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Curative effect assessment of bandage contact lens in neurogenic keratitis

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International Journal of Ophthalmology(English edition) 2014年第6期7卷 980-983页

作者： Yu-Zhao Sun lei Guo Fu-sheng zhang Department of Ophthalmology the First Affiliated Hospital of China Medical University Optometry Center the First Affiliated Hospital of China Medical University

AIM: To observe the curative effect of bandage contact lens in neurogenic ***: Twenty cases of neurogenic keratitis were studied at the Department of Ophthalmology, the First Affiliated Hospital of China Medical University, between October 2012 and June 2013. These included 13 males and 7 females, aged from 35 to 88 y. Patients were voluntarily divided into an experimental group(lens wearing group, n =10) and control group(drug therapy,n =10). In experimental group patients wore silicone hydrogel bandage soft contact lens. Both groups used the following eyedrops: 0.5% levofloxacin TID; 0.5%Sodium carboxymethyl cellulose QID; fibroblast growth factor BID; ganciclovir BID [cases complicated with herpes simplex virus(HSV)]; compound tropicamide BID(cases concurrent hypopyon). The healing time of corneal ulcer and complication rates were observed in the two ***: The healing time of corneal ulcer in the experimental group was 10.80±4.44 d versus 46.70±13.88 d in the control group(P <0.05). No complications occurred in the experimental group, except for the lens falling off twice in one case, the patient recovered eight days after rewearing the lens. While in the control group, all cases vascularized, 2 cases were complicated with descemetocele that recovered with amniotic membrane transplantation and 1 case was complicated with corneal perforation that recovered by autologous conjunctival flap ***: Bandage contact lens is a safe and effective method of treating neurogenic keratitis andsignificantly shortened the healing time of corneal ulcer.

关键词： neurogenic keratitis bandage contact lens

A study of interparticulate strain in a hot-extruded SiC_p/2014 Al composite

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International Journal of Minerals,Metallurgy and Materials 2019年第4期26卷 523-529页

作者： Ying Hu Qiu-bao Ou-yang lei Yao sheng Chen Lan-ting zhang School of Materials Science and Engineering Shanghai Jiao Tong University Support Department of Research Institute (R&D Center) Baoshan Iron & Steel Co.Ltd. State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong University Materials Genome Initiative Center Shanghai Jiao Tong University

We report a correlative study of strain distribution and grain structure in the Al matrix of a hot-extruded SiC particulate-reinforced Al composite(SiC_p/2014 Al). Finite element method(FEM) simulation and microstructure characterization indicate that the grain structure of the Al matrix is affected by the interparticulate strain distribution in the matrix during the process. Both electron-backscattered diffraction(EBSD) and selected-area electron diffraction(SAED) indicated localized misorientation in the Al matrix after hot extrusion. Scanning transmission electron microscopy(STEM) revealed fine and recrystallized grains adjacent to the Si C particulate and elongated grains between the particulates. This result is explained in terms of recrystallization under an interparticulate strain distribution during the hot extrusion process.

关键词： metal-matrix composites strain distribution recrystallization grain structure

The effect of a conductive polyaniline/carbon black composite on the performance of a semiconductive layer

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High Voltage 2022年第2期7卷 233-241页

作者： Enmin Wang sheng zhang Ciyao Wang Shumei Chen Chuncheng Hao Qingquan lei Institute of Advanced Electrical Materials Qingdao University of Science and TechnologyQingdaoChina State Key Laboratory of Advanced Power Transmission Technology(Global Energy Interconnection Research Institute Co. Ltd.)BeijingChina

In this study,conductive polyaniline(PANI)ribbons were introduced to a semi-conductive layer to improve the conductivity stability of the layer during thermal expansion and enhance its ability to inhibit charge injection into the insulating *** maximise the effect of PANI,PANI and carbon black(CB)were preformed into a uniformly dispersed composite,which was then added to the polymer matrix of the semiconductive *** experimental results show that the resistivity of the semi-conductive layer containing the PANI/CB composite is more stable during thermal expansion than that of the semiconductive layer only doped with *** is attributed to the conductive CB network being enhanced by the PANI *** addition,due to the unique conductivity mechanism and high dielectric constant of PANI,the semiconductive layer has a strong ability to inhibit space charge injection into the insulating layer.

关键词： composite conductive layer

Erosion characteristics and mechanism of the self-resonating cavitating jet impacting aluminum specimens under the confining pressure conditions

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Journal of Hydrodynamics 2020年第2期32卷 375-384页

作者： Hua-lin Liao sheng-li Zhao Yan-feng Cao lei zhang Can Yi Ji-lei Niu Li-hong Zhu School of Petroleum Engineering China University of PetroleumQingdao266580China State Key Laboratory of Offshore Oil Exploitation Beijing100028China Huanghe Drilling Co. Shengli Engineering Co.SINOPECDongying257000China Orion Energy International Co. LtdBeijing100101China

In order to study the effects of the confining pressure on the erosion characteristics of the self-resonating cavitating jet under wellbore and deep-water conditions,experiments are conducted on aluminum specimens impinged by the organ pipe cavitation nozzle and the conical nozzle with the confining pressure in the range 0 MPa–10.0 ***,through the numerical simulation of the collapsing process of the cavitation bubble and the noise test,the cavitation erosion mechanism is *** experimental results show that the optimal standoff distance and the confining pressure can be obtained for the maximum erosion quantities,and the optimal standoff distance is 5 to 7 times greater than the equivalent nozzle outlet diameter and the confining pressure is about 2.0 *** the same conditions,the erosion caused by the cavitation nozzle is up to 2 times larger than that caused by the conical *** to the numerical simulation and the noise test,the cavitation erosion on the aluminum specimens is mostly caused by mechanical forces due to the high-frequency pressure pulse generated during the collapse of cavitation bubbles,while just a small part is caused by micro-jets.

关键词： Cavitating jet cavitation erosion confining pressure nozzle

金属二聚体和氮共掺杂石墨烯(Gra)M_(2)N_(6)-Gra(M=Cr-Cu)的NO_(2)吸附特性理论研究

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原子与分子物理学报 2025年第5期42卷 35-42页

作者：张展博余娇魏亚茹张轩靳鑫张子音杨保成张雷雷黄河科技学院纳米功能材料研究所郑州450063

NO_(2)是空气污染物的主要成分之一,设计和开发高效的气敏传感器对NO_(2)进行检测具有重要意义.本工作利用基于密度泛函理论(DFT)的第一性原理计算方法对不同过渡金属原子形成的金属二聚体和氮共掺杂石墨烯(Gra)M_(2)N_(6)-Gra(M=Cr-Cu)... 详细信息

NO_(2)是空气污染物的主要成分之一,设计和开发高效的气敏传感器对NO_(2)进行检测具有重要意义.本工作利用基于密度泛函理论(DFT)的第一性原理计算方法对不同过渡金属原子形成的金属二聚体和氮共掺杂石墨烯(Gra)M_(2)N_(6)-Gra(M=Cr-Cu)的NO_(2)吸附特性进行了研究.结果表明,NO_(2)分子与M_(2)N_(6)-Gra之间均存在明显的化学吸附作用.其中,Ni_(2)N_(6)-Gra和Cu_(2)N_(6)-Gra体系具备较为适中的恢复时间(分别约为5秒和14分钟),这意味着这两个体系是开发新型NO_(2)气敏材料的潜在候选者.其它体系(M_(2)N_(6)-Gra,M=Cr-Co)强的吸附作用导致恢复时间过长,从而使得它们不适合作为NO_(2)气敏材料.这一研究不仅有望为设计和开发性能优异的新型NO_(2)气敏材料提供有益理论指导,还将有益于人们深入认识M_(2)N_(6)-Gra材料的NO_(2)电催化合成NO或NH 3性能.

关键词： M_(2)N_(6)-Gra NO_(2)吸附密度泛函理论

Insulation structure design and electric field simulation of 500 kV isolation energy supply transformer for HVDC breaker

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High Voltage 2022年第1期7卷 185-196页

作者： sheng zhang Yadong Fan Qingquan lei Jianguo Wang Yuan Liu Ting Zhan School of Electrical Engineering and Automation Wuhan UniversityWuhanChina Global Energy Interconnection Research Institute Co. LtdBeijingChina Institute of Advanced Electrical Materials Qingdao University of Science and TechnologyQingdaoChina China EPRI Electric Power Engineering Co.Ltd. BeijingChina

The high‐voltage isolated energy supply transformer(HIET)is the key component of the HVDC breaker,which is used for energy transmission and the potential *** is a lack of research results that can meet engineering applications at home and *** design of a 500 kV HIET with dry‐type insulation is proposed,using 10 cascade connected 50 kV sub‐transformers(STs),which uses silicon rubber suitable for DC voltage as the main insulation ***‐voltage(HV)winding of ST adopts double‐shielding structure of coil semi‐conductive shielding and inner semi‐conductive shielding to improve electric field *** simulation analysis of an electric field at different insulation thicknesses and temperatures shows that the electric field decreases with an increase in thickness of *** the thickness is greater than 25 mm,the electric field reduction effect is significantly *** electric field is closely related to temperature,when at 20℃,the electric field between double‐shielding is relatively *** at 70℃,the inner shielding electric field is much higher than coil shielding,and undergoes obvious *** addition,the 500 kV HIET's electric field has been *** 500kV HIET prototype has been manufactured and passed the type test,and successfully applied to the 500 kV zhangbei DC grid project.

关键词： winding insulation field

Effect of Low Light on the Characteristics of Photosynthesis and Chlorophyll a Fluorescence During Leaf Development of Sweet Pepper

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Journal of Integrative Agriculture 2012年第10期11卷 1633-1643页

作者： SUI Xiao-lei MAO sheng-li WANG Li-hao zhang Bao-xi zhang Zhen-xian College of Agronomy and Biotechnology China Agricultural University Institute of Vegetables and Flowers Chinese Academy of Agricultural Sciences

Low light stress is one of the main limiting factors which influence the production of sweet pepper under protected cultivation in China. In this experiment, two genotypes of sweet pepper, ShY （low light-tolerant genotype） and 20078 （low light-sensitive genotype）, were used to study the effects of low light （photosynthetic photon flux density, PPFD was 75- 100 umol m-2 s-1, control 450-500 umol m-2 s-1） on photosynthesis during leaf development. The result indicated that under low light chlorophyll content, net photosynthetic rate （PN）, photosynthetic apparent quantum efficiency （Фi） and carboxylation efficiency （CE） of sweet pepper leaves increased gradually and decreased after reaching the maximum levels. The time to reach the peak values for all the above parameters was delayed, whereas the light compensation point （LCP） decreased gradually along with leaf expansion. The decrease in maximum quantum yield of PS II （Fv/Fm） was not observed at any stages of the leaf development under low light condition, but the actual PS II efficiency under irradiance （ФPS II） was lower accompanied by an increased non-photochemical quenching （NPQ） in young and/or old leaves compared with mature leaves. The antenna thermal dissipation （D） was a main way of heat dissipation when young leaves received excessive light energy, while the decline in photosynthetic function in senescence leaf was mostly owing to the decrease in carbon assimilation capacity, followed by a significantly increased allocation of excessive energy （Ex）. Compared with 20078, ShY could maintain higher PN, ФPS II and lower QA reduction state for a longer time during leaf development. Thus, in ShY photosynthetic efficiency and the activity of electron transport of PS II were not significantly affected due to low light stress.

关键词： sweet pepper low light photosynthetic efficiency chlorophyll fluorescence leaf development

Detection of ryanodine receptor target-site mutations in diamide insecticide-resistant Spodoptera frugiperda in China

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Insect Science 2021年第3期28卷 639-648页

作者： sheng-Lan Lv Yang Shi Jia-Cheng zhang Pei Liang lei zhang Xi-Wu Gao College of Plant Protection China Agricultural UniversityBeijingChina

Spodoptera frugiperda(Lepidoptera:Noctuidae)is a widely distributed pest of *** it invaded China in 2018,it has caused serious damage to local corn ***,an anthranilic diamide insecticide,has been widely used to control lepidopteran *** is a new allosteric modulator insecticide devel-oped based on chlorantraniliprole,so it has a similar mechanism and insecticidal *** this study,we investigated resistance levels to chlorantraniliprole and tetrachloropyramid in *** from 13 populations in *** the populations tested,the relative highest resistance to chlorantraniliprole occurred in the Guangzhou population,and the most susceptible to chlorantraniliprole was found in the Wuhan *** lethal dosage LD50 value of the Guangzhou population against chlorantraniliprole was 27.8-fold higher than that of the Wuhan *** differences were observed among 5".frugiperda populations in terms of sensitivity to *** mutations at the 14734 site of the ryanodine receptor(RyR)were found,while no mutations were found in the G4891 *** mutations were detected in only two of the 786 individuals analyzed one from the Qinzhou population and other from the Anshun population(frequency below 2%in both cases).There were no significant differences in the expression levels of RyR between Guangzhou and Wuhan *** summary,our results indicate that:(i)*** has low resistance levels to diamide insecticides in China;and(ii)the differences in relative resistance among the 13 populations analyzed are not caused by the mutations in RyR or the expression of RyR.

关键词： diamide insecticides resistance resistance risk Spodoptera frugiperda

Transfer RNA-derived small RNA serves as potential non-invasive diagnostic marker and a novel therapeutic target for acute pancreatitis

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World Journal of Gastroenterology 2025年第1期31卷 152-156页

作者： Jing zhang Chun-Lin Ou Department of Immunology School of Basic MedicineCentral South UniversityChangsha 410000Hunan ProvinceChina Department of Pathology Xiangya HospitalCentral South UniversityChangsha 410008Hunan ProvinceChina

Transfer RNA(tRNA)-derived fragments,a new type of tRNA-derived small RNA(tsRNA),can be cleaved from tRNA by enzymes to regulate target gene expression at the transcriptional and translational *** are not only degradation fragments but also have biological functions,including those in immune inflammation,metabolic disorders,and cell *** dysregulation is closely associated with multiple diseases,including various cancers and acute pancreatitis(AP).AP is a common gastrointestinal disease,and its incidence increases *** development is associated with tsRNAs,which regulate cell injury and induce inflammation,especially pyroptosis and ***,serum tRF36 has the potential to serve as a non-invasive diagnostic biomarker and leads to pancreatic acinar cell ferroptosis causing inflammation to promote *** show the characteristics of tsRNAs and their diagnostic value and function in AP,and discuss the potential opportunities and challenges of using tsRNAs in clinical applications and research.

关键词： Transfer RNA derived small RNAs Acute pancreatitis Liquid biopsy Biomarker Cell pyroptosis Ferroptosis