low-dimensional materials and accelerate the discovery of new quantum magnetism.

关键词： Layered honeycomb oxide Topochemical reduction Oxygen vacancies Ferromagnetism Magnetoresistance

Lactobacillus plantarum CCFM1180 attenuates obesity induced by estrogen deficiency by activating estrogen receptor alpha in abdominal adipose tissue and regulating gut microbiota-derived metabolites

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Food Science and Human Wellness 2024年第2期13卷 765-777页

作者： Qian Chen Chunxia mei Min Guo Botao Wang Haiqin Chen Jianxin zhao Gang Wang Wei Chen State Key Laboratory of Food Science and Resources Jiangnan UniversityWuxi 214122China School of Food Science and Technology Jiangnan UniversityWuxi 214122China National Engineering Research Center for Functional Food Jiangnan UniversityWuxi 214122China (Yangzhou)Institute of Food Biotechnology Jiangnan UniversityYangzhou 225004China Bloomage Biotechnology Co. Ltd.Jinan 250000China

Lipid metabolism disorders commonly occur during *** deficiency has been shown to lead to excessive energy intake and abnormal lipid metabolism in ovariectomized rats,resulting in *** exhibit anti-obesity properties,and their underlying mechanism has been widely *** this study,we demonstrated the metabolic benefits of Lactobacillus plantarum CCFM1180 in suppressing appetite,controlling body weight,correcting obesity-induced abnormalities,enhancing liver lipid metabolism,and protecting liver function in estrogen-deficient *** mechanisms associated with the anti-obesity and anti-dyslipidemia effects of CCFM1180 on estrogen-deficient rats were *** results showed that CCFM1180 dramatically reduced food intake by activating the expression of estrogen receptor alpha(ERα)and increasing the level of leptin in abdominal adipose *** changes,combined with the increased butyrate concentration and recovered bile acid structure,helped enhance lipid ***,CCFM1180 treatment was found to be safer than exogenous estrogen ***,*** CCFM1180 could be considered a new therapeutic strategy for preventing and alleviating menopausal lipid abnormalities.

关键词： Bile acid Gut microbiota Menopause Ovariectomy Short chain fatty acid

Application value of dexmedetomidine in anesthesia for elderly patients undergoing radical colon cancer surgery

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2671-2678页

作者： Hui-Min Bu Min zhao Hong-mei Ma Xiao-Peng Tian Department of Anesthetic Surgery Qingdao Haici Hospital Affiliated to Qingdao University(Qingdao Hospital of Traditional Chinese Medicine)Qingdao 266033Shandong ProvinceChina

BACKGROUND Colon cancer presents a substantial risk to the well-being of elderly people *** advancements in medical technology,surgical treatment has become the primary approach for managing colon cancer ***,due to age-related physiological changes,especially a decline in cognitive function,older patients are more susceptible to the effects of surgery and anesthesia,increasing the relative risk of postoperative cognitive dysfunction(POCD).There-fore,in the surgical treatment of elderly patients with colon cancer,it is of pa-ramount importance to select an appropriate anesthetic approach to reduce the occurrence of POCD,protect brain function,and improve surgical success *** One hundred and seventeen patients with colon cancer who underwent elective surgery under general anesthesia were selected and divided into two groups:A and *** A received Dex before anesthesia induction,and B group received an equivalent amount of normal *** in the mini-mental state exami-nation,regional cerebral oxygen saturation(rSO2),bispectral index,glucose uptake rate(GluER),lactate production rate(LacPR),serum S100βand neuron-specific enolase(NSE),POCD,and adverse anesthesia reactions were compared between the two *** Surgical duration,duration of anesthesia,and intraoperative blood loss were comparable between the two groups(P>0.05).The overall dosage of anesthetic drugs used in group A,including propofol and remifentanil,was significantly lower than that used in group B(P<0.05).Group A exhibited higher rSO2 values at the time of endotracheal intubation,30 min after the start of surgery,and immediately after extubation,higher GluER values and lower LacPR values at the time of endotra-cheal intubation,30 min after the start of surgery,immediately after extubation,and 5 min after extubation(P<0.05).Group A exhibited lower levels of serum S100βand NSE 24 h postoperatively and a lower incidence of cognitive dysfunction on the 1st and

关键词： Colon cancer Dexmedetomidine General anesthesia Elderly Radical colon cancer surgery Bispectral index Cognitive function Regional cerebral oxygen saturation

Degradation of warm permafrost and talik formation on the Qinghai-Tibet Plateau in 2006-2021

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Advances in Climate Change Research 2024年第2期15卷 275-284页

作者： Qi-Hang mei Ji CHEN You-Qian LIU Shou-Hong ZHANG Jing-Yi zhao Tian-Chun DONG Jun-Cheng WANG Yao-Jun zhao Beiluhe Observation and Research Station of Frozen Soil Engineering and Environment Key Laboratory of Cryospheric Science and Frozen Soil EngineeringNorthwest Institute of Eco-Environmental and ResourcesChinese Academy of SciencesLanzhou 730000China China Railway Qinghai-Tibet Group Co.Ltd Xining 810007China University of Chinese Academy of Sciences Beijing 100049China

Permafrost is degrading globally,particularly those with low thermal stability on the Qinghai-Tibet Plateau,owing to climate ***,the inadequacy of direct research on permafrost degradation based on in-situ monitoring limits the prediction of permafrost degradation and engineering *** study explored the processes and modes of permafrost degradation into talik by analyzing ground temperature data from five points in the hinterland of the Qinghai-Tibet Plateau from 2006 to *** results showed that the degradation of the warm permafrost layer with a geothermal gradient of zero occurred simultaneously in the top and bottom *** rate of permafrost degradation from the top down and bottom up increase during the degradation process,but the increase of the former is more drastic after the formation of thawed ***,the construction of the Qinghai-Tibet Railway changed the degradation modes of the permafrost in adjacent natural sites through horizontal heat transfer,particularly after through talik formation under the *** findings suggest that taking countermeasures before or immediately after forming thawed interlayer is more *** evaluating the thermal impact of projects in warm permafrost regions,special attention should be given to the horizontal heat transfer process that may result from the formation of a through talik.

关键词： Warm permafrost Degradation Talik Qinghai-Tibet Plateau Climate change

Method for detector description conversion from DD4hep to Filmbox

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NUCLEAR SCIENCE AND TECHNIQUES 2024年第9期35卷 1-12页

作者： Yuan, zhao-Yang Song, Tian-Zi Zeng, Yu-Jie Huang, Kai-Xuan Zhang, Yu-mei You, Zheng-Yun Sun Yat Sen Univ Sch Phys Guangzhou 510275 Peoples R China Sun Yat Sen Univ Sino French Inst Nucl Engn & Technol Zhuhai 519082 Peoples R China

DD4hep serves as a generic detector description toolkit recommended for offline software development in next-generation high-energy physics (HEP) experiments. Conversely, Filmbox (FBX) stands out as a widely used 3D modeling file format within the 3D software industry. In this paper, we introduce a novel method that can automatically convert complex HEP detector geometries from DD4hep description into 3D models in the FBX format. The feasibility of this method was demonstrated by its application to the DD4hep description of the Compact Linear Collider detector and several sub-detectors of the super Tau-Charm facility and circular electron-positron collider experiments. The automatic DD4hep-FBX detector conversion interface provides convenience for further development of applications, such as detector design, simulation, visualization, data monitoring, and outreach, in HEP experiments.

关键词： Detector description DD4hep FBX Geometry Offline software PHYSICS SIMULATION

Ginsenoside Rg3 Promotes the Survival and Migration of Trophoblast Cells in a Rat Model of Gestational Hypertension by Regulating miR-100a/Insulin Growth Factor-2 Axis

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World Journal of Traditional Chinese Medicine 2024年第1期10卷 65-74页

作者： Xiu-mei Fan Li Yang Gang zhao Sen-Ye Huo Yan Gao Department of Obstetrics Xingtai Third HospitalXingtaiChina Department of Obstetrics Xingtai Maternal and Child Health Care HospitalXingtaiChina

Objective:Preeclampsia(PE)is a common complication during ***-100a is expressed in the placenta and regulates the survival and development of placental *** growth factor-2(IGF-2)may serve as its downstream *** study investigated the protective mechanisms of ginsenoside Rg3 against PE in rat *** and Methods:LPS-induced rat PE models were suitable for intravenous administration of the highly expressed miR-100a ginsenoside Rg3 lentiviral *** trophoblasts were cultured in vitro for JEG-3,and PE cell models were *** vivo effects on tumor growth and apoptosis were *** Rg3 was treated with different concentrations of shRNA,miR-100a analogs,inhibitors,or *** and the expression of autophagy-related proteins were *** activity and migration were determined using Cell Counting Kit-8 and Transwell *** drugs strongly inhibited trophoblasts under normal conditions with some synergy between ***-luciferase return assay confirmed the binding affinity of miR-100a for ***:In response to Rg3,autophagy and the expression of autophagy-related proteins LC3-I/II,Beclin1,and SQSTM1 were reduced in PE rat placental ***3 inhibited autophagy in JEG-3 cells and promoted JEG-3 survival and migration in a concentration-dependent ***-100a upregulated PE *** results suggested that autophagy was a vital signaling ***3 intervention inhibited miR-100a expression and miR-100a downregulated IGF-2 expression in placental tissues and promoted autophagy,thereby inhibiting JEG-3cell survival and *** rats,Rg3 inhibited PE development by regulating the activity of the miR-100a-IGF-2 signaling ***:Ginsenoside Rg3 positively regulates the miR-100a-IGF-2 axis and protects PE rats by inhibiting trophoblastic autophagy and promoting trophoblastic cell survival and migration.

关键词： Ginsenoside Rg3 inflammatory response miR-100a/insulin growth factor-2 axis preeclampsia pregnancy-induced hypertension

Interpretation of the Standards of Basic Dataset of Chronic Diseases Behavior Risk Factor Surveillance in Adults

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Biomedical and Environmental Sciences 2024年第5期37卷 551-556页

作者： zhao Yan Fang ZHANG mei WEI Wen Qiang SUN Ke Xin LI Xin Hua WANG Li Min National Center for Chronic and Noncommunicable Disease Control and Prevention(NCNCD) Chinese Center for Disease Control and PreventionBeijing 100050China Cancer Hospital Chinese Academy of Medical SciencesBeijing 100021China Chinese Center for Disease Control and Prevention Beijing 102206China People's Medical Publishing House Beijing 100021China

BACKGROUND China’s Behavioral Risk Factor Surveillance System(BRFSS)originated from the World Bankfunded HealthⅦLoan Project in the 1990s,which conducted behavioral risk factor surveillance in seven cities and one province^([1]).Drawing on the World Health Organization’s(WHO)STEPwise approach to surveillance(STEPs)and the *** Risk Factor Surveillance System(BRFSS)^([2,3]).

关键词： funded Basic originated

Privacy-Preserving Multi-Keyword Fuzzy Adjacency Search Strategy for Encrypted Graph in Cloud Environment

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Computers, Materials & Continua 2024年第3期78卷 3177-3194页

作者： Bin Wu Xianyi Chen Jinzhou Huang Caicai Zhang Jing Wang Jing Yu Zhiqiang zhao Zhuolin mei School of Computer and Big Data Science Jiujiang UniversityJiujiang332005China Jiujiang Key Laboratory of Network and Information Security Jiujiang332005China School of Computer and Software Nanjing University of Information Science&TechnologyNanjing210044China School of Computer Engineering Hubei University of Arts and ScienceXiangyang441053China School of Modern Information Technology Zhejiang Institute of Mechanical and Electrical EngineeringHangzhou310053China Information Center Jiangxi Changjiang Chemical Co.Ltd.Jiujiang332005China School of Mathematics and Computer Science Ningxia Normal UniversityGuyuan756099China

In a cloud environment,outsourced graph data is widely used in companies,enterprises,medical institutions,and so *** owners and users can save costs and improve efficiency by storing large amounts of graph data on cloud *** on cloud platforms usually have some subjective or objective attacks,which make the outsourced graph data in an insecure *** issue of privacy data protection has become an important obstacle to data sharing and *** to query outsourcing graph data safely and effectively has become the focus of *** query is a basic and frequently used operation in graph,and it will effectively promote the query range and query ability if multi-keyword fuzzy search can be supported at the same *** work proposes to protect the privacy information of outsourcing graph data by encryption,mainly studies the problem of multi-keyword fuzzy adjacency query,and puts forward a *** our scheme,we use the Bloom filter and encryption mechanism to build a secure index and query token,and adjacency queries are implemented through indexes and query tokens on the cloud *** proposed scheme is proved by formal analysis,and the performance and effectiveness of the scheme are illustrated by experimental *** research results of this work will provide solid theoretical and technical support for the further popularization and application of encrypted graph data processing technology.

关键词： Privacy-preserving adjacency query multi-keyword fuzzy search encrypted graph

Linear inversion of geoacoustic parameters using reflection characteristics of sediment layer with low sound speed

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Chinese Journal of Acoustics 2024年第2期43卷 133-154页

作者： LI Zhanglong HU Changqing zhao mei YANG Xuefeng Shanghai Acoustics Laboratory Chinese Academy of SciencesShangha 201815 University of Chinese Academy of Sciences Beijing 100049

In order to improve the inversion efficiency and reduce the coupling of the geoacoustic parameters, a linear inversion method of the geoacoustic parameters of sediment layer with low sound speed is proposed. Based on the reflection coefficient of the plane wave of the two-layer seafloor from the quasi-linear sound speed profile, the relationship between the different reflection characteristics and the relevant geoacoustic parameters is analyzed, including the angle of intromission and the maximum reflection loss at the angle of intromission, interference fringe, and the corresponding cost function is *** with sensitivity analysis and stepwise inversion strategy, geoacoustic parameters of sedimentary layer with low sound speed are inversed step by step. This method is applicable to the case that the sound speed gradient of the low sound speed sediment layer is constant. The method is verified by part of the measured seabed reflection loss data from the new England mud patch. The inversion results are basically consistent with the relevant trans-dimensional inversion results, the inversion error is 0.1% for the sound velocity ratio, 0.3% for the density ratio, 14.6% for the absorption coefficient, and 15.8% for the sound speed gradient. The proposed method not only effectively weakens the coupling between some geoacoustic parameters, but also gives the best estimate of the power term that determines the shape of the quasi-linear sound speed profile.

关键词： sound layer coupling

Optical encryption scheme based on spread spectrum ghost imaging

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Chinese Physics B 2023年第7期32卷 375-381页

作者：刘进芬董玥王乐赵生妹 Institute of Signal Processing and Transmission Nanjing University of Posts and TelecommunicationsNanjing 210003China NanJing Tech University Pujiang Institute Nanjing 211222China

An optical encryption(OE) scheme based on the spread spectrum ghost imaging(SSGI), named as SSGI-OE, is proposed to obtain a high security with a smaller key. In the scheme, the randomly selected row number of a Hadamard matrix of order N is used as the secure key, and shared with the authorized user, Bob, through a private channel. Each corresponding row vector of the order-N Hadamard matrix is then used as the direct sequence code to modulate a speckle pattern for the ghost imaging system, and an image is encrypted with the help of the SSGI. The measurement results from the bucket detector, named as ciphertext, are then transmitted to Bob through a public channel. The illuminating speckle patterns are also shared with Bob by the public channel. With the correct secure key, Bob could reconstruct the image with the aid of the SSGI system, whereas the unauthorized user, Eve, could not obtain any useful information of the encrypted image. The numerical simulations and experimental results show that the proposed scheme is feasible with a higher security and a smaller key. For the 32 × 32 pixels image, the number of bits sent from Alice to Bob by using SSGIOE(M = 1024, N = 2048) scheme is only 0.0107 times over a computational ghost imaging optical encryption *** the eavesdropping ratio(ER) is less than 40%, the eavesdropper cannot acquire any information of the encrypted image. The extreme circumstance for the proposed SSGI-OE scheme is also discussed, where the eavesdropper begins to extract the information when ER is up to 15%.

关键词： optical encryption ghost imaging spread spectrum correlated imaging