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Chinese Journal of Chemical Engineering 2018年第12期26卷 2573-2580页

作者： Youchang Wang shaoming zhou Jinhui Tang Yun Chen Libo Li Key Laboratory of Heat Transfer Enhancement and Energy Conservation of Ministry of Education School of Chemistry and Chemical Engineering South China University of Technology

Liquid–liquid equilibrium(LLE) data were measured for the ternary system of water + resorcinol + mesityl oxide under atmospheric pressure at temperatures of(298.2, 323.2, 333.2, 343.2 and 353.2) K. The reliability of the experimental data was verified by the Hand and Bachman equations. The distribution coefficient and selectivity were calculated from the experimental LLE data, which showed high efficiency of mesityl oxide extracting resorcinol from the aqueous solution. The NRTL and UNIQUAC models were employed to fit the measured experimental LLE data and yield corresponding binary interaction parameters.

关键词： Liquid-liquid equilibrium Mesityl oxide Resorcinol NRTL UNIQUAC

Salt effect on the liquid–liquid equilibrium of the ternary (water + phenol + methyl isobutyl ketone) system: Experimental data and correlation

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Chinese Journal of Chemical Engineering 2019年第1期27卷 168-173页

作者： Yun Chen Kangning Xiong Shuai Shen Huimin Wang shaoming zhou Libo Li Department of Chemistry and Chemical Engineering South China University of Technology State Key Laboratory of Pulp and Paper Engineering South China University of Technology

The effects of NaCl, KCl and Na_2SO_4 on the liquid–liquid equilibrium(LLE) data for the ternary system, water+ phenol + methyl isobutyl ketone, were determined at 0.101 MPa and 333.15 K and 343.15 *** nonrandom two-liquid(NRTL) model was used to correlate the experimental data and to yield corresponding binary interaction parameters for these salt containing *** Hand and Othmer–Tobias equations were used to confirm the dependability of the determined LLE data in this *** coefficient and selectivity were used to evaluate the extraction performance of methyl isobutyl ketone with the existence of *** magnitude of salt effect on the water + phenol + methyl isobutyl ketone(MIBK) system is in the following order: Na_2SO_4>NaCl>KCl.

关键词： Liquid-liquid equilibrium Methyl isobutyl ketone Salt effect Phenol

基于Rotterdam CT评分评估的颅脑损伤术中控制性减压的临床应用价值

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中华神经创伤外科电子杂志 2024年第1期10卷 16-21页

作者：李鑫刘炳辉程名王凡刘玉明周绍明湖南省脑科医院(湖南省第二人民医院)神经外科长沙410015

目的观察控制性减压技术治疗以鹿特丹(Rotterdam)CT评分为评估基础的不同程度颅脑损伤(TBI)的临床效果。方法选取湖南省脑科医院神经外科自2019年9月至2022年9月收治的TBI后严重颅高压需行去骨瓣减压手术的患者100例,采用随机数字表法... 详细信息

目的观察控制性减压技术治疗以鹿特丹(Rotterdam)CT评分为评估基础的不同程度颅脑损伤(TBI)的临床效果。方法选取湖南省脑科医院神经外科自2019年9月至2022年9月收治的TBI后严重颅高压需行去骨瓣减压手术的患者100例,采用随机数字表法将患者分为试验组(控制性减压)和对照组(快速减压),每组50例。所有患者术前行Rotterdam CT评分辅助评估,术后3个月随访,比较2组患者术中各Rotterdam CT分值区间一过性脑膨出发生率及预后情况。结果试验组Rotterdam CT 4~6分的脑膨出发生率低于对照组,差异有统计学意义(P<0.05)。随访3个月,40例患者预后良好,其中试验组27例,对照组13例,试验组预后良好率高于对照组,差异有统计学意义(P<0.05)。试验组各Rotterdam CT分值段(5~6分)GOS评分均高于对照组,差异有统计学意义(P<0.05)。结论严重颅脑损伤患者术中脑膨出的发生与术前高颅压状态有关,对颅内压失代偿需去骨瓣患者采用分阶段、分步骤的控制减压操作,可明显降低围术期并发症的发生率,改善预后。

关键词：颅脑损伤鹿特丹CT评分控制性减压快速减压预后

Two novel mutations in the SI gene associated with Congenital sucrase-isomaltase deficiency

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Two novel mutations in the SI gene associated with Congenita...

第二十三次全国儿科中西医结合学术会议

作者： Jianli zhou Xia Qian Huabo Cai shaoming zhou Division of Gastroenterology Shenzhen Children’s Hospital

Background: Congenital sucrase-isomaltase deficiency(CSID) is an autosomal recessive inherited disease leading to maldigestion of disaccharides,which is associated with the mutation of sucrase-isomaltase(SI) *** prevalence of CSID in the Chinese population is unknown and there are only three cases reported in china without genetic study. Case presentation:We report the case of a fourteen-month-old male infant who was admitted for chronic diarrhea and failure to thrive that began after food diversification. After approval from the clinical research ethics committee and informed consent was obtained, we chose whole exome sequencing to identify the mutations in this patient. As a result,two heterozygous mutations in the SI, c.2626 C>T(p.Q876*) and c.2872 C>T(p.R958 C) wereidentified and confirmed by Sanger sequencing, which were the novel mutations without reported. Conclusion: We experienced a novel case with the mutations in the SI gene that caused CSID, which provides valuable experience for clinic.

关键词： Congenital sucrase-isomaltase deficiency mutation gene

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论产品策略的风险防范

科技管理研究 2006年第8期26卷 118-120,127页

作者：龚振周少明华南理工大学工商管理学院广东广州510640

阐述企业进行市场营销活动所遇到的产品策略风险的含义和类型,并在市场营销风险防范一般方法的基础上,对产品风险进行具体分析,提出各种相应的防范技术和策略。

关键词：产品风险产品风险识别产品风险衡量产品风险控制产品风险预警

电迁移对Ni/Sn/Ni-P焊点界面反应的影响

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稀有金属材料与工程 2012年第10期41卷 1785-1789页

作者：陈雷达周少明黄明亮大连理工大学辽宁大连116024

研究了温度为150℃,电流密度为5.0×103A/cm2的条件下电迁移对Ni/Sn/Ni-P(Au)线性接头中界面反应的影响。结果表明电流方向对Ni-P层的消耗起着决定作用。当Ni-P层为阴极时,电迁移加速了Ni-P层的消耗,即随着电迁移时间的延长,Ni-P层的消... 详细信息

研究了温度为150℃,电流密度为5.0×103A/cm2的条件下电迁移对Ni/Sn/Ni-P(Au)线性接头中界面反应的影响。结果表明电流方向对Ni-P层的消耗起着决定作用。当Ni-P层为阴极时,电迁移加速了Ni-P层的消耗,即随着电迁移时间的延长,Ni-P层的消耗显著增加;电迁移100h后Ni-P层消耗了5.88μm,电迁移200h后Ni-P层消耗了13.46μm。在Sn/Ni-P的界面上形成了一层Ni2SnP化合物而没有观察到Ni3Sn4化合物的存在,多孔状的Ni3P层位于Ni2SnP化合物与Ni-P层之间。当Ni-P层为阳极时,在电迁移过程中并没有发现Ni-P层的明显消耗,在Sn/Ni-P的界面处生成层状的NiSn化合物,其厚度随着电迁移时间的延长而缓慢增加,电迁移200h后NiSn层的厚度达到1.81μm。

关键词：电迁移 Ni-P Ni 界面反应金属间化合物

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民俗研究的主观性及其他

民俗研究 2000年第3期 135-142页

作者：周少明澳大利亚墨尔本大学亚洲语言文化研究所

1988年， Evelyn s Rawski曾提到历史学家与人类学家研究中国丧葬习俗的方法及由此引起的一些争论。① Rawski指出，历史学家和人类学家研究中国丧葬仪式的方法是不同的。就人类学家而言，他们关心的主要问题是丧葬仪式本身。他们工... 详细信息

1988年， Evelyn s Rawski曾提到历史学家与人类学家研究中国丧葬习俗的方法及由此引起的一些争论。① Rawski指出，历史学家和人类学家研究中国丧葬仪式的方法是不同的。就人类学家而言，他们关心的主要问题是丧葬仪式本身。他们工作的主要途径是田野调查。人类学家相信，（共8页)

关键词：民俗学田野调查方法共时研究方法历时研究方法

Microstructure and Oxidation Behavior of ZrB_(2)-SiC Ceramics Fabricated by Tape Casting and Reactive Melt Infiltration

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无机材料学报 2024年第8期39卷 955-964页

作者： TAN Min CHEN Xiaowu YANG Jinshan ZHANG Xiangyu KAN Yanmei zhou Haijun XUE Yudong DONG shaoming State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

ZrB_(2)-based ceramics typically necessitate high temperature and pressure for sintering,whereas ZrB_(2)-SiC ceramics can be fabricated at 1500℃using the process of reactive melt infiltration with *** comparison to the conventional preparation method,reactive synthesis allows for the more facile production of ultra-high temperature ceramics with fine particle size and homogeneous *** this work,ZrSi_(2),B4C,and C were used as raw materials to prepare ZrB_(2)-SiC via combination of tape casting and reactive melt infiltration herein referred to as ZBC *** sample of ZrB_(2)-SiC was also prepared using ZrB_(2) and SiC as raw materials through an identical process designated as ZS *** analysis of both ceramic groups revealed smaller and more uniformly distributed particles of the ZrB_(2) phase in ZBC ceramics compared to the larger particles in ZS *** sets of ceramics underwent cyclic oxidation testing in the air at 1600℃for a cumulative duration of 5 cycles,each cycle lasting 2 *** of the oxidation behavior showed that both ZBC ceramics and ZS ceramics developed a glassy SiO_(2)-ZrO_(2) oxide layer on their surfaces during the *** layer severed as a barrier against *** ZBC ceramics,ZrO_(2) is finely distributed in SiO_(2),whereas in ZS ceramics,larger ZrO_(2) particles coexist with glassy SiO_(2).The surface oxide layer of ZBC ceramics maintains a dense structure because the well-dispersed ZrO_(2) increases the viscosity of glassy SiO_(2),preventing its crystallization during the ***,some SiO_(2) in the oxide layer of ZS ceramics may crystallize and form a eutectic with ZrO_(2),leading to the formation of ZrSiO_(4).This leads to cracking of the oxide layer due to differences in thermal expansion coefficients,weakening its barrier *** analysis of the oxidation resistance shows that ZBC ceramics exhibit less increase in oxide layer thickness and mass compared to ZS ceramics,su

关键词： ultra-high temperature ceramic ZrB2-SiC oxidation behavior reactive melt infiltration

合并重度脂肪肝的迟发型多种酰基辅酶A脱氢酶缺乏症的临床表现及基因分析

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中华医学遗传学杂志 2016年第2期33卷 191-194页

作者：代东伶文飞球周少明陈淑丽广东省深圳市儿童医院消化内科 518036

目的对一例青少年期发病的迟发型多种酰基辅酶A脱氢酶缺乏症（multipleaeyl-CoAdehydrogenasedeficiency，MADD）患儿的临床特点及ETFDH基因的突变情况进行分析。方法应用聚合酶链反应及Sanger直接测序法对患儿家系的3名成员进行ETFDH... 详细信息

目的对一例青少年期发病的迟发型多种酰基辅酶A脱氢酶缺乏症（multipleaeyl-CoAdehydrogenasedeficiency，MADD）患儿的临床特点及ETFDH基因的突变情况进行分析。方法应用聚合酶链反应及Sanger直接测序法对患儿家系的3名成员进行ETFDH基因的突变检测。结果患儿发病年龄为13岁10个月，除一过性乏力外无特殊表现。实验室检查肌酶、乳酸升高，血串联质谱分析发现多种酰基肉碱增高，尿气相色谱质谱分析示异戊二酰甘氨酸增高。肝脏磁共振氢谱示重度脂肪肝，病理学符合脂肪肝改变。基因检测发现ETFDH基因存在两个杂合错义突变，分别为c．250G〉A（***84Thr），c．353G〉T（***118Phe）。患儿被确诊为迟发型MADD。给予大剂量维生素B2治疗后病情迅速好转。结论c．250G〉A杂合突变是导致迟发型MADD的热点突变之一，而C．353G〉T为新发现的突变位点。临床上，对于有乏力等活动能力减低、肝酶及血脂异常等表现者，需警惕多种酰基辅酶A脱氢酶缺乏症的可能性。

关键词：戊二酸血症脂肪酸代谢脂肪肝肉碱

脂质代谢相关基因变异与肥胖儿童非酒精性脂肪肝易感性分析

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临床儿科杂志 2017年第4期35卷 241-246页

作者：代东伶周少明柳国胜文飞球周建利深圳市儿童医院广东深圳518036 暨南大学第一医院广东广州510630

目的探讨儿童脂质代谢相关基因变异与非酒精性脂肪肝(NAFLD)易感性。方法纳入6~18岁的肥胖伴脂肪肝儿童,进行超声检查、常规体检及生化检测,并提取外周血DNA,对36个脂质代谢相关目标基因进行二代测序,分析这些基因变异与脂肪肝的相关性... 详细信息

目的探讨儿童脂质代谢相关基因变异与非酒精性脂肪肝(NAFLD)易感性。方法纳入6~18岁的肥胖伴脂肪肝儿童,进行超声检查、常规体检及生化检测,并提取外周血DNA,对36个脂质代谢相关目标基因进行二代测序,分析这些基因变异与脂肪肝的相关性。结果符合纳入标准的368例肥胖儿童中检出NAFLD 183例,占比为49.7%。在肥胖儿童中随机选取NAFLD及non-NAFLD各100例,NAFLD儿童的体质量、腰围、丙氨酸氨基转移酶(ALT)、三酰甘油(TG)、胆固醇、低密度脂蛋白(LDL)和载脂蛋白B(ApoB)均高于non-NAFLD儿童,两组比较差异有统计学意义(P均0.05);两组的胆红素水平均在正常范围。Logistic回归分析发现,编码微粒体三酰甘油转运蛋白(MTTP或MTP)的基因MTTP rs2306986(OR=2.70,95%CI:1.38~5.27)、MTTP rs 3792683(OR=7.34,95%CI:2.04~26.50)及编码含patatin样磷脂酶域3的基因PNPLA3rs 738409位点变异(OR=2.11,95%CI:1.31~4.48)是影响NAFLD发生的独立危险因素。结论MTTP rs 2306986、MTTP rs 3792683、PNPLA3 rs 738409基因变异可能增加儿童NAFLD易感性。

关键词：基因学脂质代谢非酒精性脂肪肝肥胖单核苷酸多态性