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世界核心医学期刊文摘（胃肠病学分册） 2006年第1期2卷 7-8页

作者： Khatami s.s. Khandwala F. shay s.s. Vaezi M.F. 徐小洁 Department of Gastroenterology and Hepatology Center for Swallowing and Esophageal Disorders Cleveland Clinic Foundation 9500 Euclid Avenue Cleveland OH 44195 United States Dr.

Diffuse esophageal spasm (DEs) and achalasia share both clinical and manometric characteristics. some reports.s.pport the notion of progression of DEs to achalasia. However, there are currently no prospective data in support of this theory. To ass.s. prospectively the rate of manometric progression of DEs to achalasia. Manometry tracings of DEs patients diagnosed between 1992 and 2003 were independently reviewed blindly and agreed on by two esophageal experts. Patients with DEs who agreed to undergo repeat esophageal manometry constituted the study cohort. Follow- up manometry tracings were evaluated blindly and independently by the same two interpreters to determine the rate of manometric progression to achalasia. Predictors of manometric progression were ass.s.ed. A total of 32 patients were diagnosed with DEs between 1992- 2003. Twelve patients (9M/3F;median age 62 years) agreed to participate and underwent second manometry (mean ± sD follow- up of 4.8± 3.4 years). Achalasia was diagnosed on follow- up manometry in one patient (8% ), seven (58% ) patients continued to have DEs, three (25% ) had normal motility, and one (8% ) had nutcracker esophagus. There were no predictors of progression to achalasia based on the initial manometry parameters. A subgroup of DEs patients with initial low esophageal body amplitude developed increase in esophageal simultaneous contractions on follow- up similar to the patient who evolved to achalasia. Following were the results. 1) Progression from DEs to achalasia is uncommon. 2)DEs patients with low esophageal body amplitude may develop increased simultaneous contractions over time. 3) DEs remains an elusive diagnos.s.clinically and manometrically.

关键词：食管失弛缓症弥漫性食管痉挛前瞻性队列研究压力测定单盲收缩运动胡桃夹病程发展重复测定

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Bioreactor design and validation for manufacturing strategies in tissue engineering

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Bio-Design and Manufacturing 2022年第1期5卷 43-63页

作者： Diana Lim Eric s.Renteria Drake s.s.me Young Min Ju Ji Hyun Kim Tracy Criswell Thomas D.shupe Anthony Atala Frank C.Marini Metin N.Gurcan shay soker Joshua Hunsberger James J.Yoo Wake Forest Institute for Regenerative Medicine Wake Forest School of MedicineWinston-SalemNC 27157USA Center for Biomedical Informatics Wake Forest School of MedicineWinston-SalemNC 27157USA RegenMed Development Organization(ReMDO) Winston SalemNC 27106USA

The fields of regenerative medicine and tissue engineering offer new therapeutic options to restore,maintain or improve tissue function following disease or *** maximize the biological function of a tissue-engineered clinical product,specific conditions must be maintained within a bioreactor to allow the maturation of the product in preparation for ***,the bioreactor should be designed to mimic the mechanical,electrochemical and biochemical environment that the product will be exposed to in ***-time monitoring of the functional capacity of tissue-engineered products during manufacturing is a critical component of the quality management *** present review provides a brief overview of bioreactor engineering *** addition,strategies for bioreactor automation,in-line product monitoring and quality assurance are discussed.

关键词： Bioreactor Monitoring sensors and automation Manufacturing Tissue engineering Regenerative medicine

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从BEAT到sHIELD再到UTPR:美国反避税措施的嬗变之策

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国际税收 2022年第5期 12-20页

作者：胡天龙 shay s.Moyal 朱春妮中国人民大学财政金融学院美国纽约达维律师事务所广州宝洁有限公司

数字经济所带来的商业模式和价值创造模式的变革,使跨国企业更容易对其业务进行时间与空间上的调整,也进一步加剧了全球税基侵蚀问题。如何通过国际税收协作应对数字经济下的税基侵蚀,已经成为国际税收治理新秩序关注的全球性议题。“... 详细信息

数字经济所带来的商业模式和价值创造模式的变革,使跨国企业更容易对其业务进行时间与空间上的调整,也进一步加剧了全球税基侵蚀问题。如何通过国际税收协作应对数字经济下的税基侵蚀,已经成为国际税收治理新秩序关注的全球性议题。“税基侵蚀与反滥用税”(Base Erosion and Anti-abuse Tax,BEAT)作为美国在2017年颁布的《减税与就业法案》(Tax Cut and Job Act,TCJA)中设立的新税种,其原理与数字经济下国际税收治理趋势有相似之处,但其与TCJA设定的其他新国际税收规则不同,并无任何先前法律和提案中的预设,且其机制和条文在实施时表现出一定的模糊或待定之处。随着二十国集团/经济合作与发展组织(G20/OECD)主导的税基侵蚀和利润转移(BEPs)包容性框架下“双支柱”国际税收新规则的进展,以及美国内政的动荡,BEAT规则细节不断更新,从“停止有害倒置及结束低税收发展(sHIELD)提案”的提出,到被提议取消、由支柱二方案下的“低税支付规则”(UTPR)所代替,折射出美国处理国际税收利益时的被动和妥协,但BEAT在维护税收原则、规范税则细节和协调税收协定等层面对我国国际税收治理改革仍有一定积极意义。

关键词：税基侵蚀与反滥用税停止有害倒置及结束低税收发展低税支付规则税基侵蚀和利润转移国际税收治理全球最低税

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Total Intravenous Anesthesia (TIVA) for stiff-Person syndrome

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Open Journal of Anesthesiology 2012年第4期2卷 185-187页

作者： Fiore V. Toscano Angela K.Vick Hamilton H. shay Ellise s. Delphin Departmentof Anesthesiology Albert Einstein College of Medicine / Montefiore Medical Center Bronx USA

stiff-Person syndrome is a rare autoimmune neurologic disorder that affects the central nervous.s.stem by inhibiting production of the neurotransmitter gamma-aminobutyric acid. Painful muscle spas.s.and rigidity are the clinical manifestations of the disease. An ideal anesthetic technique has not been described for this patient population because of the rarity of the disease. This case report describes the successful use of total intravenous anesthesia in a patient with stiff- Person syndrome.

关键词： stiff-Person syndrome stiff-Man syndrome Total Intravenous Anesthesia (TIVA)

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simultaneous Hashing of Multiple Messages

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Journal of Information security 2012年第4期3卷 319-325页

作者： shay Gueron Vlad Krasnov Department of Mathematics University of Haifa Haifa Israel Intel Corporation Israel Development Center Haifa Israel

We describe a method for efficiently hashing multiple messages of different lengths. such computations occur in various.s.enarios, and one of them is when an operating s.s.em checks the integrity of its components during boot time. These tas.s.can gain performance by parallelizing the computations and using sIMD architectures. For such scenarios, we compare the performance of a new 4-buffers.s.A-256 s-HAsH implementation, to that of the standard serial hashing. Our results are measured on the 2nd Generation Intel? CoreTM Processor, and demonstrate sHA-256 processing at effectively ~5.2 Cycles per Byte, when hashing from any of the three cache levels, or from the s.s.em memory. This represents.s.eedup by a factor of 3.42x compared to OpenssL (1.0.1), and by 2.25x compared to the recent and faster n-s.s.method. For hashing from a disk, we show an effective rate of ~6.73 Cycles/Byte, which is almost 3 times faster than OpenssL (1.0.1) under the same conditions. These results indicate that for some usage models, sHA-256 is.s.gnificantly faster than commonly perceived.

关键词： sHA-256 sHA-512 sHA3 Competition sIMD Architecture Advanced Vector Extensions Architectures AVX AVX2

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Make the univent tube more effective in one lung ventilation

Make the univent tube more effective in one lung ventilation

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2006年中华医学会全国麻醉学术年会

作者： Hamilton shay Alexandra Bastien Department of Anesthesiology Montefiore Medical Center111 E 210th streetBronxNew York 10467 U．S．A．

This brief report describes a simple way to improve the Univent tube in one lung ventilation. Modified connection tubing is applied, which make effective suction possible through the bronchial block port and deliberately collaps.s.the non -dependent lung faster. It may help to shunt the blood to the dependent lung within a shorter period of time. This type of suction may also make it easier to remove blood or secretion within the bronchus of the nondependent lung.

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阻抗法、检压法及pH探针法在就餐前后检测反流的直接比较

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世界核心医学期刊文摘（胃肠病学分册） 2006年第1期2卷 6-7页

作者： shay s. Richter J. 徐小洁 Cleveland Clinic Foundation 9500 Euclid Avenue Cleveland OH 44195 United States Dr.

Combining GERD tes.s.allows.s.rengths and weakness.s.of each method to be identified in detecting and characterizing reflux (RE). Aim of this.s.udy was to compare two methods that measure bolus volume of a refluxant (impedance monitoring (Imp) and manometry (common cavity)) to pH monitoring which measures changes in acid concentration of a refluxant. Nineteen symptomatic GERD patients and 10 normal volunteers were studied before and after a meal. All had 2- hr simultaneous manometry, pH, and Imp (six sites: 3, 5, 7, 9, 15, 17 cm above LEs). Reflux by pH was a fall in pH from above to below 4. There were 973 RE’ s in all subjects, but only 19% were detected simultaneously by all three methods. Imp detected more RE’ s (96% ) than manometry (76% ) or pH probe (28% ). Imp was the only method to detect 15% (144/973) of RE’ s, while detection only by pH probe (2% ) or manometry (2% ) was rare. Most RE’ s detected by Imp were detected simultaneously by manometry (75% ,720/937). Those not detected by manometry were usually in blind spots either in the vulnerable period 2- 3 sec after a swallow, during a posture change, or during a Valsalva. Most RE’ s detected by Imp were not detected by the pH probe. Though most liquid RE’ s fasting were detected by pH, most liquid postprandial RE’ s were not, due primarily to weakly acidic rather than superimposed acid RE’ s. Bolus clearing time by Imp and manometry was nearly identical, while acid clearing was threefold longer than bolus clearing by Imp or manometry. In conclusion, impedance monitoring is better than manometry and pH monitoring in RE detection before and after a meal, and manometry in determining RE composition as liquid or gas. The pH probe measures RE acidity and acid clearing. simultaneous impedance and pH combines the two methods.s.rengths, and is a powerful tool for reflux detection and characterization.

关键词：检压法 pH 阻抗法探针法胃食管反流监测法酸浓度清除率程中定性的

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Estimation of successful capping with complete aspiration of bladder via nephroureterostomy tube

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World Journal of Clinical Urology 2020年第1期9卷 1-8页

作者： Majid Maybody Wesley K shay Deborah A Fleischer Meier Hsu Chaya Moskowitz Department of Radiology Interventional Radiology ServiceMemorial Sloan Kettering Cancer CenterNew YorkNY 10065United States Department of Biostatistics and Epidemiology Memorial Sloan Kettering Cancer CenterNew YorkNY 10065United States

BACKGROUND Ureteral stent and nephroureterostomy tube(NUT)are treatments of ureteral *** stent provides better quality of *** of NUT is desired whenever *** To ass.s. outcomes of capping trial among cancer patients with complete aspiration of retained contrast from bladder via *** Our Institutional Review Board approved retrospective review of all NUT placement,NUT exchange and conversion of nephrostomy catheter into NUT performed during June 2013 to June 2015(n=578).Cas.s.were excluded due to lack of imaging of bladder(n=37),incomplete aspiration of bladder(n=324),no attempt at capping NUT(n=166),and patients with confounding factors interfering with results of capping trial including non-compliant bladder,bladder outlet obstruction and catheter malposition(n=14).study group cons.s.ed of 37 procedures in 34 patients(male 19,female 15,age 2-83 years,average 58,median 61)most with cancer(prostate 8,endometrial 5,bladder 4,colorectal 4,breast 2,gastric 2,neuroblastoma 2,cervical 1,ovarian 1,renal 1,sarcoma 1,urothelial 1 and testicular 1)and one with Crohn’s *** records were reviewed to ass.s. outcomes of capping *** 95%confidence intervals(95%CI)were *** Among patients with complete aspiration of retained contrast,30(81%,95%CI:0.65-0.92)catheters were successfully capped(range 12-94 d,average 40,median 24.5)until planned conversion to internal stent(23),routine exchange(5),removal(1)or death unrelated to catheter(1).seven capping trials(19%,95%CI:0.08-0.35)were unsuccessful(range 2-22 d,average 12,median 10)due to leakage(3),elevated creatinine(2),fever/hematuria(1)and nausea/vomiting(1).CONCLUsION Capping trial success among patients with complete aspiration of retained contrast/urine from bladder via NUT appears high.

关键词： Nephroureterostomy tube Ureteral stent Capping trial Internalization Conversion Percutaneous nephrostomy

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有创造力的螃蟹

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中学生英语 2024年第29期 26-29页

作者： shay Maunz 长庚不详

塑料无处不在。据联合国称,每天有足够装满2000辆垃圾车的塑料垃圾被倒入海洋、河流和湖泊等水道。海底和珠穆朗玛峰顶都有塑料垃圾。现在在另一个令人惊讶的地方发现了塑料:寄居蟹的背上。根据2月份发表在《整体环境科学》杂志上的一... 详细信息

塑料无处不在。据联合国称,每天有足够装满2000辆垃圾车的塑料垃圾被倒入海洋、河流和湖泊等水道。海底和珠穆朗玛峰顶都有塑料垃圾。现在在另一个令人惊讶的地方发现了塑料:寄居蟹的背上。根据2月份发表在《整体环境科学》杂志上的一项研究,寄居蟹正在使用塑料垃圾作为外壳。苏珊娜·雅盖隆是波兰华沙大学的科学家。她是这项研究的主要作者。“对我来说,一只住在塑料壳里的寄居蟹可能是我们这个时代的标志。”雅盖隆告诉《儿童时代》,“它们没有家,所以它们用垃圾做房子。”雅盖隆研究人类世时代,就是我们现在所处的地质时代。科学家们认为这是人类活动对环境产生重大影响的时期。寄居蟹用塑料垃圾做壳就是这种影响的一个例子。

关键词：塑料垃圾人类世波兰华沙儿童时代苏珊娜垃圾车整体环境珠穆朗玛峰

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YouTube改变了我的生活

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疯狂英语（新悦读） 2017年第4期 18-21页

作者：旭文 shay Carl Butler 不详

我有一个家庭沃客频道，名叫“谢伊一家人”。在我上传的第一个视频中，我确实穿着老婆的旧紧身衣在跳舞。人们常常将我们称为“YouTube第一家庭”。“我们是一家人，我们将每天的生活拍成视频。”我们是第一个这样做的家庭。人们点开... 详细信息

我有一个家庭沃客频道，名叫“谢伊一家人”。在我上传的第一个视频中，我确实穿着老婆的旧紧身衣在跳舞。人们常常将我们称为“YouTube第一家庭”。“我们是一家人，我们将每天的生活拍成视频。”我们是第一个这样做的家庭。人们点开我们的视频观看，然后会说：“哇，这是个很真实的家庭。他们一家人在一起闹，挺有趣的。”就这样，他们毫无防备地看上瘾了，甚至于他们都不知道自己为什么会上瘾，也不知道自己为什么要看我家的视频。

关键词： YouTube 生活家庭视频跳舞

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