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A retrospective study of echocardiographic cardiac function and structure in adolescents with congenital scoliosis

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Chinese Medical Journal 2009年第8期122卷 906-910页

作者： LIANG Jin-qian QIU Gui-xing shen Jian-xiong LEE Chia-I WANG Yi-peng ZHANG Jian-guo ZHAO Hong Department of Orthopedics Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100730 China

Background Patients with congenital scoliosis often also have intraspinal abnormalities and other organ defects, and few studies of the effects of congenital scoliosis on cardiac function and structure have been published. Methods A total of 215 adolescent patients with congenital scoliosis （average age, 13.58 years） underwent preoperative echocardiography and were then assigned to subgroups according to apex vertebral rotation, side of convexity, curvature severity in the coronal and sagittal planes, type of deformity, and sex. Differences between the subgroups were compared by independent-samples ttest or a one-factor analysis of variance. Results We observed statistically significant differences between patients with right-sided scoliosis curvature and those with left-sided scoliosis curvature, respectively, in left ventricular inner diameter at end-diastole （（39.39±4.66）mm vs （41.74±4.90）mm）, left ventricular inner diameter at end-systole （（24.80±3.45）mm vs （25.92±3.07）mm）, interventricular septum thickness at end-diastole （（5.66±0.98）mm vs （5.98±1.03）mm）, and posterior wall of left ventricle at end-diastole （（5.61±0.98）mm vs （6.06±1.20）mm）. When the patients were evaluated by coronal plane Cobb angle, significant differences were found between those with Cobb angle of 40°-80° and of 〉80° in left ventricular inner diameter at end-diastole （（40.97±5.06）mm vs （38.98±4.45）mm） and left ventricular inner diameter at end-systole （（25.53±3.39）mm vs （24.36±3.14）mm）, respectively. When the patients were evaluated by sagittal plane Cobb angle （〈20°, group 1; 20°-40°, group 2; 〉40°, group 3）, significant differences were found in right ventricular diameter between those with Cobb angle of 〈20° and of 20°-40° （（18.27±3.66）mm vs （16.54±3.57）mm） and in diameter of aortic root between those with Cobb angle of 20°-40° and of 〉40° （（23.83±3.39）mm vs （24.90±3.30）mm）, respectively. No significant differences were found in ejection fraction and fractional shortening between patient

关键词： congenital scoliosis echocardiography heart ventriculat function, left

神人以和:对原始乐的通神功能及思想意义之分析

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南昌大学学报（人文社会科学版） 2005年第5期36卷 76-80页

作者：熊申英中山大学哲学系广东广州510275

乐在我国原始氏族社会时期就已经产生了。从原始乐的具体运用来说,总是与人的物质活动、祭祀活动、图腾信仰以及人的情感宣泄联系在一起,乐作为通神工具,借助历史分析及文献记载和考古发现,从乐在祭祀活动中所具有的巫术性的通神功能的... 详细信息

乐在我国原始氏族社会时期就已经产生了。从原始乐的具体运用来说,总是与人的物质活动、祭祀活动、图腾信仰以及人的情感宣泄联系在一起,乐作为通神工具,借助历史分析及文献记载和考古发现,从乐在祭祀活动中所具有的巫术性的通神功能的角度,可以揭示原始人对如何解决人与人、人与自然之间的问题所作出的思考。

关键词：原始乐通神神人以和

Toosendanin: upgrade of an old agent in cancer treatment

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Chinese Journal of Natural Medicines 2024年第10期22卷 887-899页

作者： LI Shuwei xiong Qingyi shen Yiwen LIN Jiayi ZHANG Lijun WU Ye JIN Jinmei LUAN Xin Shanghai Frontiers Science Center for Chinese Medicine Chemical Biology Institute of Interdisciplinary Integrative Medicine Research and Shuguang Hospital Shanghai University of Traditional Chinese Medicine

Toosendanin(TSN), a tetracyclic triterpenoid derived from Melia toosendan and M. azedarach, demonstrates broad application prospects in cancer treatment. Although previously employed as a pesticide, recent studies have revealed its potential therapeutic value in treating various types of cancer. TSN exerts an anticancer effect via mechanisms including proliferation inhibition, apoptosis induction, migration suppression, and angiogenesis inhibition. However, TSN's toxicity, particularly its hepatotoxicity, significantly limits its therapeutic application. This review explored the dual nature of TSN, evaluating both its anticancer potential and toxicological risks, emphasizing the importance of balancing these aspects in therapeutic applications. Furthermore, we investigated the incorporation of TSN into novel therapeutic strategies, such as Proteolysis-targeting chimeras(PROTAC) technology and nanotechnology-based drug delivery systems(DDS), which enhance treatment efficacy while mitigating toxicity in normal tissues.

关键词： Cancer therapy Hepatotoxicity Nano-delivery systems PROTAC Toosendanin

货币政策冲击、短期经济增长与通货膨胀预期管理

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陕西师范大学学报（哲学社会科学版） 2016年第4期45卷 122-130页

作者：刘明谌亦雄陕西师范大学西北历史环境与经济社会发展研究院/金融研究所陕西西安710062

借鉴埃斯特雷亚(Estrella)和哈多维利斯(Hardouvelis)的方法检验中国国债长短期利差对宏观经济增长的预测能力,结果表明长短期利差对未来1—5个月和15—17个月的宏观经济增长变动具有显著预测能力。应用VAR模型获取货币政策冲击信息,将... 详细信息

借鉴埃斯特雷亚(Estrella)和哈多维利斯(Hardouvelis)的方法检验中国国债长短期利差对宏观经济增长的预测能力,结果表明长短期利差对未来1—5个月和15—17个月的宏观经济增长变动具有显著预测能力。应用VAR模型获取货币政策冲击信息,将长短期利差分解为货币政策冲击因素和非货币政策冲击因素,考察长短期利差预测能力的影响因素,发现长短期利差的短期预测能力主要受货币政策冲击因素影响,中期预测能力主要受非货币政策冲击因素影响。表明央行实施影响国债长短期利差的货币政策可以间接影响短期宏观经济增长预期。对于金融市场主体,可以通过观察短期货币政策变动对国债长短期利差的影响预测短期经济增长趋势。研究结果表明,货币当局应重视通胀预期管理,并将利率期限结构作为货币政策预期管理的重要工具。

关键词：国债长短期利差宏观经济景气指数货币政策冲击经济增长预期管理

3D printed multicore fiber-tip discriminative sensor for magnetic field and temperature measurements

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Light(Advanced Manufacturing) 2024年第1期5卷 82-92页

作者： Cong xiong Caoyuan Wang Ruowei Yu Wei Ji Yu Qin Yichun shen Wei Chen Ai-Qun Liu Limin Xiao Advanced Fiber Devices and Systems Group Key Laboratory of Micro and Nano Photonic Structures(MoE)Key Laboratory for Information Science of Electromagnetic Waves(MoE)Shanghai Engineering Research Center of Ultra-Precision Optical ManufacturingSchool of Information Science and TechnologyFudan UniversityShanghaiChina Zhongtian Technology Advanced Materials Co. Ltd.NantongJiangsuChina Key laboratory of Specialty Fiber Optics and Optical Access Networks Joint International Research Laboratory of Specialty Fiber Optics and Advanced CommunicationShanghai University.ShanghaiChina Department of Electrical and Electronic Engineering The Hong Kong Polytechnic UniversityHong KongChina

Miniaturized fiber-optic magnetic field sensors have attracted considerable interest owing to their superiorities in anti-electromagnetic interference and ***,the intrinsic thermodynamic properties of the material make temperature cross-sensitivity a challenging problem in terms of sensing accuracy and *** this study,an ultracompact multicore fiber(MCF)tip sensor was designed to discriminatively measure the magnetic field and temperature,which was subsequently evaluated *** novel 3D printed sensing component consists of a bowl-shaped microcantilever and a polymer microfluid-infiltrated microcavity on the end-facet of an MCF,acting as two miniaturized Fabry-Perot *** magnetic sensitivity of the microcantilever was implemented by incorporating an iron micro ball into the microcantilever,and the microfluid-infiltrated microcavity enhanced the capability of highly sensitive temperature *** this tiny fiber-facet device in the two channels of an MCF allows discriminative measurements of the magnetic field and temperature by determining the sensitivity coefficient matrix of two *** device exhibited a high magnetic field intensity sensitivity,approximately 1805.6 pm/mT with a fast response time of~213 ms and a high temperature sensitivity of 160.3 pm/℃.Moreover,the sensor had a low condition number of 11.28,indicating high reliability in two-parameter *** proposed 3D printed MCF-tip probes,which detect multiple signals through multiple channels within a single fiber,can provide an ultracompact,sensitive,and reliable scheme for discriminative *** bowl-shaped microcantilever also provides a useful platform for incorporating microstructures with functional materials,extending multi-parameter sensing scenarios and promoting the application of MCFs.

关键词： Two-photon polymerization Multicore fiber-tip sensor Magnetic field sensing Discriminative sensing

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浅谈搪瓷场致发光屏的生产

玻璃与搪瓷 2000年第4期28卷 28-34页

作者：白杰沈永雄兴达搪瓷厂广东南海528244

叙述了通过大量实验而得出的生产搪瓷场致发光屏的生产工艺及技术要求 ,对该技术含量较高的搪瓷产品的相关技术作了较为透彻的分析及深入的描述。

关键词：搪瓷场致发光屏光强发光搪瓷

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水泥熟料自粉化模型

上海建材学院学报 1991年第2期4卷 142-149页

作者：张雄沈威同济大学

本文根据能量转换及应力传递原理,描述了熟料的自粉化模型。通过XRD定量分析β-C2S→γ→C2S的转晶量（[γ—C2S]）、BET（N2）吸附法测定粉化前后熟料比表面积增量（△S）、双液接触角法测定熟料比表面能（γ）等试验导出了自粉化模型... 详细信息

本文根据能量转换及应力传递原理,描述了熟料的自粉化模型。通过XRD定量分析β-C2S→γ→C2S的转晶量（[γ—C2S]）、BET（N2）吸附法测定粉化前后熟料比表面积增量（△S）、双液接触角法测定熟料比表面能（γ）等试验导出了自粉化模型的三个定量表达式,即:粉化效应比表面积方程、转晶应力方程和比表面积增量与转晶应力（σ）关系式。应用自粉化模型关系式,又导出了熟料矿物组成设计和自粉化效应节能效益估算两个经验公式。由自粉化模型求得的节能效益估算及熟料组成设计值与实验结果基本相符,从而验证了自粉化模型的合理性。

关键词：水泥熟料自粉化模型

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裂步法最小二乘偏移

地球物理学进展 2012年第2期27卷 761-770页

作者：沈雄君刘能超杭州地波工程物探技术有限公司杭州310000 恒泰艾普石油天然气技术服务股份有限公司北京100084

最小二乘偏移的核心思想是用正向传播算子的逆算子代替其共轭转置算子进行偏移.它克服了常规偏移方法用共轭转置算子偏移的缺点.本文详细地描述了裂步法最小二乘偏移的原理,实现算法,并通过两个模型展示了裂步法最小二乘偏移的可行性和... 详细信息

最小二乘偏移的核心思想是用正向传播算子的逆算子代替其共轭转置算子进行偏移.它克服了常规偏移方法用共轭转置算子偏移的缺点.本文详细地描述了裂步法最小二乘偏移的原理,实现算法,并通过两个模型展示了裂步法最小二乘偏移的可行性和有效性.并且通过研究发现最小二乘较容易被扩展到基于其它波场延拓算子的最小二乘偏移.

关键词：最小二乘偏移裂步法偏移共轭转置算子逆算子

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X舵潜器水动力特性及主动增稳技术研究

中国造船 2023年第5期64卷 185-195页

作者：林兆伟宋江峰李旺申雄武汉第二船舶设计研究所武汉430064

利用潜器航行运动监测系统的运动反馈,提出3种运动跟踪控制因子,以及确定舵等效稳定性系数的方法。以X型舵的操纵特性为研究对象,建立了X舵与十字舵等效舵力分配方法。根据水动力试验数据建立操纵性运动方程,设计了融合主动增稳控制的... 详细信息

利用潜器航行运动监测系统的运动反馈,提出3种运动跟踪控制因子,以及确定舵等效稳定性系数的方法。以X型舵的操纵特性为研究对象,建立了X舵与十字舵等效舵力分配方法。根据水动力试验数据建立操纵性运动方程,设计了融合主动增稳控制的算法。仿真计算结果满足控制稳定和机动指标的综合要求,可为潜器水动力综合性能多目标优化创造条件。

关键词： X舵水动力试验等效舵力运动反馈稳定性设计主动增稳