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Non-surgical management of dens invaginatus type IIIB in maxillary lateral incisor with three root canals and 6-year follow-up:A case report and review of literature

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World Journal of Clinical Cases 2022年第33期10卷 12240-12256页

作者： Suraj Arora Gurdeep Singh Gill Shahabe Abullais Saquib Priyanka Saluja Suheel M Baba Shafait Ullah Khateeb Anshad M Abdulla shashit shetty bavabeedu Ahmed Babiker Mohamed Ali Mohamed Fadul A Elagib Department of Restorative Dental Sciences College of DentistryKing Khalid UniversityAbha 61421Saudi Arabia Department of Conservative Dentistry and Endodontics JCD Dental CollegeSirsa 125055India Department of Periodontics and Community Dental Sciences King Khalid UniversityAbha 61421Saudi Arabia Department of Pediatric Dentistry and Orthodontic Sciences King Khalid UniversityAbha 61421Saudi Arabia

BACKGROUND The presence of dens invaginatus(DI)complicates treatment of any tooth,from diagnosis to access cavity and biomechanical preparation and *** of successful non-surgical management of DI type IIIB in maxillary lateral incisor are ***,we report such a case,with three root canals and a long *** SUMMARY A 13-year-old female patient presented with mild pain in the maxillary right lateral incisor(#7)for 10-15 *** examination,the tooth was slightly rotated,with slight tenderness on percussion and grade I mobility but with no caries,pockets or restorations and non-vital pulp(via vitality tests).Radiographic examination revealed unusual configuration of the tooth’s root canals,with an enamel-lined invagination extending to the apex,suggesting the possibility of DI Oehler’s type IIIB and a periapical *** the access cavity lingually revealed one distinct buccal orifice and two distinct palatal orifices;under higher magnification of a dental operating microscope(DOM),the mesio palatal and disto-palatal orifices were observed as connected by a C-shaped *** root canals were prepared with hand K-files following a step-back technique,and obturated using a combination technique of lateral condensation and vertical *** the 6-year follow-up,the patient was asymptomatic,and the periapical radiography displayed significant healing around the apical end of the *** Proper knowledge of unusual root canal anatomy is required in treating *** methods of root canal treatment can successfully resolve such complex cases,facilitated by DOM and cone-beam computed tomography.

关键词： Dens invaginatus Maxillary lateral incisor Three root canals Root canal Anatomy Treatment Case report

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Exploring nitrogen reduction reaction mechanisms in electrocatalytic ammonia synthesis:A comprehensive review

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Journal of Energy Chemistry 2024年第5期92卷 681-697页

作者： Abhishek Umesh shetty Ravi Sankannavar School of Chemical and Materials Science Indian Institute of Technology GoaFarmagudiPonda 403401GoaIndia Department of Chemical Engineering M.S.Ramaiah Institute of TechnologyMSR NagarMSRIT PostBengaluru 560054KarnatakaIndia

The electrochemical nitrogen reduction reaction(eNRR)holds significant promise as a sustainable alternative to the conventional large-scale Haber Bosch process,offering a carbon footprint-free approach for ammonia *** the process is thermodynamically feasible at ambient temperature and pressure,challenges such as the competing hydrogen evolution reaction,low nitrogen solubility in electrolytes,and the activation of inert dinitrogen(N_(2))gas adversely affect the performance of ammonia *** hurdles result in low Faradaic efficiency and low ammonia production rate,which pose obstacles to the commercialisation of the *** have been actively designing and proposing various electrocatalysts to address these issues,but challenges still need to be resolved.A key strategy in electrocatalyst design lies in understanding the underlying mechanisms that govern the success or failure of the electrocatalyst in driving the electrochemical *** mechanistic studies,we gain valuable insights into the factors affecting the reaction,enabling us to propose optimised designs to overcome the *** review aims to provide a comprehensive understanding of the various mechanisms involved in eNRR on the electrocatalyst *** delves into the various mechanisms such as dissociative,associative,Mars-van Krevelen,lithium-mediated nitrogen reduction and surface hydrogenation mechanisms of nitrogen *** unravelling the intricacies of eNRR mechanisms and exploring promising avenues,we can pave the way for more efficient and commercially viable ammonia synthesis through this sustainable electrochemical process by designing an efficient electrocatalyst.

关键词： Green ammonia synthesis Electrolysis Electrocatalysis Nitrogen reductionreaction Electrochemical reaction pathways Reactionmechanism

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Diabetic cardiomyopathy:Emerging therapeutic options

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World Journal of Diabetes 2024年第8期15卷 1677-1682页

作者： Cornelius James Fernandez Sahana shetty Joseph M Pappachan Department of Endocrinology&Metabolism Pilgrim HospitalUnited Lincolnshire Hospitals NHS TrustBoston PE219QSUnited Kingdom Department of Endocrinology Kasturba Medical CollegeManipal Academy of Higher EducationManipal 576104KarnatakaIndia Department of Endocrinology and Metabolism Lancashire Teaching Hospitals NHS TrustPreston PR29HTUnited Kingdom Faculty of Science Manchester Metropolitan UniversityManchester M156BHUnited Kingdom Faculty of Biology Medicine and HealthThe University of ManchesterManchester M139PLUnited Kingdom

Diabetic cardiomyopathy(DbCM)is a common but underrecognized complication of patients with diabetes mellitus(DM).Although the pathobiology of other cardiac complications of diabetes such as ischemic heart disease and cardiac autonomic neuropathy are mostly known with reasonable therapeutic options,the mechanisms and management options for DbCM are still not fully *** its early stages,DbCM presents with diastolic dysfunction followed by heart failure(HF)with preserved ejection fraction that can progress to systolic dysfunction and HF with reduced ejection fraction in its advanced stages unless appropriately *** from prompt control of DM with lifestyle changes and antidiabetic medications,disease-modifying therapy for DbCM includes prompt control of hypertension and dyslipidemia inherent to patients with DM as in other forms of heart diseases and the use of treatments with proven efficacy in HF.A basic study by Zhang et al,in a recent issue of the World Journal of Diabetes elaborates the potential pathophysiological alterations and the therapeutic role of teneligliptin in diabetic mouse models with *** this preliminary basic study might help to improve our understanding of DbCM and offer a potential new management option for patients with the disease,the positive results from such animal models might not always translate to clinical practice as the pathobiology of DbCM in humans could be ***,such experimental studies can encourage more scientific efforts to find a better solution to treat patients with this enigmatic disease.

关键词： Diabetic cardiomyopathy Diabetic cardiomyopathy Heart failure Pathobiology Teneligliptin

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Diabetes and tuberculosis:An emerging dual threat to healthcare

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World Journal of Diabetes 2024年第7期15卷 1409-1416页

作者： Sahana shetty Joseph M Pappachan Cornelius James Fernandez Department of Endocrinology Kasturba Medical CollegeManipalManipal Academy of Higher EducationManipal 576104KarnatakaIndia Department of Endocrinology and Metabolism Lancashire Teaching Hospitals NHS TrustPreston PR29HTUnited Kingdom Faculty of Science Manchester Metropolitan UniversityManchester M156BHUnited Kingdom Faculty of Biology Medicine and HealthThe University of ManchesterManchester M139PLUnited Kingdom Department of Endocrinology&Metabolism Pilgrim HospitalUnited Lincolnshire Hospitals NHS TrustBoston PE219QSUnited Kingdom

Tuberculosis(TB)remains a huge global healthcare challenge even in the 21^(st) century though the prevalence has dropped in developed countries in recent *** mellitus(DM)is an important risk factor for the development and perpetuation of TB owing to the immune dysfunction in patients with *** coexistence of both diseases in the same individual also aggravates disease severity,complications,and chance of treatment failure because of gross immune alterations posed by DM as well as *** complex cellular and humoral immunological factors are involved in the dangerous interaction between TB and DM,some of which remain unknown even *** is highly important to identify the risk factors for TB in patients with DM,and vice versa,to ensure early diagnosis and management to prevent complications from this ominous *** their research study published in the recent issue of the World Journal of Diabetes,Shi et al elaborate on the factors associated with the development of TB in a large cohort of DM patients from *** such research output from different regions of the world is expected to improve our knowledge to fight the health devastation posed by TB in patients with diabetes.

关键词： Tuberculosis Diabetes mellitus Immune dysfunction Treatment failure Multi-drug resistant tuberculosis

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Effect of Sweptback Angle of a Delta Wing on Surface Pressure Distribution at Supersonic Mach Numbers

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Fluid Dynamics & Materials Processing 2024年第10期20卷 2353-2376页

作者： Shamitha shetty Asha Crasta Sher Afghan Khan Abdul Aabid Muneer Baig Mathematics Department Mangalore Institute of Technology and EngineeringVisvesvaraya Technological UniversityNear MoodabidreMangaluruKarnataka574225India Nitte Meenakshi Institute of Technology Visvesvaraya Technological UniversityBangalore560064India Department of Mechanical and Aerospace Engineering Faculty of EngineeringInternational Islamic University MalaysiaKuala Lumpur53100Malaysia Department of Engineering Management College of Engineering Prince Sultan UniversityP.O.Box 66833Riyadh11586Saudi Arabia

The purpose of this work is to shed light on the effect of the pivot position on the surface pressure distribution over a 3D wing in different flight *** study is intended to support the design and development of aerospace vehicles where stability analysis,performance optimization,and aircraft design are of primary *** following parameters are considered:Mach numbers(M)of 1.3,1.8,2.3,2.8,3.3,and 3.8,angle of incidence(θ)in the range from 5°to 25°,pivot position from h=0.2 to *** results of the CFD numerical simulations match available analytical data,thereby providing evidence for the reliability of the used *** findings provide valuable insights into the relationship between the surface pressure distribution,the Mach number and the angle of incidence.

关键词： Mach number angles of incidence stability analysis performance optimization

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PACK-CXL *** therapy for bacterial,fungal,and mixed infectious keratitis:a prospective randomized phase 3 trial

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Eye and Vision 2024年第1期10卷 10-20页

作者： Farhad Hafezi Mohammed Hosny Rohit shetty Boris Knyazer Shihao Chen Qinmei Wang Hassan Hashemi Emilio A.Torres‑Netto 无 Center for Applied Biotechnology and Molecular Medicine(CABMM) University of ZurichZurichSwitzerland ELZA Institute DietikonSwitzerland. Faculty of Medicine University of GenevaGenevaSwitzerland Department of Ophthalmology Medical University of WenzhouWenzhouChina USC Roski Eye Institute University of Southern California Los AngelesLos AngelesUSA Department of Ophthalmology University of CairoCairoEgypt Narayana Nethralaya Eye Hospital and the Postgraduate Institute of Ophthal‑mology BangaloreIndia Department of Ophthalmology Soroka University Medical CenterBen-Gurion University of the NegevBeershebaIsrael Noor Ophthalmology Research Center Noor Eye HospitalTehranIran University Hospital Zurich ZurichSwitzerland. the PACK-CXL Working Group

Background:Infectious keratitis is a major cause of global *** tested whether standalone photoactivated chromophore corneal cross-linking(PACK-CXL)may be an efective frst-line treatment in early to moderate infectious keratitis,compared with standard antimicrobial ***:This is a randomized,controlled,multinational phase 3 clinical *** in fve centers in Egypt,India,Iran,Israel,and China,aged≥18 years,with infectious keratitis of presumed bacterial,fungal,or mixed origin,were randomly assigned(1:1)to PACK-CXL,or antimicrobial *** measures included healing,defned as time to re-epithelialization of the corneal epithelial defect in the absence of infammatory activity in the anterior chamber and clearance of stromal *** success was defned as the complete resolution of signs of ***:Between July 21,2016,and March 4,2020,participants were randomly assigned to receive PACK-CXL(n=18)or antimicrobial therapy per American Academy of Ophthalmology(AAO)guidelines(n=21).No participants were lost to *** eyes were excluded from the epithelialization time analysis due to treatment failure:two in the antimicrobial therapy group,and two in the PACK-CXL *** rates were 88.9%(16/18 patients)in the PACK-CXL group and 90.5%(19/21 patients)in the medication *** was no signifcant diference in time to complete corneal re-epithelialization(P=0.828)between both treatment ***:PACK-CXL may be an alternative to antimicrobial drugs for frst-line and standalone treatment of early to moderate infectious keratitis of bacterial or fungal origin.

关键词： Photoactivated chromophore Corneal cross-linking Infectious keratitis Corneal melting PACK-CXL

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Liver surface depressions in the presence of diaphragmatic muscular bands on trans-illumination

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World Journal of Experimental Medicine 2024年第2期14卷 5-10页

作者： Shamir O Cawich Michael T Gardner Ramanand shetty Jean Pierre Louboutin Zenica Dabichan Shaneeta Johnson Department of Surgery University of the West IndiesSt AugustineTrinidad and Tobago Section of Anatomy Department of Basic Medical SciencesUniversity of the West IndiesKingston KIN7Jamaica Department of Surgery Morehouse School of MedicineAtlantaGA 30310United States

Traditional descriptions of liver anatomy refer to a smooth,convex surface contacting the *** depressions are recognized anatomic *** are many theories to explain the cause of the *** discuss the theory that these are... 详细信息

关键词： Liver Anatomy Depressions Fissure Groove Sulcus Variant

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Making pillar[6]arenes to lean: an art of tuning a supramolecular host

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Science China Chemistry 2019年第3期62卷 289-290页

作者： Dinesh shetty Ali Trabolsi Science Division New York University Abu Dhabi (NYUAD)

Symmetry and pattern are valuable forms of beauty that can be cherished on both the macroscopic and molecular levels. Scientists have always appreciated the intimate connections between symmetry and molecular structur... 详细信息

关键词： Symmetry Scientists symmetrical

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Temporal cues and the effect of their enhancement on speech perception in older adults——A scoping review

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Journal of Otology 2016年第3期11卷 95-101页

作者： Hemanth Narayan shetty All India Institute of Speech and Hearing

Temporal envelope is a low frequency amplitude modulation conveying segmental and suprasegmental information during speech ***,we seldom find ourselves in completely quiet listening environments and noise,commonly found in the surrounding environment,obscures both the fine structure cues and partly the temporal envelope cues in *** temporal content of speech emanating from noise is often enough to convey required information in normal hearing ***,the case is different in older adults(with and without hearing loss) who lack such capabilities due to the impairment in temporal *** calls attention of a researcher to delineate the importance of temporal enhancement of speech in improving speech *** are many temporal envelope strategies available in the literature,but each one has its own *** envelope enhancement by a deep band modulation(DBM) is found to be beneficial for those individuals who have had a temporal processing *** reason could be attributed to the 15 dB enhancement in the temporal envelope bandwidth between 3 and 30 Hz,extracted from each channel,which significantly increases the modulation depth such that masking of a consonant by a vowel is ***,output of deep band modulated speech is rescaled such that its duration increases and it provides relatively easy access to the word of the ***,in the near future,with more experiments related to DBM algorithm,it can be utilized in the rehabilitative devices to lessen the impact of the temporal processing impairment.

关键词： Temporal Envelope Modulation Older adults

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A simple single-step approach towards synthesis of nanofluids containing cuboctahedral cuprous oxide particles using glucose reduction

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Frontiers of Materials Science 2018年第1期12卷 74-82页

作者： U. Sandhya SHENOY A. Nityananda shetty Department of Chemistry National Institute of Technology Karnataka Surathkal Mangalore 575025 Karnataka India Department of Chemistry College of Engineering and Technology Srinivas University Mangalore 574146 India

Enhancement of thermal properties of conventional heat transfer fluids has become one of the important technical challenges. Since nanofluids offer a promising help in this regard, development of simpler and hassle free routes for their synthesis is of utmost importance. Synthesis of nanofluids using a hassle free route with greener chemicals has been reported. The single-step chemical approach reported here overcomes the drawbacks of the two-step procedures in the synthesis of nanofluids. The resulting Newtonian nanofluids prepared contained cuboctahedral particles of cuprous oxide and exhibited a thermal conductivity of 2.852 W- m-1. K-1. Polyvinylpyrro- lidone （PVP） used during the synthesis acted as a stabilizing agent rendering the nanofluid a stability of 9 weeks.

关键词： cuprous oxide nanofluids thermal conductivity viscosity

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