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Distribution and changes in hepatitis C virus genotype in China from 2010 to 2020

World Journal of Clinical Cases 2022年第14期10卷 4480-4493页

作者： Jia Yang Hui-Xin Liu Ying-Ying Su Zhi-sheng liang Hui-Ying Rao Peking University Hepatology Institute Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver DiseasesPeking University People’s HospitalBeijing 100044China Department of Clinical Epidemiology and Biostatistics Peking University People’s HospitalBeijing 100044China National Institute of Diagnostics and Vaccine Development in Infectious Diseases School of Public HealthXiamen UniversityXiamen 361000Fujian ProvinceChina Department of Global Health School of Public HealthPeking UniversityBeijing 100044China

BACKGROUND Hepatitis C virus(HCV)causes a large number of infections *** infections seem to be increasing according to a report of the World Health Organization in *** direct-acting antivirals are quite effective for most genotypes of the HCV,some genotypes fail to ***,the trend of genotype distribution is vital to better control the development of this *** To analyze the distribution and trends of the HCV genotype before and after the emergence of direct-acting antivirals in *** We searched all literature published in five electronic databases-China National Knowledge Infrastructure,Wan Fang Data,VIP Chinese Journal Database,Chinese Biomedical Literature Service System,and PubMed-from January 1,2010 to December 31,*** search strategy combined medical subject headings and free-text terms,including“hepatitis C virus”or“HCV”and“genotype”or“subtype”and“China”or“Chinese”.Additional relevant articles were searched by manual *** were extracted to build a *** of the data were totaled according to regions,periods,routes of transmission,and *** percentages in various stratifications were *** There were 76110 samples from 30 provinces included in the *** 1(G1)accounted for 58.2%of cases nationwide,followed by G2,G6,G3b,G3a,unclassified and mixed infections(17.5%,7.8%,6.4%,4.9%,1.8%,and 1.2%,respectively).The constitution of genotype varied among different regions,with G6 and G3b being more common in the south and southwest,respectively(28.1%,15.4%).The past ten years have witnessed a decrease in G1 and G2 and an increase in G3 and G6 in almost all *** drug-use population had the most abundant genotypes,with G6 ranking first(33.3%),followed by G1 and G3b(23.4%,18.5%).CONCLUSION G3 and G6 pose a new challenge for HCV *** study revealed the distribution of HCV genotypes in China over the past 10 years,providing information for HCV management strategie

关键词： Hepacivirus Genotype China Drug users Direct-acting antiviral Hepatitis C virus

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Rational self-assembly of polygonal organic microcrystals for shape-dependent multi-directional 2D optical waveguides

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Chinese Chemical Letters 2022年第6期33卷 3255-3258页

作者： Chao-Fei Xu Yue Yu Qiang Lv Chang-Cun Yan Xue-Dong Wang liang-sheng Liao Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices Institute of Functional Nano and Soft Materials(FUNSOM)Soochow UniversitySuzhou 215123China Macao Institute of Materials Science and Engineering Macao University of Science and TechnologyMacao 999078China

Micro-nano-level photonic waveguide regulation is essential for future on-chip photonic integrated systems and is still of great *** report a molecular design strategy,changing the position of the methyl substituent makes the arrangement of the three isomer molecules different in their respective *** on this strategy,three sheet-like crystals with different polygonal morphologies were prepared via solution self-assembly *** in-depth optical measurements demonstrated that these three microsheet crystals have different 2D optical waveguide performances related to the *** work provides a feasible design strategy and material preparation method for realizing precise 2D optical waveguide modulation,which lays the foundation for complex photonic integrated systems in the future.

关键词： 2D optical waveguide Polygonal organic microcrystals Optical waveguide modulation Precise self-assembly Molecular design

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Causes of surface stripe cracks of Ti–4Al–2V alloy cold-rolled sheet

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Rare Metals 2014年第5期33卷 522-526页

作者： De-Ming Huang Xiong-Fei Yang Qing-Feng Wei Yong Chen Hua Guo sheng-Long liang Ying Wang Pangang Group Research Institute Co. Ltd. State Key Laboratory of Vanadium and Titanium Resources Comprehensive Utilization

The stripe cracks which formed along rolling direction on the surface of Ti–4Al–2V alloy cold-rolled sheet were observed by stereoscope, scanning electron microscope（SEM）, and energy-dispersive spectrometer（EDS）. Morphology analysis indicates that cracks are dominantly in zigzag shape, with 10–30 mm in length and less than 10 lm in depth, and there is no evidence of crack tips. Chemical composition analysis shows that crack regions feather high oxygen concentration while smooth surface is at normal oxygen level. It is obvious that the occurrence of strip cracks is mainly related to residual oxide on the surface of Ti–4Al–2V alloy cold-rolled sheet.

关键词： Ti-4Al-2V Cold-rolled sheet Surface Stripe cracks

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Indium doped CsPbI3 films for inorganic perovskite solar cells with efficiency exceeding 17%

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Nano Research 2020年第8期13卷 2203-2208页

作者： Xiaomei Li Kaili Wang Femi Lgbari Chong Dong Wenfan Yang Chang Ma Heng Ma Zhao-Kui Wang liang-sheng Liao Institute of Functional Nano and Soft Materials(FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials and DevicesSoochow UniversitySuzhou215123China Henan Province Key Laboratory of Photovoltaic Materials College of Physics&Materials ScienceHenan Normal UniversityXinxiang453007China

In recent years,all-inorganic perovskite materials have set off a research boom owing to features,such as good thermal stability,suitable bandgap,and fascinating optical ***,the power conversion efficiency(PCE)and the ambient stability of all-inorganic perovskite solar cells still remain a ***,we investigate the effect of the addition of InI3 into CsPbI3 film on the corresponding ***3 incorporation could retard the crystallization process and control the growth rate of CsPbI3 polycrystalline films,yielding a high quality film with large grains and few *** increment in electrostatic potential and the reduction of carrier recombination enabled the open-circuit voltage of fabricated perovskite solar cell to be increased from 0.89 to 0.99 *** champion device delivered a power conversion efficiency of 17.09%,which is higher than 14.36%for the reference *** the InI3-included solar cell without any encapsulation retained 77%of its original efficiency after 860 h aging at room temperature in N2 condition.

关键词： indium doping CsPbI3 crystallization retardation stability

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Solvothermal Synthesis, Crystal Structure and Property of a Three-dimensional Fe(Ⅱ) Complex: [Fe(INAIP)(DMF)]_(n)·0.5nDMF

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Chinese Journal of Structural Chemistry 2021年第5期40卷 625-630,529页

作者： CHEN Man-sheng DENG Yi-Fang ZHANG Chun-Hua sheng liang-Bing LU Wei-Hong SUN Jun-Bin Key Laboratory of Functional Organometallic Materials Hengyang Normal UniversityCollege of Chemistry and Materials ScienceHengyangHunan 421008China

A Fe-based metal-organic framework, [Fe(INAIP)(DMF)]_(n)·0.5nDMF(1), has been synthesized by the reaction of 5-(isonicotinamido)isophthalic acid(H_(2)INAIP) with FeSO_(4)·7H_(2)O under DMF reaction solvent. Single-crystal X-ray diffraction analysis indicates that complex 1 displays a two-fold interpenetrated three-dimensional(3D) framework with sra topology. The TG, magnetic and adsorption properties of the complex were also studied.

关键词： Fe complex solvothermal synthesis crystal structure adsorption

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Effect of Interstitial Media on Segregation in Vertically Vibrated Granular Mixtures

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Chinese Physics Letters 2013年第1期30卷 112-115页

作者： YUAN Xiao-Xian LI liang-sheng WEN Ping-Ping SHI Qing-Fan ZHENG Ning School of Physics Beijing Institute of TechnologyBeijing 100081 Science and Technology on Electromagnetic Scattering Laboratory Beijing 100854

Vertically vibrated segregation behaviors of binary granular mixtures with different interstitial media are experimentally *** study the role of interstitial media on the segregation,two types of interstitial fluids are adopted and the resulting phase diagrams are *** water-immersed granular mixture exhibits two kinds of complete segregation behaviors:Brazil nut effect and sandwich patterns,at least the latter is absent in the same air-immersed ***,the segregation extent is improved remarkably for the water-immersed *** experimental observation further confirms that the effect of interstitial media on the relative motion of grains is one of the predominant mechanisms for granular segregation.

关键词： immersed Vertical effect

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Enhancing thermoelectric performance in P-type Mg_(3)Sb_(2)-based Zintls through optimization of band gap structure and nanostructuring

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Journal of Materials Science & Technology 2024年第3期170卷 25-32页

作者： Yi-bo Zhang Ji-sheng liang Chengyan Liu Qi Zhou Zhe Xu Hong-bo Chen Fu-cong Li Ying Peng Lei Miao Guangxi Key Laboratory of Information Material Engineering Research Center of Electronic Information Materials and DevicesMinistry of EducationSchool of Material Science and EngineeringGuilin University of Electronic TechnologyGuilin 541004China Guangxi Key Laboratory for Relativity Astrophysics Center on Nanoenergy ResearchGuangxi Key Laboratory of Processing for Nonferrous Metal and Featured MaterialsSchool of Physical Science&TechnologyGuangxi UniversityNanning 530004China Guangxi Key Laboratory of Precision Navigation Technology and Application Guilin University of Electronic TechnologySchool of Information and CommunicationGuilin 541004China

P-type Mg_(3)Sb_(2)-based Zintls have attracted considerable interest in the thermoelectric(TE)field due to their environmental friendliness and low ***,compared to their n-type counterparts,they show relatively low TE performance,limiting their application in TE *** this work,we simultaneously introduce Bi alloying at Sb sites and Ag doping at Mg sites into the Mg_(3)Sb_(2)to coopera-tively optimize the electrical and thermal properties for the first time,acquiring the highest ZT value of∼0.85 at 723 K and a high average ZT of 0.39 in the temperature range of 323-723 K in sample Mg_(2.94)Ag_(0.06)Sb_(1.9)Bi_(0.1).The first-principle calculations show that the codoping of Ag and Bi can shift the Fermi level into the valence band and narrow the band gap,resulting in the increased carrier concentration from 3.50×10^(17)cm^(-3)in the reference Mg 3 Sb 0.9 Bi 0.1 to∼7.88×10^(19)cm^(-3)in sample Mg 2.94 Ag 0.06 Sb 0.9 Bi *** a result,a remarkable power factor of∼778.9μW m^(-1)K^(-2)at 723 K is achieved in sample Mg 2.94 Ag 0.06 Sb 0.9 Bi ***,a low lattice thermal conductivity of∼0.48 W m^(-1)K^(-1)at 723 K is also obtained with the help of phonon scattering at the distorted lattice,point defects,and nano-precipitates in sample Mg 2.94 Ag 0.06 Sb 0.9 Bi *** synergistic effect of using the multi-element co-doping/-alloying to optimize electrical properties in Mg_(3)Sb_(2)holds promise for further improving the TE performance of Zintl phase materials or even others.

关键词： Thermoelectric materials Band engineering Nanostructuring P-type Mg_(3)Sb_(2) Ag and Bi Co-doping

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Cold Model of Coal Gas Component Concentration Distribution in Blast Furnace Raceway

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Journal of Iron and Steel Research International 2009年第6期16卷 1-6页

作者： ZHANG sheng-fu WEN liang-ying BAI Chen-guang QIU Gui-bao HU Mei-long LU Xue-wei College of Materials Science and Engineering Chongqing University Chongqing 400030 China

Primary distribution of coal gas in blast furnace raceway has an important effect on blast furnace ironmaking process. The coal gas component concentration distribution was studied experimentally using a three-dimensional cold model. The results showed that CH4 concentration diminishes along with the height increasing on vertical section of raceway, and the concentration is the highest in the bottom of raceway. CH4 concentration increases gradually *** raceway depth with the lowest concentration value in front of the tuyere. The distribution of CH4 concentration has different characteristics in different raceway zones.

关键词： blast furnace raceway coal gas component concentration distribution

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Xiao Chai Hu Tang for Liver Diseases:A Literature Review

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World Journal of Traditional Chinese Medicine 2017年第3期3卷 46-50页

作者： Yi Wang Li Li Yan-Mei Cheng sheng-liang Zhu Department of Gastroenterology Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine Clinical Research Institute of Integrated Traditional Chinese and Western Medicine Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese Medicine

The objective of this study is to summarize the pharmacological effects and the mechanisms of action of Xiao Chai Hu Tang(XCHT, Minor Bupleurum Decoction) on liver diseases, so as to give relevant researchers a valuable insight and benefit patients with hepatopathy. PubMed was used to search for and collect scientific publications related to XCHT and liver diseases from 1986 to 2016. The available scientific results or evidence were read, classified, and analyzed. XCHT showed clinical efficacy in patients with hepatic diseases including hepatitis,hepatic fibrosis, and hepatoma. The mechanisms involved the production of cytokines, the regulation of immune function, the suppression of lipid peroxidation, etc., XCHT might work on the metabolism of some medications such as tolbutamide by the regulation of gastric emptying and intragastric pH. XCHT exhibited a very low toxicity profile, such as interstitial pneumonia due to duration of medication,patients' age, and drug combination. XCHT has been a eutherapeutic supplemental remedy for liver diseases. However, many mechanisms of action and effects of XCHT on new types of liver diseases still remain unclear, so more and more animal experiments and human clinical trials are needed to obtain enough proofs for the clinical use of XCHT in new types of hepatosis such as nonalcoholic fatty liver disease and autoimmune liver disease.

关键词： Hepatic fibrosis hepatitis hepatoma interstitial pneumonia tolbutamide Xiao Chai Hu Tang(minor bupleurum decoction)

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Solution-processable through-space charge-transfer emitters via solubilizing groups modification

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npj Flexible Electronics 2022年第1期6卷 771-777页

作者： Qi Zheng Xue-Qi Wang Yang-Kun Qu Guohua Xie liang-sheng Liao Zuo-Quan Jiang Institute of Functional Nano&Soft Materials Jiangsu Key Laboratory for Carbon-Based Functional Materials&DevicesSoochow University199 Ren’ai RoadSuzhou 215123 JiangsuPR China Sauvage Center for Molecular Sciences Hubei Key Lab on Organic and Polymeric Optoelectronic MaterialsDepartment of ChemistryWuhan UniversityWuhan 430072 HubeiPR China Macao Institute of Materials Science and Engineering Macao University of Science and TechnologyTaipa999078 MacaoSARPR China

The solubility of luminescent materials is a key parameter to improve the electroluminescent performances of solution-processed organic light-emitting diodes(OLEDs).The through-space charge transfer(TSCT)materials provide an alternative to introduce the solubilizing groups(SGs)to the ***,the tert-butyl and n-hexyl groups are introduced as SGs at C7 positions of spiro structure,named C6-DMB and tBu-DMB,away from the *** has no influence on the photophysical properties of the parent TSCT *** efficient solution-processed OLEDs were demonstrated with the maximum external quantum efficiencies of 21.0%and 21.7%,*** the best of our knowledge,these are champions in the state-of-the-art solution-processed OLEDs with TSCT *** work confirmed our conjecture of constructing highly efficient soluble emitters by transforming an outstanding TSCT material from thermal evaporation to solution-processed OLEDs with SGs simply integrated on the‘bridge’linker.

关键词： emitter charge transfer

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