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Connotation analysis, source-reservoir assemblage types and development potential of unconventional hydrocarbons in China

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Petroleum Research 2016年第2期1卷 135-148页

作者： Jianzhong Li Min Zhen Xiaoming Chen Denghua Li shaoyong wang Tao Song PetroChina Research Institute of Petroleum Exploration and Development Beijing 100083China

Through analysis of the connotation of unconventional hydrocarbons,the source-reservoir assemblages of unconventional hydrocarbons are divided into three types,i.e.,source-reservoir neighboring type,source-reservoir integration type,and source-reservoir separation *** source-reservoir neighboring type resources mainly include tight oil and tight gas with the following formation conditions and characteristics:(1)efficient near-source accumulation close to high-quality source rocks with the pressure difference between source and reservoir as the dynamic force;(2)large-area tight reservoirs with certain porosity,dominated by micro-nanopores of inorganic origin;(3)distributed in depressions and slopes with large hydrocarbon-bearing area and great resource quantity,low abundance and local development of“sweet spots”;(4)weak *** source-reservoir integration type resources mainly include coalbed methane,shale gas,shale oil and oil *** formation conditions and characteristics are:(1)high abundance of organic matter,different types of organic matter and thermal evolution grades leading to formation of different resources types;(2)organic-rich sections are distributed continuously in the reservoiring space which is dominated by nanometer organic pores,interparticle pores and microfissures;(3)hydrocarbons mainly occur in free or adsorbed state,varying much with resource type;(4)the resources are self-conserved,and enriched in depressions and slopes,the conservation conditions are controlled by tectonics,temperature and pressure;(5)the production per well can be enhanced by volume fracturing,which increases the permeability of the *** source-reservoir separation type resources are more special,mainly including(1)transformed conventional resources such as oil sand and heavy oil;(2)unsteady resources formed under special conditions of temperature and pressure,among which natural gas hydrate is a *** three types of resources in Chin

关键词： Unconventional hydrocarbons connotation source-reservoir assemblage source-reservoir neighboring type source-reservoir integration type source-reservoir separation type development potential

数字化背景下美国青年学徒制:实施现状、应对策略及经验启示

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当代职业教育 2024年第1期 84-93页

作者：王少勇唐晓蕾罗文青方晓田四川外国语大学重庆400031

美国青年学徒制旨在降低青年失业率和填补企业未满足的劳动力需求,获得社会广泛支持。数字化背景下,美国青年学徒制开发了系列指导原则,形成了以职业为导向、注重公平、学分可转换、强调适应性和建立问责制等特色。同时也面临着数据收... 详细信息

美国青年学徒制旨在降低青年失业率和填补企业未满足的劳动力需求,获得社会广泛支持。数字化背景下,美国青年学徒制开发了系列指导原则,形成了以职业为导向、注重公平、学分可转换、强调适应性和建立问责制等特色。同时也面临着数据收集标准与范围不明确,各利益相关主体的角色及责任不清晰,数据收集基础设施建设不完善,数据访问和存储有待进一步优化等方面的问题。美国采取了数据收集和使用以学习者为中心、开发青年学徒制数据框架、促进雇主与行业的共同参与、把职业教育与青年学徒项目联系起来、加强青年学徒制的质量评估等应对策略。这对发展中国特色学徒制提供了经验启示:现代学徒制试点学校的课程设置要强调以学生为中心,建立学徒制信息数据平台,明确学校和企业职责,建立纵向贯通的就业和升学渠道,搭建全过程综合评价平台。

关键词：美国青年学徒制数字化职业教育现代学徒制

Accelerating column leaching trial on copper sulfide ore

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Rare Metals 2008年第1期27卷 95-100页

作者： wang Hongjiang WU Aixiang ZHOU Xun wang shaoyong ZHANG Jie Civil and Environment Engineering School University of Science and Technology Beifing Beifing 100083 China School of Resource and Safety Engineering Central South University Changsha 410083 China

The main measures to accelerate leaching sulfide ore are large spraying intensity,manual oxygen supply,temperature control,and acclimated *** indoor experiment accelerating sulfide ore leaching detected the temperature during leaching process,dissolvability of oxygen,bacterial concentration,Cu concentration and slag *** the same time,this paper also analyzed the effect of four factors,which are bacterial diversity cultivation stage,spraying intensity,air supply,and whether to control temperature,on the leaching efficiency of *** results indicate that the oxygen content of leach solution has a close relationship with temperature but it is rarely affected by air *** bacterial concentration preserves from 106 to 107 mL^-1,and temperature has a great effect on the bacterial activity under the condition of proper temperature and oxygen supply,and the lack of nutrition prevents the bacterial concentration from rising in the late *** relationships of the copper leaching efficiency to temperature,air feed,and spraying intensity are directly *** leaching efficiencies of the cultivated bacteria and acclimation bacteria are 1.2 and 1.4 times as large as that of the original bacteria.

关键词： accelerating leaching spraying intensity manual air supply temperature control bacterial cultivation

基于网络化资源共享的地铁供电系统可靠性研究

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自动化与仪器仪表 2024年第6期 140-145页

作者：闫思玲张宏熙王绍勇孙名刚赵宇坤北京市地铁运营有限公司供电分公司北京100082 北京城建设计发展集团股份有限公司北京100034 北京石油化工学院安全工程学院北京102617

地铁是城市公共交通重要组成部分之一,地铁安全的重要性不言而喻。目前,北京地铁线网各条线路均采用10 kV分散式供电与双环网式接线方式,但北京地铁存在个别10 kV外部电源迟迟不能投入的情况,导致单条线路10 kV开闭所之间相互支援能力不... 详细信息

地铁是城市公共交通重要组成部分之一,地铁安全的重要性不言而喻。目前,北京地铁线网各条线路均采用10 kV分散式供电与双环网式接线方式,但北京地铁存在个别10 kV外部电源迟迟不能投入的情况,导致单条线路10 kV开闭所之间相互支援能力不足,一旦线路出现故障,就可能会带来严重的经济和社会影响。因此,以6号线与2号线的分散式供电系统为研究实例,在不降低行车对数的情况下,从线网间支援供电角度出发,建立中压环网线网支援供电系统,基于中压环网系统的变压器容量选择、电压约束、电流约束和运行方式四个方面,以母线压降和进线电流为指标,评估不同运行工况下的地铁网络化支援供电系统的可靠性,实现供电系统网络化运行和资源共享。

关键词：支援供电供电系统网络化运行资源共享

Assessment on Tight Oil Resources in Fuyu Oil Layer in the Sanzhao Sag and Relevant Parameters

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Acta Geologica Sinica(English Edition) 2015年第A1期89卷 226-229页

作者： ZHENG Man wang Shejiao GUO Qiulin wang Rui XIE Hongbin wang shaoyong PetroChina Research Institute of Petroleum Exploration andDevelopment Beijing 100083 China Geological Brigade of No.9 Oil Production Plant PetroChina Daqing Oilfield Company Limited Daqing Heilongiiang163853 China

The oil reservoir formed by Quan3 and Quan4 tight sandstones, also called Fuyu oil layer, in the Sanzhao sag, northem Songliao Basin, contains ＂sub-source＂ tight oil, which sourced from the overlying Qingl lacustrine mudstone that acts as the caprock of the Fuyu oil layer, with the Quan3 and Quan4 tight sand bodies of fluvial- shoal water delta sedimentary system as reservoir bed, constituting a ＂upper source and lower reservoir＂ type source-reservoir-caprock assemblage. By far, about 5.38× 10^8t conventional oil in place has been proved in the Fuyu oil layer, and good exploration results have been achieved.

关键词： SANDSTONE HYDROCARBONS OIL fields PETROLEUM reserves PETROLEUM reservoirs

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基于分布式电源的微网的设计与运行

电力自动化设备 2011年第4期31卷 120-123页

作者：汪少勇广东省电力设计研究院广东广州510663

结合微网和分布式电源的特点,着重讨论了其设计、运行、优化、控制等问题。通过设计实例,指出微网的设计要遵循安全可靠、功率平衡、运行灵活的原则;分析了微网的结构和运行方式,对于并网运行模式、孤网运行模式、双模式进行了详细说明... 详细信息

结合微网和分布式电源的特点,着重讨论了其设计、运行、优化、控制等问题。通过设计实例,指出微网的设计要遵循安全可靠、功率平衡、运行灵活的原则;分析了微网的结构和运行方式,对于并网运行模式、孤网运行模式、双模式进行了详细说明,提出在不同的运行模式下微网设计的特点;对于微网和分布式电源的控制系统和优化运行提出了建议,提出了建立微网能量管理系统的大致思路;对需要注意的一些事项,如防孤岛保护、短路电流等进行了说明,提出用主动检测法和被动检测法进行防孤岛保护的实施方案。

关键词：微网分布式电源设计运行模式防孤岛保护微网能量管理系统

平均电流型Boost PFC变换器中过零畸变

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电工技术学报 2011年第2期26卷 129-133,155页

作者：王少永张方华南京航空航天大学航空电源航空科技重点实验室南京210016

有源功率因数校正变换器中,通常会使用滤波电容来吸收开关纹波和噪声。在中频(360～800Hz)应用场合,流入滤波电容的电流会变得很大。滤波电容的电流超前输入电压90°,这样功率因数就会变得很差。同时电流环在中频情况下会产生超前相位... 详细信息

有源功率因数校正变换器中,通常会使用滤波电容来吸收开关纹波和噪声。在中频(360～800Hz)应用场合,流入滤波电容的电流会变得很大。滤波电容的电流超前输入电压90°,这样功率因数就会变得很差。同时电流环在中频情况下会产生超前相位。电流环和直流滤波电容造成的超前相位致使输入电流在输入电压过零附近产生严重的畸变。通过分析输入滤波电容和电流环的影响,指出直流滤波电容是引起输入电流发生过零畸变的重要原因之一。在此基础上,采用了相位补偿的方法来补偿直流滤波电容和电流环造成的超前相位,降低了输入电流的总谐波含量,使功率因数接近为1。

关键词：有源功率因数校正直流滤波电容开关纹波过零畸变总谐波含量

辽西雷家地区沙四段中-低熟烃源岩排烃效率与致密油-页岩油勘探前景

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石油与天然气地质 2019年第4期40卷 810-821页

作者：王媛汪少勇李建忠张义杰中国石油勘探开发研究院

辽河西部凹陷雷家地区沙河街组四段在咸化闭塞湖湾环境下,发育高丰度厚层云质、方沸石质泥岩和页岩,整体处于低成熟阶段(R_o=0.3%~0.7%)。铸体薄片、扫描电镜分析表明,页岩储层广泛发育构造缝和收缩缝,碎屑矿物粒间孔发育,纳米孔主要为... 详细信息

辽河西部凹陷雷家地区沙河街组四段在咸化闭塞湖湾环境下,发育高丰度厚层云质、方沸石质泥岩和页岩,整体处于低成熟阶段(R_o=0.3%~0.7%)。铸体薄片、扫描电镜分析表明,页岩储层广泛发育构造缝和收缩缝,碎屑矿物粒间孔发育,纳米孔主要为白云石、方沸石矿物溶蚀孔,有机质纳米孔不发育。采用TOC测井定量评价方法(ΔlgR法)明确了沙四段优质烃源岩(TOC>4%)的纵横向展布特征。其中,杜家台油层优质烃源岩和高升油层优质烃源岩均集中分布在雷家-陈家洼陷地区。排烃效率实验分析结果表明,在当前热演化程度下,烃源岩排烃效率在12%~17%,总生烃量在10~35 mg/g。由于高丰度烃源岩累积厚度大,估算雷家地区沙四段致密油-页岩油总资源量达1.37×10~8 t。通过源-储组合综合分析,认为雷家地区沙四段杜家台油层为致密油-页岩油有利勘探区,高升油层为页岩油有利勘探区,由于各类岩性均具有一定的生烃潜力和储集能力,适合致密油-页岩油整体开发。

关键词：源-储组合中-低熟烃源岩排烃效率致密油-页岩油沙四段雷家地区辽西凹陷

Discovery of a potent and highly selective inhibitor of SIRT6 against pancreatic cancer metastasis in vivo

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Acta Pharmaceutica Sinica B 2024年第3期14卷 1302-1316页

作者： Xinyuan Xu Qian Zhang Xufeng wang Jing Jin Chengwei Wu Li Feng Xiuyan Yang Mingzhu Zhao Yingyi Chen shaoyong Lu Zhen Zheng Xiaobing Lan Yi wang Yan Zheng Xuefeng Lu Qiufen Zhang Jian Zhang State Key Laboratory of Medical Genomics National Research Center for Translational Medicine at ShanghaiRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Medicinal Chemistry and BioinformaticsCenter Shanghai Jiao Tong University School of MedicineShanghai 200025China Department of General Surgery Huashan HospitalCancer Metastasis InstituteFudan UniversityShanghai 200040China Institute of Immunology and the CAS Key Laboratory of Innate Immunity and Chronic Disease School of Basic Medicine and Medical CenterUniversity of Science and Technology of ChinaHefei 230026China Department of Assisted Reproduction Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China College of Pharmacy Ningxia Medical UniversityYinchuan 750004China Department of Pancreatic Surgery Shanghai General HospitalShanghai Key Laboratory of Pancreatic DiseaseInstitute of Pancreatic DiseaseShanghai Jiao Tong University School of MedicineShanghai 200080China

Pancreatic cancer,one of the most aggressive malignancies,has no effective treatment due to the lack of targets and drugs related to tumour ***6 can promote the migration of pancreatic cancer and could be a potential target for antimetastasis of pancreatic ***,highly selective and potency SIRT6 inhibitor that can be used in vivo is yet to be ***,we developed a noveSIRT6 allosteric inhibitor,compound 11e,with maximal inhibitory potency and an IC_(50) value of 0.98±0.13μmol/***,compound 11e exhibited significant selectivity against other histone deacetylases(HADC1-11 and SIRT1-3)at concentrations up to 100μmol/*** allosteric site and the molecular mechanism of inhibition were extensively elucidated by cocrystal complex structure and dynamic structural ***,we confirmed the antimetastatic function of such inhibitors in four pancreatic cancer cell lines as well as in two mouse models of pancreatic cancer liver *** our knowledge,this is the first study to reveal the in vivo effects of SIRT6 inhibitors on liver metastatic pancreatic *** not only provides a promising lead compound for subsequent inhibitor developmentargeting SIRT6 but also provides a potential approach to address the challenge of metastasis in pancreatic cancer.

关键词： SIRT6 Inhibitor Allosteric Selectivity Cocrystal Pancreatic cancer metastasis