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Endoscopic resolution and recurrence of gastric antral vascular ectasia after serial treatment with argon plasma coagulation

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World Journal of Gastrointestinal Endoscopy 2017年第6期9卷 263-266页

作者： shashank garg Bilal Aslam Nicholas Nickl Division of Digestive Diseases and Nutrition Department of MedicineUniversity of Kentucky Department of Medicine University of Kentucky

AIM To evaluate long-term endoscopic resolution and recurrence rate of gastric antral vascular ectasia(GAVE) after argon plasma coagulation(APC) *** This was an IRB-approved retrospective single center study that included patients endoscopically treated for GAVE between 1/1/2008 to 12/31/2014. The primary and secondary end points of the study were rate of endoscopic resolution of GAVE after APC treatment and recurrence rate of GAVE after endoscopic resolution, respectively. Endoscopic resolution of GAVE was defined as no endoscopic evidence of GAVE after treatment with APC. Recurrence of GAVE was defined as endoscopic reappearance of GAVE after prior *** Twenty patients met the study criteria. Median age(range) of the patients was 59.5 years(42-74 years). GAVE was associated with underlying cirrhosis in 16(80%) patients. Indications for initial esophagogastroduodenoscopy(EGD) included hematemesis and/or melena(9/20, 45%), iron deficiency anemia(6/20, 30%), screening or surveillance of varices(4/20, 20%), and occult gastrointestinal bleeding(1/20, 5%). The patients were treated with a total of 55 APC sessions(range 1-7 sessions). Successful endoscopic resolution of GAVE wasachieved in 8 out of 20 patients(40%). There was no correlation between number of treatment sessions and GAVE treatment success(P = NS). Recurrence of GAVE was noted on a subsequent EGD in 2 out of 8 patients(25%) with prior endoscopic resolution of GAVE. Median follow-up period for the study population was 627 d(range 63-1953 d).CONCLUSION Endoscopic resolution rate of GAVE was low(40%) with a 25% recurrence rate after treatment with APC. These rates suggest that APC treatment of GAVE may not be optimal in many circumstances.

关键词：胃的 antral 脉管的 ectasia 氩血浆凝结

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一例罕见的感染性结肠炎

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Gastroenterology Report 2016年第4期4卷 328-330,I0003页

作者： Aditya Kalakonda shashank garg Suraj Tandon Rakesh Vinayak Sudhir Dutta State University of New York(SUNY)Upstate Medical University SyracuseNYUSA Department of Gastroenterology Sinai Hospital of BaltimoreBaltimoreMDUSA

Methicillin-resistant Staphylococcus aureus(MRSA)is responsible for numerous infectious *** tract involvement is rather rare and only a handful of cases of MRSA colitis have been reported in North *** present a case of MRSA colitis in an adult without apparent risk *** computed tomography(CT)showed thickening of the sigmoid colon,indicative of colitis,and empiric therapy with ciprofloxacin and metronidazole was *** work-up for infection-including blood and stool cultures,and stool Clostridium difficile toxin assay-was *** patient’s clinical status improved but his diarrhea did not *** of stool culture demonstrated luxuriant growth of MRSA sensitive to *** vancomycin was administered and the patient’s symptoms promptly ceased.

关键词： methicillin-resistant Staphylococcus aureus infectious colitis stool culture

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Removal of chromium from water effluent by adsorption onto <i>Vetiveria zizanioides</i>and <i>Anabaena</i>species

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Natural Science 2013年第3期5卷 341-348页

作者： Manoj Kumar Abhradip Pal Joginder Singh shashank garg Madhu Bala Ashish Vyas Yogender Pal Khasa Umesh C. Pachouri Aarupadai Veedu Institute of Technology Tamilnadu India Department of Biotechnology and Biosciences Lovely Professional University Phagwara India Department of Microbiology South Campus University of Delhi New Delhi-110021 India Institute of Nuclear Medicine & Allied Sciences Defence Research and Development Organisation New Delhi India

Bioadsorption phenomenon is more or less like a chemical reaction and several parameters are bound to affect the process. The pH, amount of adsorbent and agitation time influence the biosorptive potentiality. Hence, the present study on adsorption of Cr(VI) by activated Vetivera roots and Blue green algae Anabaena supports that it is an effective low cost adsorbent for the removal of Cr(VI) from plating effluent. Langmuir and Freundlich adsorption isotherm correlate the equilibrium adsorption data. In batch experiments both Vetiveria and Anabaena species were found to be cost effective biosorbent for the efficient removal of Cr(VI) from the effluent and comparatively Anabaena species was found to adsorb maximum Cr(VI) (88.86%) at a low contact time of 60 min. The data obtained from the experiments and modeling would prove useful in designing and fabricating an efficient treatment plant for Cr(VI) rich effluent.

关键词： Bioadsorption Vetiveria Anabaena Adsorption Isotherm Chromium

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为什么针对轻度急性胆源性胰腺炎所实施胆囊切除术越来越少?基于美国再入院数据库(2010-2014)对胆囊切除术的趋势评估及预测因素分析

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Gastroenterology Report 2019年第5期7卷 331-337,I0002页

作者： Sushil Kumar garg Fateh Bazerbachi shashank Sarvepalli Shounak Majumder Shanthi Swaroop Vege Division of Gastroenterology and Hepatology Mayo ClinicRochesterMNUSA Division of Gastroenterology Massachusetts General HospitalBostonMAUSA Department of Hospital Medicine Cleveland ClinicClevelandOHUSA

背景:当前指南推荐对因轻度急性胆源性胰腺炎(MABP)入院患者行胆囊切除术,其治疗效果更佳。本研究旨在评估在美国因MABP入院的患者施行胆囊切除术的全国趋势,并分析施行胆囊切除术及30天再入院的影响因素。方法:通过美国国家再入院数据... 详细信息

背景:当前指南推荐对因轻度急性胆源性胰腺炎(MABP)入院患者行胆囊切除术,其治疗效果更佳。本研究旨在评估在美国因MABP入院的患者施行胆囊切除术的全国趋势,并分析施行胆囊切除术及30天再入院的影响因素。方法:通过美国国家再入院数据库的诊断代码,收集2010-2014年间的MABP入院病例。比较不同临床特征病例的胆囊切除率。采用多因素模型分析施行胆囊切除术及30天再入院的影响因素。结果:从数据库中筛选出255,695例MABP住院病例,其30天再入院率为12.6%。有43.8%的病例接受了胆囊切除术,25.0%行经内镜逆行性胆胰管造影(ERCP)加括约肌切开术。研究期间,两种术式都呈现了一个下降趋势(P<0.001)。多因素分析显示,行ERCP加括约肌切开术或胆囊切除术的病例,其30天再入院率均显著下降,OR值(95%CI)分别为0.78(0.74-0.84)和0.37(0.35-0.39)。结论:对于MABP患者,在首次入院时行胆囊切除术或ERCP加乳头切开术均可降低30天再入院风险。尽管获益显著,而且指南也推荐在MABP首次入院期间行胆囊切除术,但胆囊切除率在全国范围内却呈现了一个下降的趋势。有必要进一步探究临床实践与指南所存在的这种差异的深层原因。

关键词：括约肌切开术急性胆源性胰腺炎胆囊切除再入院入院患者多因素模型住院病例诊断代码

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