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A Preliminary Study on Seismicity and Stages of Seismic Energy Accumulation in Seismotectonic Regions of Tianshan

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Earthquake Research in China 2006年第2期20卷 174-189页

作者： Li Yingzhen shen jun wang Haitao Earthquake Administration of Xinjiang Uygur Autonomous Region Urumqi 830011 China

Using seismic parameters, the characteristics of the seismic activity in various seismotectonic regions of Tiaushan were studied in this paper. These regions are going through different stages of seismic energy accumulation. Current seismic risk levels of these areas were analyzed synthetically by the tectonic movement rates, as well as the characteristics of the seismic activity and the recurrence intervals of strong earthquakes. We preliminarily studied the characteristics of seismic activity in different seismic energy accumulating stages. The result shows that the characteristics of the seismic activity in various seismotectonic regions of the Tiaushan area are influenced, not only by the regional tectonic movement, but also by the energy accumulating stage of various seismic tectonics. In the intense tectonic movement areas, it is important to estimate its stage of energy accumulating in order to predict the upper limit of the potential earthquake magnitude. In the less intense tectonic movement areas, the estimating of the stage of energy accumulation will help us recognize the dangerous level of the potential strong earthquake. The study shows that the seismotectonic regions in southern Tiaushan have reached the mid-stage and late-stage of energy accumulation, with a higher seismic activity and thus a higher seismic dangerous level than those in the northern and middle Tiaushan. The earthquake risk of southern Tianshan is up to Ms7.0, while that of the middle Tiaushan is up to Ms6.0 and that of northern Tiaushan is only around Ms5.0 - 6.0.

关键词： Tianshan Stage of the seismic energy accumulation Seismic activity

The analgesic effect of electroacupuncture in complete Freund's adjuvant rats:a meta analysis

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World Journal of Acupuncture-Moxibustion 2019年第1期29卷 15-27页

作者： Kuo ZHANG Zhi-fang XU Kai LI Xue ZHAO Bo CHEN Yi GUO shen-jun wang Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjin 300072China Experimental Acupuncture-Moxibustion Research Center Tianjin University of Traditional Chinese MedicineTianjin 301617China Acu-moxibustion and Tuina Department Tianjin University of Traditional Chinese MedicineTianjin 30767乙China Department of Gynaecology The First Teaching Hospital of Tianjin University of Traditional Chinese MedicineTianjin 300381China College of Traditional Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjin 30161China

Pain is a global problem and has been found sensitive to acupuncture. A large number of existing and newly published studies have demonstrated the analgesic effect of electroacupuncture(EA) in complete Freund's adjuvant(CFA) rat model, necessitating a new and comprehensive review. To evaluate the curative effect of EA on thermal hyperalgesia in CFA rats, and to explore parameters that influence treatment effects, studies of EA treatment on thermal hyperalgesia of CFA rat model were identified from nine databases up to june 17, 2017. Outcome measure was heat pain threshold. All the data were analyzed using Stata 14.0/MP software. 26 studies identified included 801 rats. The quality score of the studies ranged from 3 to 6, with a mean of 4.08. The effect of EA group was improvement in outcome compared with CFA group. In subgroup analyses, frequency 2, 100, 2/100 or 20-100 Hz. acupoint Huántiào(环跳GB30),Kūnlún(昆仑 BL60) +Xuánzhōng(悬钟 GB39), Zúsānlī(足三里 ST36) +BL60 or ST36+Sānyīnjiāo(三阴交SP6), retention time 20 or 30 min, treatment time for post-CFA injection immediately, the same day as CFA injection, post-CFA injection 24 or 48 h and interval 24 or 48 h all can improve the effect on CFA rat heat pain threshold. These results show that there is positive effective of EA in CFA-induced pain,different parameters have different effects on EA treatment of CFA heat hyperalgesia, however, because of the number of eligible researches and the high risk of bias, the evidence supporting this conclusion is limited.

关键词： Electroacupuncture(EA) Analgesia Complete Freund's adjuvant Rats

THE LATE QUATERNARY RIGHT LATERAL STRIKE-SLIPPING OF ZHONGDIAN—DAJU FAULT IN NORTHWEST YUNNAN, CHINA

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地学前缘 2000年第S1期7卷 302-303页

作者： shen jun,wang Yipeng[WT5,5”BX](Institute of Geology of China Seismological Bureau,Beijing 100029,China)

The Zhongdian—Daju fault is the transitional fault connecting the Kalakorum\|Jiali right lateral strike slip faulting zone and the Red River Fault, and a part of the south boundary of the eastward extrusive Tibet plateau. Field observations, associated with the analyses of the satellite images and air photographs, show that the Zhongdian—Daju fault, a 250km long fault in northwest Yunnan, is a nascent right lateral strike slip fault zone with the slip rate of 2～8mm/a. The Zhongdian—Daju fault is not a simple right lateral strike slip fault. There are several subparallel, slightly en échelon fault strands from Deqing to Yongsheng with the total length of 200km and perhaps 250km. Like the typical strike\|slip faults in this area, the morphological features of the fault, which can be seen clearly in the satellite images, are characterized as straight volleys and displaced gullies and ridges. In addition, Several Quaternary basins distribute along Zhongdian—Daju fault. The are controlled by the right lateral strike slipping of the fault in late Quaternary.

关键词： Tibet Yunnan active fault geodynamics Zhongdian—Daju fault

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美国公立高校积极差别待遇录取政策反思

教育研究 2017年第9期38卷 140-147页

作者：申素平王俊中国人民大学教育学院党总支中国人民大学教育学院北京教育科学研究院高等教育科学研究所

美国联邦最高法院在最新判决中继续维持积极差别待遇录取政策的合法地位,引出少数族裔优势群体学生从中不当受益的"奶油层"争议。仅有少数族裔之名,但无弱势状况之实,是"奶油层"的主要特征。联邦对少数族裔的正式分类不能充分体现成员... 详细信息

美国联邦最高法院在最新判决中继续维持积极差别待遇录取政策的合法地位,引出少数族裔优势群体学生从中不当受益的"奶油层"争议。仅有少数族裔之名,但无弱势状况之实,是"奶油层"的主要特征。联邦对少数族裔的正式分类不能充分体现成员内部差异,高校在追求多元化学生群体目标时过度关注少数族裔身份,政策效应累加使少数族裔优势群体学生更具入学竞争优势,是"奶油层"产生的主要原因。其造成政策积极效果难以全面惠及少数族裔弱势群体,不能充分实现源自多元化学生群体的教育利益,增加高校应对司法诉讼履行举证责任的难度等负面影响。面对司法审查压力,公立高校改进积极差别待遇录取政策时势必突出政策细化和定向准确,在分类选择的基础上细化受益标准,在全面评价的基础上复核受益资格,在常态监测的基础上定期进行调整。

关键词：美国公立高校高校录取政策积极差别待遇

“煤-水”双资源型矿井开采技术方法与工程应用

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煤炭学报 2017年第1期42卷 8-16页

作者：武强申建军王洋中国矿业大学(北京) 北京100083 国家煤矿水害防治工程技术研究中心北京100083

由于我国东、西部地区煤-水资源呈逆向分布,为解决煤炭资源安全绿色开发、水资源供给、生态环保之间的尖锐矛盾和冲突,实现煤矿区水害防治、水资源保护利用、生态环境改善的多赢目标,在阐述"煤-水"双资源型矿井开采概念与内涵的基础上,... 详细信息

由于我国东、西部地区煤-水资源呈逆向分布,为解决煤炭资源安全绿色开发、水资源供给、生态环保之间的尖锐矛盾和冲突,实现煤矿区水害防治、水资源保护利用、生态环境改善的多赢目标,在阐述"煤-水"双资源型矿井开采概念与内涵的基础上,提出了根据矿井主采煤层的具体充水水文地质条件优化开采方法和参数工艺、多位一体优化结合、井下洁污水分流分排、水文地质条件人工干预、充填开采等"煤-水"双资源型矿井开采的技术和方法。以蔚县矿区兴源矿为工程背景,提出了松散含水层下薄基岩区房式保水开采方案,建立了煤房"固支梁"力学模型,提出了基于让压理论的煤柱设计方法,修正了屈服煤柱上覆载荷计算公式。结果表明:主关键层的存在和稳定扩大压力拱的形成是屈服煤柱设计的关键,且屈服煤柱具有足够的强度支撑扩大压力拱下方的覆岩重量;采5留4、采5留5、采6留5等方案具有可靠的安全系数。

关键词：双资源型矿井保水采煤多位一体优化结合压力拱屈服煤柱

The effect of Modified Wen-Dan decoction on hippocampal astrocytes in depression model rats

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TMR Pharmacology Research 2021年第3期1卷 41-47页

作者： Li-Ping Zhang shen-jun wang Ting Xue Lei Xu Yun-Sha Zhang Ying Chen jun Yang Rui-Wen Song Xue-Yan wang Tianjin University of Chinese Medicine TianjinChina301617

Background:This study aimed to observe the effect of Modified Wen-Dan decoction on hippocampal astrocytes in depression model ***:A total of 48 rats were randomly divided into a control group,a model group,a Modified Wen-Dan decoction group(referred toas the traditional Chinese medicine group),and a fluoxetine control group(referred to as the Western medicine group).The control group was provided with a free diet and without any stimulation,while the remaining three groups were solitarily housed incombination with chronic unpredictable mild stress stimuli to replicate the depression rat *** rats were subjected to the open-field and sucrose preference experiments for behavioral observation,and q-PCR was used to detect the mRNA of specific markers of hippocampal astrocytes,glial fibrillary acidic protein,and S100 calcium-binding proteinβ(S100β)in each *** was used to observe the protein expression of glial fibrillary acidic protein and S100βin thehippocampus of rats of each ***:The behavioral results showed that,compared with the control group,the rats in the model group showed a decrease in the score of the open-field experiment and in the rate of sucrose preference(P0.05).The q-PCR results showed that the mRNA and protein expression levels of GFAP and S100βwere downregulated in the model group compared to that of the control group(P<0.05).Compared with the model group,the mRNA expression levels of glial fibrillary acidic proteinand S100βwere upregulated in the traditional Chinese medicine group as well as in the Western medicine group(P<0.05).No significant difference between the Chinese and Western medicine groups was ***:The mechanism of the

关键词： Modified Wen-Dan decoction hippocampal astrocyte Depression Chinese medicine

Expression of Obesity Hormone Leptin in Human Colorectal Cancer

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Chinese Journal of Cancer Research 2009年第2期21卷 142-146页

作者： Jin-chun Cong Xian-wei Dai Ming-yang shen jun-jiang wang Chun-sheng Chen Hong Zhang Lei Qiao Department of Colorectal Surgery Shengjing Hospital China Medical University Shenyang 110004 China

Objective： The obesity hormone, leptin, has been found to participate in the development and proliferation of normal and malignant tissues. The aim of this study was to evaluate the role of leptin in human colorectal cancer. Methods： Serum leptin levels were measured via ABC-ELLSA in 30 colorectal cancers and 24 normal controls. Leptin concentration in colorectal cancer was analyzed in terms of selected clinicopathological features and some oncogenes. Results： The mean concentration of leptin was significantly higher for colorectal cancers（3.54±1.46 ng/ml） than normal controls（2.27±0.99 ng/ml）, no gender difference was observed in this study. Leptin expression in poorly differentiated tumors was obviously lower than those in moderately and well differentiated tumors. There were no statistically significant correlations between leptin and the serum CEA and CA199 in colorectal cancers （P〉0.05）, and between leptin and the expressions of K-RAS, P53, APC, DCC genes in tumor tissues （P〉0.05）. Conclusion： Leptin is overexpressed in human colorectal cancer, which is related to the differentiation degrees of the tumor. There is no correlation between leptin expression and changes of oncogenes in colorectal cancers.

关键词： Colorectal cancer Leptin

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人多能干细胞来源可移植造血分化的研究进展

中华血液学杂志 2017年第3期38卷 257-260页

作者：沈俊王征宇程涛中国医学科学院、北京协和医学院血液学研究所、血液病医院实验血液学国家重点实验室天津300020

血液疾病目前正威胁着世界数百万人的生命健康。多数情况下，移植健康或基因修复的、具有长期移植能力的造血干细胞（HSC）是唯一的治愈方法。然而，人体HSC数量有限，体外扩增培养困难以及移植物抗宿主病等大大限制了HSC移植的应用。... 详细信息

血液疾病目前正威胁着世界数百万人的生命健康。多数情况下，移植健康或基因修复的、具有长期移植能力的造血干细胞（HSC）是唯一的治愈方法。然而，人体HSC数量有限，体外扩增培养困难以及移植物抗宿主病等大大限制了HSC移植的应用。人多能干细胞（hPSC），尤其是来源广泛、不受伦理学限制的诱导型多能干细胞（iPSC）可以经体外诱导分化生成大量可以移植的自体HSC，为恶性血液疾病的治疗带来了曙光。本文着重就hPSC分化为可移植HSC的最新进展予以论述。

关键词： SC移植造血分化干细胞来源恶性血液疾病移植物抗宿主病多能干细胞体外扩增培养造血干细胞

Hippocampal miR-182 regulates depressive-like behavior induced by chronic stress in rats

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Hippocampal miR-182 regulates depressive-like behavior induc...