检索结果-南通市图书馆

Exchanges between shaoxing and Japanese youths

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Voice of Friendship 2019年第1期 23-25页

作者： shaoxing Foreign Affairs Office shaoxing Foreign Affairs Office

As close neighbors separated by a strip of water,China and Japan share interlinked culture and longterm people-to-people ***-level leaders have attached great importance to youth exchanges between the two countries,which have become an important part of bilateral efforts to improve the two peoples’mutual friendly feelings and cultivate successors in the cause of friendship.

关键词： Exchanges shaoxing and Japanese youths friendly feelings

Research on Cluster Innovation System——Taking shaoxing Textile Industrial Cluster as an Example

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research on Cluster Innovation System——Taking Shaoxing Tex...

A Review on the Mullins Effect in Tough Elastomers and Gels

第十一届全国经济管理院校工业技术学研究会

作者： Pinhou HANG Department of economic and management,Zhejiang industry polytechnic college,shaoxing,China

The role of industrial clusters is very important to regional and national *** studying the innovation system of industrial clusters can develop industrial clusters,it may improve the speed and level of innovation and develop the regional and national *** paper analyzes the core components of the clusters innovation system and knowledge flow among them and taking shaoxing textile industrial cluster as an example,then give some suggestions for the improvement of the cluster innovation system.

关键词： Industrial cluster Clusters innovation system Knowledge flow

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Acta Mechanica Solida Sinica 2024年第2期37卷 181-214页

作者： Lin Zhan shaoxing Qu Rui Xiao MOE Key Lab of Disaster Forecast and Control in Engineering College of Mechanics and Construction EngineeringJinan UniversityGuangzhou510632China State Key Laboratory of Fluid Power and Mechatronic System Key Laboratory of Soft Machines and Smart Devices of Zhejiang ProvinceDepartment of Engineering MechanicsZhejiang UniversityHangzhou310027China

Tough elastomers and gels have garnered broad research interest due to their wide-ranging potential ***,during the loading and unloading cycles,a clear stress softening behavior can be observed in many material systems,which is also named as the Mullins *** this work,we aim to provide a complete review of the Mullins effect in soft yet tough materials,specifically focusing on nanocomposite gels,double-network hydrogels,and multi-network *** first revisit the experimental observations for these soft *** then discuss the recent developments of constitutive models,emphasizing novel developments in the damage mechanisms or network *** phenomenological models will also be briefly *** attention is then placed on the anisotropic and multiaxial modeling *** is demonstrated that most of the existing models fail to accurately predict the multiaxial data,posing a significant challenge for developing future anisotropic models tailored for tough gels and elastomers.

关键词： Mullins effect Double-network hydrogels Nanocomposite gels Multi-network elastomers Anisotropic damage model Multiaxial model

Integrative bioinformatics and in vitro exploration of EVI2A expression:unraveling its immunological and prognostic implications in kidney renal clear cell carcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oncology Research 2024年第11期32卷 1733-1746页

作者： RONG LIU SHENG LI SITU XIONG FUCUN ZHENG XIANGPENG ZHAN JIN ZENG BIN FU SONGHUI XU shaoxing ZHU RU CHEN Department of Urology Fujian Medical University Union HospitalFuzhou350000China Department of Urology The First Affiliated Hospital of Nanchang UniversityNanchang350000China

EVI2A has emerged as a significant biomarker in various diseases;however,its biological role and mechanism in kidney renal clear cell carcinoma(KIRC)remains *** used TCGA and GEO databases to analyze EVI2A gene expression comprehensively and performed pan-cancer *** relevance was evaluated through Kaplan-Meier analysis and ROC *** gene’s immune relevance was explored through analyses of the tumor microenvironment(TME),Tumor Immune Single-cell Hub(TISCH),immune checkpoints,and immunotherapy *** results indicate that EVI2A expression is upregulated in KIRC,showing correlations with tumor grade and T/N/M ***2A demonstrates high diagnostic accuracy(AUC=0.906)and predicts poor overall and progression-free survival in KIRC ***,EVI2A expression exhibits significant associations with immunity,including TME scores and specific immune cell types such as Tfh cells,CD4 memory T cells,and CD8+T *** EVI2A expression suggests increased sensitivity to PD-1/CTLA-4 and tyrosine kinase *** vitro assays confirmed the impact of EVI2A on KIRC behavior,with its knockdown resulting in reduced cell proliferation and *** conclusion,our comprehensive analysis identifies EVI2A as a promising biomarker and a novel therapeutic target for intervening in *** findings hold significant implications for further research and potential clinical applications.

关键词： EVI2A Kidney Renal Clear Cell Carcinoma(KIRC) Prognosis Immunological analysis

Novel Role of Calcium-Sensitive Receptors in Chronic Hypoxia-Induced Proliferation of Pulmonary Vein Smooth Muscle Cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Clinical and Nursing Research 2024年第7期8卷 349-355页

作者： shaoxing Li Jurong Zhang Zhuandi Lin Zhiming Xiang Gongyong Peng The Affiliated Panyu Central Hospital of Guangzhou Medical University Guangzhou 510120Guangdong ProvinceChina The First Affiliated Hospital of Guangzhou Medical University Guangzhou 510120Guangdong ProvinceChina

Objective:Vascular remodeling due to chronic hypoxia(CH)occurs not only in the pulmonary arteries but also in the pulmonary *** vascular remodeling arises from the proliferation of pulmonary vascular ***,the mechanism by which CH induces the proliferation of pulmonary vein smooth muscle cells(PVSMCs)is *** study aimed to investigate the mechanism by which CH affects the proliferation of ***:PVSMCs were isolated from rat distal pulmonary veins and exposed to CH(4%O2,60h),and the expression of the calcium-sensitive receptor(CaSR)was detected by Western blotting and *** assay was used to detect the proliferation viability of the cells,and the changes in the intracellular calcium concentration were detected by laser confocal scanning ***:CaSR expression was present in rat distal PVSMCs,and CaSR protein expression was upregulated under *** positive regulator spermine not only enhanced CH-induced CaSR upregulation but also enhanced CH-induced increase in cell viability and calcium ion *** negative CaSR regulator NPS2143 not only attenuated CH-induced CaSR upregulation but also inhibited CH-induced cell viability and calcium ion ***:CaSR-mediated hyperproliferation is a novel pathogenic mechanism for the development of proliferation in distal PVSMCs under CH conditions.

关键词： Hypoxia Calcium-sensitive receptor(CaSR) Pulmonary hypertension Cell proliferation Calcium ions

Long-term in vivo chimeric cells tracking in non-human primate

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Protein & Cell 2024年第3期15卷 207-222页

作者： Junmo Wu Yu Kang Xiang Luo shaoxing Dai Yuxi Shi Zhuoyao Li Zengli Tang Zhenzhen Chen Ran Zhu Pengpeng Yang Zifan Li Hong Wang Xinglong Chen Ziyi Zhao Weizhi ji Yuyu Niu State Key Laboratory of Primate Biomedical Research Institute of Primate Translational MedicineKunming University of Science and TechnologyKunming 650500China Yunnan Key Laboratory of Primate Biomedical Research Kunming 650500China Faculty of Life Science and Technology Kunming University of Science and TechnologyKunming 650500China

Non-human primates(NHPs)are increasingly used in preclinical trials to test the safety and efficacy of biotech-nology ***,given the ethical issues and costs associated with this model,it would be highly advantageous to use NHP cellular models in clinical ***,developing and maintaining the naive state of primate pluripotent stem cells(PSCs)remains difficult as does in vivo detection of PSCs,thus limiting biotech-nology application in the cynomolgus ***,we report a chemically defined,xeno-free culture system for culturing and deriving monkey PSCs in *** cells display global gene expression and genome-wide hypometh-ylation patterns distinct from monkey-primed *** also found expression of signaling pathways components that may increase the potential for chimera *** for biomedical applications,we were also able to integrate bioluminescent reporter genes into monkey PsCs and track them in chimeric embryos in vivo and in *** engineered cells retained embryonic and extra-embryonic developmental ***,we generated a chimeric monkey carrying bioluminescent cells,which were able to track chimeric cells for more than 2 years in living *** study could have broad utility in primate stem cell engineering and in utilizing chimeric monkey models forclinical studies.

关键词： pluripotent stem cells bioluminescence imaging non-human primates

维普期刊数据库

时空循环逻辑下城乡关系及融合发展的政治经济解析

在线全文

学校读者我要写书评

暂无评论

城市发展研究 2024年第3期31卷 32-38页

作者：王金岩李少星山东大学土建与水利学院山东大学山东发展研究院山东大学经济研究院

城乡融合作为我国破解发展不平衡不充分问题、推动国内经济社会高水平循环的重要战略，不仅是新时期中国式现代化的重大政策实践，也是马克思主义政治经济理论的创新性探索。通过回溯“扩大再生产所需要追加货币的由来”的资本循环过程... 详细信息

城乡融合作为我国破解发展不平衡不充分问题、推动国内经济社会高水平循环的重要战略，不仅是新时期中国式现代化的重大政策实践，也是马克思主义政治经济理论的创新性探索。通过回溯“扩大再生产所需要追加货币的由来”的资本循环过程，阐明了城乡相互作用的时空机理，揭示了城乡关系演变的政治经济逻辑。面向新时代，中国的城乡融合进程将在资本集聚扩散与要素再分配等内在动力作用下，围绕社会分工、产品交换、地域分布，不断展现全新的有机分布形式，并通过供需关系创新、国土空间重构、体制制度优化、共享发展推动等政策举措而实现高质量发展。

关键词：资本循环城乡关系扩大再生产时空循环逻辑城乡融合

智能软材料多场耦合本构理论及其在软体机器中的应用

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中国科学：物理学、力学、天文学 2024年第6期54卷 2-14页

作者：肖锐钱劲曲绍兴浣江实验室诸暨311800 浙江大学工程力学系浙江省软体机器人与智能器件研究重点实验室杭州310027

智能软材料能在外场作用下产生激励效应,且其智能响应行为与大变形深度耦合,这对建立其力学本构理论提出了重要挑战.本文以形状记忆聚合物、液晶弹性体、介电弹性体、磁敏弹性体、智能水凝胶为代表性智能软材料,介绍了上述材料的发展概... 详细信息

智能软材料能在外场作用下产生激励效应,且其智能响应行为与大变形深度耦合,这对建立其力学本构理论提出了重要挑战.本文以形状记忆聚合物、液晶弹性体、介电弹性体、磁敏弹性体、智能水凝胶为代表性智能软材料,介绍了上述材料的发展概况以及在相关多场耦合本构理论领域的进展.智能软材料在软体机器人领域也有着广泛的应用前景,因此,本文也将探讨基于软材料多场耦合理论模型来设计软体机器人的现状以及不足之处,以期为后续该领域的发展提供借鉴.

关键词：软材料软体机器人多场耦合

维普期刊数据库

在线全文

学校读者我要写书评

暂无评论

中国式现代化进程中的政党治理现代化

中国特色社会主义研究 2024年第1期 16-25,F0002页

作者：王韶兴任丹丹山东大学马克思主义学院山东大学世界政党研究中心

现代国家成长内蕴政党治理现代化,政党治理现代化引领现代国家成长,是政党政治时代人类文明发展的显著特征和基本逻辑。由政党民主体系和民主能力、政党法治体系和法治能力,以及政党领导和政党执政、政党权威和政党权力等价值范畴构成... 详细信息

现代国家成长内蕴政党治理现代化,政党治理现代化引领现代国家成长,是政党政治时代人类文明发展的显著特征和基本逻辑。由政党民主体系和民主能力、政党法治体系和法治能力,以及政党领导和政党执政、政党权威和政党权力等价值范畴构成的马克思主义政党自身治理现代化的价值基点,揭示的是通过提升政党政治自觉、增强政党内在能动、实现政党价值创造的政党文明演进机理。当代中国政党政治的根本性质和历史使命,决定了政党治理体系是国家治理体系的核心内容,政党治理能力是国家治理能力的关键能力,直接影响着中国式现代化的发展方向和建设质量。

关键词：中国共产党中国式现代化政党治理现代化

维普期刊数据库