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ANIMAL NUTRITION 2024年第3期18卷 203-219页

作者： Yuan, Hang Xie, Minghua Chen, Jian Hu, Naijie Wang, Honming Tan, Beiping shi, Lili Zhang, Shuang Guangdong Ocean Univ Coll Fisheries Zhanjiang Peoples R China Chinese Acad Trop Agr Sci Zhanjiang Expt Stn Zhanjiang Peoples R China Dalian Ocean Univ Coll Fisheries & Life Sci Dalian Peoples R China

Aiming to investigate the impact of different stocking densities on the ability of Pacific white shrimp (Litopenaeus vannamei) to utilize Chlorella sorokiniana (CHL), a 3 x 2 factorial design stocking experiment was used in this study. Specifically, shrimp was fed with two dietary protein sources (fishmeal [FM] and CHL) at low (LSD; 100 per m(3)), medium (MSD; 200 per m3) and high (HSD; 300 per m3) stocking densities for 8 weeks. The growth performance and resistance to Vibrio parahaemolyticus (1.0 x 107 CFU/ mL) of shrimp decreased with the increase of stocking density, but dietary CHL improved this result. Differences between the CHL and FM groups for V. parahaemolyticus resistance were significant only under high-density conditions (P po), and the contents of malondialdehyde (MDA) in the hepatopancreas and the activities of intestinal amylase, most of which were significantly different between CHL and FM groups only at high stocking density (P potential as a novel protein source in the intensive farming of shrimp. (c) 2024 The Authors. Publishing services by

关键词： Chlorella sorokiniana Stocking density Microbiota structure Transcriptomic profile Litopenaeus vannamei CLARIAS-GARIEPINUS BURCHELL GROWTH-PERFORMANCE BODY-COMpoSITION RAINBOW-TROUT SPIRULINA-PLATENSIS ENZYME-ACTIVITIES MEAL REPLACEMENT FEED-UTILIZATION PROTEIN-SOURCES IMMUNE

Genome-wide and candidate gene association studies identify BnPAP17 as conferring the utilization of organic phosphorus in oilseed rape

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Journal of Integrative Agriculture 2024年第4期23卷 1134-1149页

作者： Ping Xu Hao Li Haiyuan Li Ge Zhao shengjie Dai Xiaoyu Cui Zhenning Liu Lei shi Xiaohua Wang College of Agriculture and Forestry Science Linyi UniversityLinyi 27600China National Key Laboratory of Crop Genetic Improvement/Microelement Research Centre/Key Laboratory of Arable Land Conservation(Middle and Lower Reaches of Yangtze River) Ministry of Agriculture and Rural Affairs/Huazhong Agricultural UniversityWuhan 430070China

Phosphorus(P)is essential for living plants,and P deficiency is one of the key factors limiting the yield in rapeseed production *** the most important organ for plants,root morphology traits(RMTs)play a key role in P *** investigate the genetic variability of RMT under low P availability,we dissected the genetic structure of RMTs by genome-wide association studies(GWAS),linkage mapping and candidate gene association studies(CGAS).A total of 52 suggestive loci were associated with RMTs under P stress conditions in 405 oilseed rape *** purple acid phosphatase gene BnPAP17 was found to control the lateral root number(LRN)and root dry weight(RDW)under low P *** expression of BnPAP17 was increased in shoot tissue in P-efficient cultivars compared to root tissue and P-inefficient cultivars in response to low P ***,the haplotype of BnPAP17^(Hap3)was detected for the selective breeding of P efficiency in oilseed ***-expression of the BnPAP17^(Hap3)could promote the shoot and root growth with enhanced tolerance to low P stress and organic phosphorus(po)utilization in oilseed ***,these findings increase our understanding of the mechanisms underlying BnPAP17-mediated low P stress tolerance in oilseed rape.

关键词： genome-wide association studies(GWAS) root morphology traits(RMTs) organic phosphorus(po) oilseed rape BnPAP17

SBAS-InSAR技术融合CNN-LSTM模型的矿区开采沉陷监测与预测

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安全与环境学报 2024年第9期24卷 3429-3438页

作者：师芸折夏雨张雨欣王凯张琨吴睿西安科技大学测绘科学与技术学院西安710054 自然资源部煤炭资源勘查与综合利用重点实验室西安710021 西安科技大学建筑与土木工程学院西安710054 广州南方测绘科技股份有限公司广州510000

针对传统矿区开采沉陷监测方法耗费人力财力和预测预警模型较少的问题,研究提出一种基于短基线集合成孔径雷达干涉测量(Small Baseline Subset-Interferometry Synthetic Aperture Radar,SBAS-InSAR)技术和卷积神经网络(Convolutional N... 详细信息

针对传统矿区开采沉陷监测方法耗费人力财力和预测预警模型较少的问题,研究提出一种基于短基线集合成孔径雷达干涉测量(Small Baseline Subset-Interferometry Synthetic Aperture Radar,SBAS-InSAR)技术和卷积神经网络(Convolutional Neural Networks,CNN)与长短期记忆网络(Long Short-Term Memory,LSTM)相结合的矿区开采沉陷监测预测方法。首先,利用SBAS-InSAR技术对建新煤矿进行矿区开采沉陷监测,获取了该矿区的年平均沉降速率和累计沉降值。用GNSS监测数据与SBAS-InSAR结果进行对比验证,其拟合效果较好。其次,在此基础上利用CNN-LSTM模型预测后6期沉降数据,其结果与CNN和LSTM预测结果进行对比。研究显示,CNN-LSTM模型的平均绝对误差(S_(MAE))和均方根误差(S_(RMSE))比单一的CNN和LSTM分别至少降低了44.8%和40.6%,其决定系数均高于98%。最后,进一步预测前6期和中6期沉降数据,验证了CNN-LSTM预测模型在时间上的一致性。因此,SBAS-InSAR融合CNN-LSTM模型在类似矿山开采沉陷监测和预测中有较好的应用前景。

关键词：安全工程短基线集合成孔径雷达干涉测量(SBAS-InSAR) 开采沉陷卷积神经网络-长短期记忆(CNN-LSTM)模型沉降预测

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石墨烯的形貌特征对其场发射性能的影响

物理学报 2024年第8期73卷 227-236页

作者：郑钦仁詹涪至折俊艺王建宇石若立孟国栋西安交通大学电工材料电气绝缘全国重点实验室西安710049 国网四川省电力公司天府新区供电公司成都610095

石墨烯具有优异的电学、热学和力学特性以及丰富的电子隧穿边缘,是场发射阴极的良好材料.本文通过调控化学气相沉积法制备石墨烯的生长参数,分别制备了单层石墨烯薄膜、石墨烯岛、有缓冲层石墨烯等3种形貌石墨烯,探究了石墨烯的形貌特... 详细信息

石墨烯具有优异的电学、热学和力学特性以及丰富的电子隧穿边缘,是场发射阴极的良好材料.本文通过调控化学气相沉积法制备石墨烯的生长参数,分别制备了单层石墨烯薄膜、石墨烯岛、有缓冲层石墨烯等3种形貌石墨烯,探究了石墨烯的形貌特征对其场发射性能的影响,并结合COMSOL多物理场仿真分析了石墨烯的形貌特征对其场发射性能的影响机制.实验结果表明,相比于单层石墨烯薄膜,石墨烯岛和有缓冲层石墨烯的开启场强分别降低至5.55 V/μm和5.83 V/μm,最大场发射电流密度也分别提升至40.3μA/cm^(2)和26.4μA/cm^(2).另一方面,在基底上连续分布的单层石墨烯薄膜和有缓冲层石墨烯场发射电流更稳定,在5 h的测试中,电流密度分别仅下降2%和4%.结合仿真结果可知,石墨烯的形貌特征对其场发射过程中的电场分布特性和散热能力具有重要的影响.石墨烯岛和有缓冲层石墨烯存在边界结构,使得场发射过程中局部电场集中,进而提升了场发射性能.石墨烯岛在基底上离散分布,未形成连续石墨烯薄膜,缺乏焦耳热横向散热通道,热量的积累将导致石墨烯岛发射体受到损伤,并影响其场发射电流稳定性.本文探究了石墨烯的形貌特征对其场发射性能的影响,并分析了相关影响机制,对石墨烯材料场发射性能的提高具有重要的意义.

关键词：石墨烯形貌场发射 COMSOL 多物理场耦合

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Necrolytic migratory erythema caused by pancreatic hyperglycemia with emphasis on therapeutic and prognosis:A case report

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World Journal of Clinical Cases 2024年第23期12卷 5404-5409页

作者： shi-Ping Zhan Department of Dermatology General Hospital of the Yangtze River ShippingWuhan Brain HospitalWuhan 430000Hubei ProvinceChina

BACKGROUNDWith the incidence of pancreatic diseases increasing year by year,pancreatichyperglycemia,as one of the common complications,is gradually gaining attentionfor its impact on the skin health of *** SUMMARYThis was the case of an elderly female with clinical manifestations of necrolyticmigratory erythema,“three more and one less,”diabetes mellitus,hypertension,anemia,hypoproteinemia,and other syndromes,which had been misdiagnosedas *** computed tomography showed a pancreatic caudal spaceoccupyinglesion,and the magnetic resonance scanning of the epigastric regionwith dynamic enhancement and diffusion-weighted imaging suggested a tumorof the pancreatic tail,which was considered to be a neuroendocrine tumor *** patient was referred to a more equipped hospital for laparoscopicpancreatic tail ***-surgery diagnosis revealed a neuroendocrinetumor in the tail of the *** date,the patient’s general condition is good,and she is still under close *** migratory erythema can be induced by endocrine system tumors orendocrine metabolic abnormalities,with complex clinical manifestations,difficultdiagnosis,and easy misdiagnosis by *** initial treatment principlesin dermatology include symptomatic supportive therapy and effectivedrugs to relieve skin *** clarifying the etiology of glucagonoma,comprehensive treatment in collaboration with endocrinologists,generalsurgeons,and oncologists can help provide individualized treatment for patientsand improve their prognosis.

关键词： Glucagonoma Necrolytic loosening of wandering erythema Treatment Prognosis

冷弯薄壁型钢-结构防火一体板自攻螺钉连接性能试验研究

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土木与环境工程学报（中英文） 2024年第3期46卷 134-143页

作者：熊刚折志伟李环宇石宇刘宜丰姜雪重庆大学土木工程学院、山地城镇建设与新技术教育部重点试验室重庆400045 中国建筑西南设计研究院有限公司成都610041

开展冷弯薄壁型钢-结构防火一体板自攻螺钉连接抗剪性能试验研究,完成35个典型试件单调拉伸及低周往复加载试验,分析结构防火一体板厚度、螺钉直径、螺钉端距及加载角度等因素对其抗剪性能的影响。结果表明:不同加载角度及螺钉端距的试... 详细信息

开展冷弯薄壁型钢-结构防火一体板自攻螺钉连接抗剪性能试验研究,完成35个典型试件单调拉伸及低周往复加载试验,分析结构防火一体板厚度、螺钉直径、螺钉端距及加载角度等因素对其抗剪性能的影响。结果表明:不同加载角度及螺钉端距的试件呈现不同的破坏模式,主要包括板材端部撕裂破坏、板材孔壁承压破坏、板材被拉断破坏等,且破坏时试件的自攻螺钉存在不同程度的倾斜。对于试验端分别采用直径为4.8、5.5 mm螺钉的试件,试件的峰值荷载及延性系数与螺钉直径无明显相关性,弹性刚度随着螺钉直径增大而显著提升;随着螺钉端距由15 mm增大至25 mm,试件的弹性刚度无明显变化,而峰值荷载和延性系数提高了约35%;随着板厚由12 mm增大到20 mm,试件的峰值荷载提高了约40%,弹性刚度提高了约90%,延性系数降低了约30%;与加载角度为0°的试件的特征参数相比,加载角度为45°时,试件弹性刚度提高了约100%,峰值荷载及延性系数无明显差别;加载角度为90°时,试件弹性刚度及峰值荷载无明显差别,延性系数降低了约40%。

关键词：冷弯薄壁型钢结构防火一体板螺钉连接抗剪性能低周往复荷载

Brasilicardin A生物合成相关二萜合酶的异源表达及产物鉴定

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药学学报 2024年第7期59卷 2161-2170页

作者：葛祥宇周广鑫熊娜卢姿含米芯雨朱枝祥刘晓王晓晖王娟史社坡北京中医药大学中药现代研究中心北京102488 中国医学科学院、北京协和医学院药物研究所天然药物活性物质与功能国家重点实验室北京100050

从致病性放线菌Nocardia brasiliensis IFM 0406中得到的二萜糖苷brasilicardin A,因免疫抑制活性显著、毒性较低且作用机制独特而成为新型免疫抑制剂的候选分子。由于原菌株中产率低,且结构复杂、化学合成困难,brasilicardin A及其类... 详细信息

从致病性放线菌Nocardia brasiliensis IFM 0406中得到的二萜糖苷brasilicardin A,因免疫抑制活性显著、毒性较低且作用机制独特而成为新型免疫抑制剂的候选分子。由于原菌株中产率低,且结构复杂、化学合成困难,brasilicardin A及其类似物的获得成为该类新型免疫抑制剂的研究热点。根据目前报道的brasilicardin A可能的生物合成途径,通过生物信息学分析生物合成相关二萜合酶,定向从致病菌株*** IFM 0406中扩增可能合成brasilicardin A骨架的基因bra1~5,在白色链霉菌Streptomyces albus R1中成功实现异源表达。通过液体发酵培养,利用硅胶柱色谱及半制备液相色谱等方法进行化合物的分离纯化,共分离到6个新brasilicardins化合物,命名为brasilicardin H~M。利用脂多糖(LPS)活化的小鼠原代巨噬细胞炎症模型对分离鉴定的brasilicardins进行了体外活性筛选,结果显示,brasilicardin H~M具有较强抑制巨噬细胞释放一氧化氮(NO)的作用,IC_(50)分别为28.24±3.70、37.44±2.00、39.85±4.02、26.77±4.40、65.25±1.48、15.24±2.72μmol·L^(-1)(阳性对照吲哚美辛IC_(50)为34.28±4.10μmol·L^(-1)),表明6个化合物具有潜在的抗炎活性。本研究为brasilicardin A生物合成途径的彻底阐明提供了条件,也为研究该类化合物的构效关系、药物研发等奠定了基础。

关键词： brasilicardin A 二萜合酶异源表达免疫抑制活性

Influence of Heat-setting Temperature on the Microporous Structure and Properties of PP/HDPE Bilayer Microporous Membranes

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Chinese Journal of polymer Science 2024年第8期42卷 1243-1252页

作者： Jie Xie Yong-shi Wu Jia-Yi Xie Rui-Jie Xu Cai-Hong Lei Sai-Nan Song Guang-Quan Li An-Ping Huang School of Materials and Energy Guangdong University of TechnologyGuangzhou 510006China Lanzhou Petrochemical Research Center Petrochemical Research InsititutePetroChinaLanzhou 730060China School of Chemistry and Civil Engineering Shaoguan CollegeShaoguan 512005China

Due to the mechanical stability of PP layer,the PP/HDPE double-layer microporous mem brane could be prepared at a higher heat-setting temperatu re than that of PE monolayer *** this work,the effects of heat-setting temperature on the pore structure and properties of PP/HDPE dou ble-layer membrane were *** the increase of heat-setting temperature from 120℃to 130℃,the length of connecting bridge crystal and crystallinity in the PE layer increase due to the melting of thin lamellae and the stability of connecting bridge structure during *** corresponding air permeability,po rosity,wetta bility of liquid electrolyte and mechanical property of the heat-set microporous membrane increase,exhibiting better electrochemical ***,when the heat-setting temperature is further increased to 140℃,higher than the melting point of PE resin,some pores are closed since the lamellae and connecting bridges melt and shrink during heat-setting,resulting in a decrease of air permeability and *** contrast,there is negligible change in the PP layer within the above heat-setting temperature *** study successfully builds the relationship between the stable pore structure and property of microporous membrane during heat-setting,which is helpful to guide the production of high-pe rformance PP/PE/PP lithium batteries separator.

关键词： PP/HDPE bilayer microporous membranes Heat-setting temperature SAXS

Massive simultaneous hepatic and renal perivascular epithelioid cell tumor benefitted from surgery and everolimus treatment:A case report

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World Journal of Gastrointestinal Surgery 2024年第10期16卷 3334-3342页

作者： Han-Teng Yang Fu-Rong Wang Na He Yuan-Hua she Yong-Yue Du Wen-Gui shi Jing Yang Gang Chen Shu-Ze Zhang Feng Cui Bo Long Ze-Yuan Yu Jun-Min Zhu Geng-Yuan Zhang Department of General Surgery Lanzhou University Second HospitalLanzhou 730030Gansu ProvinceChina Department of Pathology Lanzhou University Second HospitalLanzhou 730030Gansu ProvinceChina Oncology Department Ward Lanzhou University Second HospitalLanzhou 730030Gansu ProvinceChina Cuiying Biomedical Research Center Lanzhou University Second HospitalLanzhou 730030Gansu ProvinceChina

BACKGROUND Perivascular epithelioid cell tumor(PEComa)is a rare mesenchymal neoplasm that predominantly affects the kidney and *** occurrence of this tumor in the liver,particularly with simultaneous involvement of the liver and kidney,is exceedingly *** diagnosis is the gold *** usually show positive immunohistochemical staining for melanocytic(HMB-45,Melan-A)and myoid(SMA,muscle-specific actin)*** SUMMARY We presented a noteworthy case of malignant PEComa affecting both the liver and kidney in a 53-year-old man with tuberous sclerosis complex(TSC).FAT2 and TP73 mutations in the kidney were identified and positive expression of diagnostic markers including HMB-45,Melan A,and TFE3 were *** addition,we demonstrated that hepatic artery perfusion chemotherapy was ineffective for hepatic PEComa,while surgery remained the most effective *** showed an excellent efficacy in the postoperative treatment of the *** Surgical treatment is preferred for malignant PEComa affecting liver and kidney,especially with TSC;everolimus is effective postoperatively.

关键词： Perivascular epithelioid cell tumor Hepatic Renal Surgery Case report

Construction of coal pitch-based HA-K grafted poly condensates and their excellent anti-temperature and viscosity-reducing properties

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Petroleum Science 2024年第4期21卷 2806-2816页

作者： Jing Tan Wei Zhang Xiu-Ling Yan Hao Zhou sher Bahadar Khan Seitkhan Azat shi-You Yan Hao-Jie Ma Xin-Tai Su Xinjiang Key Laboratory of Clean Conversion and High Value Utilization of Biomass Resources College of Chemistry and Chemical Engineering Yili Normal University School of Environment and Energy Guangdong Provincial Key Laboratory of Solid Wastes Pollution Control and Recycling South China University of Technology Drilling Fluid Branch of CNPC Xibu Drilling Engineering Company Limited Department of Chemistry Faculty of Science King Abdulaziz University PO Box 80203 Faculty of Chemistry and Chemical Technology Al-Farabi Kazakh National University Urumchi Huatailong Chemical Additives Co. Ltd.

Humic acids(HAs) are widely used as filtrate and viscosity reducers in drilling fluids. However, their practical utility is limited due to poor stability in salt resistance and high-temperature resistance. Hightemperature coal pitch(CP) is a by-product from coal pyrolysis above 650.C. The substance's molecular structure is characterized by a dense arrangement of aromatic hydrocarbon and alkyl substituents. This unique structure gives it unique chemical properties and excellent drilling performance, surpassing traditional humic acids in drilling operations. potassium humate is prepared from CP(CP-HA-K) by thermal catalysis. A new type of high-quality humic acid temperature-resistant viscosity-reducer(Graft CP-HA-K polymer) is synthesized with CP-HA-K, hydrolyzed polyacrylonitrile sodium salt(Na-HPAN),urea, formaldehyde, phenol and acrylamide(AAM) as raw materials. The experimental results demonstrate that the most favorable conditions for the catalytic preparation of CP-HA-K are 1 wt% catalyst dosage, 30 wt% KOH dosage, a reaction temperature of 250.C, and a reaction time of 2 h, resulting in a maximum yield of CP-HA-K of 39.58%. The temperature resistance of the Graft CP-HA-K polymer is measured to be 177.39.C, which is 55.39.C higher than that of commercial HA-K. This is due to the abundant presence of amide, hydroxyl, and amine functional groups in the Graft CP-HA-K polymer,which increase the length of the carbon chains, enhance the electrostatic repulsion on the surface of solid particles. After being aged to 120.C for a specified duration, the Graft CP-HA-K polymer demonstrates significantly higher viscosity reduction(42.12%) compared to commercial HA-K(C-HA-K). Furthermore,the Graft CP-HA-K polymer can tolerate a high salt concentration of 8000 mg.L-1, measured after the addition of optimum amount of 3 wt% Graft CP-HA-K polymer. The action mechanism of Graft CP-HA-K polymer on high-temperature drilling fluid is that the Graft CP-HA-K polymer can increase the re

关键词： Viscosity breaker Heat resistance Base mud Graft CP-HA-K polymer CP Salt resistance