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Flexible sensors with zero Poisson's ratio

National Science Review 2024年第5期11卷 153-169页

作者： Xin Huang Tianzhao Bu Qingyang Zheng shaoyu liu Yangyang Li Han Fang Yuqi Qiu Bin Xie Zhouping Yin Hao Wu Department of Mechanical Engineering Flexible Electronics Research Center State Key Laboratory of Intelligent Manufacturing Equipment and Technology School of Mechanical Science and EngineeringHuazhong University of Science and Technology Department of Electronic Science and Technology School of Integrated CircuitsHuazhong University of Science and Technology

Flexible sensors have been developed for the perception of various stimuli. However, complex deformation,usually resulting from forces or strains from multi-axes, can be challenging to measure due to the lack of independent perception of multiaxial stimuli. Herein, flexible sensors based on the metamaterial membrane with zero Poisson's ratio(ZPR) are proposed to achieve independent detection of biaxial stimuli. By deliberately designing the geometric dimensions and arrangement parameters of elements, the Poisson's ratio of an elastomer membrane can be modulated from negative to positive, and the ZPR membrane can maintain a constant transverse dimension under longitudinal stimuli. Due to the accurate monitoring of grasping force by ZPR sensors that are insensitive to curvatures of contact surfaces, rigid robotic manipulators can be guided to safely grasp deformable objects. Meanwhile, the ZPR sensor can also precisely distinguish different states of manipulators. When ZPR sensors are attached to a thermal-actuation soft robot, they can accurately detect the moving distance and direction. This work presents a new strategy for independent biaxial stimuli perception through the design of mechanical metamaterials, and may inspire the future development of advanced flexible sensors for healthcare, human–machine interfaces and robotic tactile sensing.

关键词： zero Poisson's ratio metamaterials independent perception of multiaxial stimuli flexible sensor

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基于高分二号和面向对象方法的多分类器露天矿产越界开采面识别研究

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中国矿业 2024年第9期33卷 94-100页

作者：刘少宇刘丽宋永飞黄川宁夏回族自治区国土资源调查监测院宁夏银川750002 北方民族大学宁夏银川750030

矿产资源开发与利用对内陆经济欠发达省份具有十分重要的经济支撑作用,合理开发利用矿产资源是坚持可持续发展的关键之道。宁夏回族自治区矿产资源分布广泛,但以越界开采为代表的违法开采行为制约着当地经济的发展。传统的巡查上报和群... 详细信息

矿产资源开发与利用对内陆经济欠发达省份具有十分重要的经济支撑作用,合理开发利用矿产资源是坚持可持续发展的关键之道。宁夏回族自治区矿产资源分布广泛,但以越界开采为代表的违法开采行为制约着当地经济的发展。传统的巡查上报和群众举报方式使得大范围越界开采信息获取困难,而遥感数据因其广泛性和实时性被认为是监测越界开采行为的有效监管方式。本文以相关数据和高分二号影像为基础,采用面向对象方法对影像进行分割,提取地块的成像光谱和空间纹理统计特征,利用分类与回归树、随机森林和支持向量机等机器学习的分类算法,对露天矿产的越界开采面进行识别。统计结果显示,三类分类器的识别总精度均在60%以上,其中,随机森林分类器的识别效果最优,可达75%;验证结果显示,越界开采识别均存在超量分类的情况,在实际应用中应结合矿业权数据对目标区域进行进一步筛选。本文利用遥感卫星影像对越界开采面进行识别研究,极大提高了矿山执法的工作效率,推动矿产资源可持续开发利用和矿山环境保护工作的开展。

关键词：越界开采遥感识别机器学习分类算法矿产研究

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论数字时代个人信息保护的风险规制路径

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西南政法大学学报 2024年第4期26卷 142-158页

作者：刘绍宇浙江大学光华法学院杭州310000

个人信息保护制度的建构和学理讨论一直以来存在风险规制和绝对权利这两种路径。在风险规制路径下,个人信息保护被视为政府基于国家保护义务,治理数据处理对人身权、财产权和人格权等基本权所造成风险的规制活动,个人信息本身并不是被... 详细信息

个人信息保护制度的建构和学理讨论一直以来存在风险规制和绝对权利这两种路径。在风险规制路径下,个人信息保护被视为政府基于国家保护义务,治理数据处理对人身权、财产权和人格权等基本权所造成风险的规制活动,个人信息本身并不是被保护的对象。在绝对权利路径下,个人信息被建构为民法上的人格权或财产权,其本身具有被保护的价值。但这两种路径并非对立关系,与传统风险规制相比,个人信息保护的风险规制具有鲜明的特色,其对象是抽象权利,而不是物理损害。其同时包含基于风险的路径和基于权利的路径,一方面保证了规制能够量体裁衣,另一方面也维持了规制的最低标准,在风险与安全之间取得平衡。在数字时代,个人信息保护的风险规制路径能够更好地适应数字技术的创新。基于风险规制原理,有必要确立个人信息风险预防原则,对个人信息保护原则和权利予以风险化调适,建立个人信息保护独立规制机构,引入风险交流机制,改进个人信息风险评估。

关键词：个人信息保护风险规制预防原则人工智能

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新时代中国特色高校心理育人体系的构建

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南京中医药大学学报（社会科学版） 2024年第3期25卷 206-210页

作者：刘少渝福建中医药大学学生工作部福建福州350122

立足新时代我国高校心理育人工作面临的新形势,分析了高校心理育人工作存在的问题,指出照搬西方学术体系,忽视中西方文化差异,重个体轻群体以及师资队伍建设不足等因素,制约了我国高校心理育人工作的有效开展。因此,提出以自信自立为原... 详细信息

立足新时代我国高校心理育人工作面临的新形势,分析了高校心理育人工作存在的问题,指出照搬西方学术体系,忽视中西方文化差异,重个体轻群体以及师资队伍建设不足等因素,制约了我国高校心理育人工作的有效开展。因此,提出以自信自立为原则,培育时代新人为使命,中国特色社会主义文化为根基的高校心理育人理论体系;聚焦“三全育人”教育理念,强化师资队伍建设,突出中医心理特色,充分运用数字技术的高校心理育人的实践路径,从而构建中国特色高校心理育人体系。

关键词：心理育人体系高等院校中国特色自信自立中国特色社会主义文化

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联合深度学习与面向对象分析的卫宁北山露天矿山采场信息提取

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测绘通报 2024年第2期 51-57页

作者：刘丽李士垚王润刘少宇宋永飞牛瑞卿宁夏回族自治区国土资源调查监测院宁夏银川750002 中国地质调查局武汉地质调查中心(中南地质科技创新中心) 湖北武汉430205 湖北省地质环境总站湖北武汉430034 资源与生态环境地质湖北省重点实验室湖北武汉430034 中国地质大学地球物理与空间信息学院湖北武汉430074

卫宁北山地区是宁夏开展矿山生态环境恢复治理工作的关键节点区域。快速准确地获取区域内采场空间信息,监测矿山生态修复工程建设进展,已成为自治区矿政管理的重要工作之一。本文以卫宁北山地区为研究区,提出了一种联合深度学习与面向... 详细信息

卫宁北山地区是宁夏开展矿山生态环境恢复治理工作的关键节点区域。快速准确地获取区域内采场空间信息,监测矿山生态修复工程建设进展,已成为自治区矿政管理的重要工作之一。本文以卫宁北山地区为研究区,提出了一种联合深度学习与面向对象分析的国产高分辨率遥感卫星影像露天矿山采场信息提取方法。该方法首先采用支持小样本学习的U-Net模型进行露天采场的初步识别;然后结合面向对象分析与空间分析方法实现露天采场边界的精细化提取。经验证,该方法识别露天采场空间位置的精度为0.71,平均空间范围的提取精度为0.78。在此基础上,对卫宁北山地区露天矿山在2019—2021年的恢复治理情况开展识别与分析,识别出的125处露天矿山采场中有43.2%已开展生态修复工程,含44处采坑填埋与覆土整平、6处重新开发利用及4处人工复绿。结果表明,该方法在无须进行特征工程的前提下能够较为快速地对露天采场空间信息进行精细化提取,可为宁夏矿山遥感监测提供技术参考。

关键词：卫宁北山露天矿山采场深度学习面向对象遥感监测

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Monitoring the delicate operations of surgical robots via ultra-sensitive ionic electronic skin

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National Science Review 2022年第12期9卷 163-176页

作者： Danyang Wei Jiajie Guo Yuqi Qiu shaoyu liu Jiangyan Mao Yutian liu Zhenbing Chen Hao Wu Zhouping Yin State Key Laboratory of Digital Manufacturing Equipment and Technology School of Mechanical Science and EngineeringHuazhong University of Science and Technology Department of Hand Surgery Union Hospital Tongji Medical CollegeHuazhong University of Science and Technology

The arrival of surgical robots in high-end medical equipment is a landmark,and the realization of tactile sensation a major challenge in this important cutting-edge research *** to address this issue,we present ultra-sensitive ionic electronic skin in the form of flexible capacitive pressure sensors,which incorporate multistage bionic microstructures in ion gels for the purpose of monitoring the delicate operations of surgical ***,the ionic skin exhibits an ultra-high sensitivity of 9484.3 kPa-1(<15 kPa),and the sensitivity remains higher than 235 kPa-1in the wide range of 15-155 *** device has also achieved a detection limit as low as 0.12 Pa or,equivalently,0.31 mg,fast response within 24 ms,and high robustness(loading/unloading for 5000 cycles without fatigue).The sensor facilitates the challenging task of tele-operated robotic threading,which exceeds the human tactile perception limit when threading a *** have also confirmed that ionic skin can be used in robot-assisted invasive surgery,such as incision/resection of tissues and suturing of wounds,providing tactile information to surgeons to improve operation success *** flexible ionic skin is capable of conforming to the various shapes of robotic manipulators,thus has great promise for applications in robotic dexterous manipulation,prosthetics and human-machine interfaces.

关键词： surgical robots delicate operations ultra-sensitive ionic electronic skin tactile sensing

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Biodegradation pathway and mechanism of tri (2-chloropropyl) phosphate by Providencia rettgeri

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Journal of Environmental Sciences 2024年第10期144卷 26-34页

作者： Jinming Ye shaoyu Tang Rongliang Qiu Shuona Chen Huiling liu College of Natural Resources and Environment of South China Agricultural University Guangzhou 510642China Guangdong Provincial Key Laboratory of Agricultural&Rural Pollution Abatement and Environmental Safety Guangzhou 510642China Research Center for Eco-Environmental Engineering Dongguan University of TechnologyDongguan 523808China

Tri(2-chloropropyl)phosphate(TCPP)was an emerging contaminant of global concern because of its frequent occurrence,potential toxic effects,and persistence in the *** degradation might be an efficient and safe removal method,but limited information was *** this study,Providencia rettgeri was isolated from contaminated sediment and showed it could use TCPP as unique phosphorus source to promote growth,and decompose 34.7%of TCPP(1 mg/L)within 5 *** microbial inoculation and the initial concentration of TCPP could affect the biodegradation *** study results indicated that TCPP decomposition by Providencia rettgeri was mainly via phosphoester bond hydrolysis,evidenced by the production of bis(2-chloropropyl)phosphate(C6H13Cl2PO4)and mono-chloropropyl phosphate(C3H8ClPO4).Both intracellular and extracellular enzymes could degrade TCPP,but intracellular degradation was dominant in the later reaction stage,and the presence of Cu2+ions had a promoting *** findings developed novel insights into the potential mechanism of TCPP microbial degradation.

关键词： Chlorinated organophosphate flame retardants Microbial degradation Degradation pathway Providencia rettgeri Tri(2-chloropropyl)phosphate

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Effect of cyclic mechanical loading on immunoinflammatory microenvironment in biofabricating hydroxyapatite scaffold for bone regeneration

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Bioactive Materials 2021年第10期6卷 3097-3108页

作者： Penghui Zhang Xizhe liu Peng Guo Xianlong Li Zhongyuan He Zhen Li Martin J.Stoddart Sibylle Grad Wei Tian Dafu Chen Xuenong Zou Zhiyu Zhou shaoyu liu Innovation Platform of Regeneration and Repair of Spinal Cord and Nerve Injury Department of Orthopaedic SurgeryThe Seventh Affiliated HospitalSun Yat-sen UniversityShenzhen518107China Guangdong Provincial Key Laboratory of Orthopedics and Traumatology Orthopaedic Research Institute/Department of Spinal SurgeryThe First Affiliated Hospital of Sun Yat-sen UniversityGuangzhou510080China AO Research Institute Davos Clavadelerstrasse 8Davos7270Switzerland Laboratory of Bone Tissue Engineering Beijing Laboratory of Biomedical MaterialsBeijing Research Institute of Orthopaedics and TraumatologyBeijing JiShuiTan HospitalBeijing100035China

It has been proven that the mechanical microenvironment can impact the differentiation of mesenchymal stem cells(MSCs).However,the effect of mechanical stimuli in biofabricating hydroxyapatite scaffolds on the inflammatory response of MSCs remains *** study aimed to investigate the effect of mechanical loading on the inflammatory response of MSCs seeded on *** mechanical loading was applied to biofabricate the cell-scaffold composite for 15 min/day over 7,14,or 21 *** the predetermined time points,culture supernatant was collected for inflammatory mediator detection,and gene expression was analyzed by *** results showed that the expression of inflammatory mediators(IL1B and IL8)was downregulated(p<0.05)and the expression of ALP(p<0.01)and COL1A1(p<0.05)was upregulated under mechanical *** cell-scaffold composites biofabricated with or without mechanical loading were freeze-dried to prepare extracellular matrix-based scaffolds(ECM-based scaffolds).Murine macrophages were seeded on the ECM-based scaffolds to evaluate their *** ECM-based scaffolds that were biofabricated with mechanical loading before freeze-drying enhanced the expression of M2 polarization-related biomarkers(Arginase 1 and Mrc1,p<0.05)of macrophages in vitro and increased bone volume/total volume ratio in ***,these findings demonstrated that mechanical loading could dually modulate the inflammatory responses and osteogenic differentiation of ***,the ECM-based scaffolds that were biofabricated with mechanical loading before freeze-drying facilitated the M2 polarization of macrophages in vitro and bone regeneration in *** loading may be a promising biofabrication strategy for bone biomaterials.

关键词： Bioreactor Biofabrication Inflammatory microenvironment Bone biomaterials Macrophage polarization

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对川东基底性质、结构的探讨

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天然气工业 1989年第2期9卷 15-20页

作者：刘绍裕四川石油管理局地质调查处

本文利用川东过去的重、磁力资料,采用计算机重新处理,作出了该区剩余重力异常、剩余磁力异常及滋力垂直一次导数异常等图件,并结合地震、地质及钻井资料,对川东基底的性质、结构作了详细的解释,为深部气藏的勘探、研究提供了重要的资料。

关键词：油气勘探基底构造地质解释

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A single-cell transcriptome of mesenchymal stromal cells to fabricate bioactive hydroxyapatite materials for bone regeneration

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Bioactive Materials 2022年第3期7卷 281-298页

作者： Peng Guo Xizhe liu Penghui Zhang Zhongyuan He Zhen Li Mauro Alini RGeoff Richards Sibylle Grad Martin J.Stoddart Guangqian Zhou Xuenong Zou Danny Chan Wei Tian Dafu Chen Manman Gao Zhiyu Zhou shaoyu liu Innovation Platform of Regeneration and Repair of Spinal Cord and Nerve Injury Department of Orthopaedic SurgeryThe Seventh Affiliated Hospital of Sun Yat-sen UniversityShenzhenChina Guangdong Provincial Key Laboratory of Orthopaedics and Traumatology The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina AO Research Institute Davos DavosSwitzerland Shenzhen Key Laboratory of Anti-aging and Regenerative Medicine Department of Medical Cell Biology and GeneticsHealth Sciences CenterShenzhen UniversityShenzhenChina School of Biomedical Sciences LKS Faculty of MedicineThe University of Hong KongHong Kong SARChina Laboratory of Bone Tissue Engineering Beijing Laboratory of Biomedical MaterialsBeijing Research Institute of Orthopaedics and TraumatologyBeijing JiShuiTan HospitalBeijingChina Department of Sport Medicine Inst Translat MedThe First Affiliated Hospital of Shenzhen UniversityShenzhen Second People’s HospitalShenzhenChina

The osteogenic microenvironment of bone-repairing materials plays a key role in accelerating bone regeneration but remains incompletely defined,which significantly limits the application of such bioactive ***,the transcriptional landscapes of different osteogenic microenvironments,including three-dimensional(3D)hydroxyapatite(HA)scaffolds and osteogenic medium(OM),for mesenchymal stromal cells(MSCs)in vitro were mapped at single-cell *** findings suggested that an osteogenic process reminiscent of endochondral ossification occurred in HA scaffolds through sequential activation of osteogenic-related signaling pathways,along with inflammation and angiogenesis,but inhibition of adipogenesis and ***,we revealed the mechanism during OM-mediated osteogenesis involves the ZBTB16 and WNT signaling *** of MSCs was also *** vitro ossification of LRRC75A+MSCs was shown to have better utilization of WNT-related ossification process,and PCDH10+MSCs with superiority in hydroxyapatite-related osteogenic *** findings provided further understanding of the cellular activity modulated by OM conditions and HA scaffolds,providing new insights for the improvement of osteogenic *** atlas provides a blueprint for research on MSC heterogeneity and the osteogenic microenvironment of HA scaffolds and a database reference for the application of bioactive materials for bone regeneration.

关键词： inflammation bioactive finding

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