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GRB 210610B:The Internal and External Plateau as Evidence for the Delayed Outflow of Magnetar

Research in Astronomy and Astrophysics 2024年第7期24卷 170-180页

作者： Yi-Ning Wei Xiang-Gao Wang Da-Bin Lin Wei-Kang Zheng Liang-Jun Chen sheng-Yu Yan Shuang-Xi Yi Qi Wang Zi-Min Zhou hui-Ya Liu en-Wei Liang Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China GXU-NAOC Center for Astrophysics and Space Sciences Nanning 530004China Department of Astronomy University of CaliforniaBerkeleyCA 94720-3411USA Department of Physics and Tsinghua Center for Astrophysics(THCA) Tsinghua UniversityBeijing 100084China School of Physics and Physical engineering Qufu Normal UniversityQufu 273165China

After launching a jet,outflows of magnetar were used to account for the achromatic plateau of afterglow and the early X-ray flux plateau known as“internal plateau”.The lack of detecting magnetic dipole emission together with the energy injection feature in a single observation poses confusion until the long gamma-ray burst(GRB)210610B is *** 210610B is presented with an optical bump following an early X-ray plateau during the afterglow *** plateau followed by a steep decline flux overlays in the steadily decaying X-ray flux with indexα_(X,1)~2.06,indicating an internal origin and that can be fitted by the spin-down luminosity law with the initial plateau luminosity log_(10)L_(X)~48.29 erg s~(-1)and the characteristic spin-down timescale T~2818 s.A subsequent bump begins at~4000 s in the R band with a rising indexα_(R,1)~-0.30 and peaks at~14125 s,after which a decay indexα_(R,2)~0.87 and finally transiting to a steep decay withα_(R,3)~1.77 achieve the closure relation of the external shock for the normal decay phase as well as the magnetar spin-down energy injection phase,provided that the average value of the photon indexΓ_γ=1.80 derived from the spectral energy distributions(SEDs)between the X-ray and optical *** closure relation also works for the late X-ray *** to the traditional picture of GRB,the outflow powers the early X-ray plateau by dissipating energy internally and collides with the leading decelerating blast burst as time goes on,which could interpret the exotic feature of GRB *** carry out a Markov Chain Monte Carlo simulation and obtain a set of best parameters:■.The artificial light curve can fit the afterglow data *** that,we estimated the average Lorentz factor and the X-ray radiation efficiency of the later ejecta are 35%and 0.13%,respectively.

关键词： (stars)gamma-ray burst individual(GRB 210610B)-(stars)gamma-ray burst general-stars jets

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Cinobufotalin prevents bone loss induced by ovariectomy in mice through the BMPs/SMAD and Wnt/β-catenin signaling pathways

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Animal Models and Experimental Medicine 2024年第3期7卷 208-221页

作者： Da-zhuang Lu Li-jun Zeng Yang Li Ran-li Gu Meng-long hu Ping Zhang Peng Yu Xiao Zhang Zheng-wei Xie Hao Liu Yong-sheng Zhou Department of Prosthodontics Peking University School and Hospital of StomatologyBeijingChina National Center of Stomatology BeijingChina National Clinical Research Center for Oral Diseases BeijingChina Beijing Key Laboratory of Digital Stomatology BeijingChina Department of Cariology and endodontology Peking University School and Hospital of StomatologyBeijingChina Peking University International Cancer Institute Peking University Health Science CenterPeking UniversityBeijingChina Central Laboratory Peking University School and Hospital of StomatologyBeijingChina National engineering Research Center of Oral Biomaterials and Digital Medical Devices BeijingChina

Background:Osteoporosis is a chronic bone disease characterized by bone loss and decreased bone ***,current anti-resorptive drugs carry a risk of various *** deep learning-based efficacy prediction system(DLEPS)is a forecasting tool that can effectively compete in drug screening and prediction based on gene expression *** study aimed to explore the protective effect and potential mechanisms of cinobufotalin(CB),a traditional Chinese medicine(TCM),on bone ***:DLEPS was employed for screening anti-osteoporotic agents according to gene profile changes in primary ***-CT,histological and morphological analysis were applied for the bone protective detection of CB,and the osteogenic differentiation/function in human bone marrow mesenchymal stem cells(hBMMSCs)were also *** underlying mechanism was verified using qRT-PCR,Western blot(WB),immunofluorescence(IF),***:A safe concentration(0.25mg/kg in vivo,0.05μM in vitro)of CB could effectively preserve bone mass in estrogen deficiency-induced bone loss and promote osteogenic differentiation/function of *** BMPs/SMAD and Wnt/β-catenin signaling pathways participated in CB-induced osteogenic differentiation,further regulating the expression of osteogenesis-associated factors,and ultimately promoting ***:Our study demonstrated that CB could significantly reverse estrogen deficiency-induced bone loss,further promoting osteogenic differentiation/function of hBMMSCs,with BMPs/SMAD and Wnt/β-catenin signaling pathways involved.

关键词： BMPs/SMAD bone loss cinobufotalin hBMMSCs osteogenesis osteoporosis Wnt/β-catenin signaling pathways

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New model of linkage evolution for the transtensional fault systems in the Nanpu Sag of Bohai Bay Basin: Insight from seismic interpretation and analogue modelling

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Petroleum Science 2024年第4期21卷 2287-2310页

作者： Yu-Heng Wang Fu-sheng Yu Bao-Yin Zhao Ling-Jian Meng College of Geosciences China University of Petroleum (Beijing) State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum (Beijing) Jidong Oilfield Company PetroChina Limited Company

The evolution of faults within the same stress field is frequently influenced by numerous factors,involving the reactivation of pre-existing structures, stress transmission through ductile detachment layers, and the growth, interaction, as well as linkage of new fault segments. This study analyses a complex multi-phase oblique extension fault system in the Nanpu Sag(NPS) of the Bohai Bay Basin(BBB),China. High-resolution three-dimensional(3D) seismic data and analogue modelling indicate that the oblique extensional reactivation of pre-existing structures governs the sequential arrangement of fault segments in the caprock, and they dip synthetically to the reactivated fault at depth. During the NW-SE extension in the Eocene, the predominant movement of the pre-existing fault is strike-slip. Subsequently,during the N-S extension since the Oligocene, inclined at *** the pre-existing fault, forming splay fault segments and ultimately creating large en-echelon arcuate faults linked by relay ramps. Using fault throw-distance(T-D) and laser scanning, we reconstructed the fault evolution model of oblique extension reactivation in the presence of a ductile detachment basement. Our study illustrates that the arcuate faults can be categorized into linear master fault segments controlled by pre-existing structures, bending splay faults in the termination zone, and normal fault segments responding to the regional stress *** interaction between faults occurs among normal faults and strike-slip faults, and the kinematic unification of the two fault systems is accomplished in the intersection zone. As the faults continue to evolve, the new fault segments tend to relinquish the control of pre-existing structures and concentrate more on the development of planar and continuous major faults. The ductile detachment layer significantly contributes to the uniform distribution of strain, resulting in narrow shear zones and discontinuous normal faults in its absence.

关键词： Analogue modelling Transtensional deformation Fault linkage Fault intersection zone Nanpu Sag of Bohai Bay basin

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全局性DNA去甲基化参与男性减数分裂重组调控

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科学通报 2024年第4期69卷 476-478页

作者：陈军薛盛恩赵小阳常港深圳大学医学部深圳518060 南方医科大学基础医学院广州510515

精子发生是一个复杂的发育过程,基因突变或表观遗传变异对精子发生功能的破坏可导致男性不育[1~3].在精子发生过程中,减数分裂是生殖细胞获得遗传多样性的关键,其中涉及一系列重要事件,包括前细线期精母细胞中DNA的复制、细线期中DNA双... 详细信息

精子发生是一个复杂的发育过程,基因突变或表观遗传变异对精子发生功能的破坏可导致男性不育[1~3].在精子发生过程中,减数分裂是生殖细胞获得遗传多样性的关键,其中涉及一系列重要事件,包括前细线期精母细胞中DNA的复制、细线期中DNA双链断裂(DSBs)的形成、合子期及粗线期中发生的减数分裂重组,以及联会复合体在双线期的解离[2,4,5].随着单细胞测序技术在生殖发育领域的应用,先前的研究已初步绘制了人类精子发生过程的基因转录图谱[6~8].

关键词：男性不育联会复合体基因突变精子发生生殖发育减数分裂精母细胞细线期

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Performance Analysis and Optimization of energy Harvesting Modulation for Multi-User Integrated Data and energy Transfer

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China Communications 2024年第1期21卷 148-162页

作者： Yizhe Zhao Yanliang Wu Jie hu Kun Yang School of Information and Communication engineering University of Electronic Science and Technology of ChinaChengdu 611731China

Integrated data and energy transfer(IDET)enables the electromagnetic waves to transmit wireless energy at the same time of data delivery for lowpower *** this paper,an energy harvesting modulation(EHM)assisted multi-user IDET system is studied,where all the received signals at the users are exploited for energy harvesting without the degradation of wireless data transfer(WDT)*** joint IDET performance is then analysed theoretically by conceiving a practical time-dependent wireless *** the aid of the AO based algorithm,the average effective data rate among users are maximized by ensuring the BER and the wireless energy transfer(WET)*** results validate and evaluate the IDET performance of the EHM assisted system,which also demonstrates that the optimal number of user clusters and IDET time slots should be allocated,in order to improve the WET and WDT performance.

关键词： energy harvesting modulation(EHM) integrated data and energy transfer(IDET) performance analysis wireless data transfer(WDT) wireless energy transfer(WET)

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二氧化碳静态爆破的边坡振动场地效应和能量分析

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Journal of Central South University 2024年第1期31卷 210-224页

作者：王小飞胡少斌王恩元 School of Safety engineering China University of Mining and TechnologyXuzhou 221116China Tunnel and Underground engineering Institute College of Civil and Transportation EngineeringHohai UniversityNanjing 210098China

进行真三轴CO_(2)静态爆破压裂实验和现场测试,获得压力曲线、试样裂隙分布、现场振动曲线和岩体破坏特征,并通过分析压力曲线和裂缝扩展特征来研究致裂原理,同时还利用窗函数傅里叶变换提取振动特征,以评估破岩现场边坡的结构安全。研... 详细信息

进行真三轴CO_(2)静态爆破压裂实验和现场测试,获得压力曲线、试样裂隙分布、现场振动曲线和岩体破坏特征,并通过分析压力曲线和裂缝扩展特征来研究致裂原理,同时还利用窗函数傅里叶变换提取振动特征,以评估破岩现场边坡的结构安全。研究结果表明:(1)CO_(2)静态爆破的峰值振动速度在8 m处衰减至满足建筑物保护要求,比传统的钻爆法更安全;(2)CO_(2)静态爆破引起的振动波形的主频高于钻爆法的,且随着距离的加长,振动能量的分布逐渐分散;(3)钻爆法的振动速度预测公式适用于CO_(2)静态爆破的,且带高程的预测公式更为准确。根据压力曲线、试样裂隙分布和现场岩体损伤,提出CO_(2)静态爆破的HIG破岩模型,为新技术的研究提供了基础框架。在实验中没有采集到温度数据,今后迫切需要对聚能剂的瞬时放热特性和温度对CO_(2)状态的影响进行研究。

关键词：破岩技术二氧化碳静态爆破振动速度致裂机理能量计算

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ESCRT,病毒感染的“双刃剑”

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中国兽医科学 2024年第2期54卷 283-284页

作者： Xuefei Wang https://***/0009-0004-1077-6715 Sahibzada Waheed Abdullah Jin'en Wu Jianli Tang Yun Zhang hu Dong Manyuan Bai Sumin Wei Shiqi Sun sunshiqi@*** huichen Guo https://***/0009-0004-1077-6715 guohuichen@*** State Key Laboratory for Animal Disease Control Prevention National Foot-and-Mouth Disease Reference Laboratory Lanzhou Veterinary Research Institute Chinese Academy of Agricultural Sciences Lanzhou Gansu China State Key Laboratory for Animal Disease Control Prevention College of Veterinary Medicine Lanzhou University Lanzhou Gansu China

内体分选转运复合体(endosomalsortingcomplex required for transport,ESCRT)是细胞中一个复杂的系统,该系统在病毒感染中起着“双刃剑”的作用,即它们能够被不同家族病毒劫持用于自身增殖,也能被宿主细胞利用对抗病毒的侵染。在病毒... 详细信息

内体分选转运复合体(endosomalsortingcomplex required for transport,ESCRT)是细胞中一个复杂的系统,该系统在病毒感染中起着“双刃剑”的作用,即它们能够被不同家族病毒劫持用于自身增殖,也能被宿主细胞利用对抗病毒的侵染。在病毒生命周期的不同阶段,病毒可以通过多种方式利用或限制ESCRT系统介导的生理过程,或者直接调控ESCRT系统的各蛋白组分的表达增加感染宿主的能力。ESCRT是由20多种蛋白质组成的复合体。根据其成分及其功能差异可以分为若干个复合物,即ESCRT-0、ESCRT-Ⅰ、ESCRT-Ⅱ、ESCRT-Ⅲ.

关键词：病毒感染蛋白组分蛋白质组成宿主细胞复合体功能差异感染宿主双刃剑

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关于推理公式流量是否为设计重现期最大流量的数学模型检验探讨

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给水排水 2024年第3期50卷 70-76页

作者：王晟胡家璇同济大学环境科学与工程学院教育部长江水环境重点实验室上海200092

采用数学模型计算雨水设计流量方法发展一直受到缺乏雨水设计数学建模规范性方法的制约。有技术路线是根据推理公式建模,即建立和推理公式等效的模型。推理公式的作用是计算设计重现期最大降雨径流量,其可靠性依赖理论假设和参数取值。... 详细信息

采用数学模型计算雨水设计流量方法发展一直受到缺乏雨水设计数学建模规范性方法的制约。有技术路线是根据推理公式建模,即建立和推理公式等效的模型。推理公式的作用是计算设计重现期最大降雨径流量,其可靠性依赖理论假设和参数取值。基于教材上推理公式案例的研究表明,固定产流系数-漫流模型不能和推理公式等效。扣损法产流-漫流模型中28/31实现了和推理公式等效,用等效模型求设计重现期最大流量并与推理公式结果作比较发现,支撑推理公式的实质性假设在25个情境下被证伪,在3个情境下成立,即理论上推理公式可求得设计重现期最大流量,然而它们中只有1个求得,原因在于仅靠经验难以周全考虑降雨-漫流-产流过程来对推理公式参数取值。推理公式不能保证求得设计重现期最大流量,因此根据推理公式建模的技术路线需商榷。

关键词：城市雨水排水雨水设计流量推理公式雨水数学模型

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OsLESV and OsESV1 promote transitory and storage starch biosynthesis to determine rice grain quality and yield

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Plant Communications 2024年第7期5卷 215-230页

作者： Nannan Dong Guiai Jiao Ruijie Cao Sanfeng Li Shaolu Zhao Yingqing Duan Liuyang Ma Xinwei Li Feifei Lu Hong Wang Shiwen Wang Gaoneng Shao Zhonghua sheng Shikai hu Shaoqing Tang Xiangjin Wei Peisong hu State Key Laboratory of Rice Biology and Breeding China National Center for Rice ImprovementChina National Rice Research InstituteHangzhou 310006China

Transitory starch is an important carbon source in leaves,and its biosynthesis and metabolism are closely related to grain quality and *** molecular mechanisms controlling leaf transitory starch biosynthesis and degradation and their effects on rice(Oryza sativa)quality and yield remain ***,we show that OsLESV and OsESV1,the rice orthologs of AtLESV and AtESV1,are associated with transitory starch biosynthesis in *** total starch and amylose contents in leaves and endosperms are significantly reduced,and the final grain quality and yield are compromised in oslesv and osesv1 single and oslesv esv1 double ***,we found that OsLESV and OsESV1 bind to starch,and this binding depends on a highly conserved C-terminal tryptophan-rich region that acts as a starch-binding ***,OsLESV and OsESV1 also interact with the key enzymes of starch biosynthesis,granule-bound starch synthase I(GBSSI),GBSSII,and pyruvate orthophosphote dikiase(PPDKB),to maintain their protein stability and *** and OsESV1 also facilitate the targeting of GBSSI and GBSSII from plastid stroma to starch *** of GBSSI,GBSSII,and PPDKB can partly rescue the phenotypic defects of the oslesv and osesv1 ***,we demonstrate that OsLESV and OsESV1 play a key role in regulating the biosynthesis of both leaf transitory starch and endosperm storage starch in *** findings deepen our understanding of the molecular mechanisms underlying transitory starch biosynthesis in rice leaves and reveal how the transitory starch metabolism affects rice grain quality and yield,providing useful information for the genetic improvement of rice grain quality and yield.

关键词： transitory starch starch-binding domain starch biosynthesis leaf starch deficiency rice Oryza sativa

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基于形变长短期记忆网络的换道意图预测

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科学技术与工程 2024年第11期24卷 4769-4775页

作者：田晟胡啸华南理工大学土木与交通学院广州510641

混行交通下的自动驾驶车辆需具备换道意图预测能力来保障行驶安全。为尽早预测车辆换道意图,提出一种基于形变长短期记忆(mogrifier long short-term memory,M-LSTM)网络的换道意图预测模型。首先采用S-G(Savitzky-Golay)滤波器对自然... 详细信息

混行交通下的自动驾驶车辆需具备换道意图预测能力来保障行驶安全。为尽早预测车辆换道意图,提出一种基于形变长短期记忆(mogrifier long short-term memory,M-LSTM)网络的换道意图预测模型。首先采用S-G(Savitzky-Golay)滤波器对自然驾驶数据集NGSIM(next generation simulation)进行降噪筛选,按向左换道、向右换道、直线行驶对不同时间长度的轨迹序列标注,选取车辆运动信息与环境信息输入模型,最后采用softmax函数进行意图分类。试验结果表明,在不同预判时间下,模型准确率均高于支持向量机(support vector machine,SVM)、LSTM模型,且越接近换道点预测准确率越高,在1.0、2.5 s时预测准确率分别为93.83%与81.30%。提出的模型具有良好的准确性与预判性,能为自动驾驶车辆尽早识别换道意图提供技术支持。

关键词：自动驾驶形变长短期记忆网络车辆换道意图预测

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