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Combined automated screening for age-related macular degeneration and diabetic retinopathy in primary care settings

Annals of Eye Science 2021年第2期6卷 3-10页

作者： alauddin Bhuiyan Arun Govindaiah sharmina alauddin Oscar Otero-Marquez RTheodore Smith Research&Development Department iHealthScreen Inc.Richmond HillUSA Department of Ophthalmology Icahn School of Medicine at Mount SinaiNew YorkUSA

Background:Age-related macular degeneration(AMD)and diabetic retinopathy(DR)are among the leading causes of blindness in the United States and other developed *** detection is the key to prevention and effective *** have built an artificial intelligence-based screening system which utilizes a cloud-based platform for combined large scale screening through primary care settings for early diagnosis of these ***:iHealthScreen Inc.,an independent medical software company,has developed automated AMD and DR screening systems utilizing a telemedicine platform based on deep machine learning *** both diseases,we prospectively imaged both eyes of 340 unselected non-dilated subjects over 50 years of *** DR specifically,152 diabetic patients at New York Eye and Ear faculty retina practices,ophthalmic and primary care clinics in New York city with color fundus *** the initial review of the images,308 images with other confounding conditions like high myopia and vascular occlusion,and poor quality were excluded,leaving 676 eligible images for AMD and DR *** ophthalmologists evaluated each of the images,and after adjudication,the patients were determined referrable or non-referable for AMD *** AMD,172 were labeled referable(intermediate or late),and 504 were non-referable(no or early).Concurrently,regarding DR,33 were referable(moderate or worse),and 643 were non-referable(none or mild).All images were uploaded to iHealthScreen’s telemedicine platform and analyzed by the automated systems for both *** system performances are tested on per eye basis with sensitivity,specificity,accuracy,and kappa scores with respect to the professional ***:In identifying referable DR,the system achieved a sensitivity of 97.0%and a specificity of 96.3%,and a kappa score of 0.70 on this prospective *** AMD,the sensitivity was 86.6%,the specificity of 92.1%,and a kappa score of ***

关键词： Diabetic retinopathy age-related macular degeneration primary care

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