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Grain boundary engineering for enhancing intergranular damage resistance of ferritic/martensitic steel P92

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Nuclear Science and Techniques 2024年第5期35卷 186-199页

作者： Lei Peng Shang-Ming Chen Jing-Yi Shi Yong-Jie Sun Yi-Fei Liu yin-Zhong shen Hong-Ya He Hui-Juan Wang Jie Tian State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China School of Materials Engineering Shanghai University of Engineering Science333 Long Teng RoadShanghai 201620China Experimental Center of Engineering and Material Science University of Science and Technology of ChinaHefei 230026China

Ferritic/martensitic(F/M)steel is widely used as a structural material in thermal and nuclear power ***,it is susceptible to intergranular damage,which is a critical issue,under service *** this study,to improve the resistance to intergranular damage of F/M steel,a thermomechanical process(TMP)was employed to achieve a grain boundary engineering(GBE)microstructure in F/M steel *** TMP,including cold-rolling thickness reduction of 6%,9%,and 12%,followed by austenitization at 1323 K for 40 min and tempering at 1053 K for 45 min,was applied to the as-received(AR)P92 *** prior austenite grain(PAG)size,prior austenite grain boundary character distribution(GBCD),and connectivity of prior austenite grain boundaries(PAGBs)were *** to the AR specimen,the PAG size did not change *** fraction of coincident site lattice boundaries(CSLBs,3≤Σ≤29)and Σ3^(n) boundaries along PAGBs decreased with increasing reduction ratio because the recrystallization fraction increased with increasing reduction *** PAGB connectivity of the 6%deformed specimen slightly deteriorated compared with that of the AR ***,potentiodynamic polarization studies revealed that the intergranular damage resistance of the studied steel could be improved by increasing the fraction of CSLBs along the PAGBs,indicating that the TMP,which involves low deformation,could enhance the intergranular damage resistance.

关键词： Grain boundary engineering Ferritic/martensitic steel Prior austenite grain boundary character distribution Grain boundary connectivity Intergranular damage resistance

Genotyping on circulating tumor DNA improves mutation detection rate in high-risk diffuse large B-cell lymphoma

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Genes & Diseases 2024年第4期11卷 116-119页

作者： Yi Xia Li Wang Jinhua Liang Haorui shen Jiazhu Wu Hua yin Yue Li Huayuan Zhu Jianyong Li Wei Xu Department of Hematology The First Affiliated Hospital of Nanjing Medical UniversityJiangsu Province HospitalNanjingJiangsu 210029China Key Laboratory of Hematology of Nanjing Medical University NanjingJiangsu 210029China Collaborative Innovation Center for Cancer Personalized Medicine NanjingJiangsu 210029China

Diffuse large B-cell lymphoma(DLBCL)is the most common lymphoma with heterogeneous clinical *** who are primarily refractory to the frontline therapy or relapse less than 12 months after diagnosis have an extremely di... 详细信息

关键词： lymphoma diagnosis clinical

PHOTOELECTRIC EFFECTS FROM COVALENTLY LINKED PHTHALOCYANINE COMPLEXES IN BOTH BLM AND SnO_2 PHOTOVOLTAIC CELL

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Chinese Chemical Letters 1992年第7期3卷 565-568页

作者： Zhi Chu BI Xin Li ZHAO Yue ying QIAN Shu yin shen Jia Yong YU Hui Jun XU Institute of Photographic Chemistry Academia Sinioa Beijing 100101

Covalently linked phthalocyanine complexes were incorporated in bilayer lipid membranes(BLN) and deposited on SnO_2 transparent electrodes, Their photovoltages were measured and compared. It has been found that a more favorable orientation and closer proximity are attained in the diad compounds between the donor (phthalocyanine)-acceptor(anthraquinone) pair than in the simple compound for efficient light-induced charge separation and transfer. The triad compound is the best among all tested compounds.

关键词： BLM PHOTOELECTRIC EFFECTS FROM COVALENTLY LINKED PHTHALOCYANINE COMPLEXES IN BOTH BLM AND SnO2 PHOTOVOLTAIC CELL SnO

X连锁视网膜劈裂症的基因治疗研究现状与进展

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中华眼底病杂志 2021年第11期37卷 891-895页

作者：张天璐沈吟武汉大学人民医院眼科中心 430060 武汉大学医学研究院 430071

X连锁视网膜劈裂症(XLRS)是一种X染色体隐性遗传视网膜疾病,以双侧视网膜受累多见。患者常表现为视力损害、内层视网膜劈裂所致黄斑区轮辐状囊样改变以及视网膜电图b波相对于a波不成比例的下降。目前针对此病尚无有效的治疗方法,通常以... 详细信息

X连锁视网膜劈裂症(XLRS)是一种X染色体隐性遗传视网膜疾病,以双侧视网膜受累多见。患者常表现为视力损害、内层视网膜劈裂所致黄斑区轮辐状囊样改变以及视网膜电图b波相对于a波不成比例的下降。目前针对此病尚无有效的治疗方法,通常以并发症的治疗为主。近年来随着人们对XLRS认识的不断加深,腺相关病毒(AAV)介导的基因治疗成为了干预该病潜在的新途径。目前有两项XLRS基因治疗临床试验正在开展。这两项临床试验评估了重组AAV-RS1载体的眼部安全性和耐受性,同时探索了其在XLRS患者中使用的安全剂量,但XLRS患者视网膜结构和功能的恢复情况并不理想。相信随着各项研究的深入和临床试验的进展,未来有望为XLRS患者提供更精准有效的治疗。

关键词：视网膜劈裂症基因疗法综述

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非成像视觉环路对生理活动和行为的调控作用

中华实验眼科杂志 2023年第2期41卷 192-195页

作者：袁满(综述) 沈吟(审校) 武汉大学人民医院眼科中心武汉430060 武汉大学医学研究院武汉430071

视网膜神经节细胞(RGCs)是视网膜视觉信号输出到大脑的终极神经元,可参与成像视觉(IFV)(图像形成)和非成像视觉(NIFV)(非图像形成)。视觉处理系统除了传递图像的视觉信息外,传入的光信号对人的生理活动和行为也会产生影响,称为NIFV。NIF... 详细信息

视网膜神经节细胞(RGCs)是视网膜视觉信号输出到大脑的终极神经元,可参与成像视觉(IFV)(图像形成)和非成像视觉(NIFV)(非图像形成)。视觉处理系统除了传递图像的视觉信息外,传入的光信号对人的生理活动和行为也会产生影响,称为NIFV。NIFV较少依赖于传统光感受器细胞产生的信号,而是由视网膜上一类特殊的视网膜感光神经节细胞(ipRGCs)来完成。ipRGCs是RGCs中一类能表达感光黑视蛋白的细胞,其轴突投射至特定核团,参与调控多种NIFV行为,从基础生理调节(如心率和瞳孔大小)到更复杂的行为调节(如昼夜节律),甚至更高层次的认知过程(如焦虑等情绪)。NIFV环路是对光的重要反应,ipRGCs在NIFV环路中起着至关重要的作用。本文就NIFV环路对生理活动和行为的调控作用进行综述,归纳ipRGCs投射核团与NIFV功能的关系,以期为临床医生提供更加全面的视觉认识。

关键词：视网膜神经节细胞视觉环路生理活动行为非成像视觉

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变邻域搜索求解公共交通乘务调度问题

交通运输系统工程与信息 2017年第1期17卷 164-170页

作者：彭琨琨沈吟东华中科技大学自动化学院武汉430074

公共交通乘务调度问题是一个将车辆工作切分为一组合法班次的过程,它是NP难问题,许多求解方法的效率都与班次评价密不可分,本文通过裁剪TOPSIS方法(Technique for Order Preference by Similarity to an Ideal Solution)设计了TOPSIS班... 详细信息

公共交通乘务调度问题是一个将车辆工作切分为一组合法班次的过程,它是NP难问题,许多求解方法的效率都与班次评价密不可分,本文通过裁剪TOPSIS方法(Technique for Order Preference by Similarity to an Ideal Solution)设计了TOPSIS班次评价方法.此外,通过裁剪变邻域搜索算法使之适合求解乘务调度问题,提出了基于变邻域搜索的乘务调度方法(Crew Scheduling Approach Based on Variable Neighbourhood Search,VNS),其中,并入了TOPSIS班次评价方法在调度过程中进行班次评价,设计了两种带概率的复合邻域结构以增加搜索的多样性,帮助跳出局部最优,在VNS中利用模拟退火算法进行局部搜索.利用中国公共交通中的11组实例进行了测试,测试结果表明,VNS优于两种新近提出的乘务调度方法,且其结果关于班次数接近于下界.

关键词：城市交通乘务调度变邻域搜索复合邻域结构班次评价

Cow-YOLO:Automatic cow mounting detection based on non-local CSPDarknet53 and multiscale neck

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International Journal of Agricultural and Biological Engineering 2024年第3期17卷 193-202页

作者： De Li Junhao Wang Zhe Zhang Baisheng Dai Kaixuan Zhao Weizheng shen Yanling yin Yang Li College of Electrical Engineering and Information Northeast Agricultural UniversityHarbin 150030China College of Agricultural Equipment Engineering Henan University of Science and TechnologyLuoyang 471023HenanChina College of Animal Sciences and Technology Northeast Agriculture UniversityHarbin 150030China Key Laboratory of Northeast Smart Agricultural Technology of Ministry of Agriculture and Rural Affairs Northeast Agricultural UniversityHarbin 150030China

Cows mounting behavior is a significant manifestation of estrus in *** timely detection of cows mounting behavior can make cows conceive in time,thereby improving milk production of cows and economic benefits of the *** methods of mounting behavior detection are difficult to achieve precise detection under occlusion and severe scale change environments and meet real-time ***,this study proposed a Cow-YOLO model to detect cows mounting *** meet the needs of real-time performance,YOLOv5s model is used as the baseline *** order to solve the problem of difficult detection of cows mounting behavior in an occluded environment,the CSPDarknet53 of YOLOv5s is replaced with Non-local CSPDarknet53,which enables the network to obtain global information and improves the model’s ability to detect the mounting ***,the neck of YOLOv5s is redesigned to Multiscale Neck,reinforcing the multi-scale feature fusion capability of model to solve difficulty detection under dramatic scale ***,to further increase the detection accuracy,the Coordinate Attention Head is integrated into ***,these improvements form a novel cow mounting detection model called Cow-YOLO and make Cow-YOLO more suitable for cows mounting behavior detection in occluded and drastic scale changes ***-YOLO achieved a precision of 99.7%,a recall of 99.5%,a mean average precision of 99.5%,and a detection speed of 156.3 f/s on the test *** with existing detection methods of cows mounting behavior,Cow-YOLO achieved higher detection accuracy and faster detection speed in an occluded and drastic scale-change ***-YOLO can assist ranch breeders in achieving real-time monitoring of cows estrus,enhancing ranch economic efficiency.

关键词： cows mounting automatic detection Cow-YOLO computer vision CSPDarknet53 multiscale neck