检索结果-南通市图书馆

桥梁结构刚度对高速列车—轨道—桥梁耦合系统动力特性的影响

在线全文

学校读者我要写书评

暂无评论

中国铁道科学 2012年第1期33卷 19-26页

作者：翟婉明王少林西南交通大学牵引动力国家重点实验室四川成都610031

桥梁结构刚度对高速列车—轨道—桥梁耦合系统的动力学特性具有重要的影响,直接关系到桥上列车的行车安全性和运行平稳性。基于列车—轨道—桥梁动力相互作用理论,以高速铁路常用的简支箱梁桥和双块式无砟轨道为研究对象,采用列车—轨... 详细信息

桥梁结构刚度对高速列车—轨道—桥梁耦合系统的动力学特性具有重要的影响,直接关系到桥上列车的行车安全性和运行平稳性。基于列车—轨道—桥梁动力相互作用理论,以高速铁路常用的简支箱梁桥和双块式无砟轨道为研究对象,采用列车—轨道—桥梁动力学仿真通用软件TTBSIM2.0,研究桥梁结构刚度对高速列车—轨道—桥梁耦合系统动力性能的影响规律。结果表明:当桥梁梁体的刚度或者桥墩的横向刚度不足时,车辆和桥梁的相关动力性能指标将随着刚度的减少而急剧增大,严重影响列车过桥时的安全性和平稳性;当梁体垂向刚度不足时,有可能会引发车桥共振现象;当桥梁结构刚度满足设计规范要求时,车桥系统动力响应指标随刚度变化不明显,此时行车速度和轨道不平顺成为影响行车安全性和平稳性的主要因素。

关键词：高速铁路桥梁结构刚度列车—轨道—桥梁耦合振动动力特性

Rapid Access to Chiralα-Alkylated Azacycles via NiH-Catalyzed Asymmetric Migratory Hydroalkylation of N-Heterocyclic Alkenes

在线全文

学校读者我要写书评

暂无评论

CCS Chemistry 2024年第4期6卷 898-904页

作者： Changpeng Chen Wenqing Guo Deyong Qiao Junqian Zhou You wang shaolin Zhu State Key Laboratory of Coordination Chemistry Jiangsu Key Laboratory of Advanced Organic MaterialsChemistry and Biomedicine Innovation Center(ChemBIC)School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210093 School of Chemistry and Chemical Engineering Henan Normal UniversityXinxiang 453007 Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs Shanghai Jiao Tong UniversityShanghai 200240

Asymmetric migratory hydrofunctionalization of isomeric mixtures of alkenes provides a complementary approach for the selective introduction of a functional group into a remote C(sp3)-H ***,the simultaneous control of both regio-and enantioselectivity in this migratory process is a ***α-alkyl-substituted azacycles are key motifs in pharmaceuticals,natural products,and ***,we report a NiH-catalyzed asymmetric migratory hydroalkylation process for their efficient and selective *** this process,easily available isomeric mixtures of N-heterocyclic alkenes can be directly employed as starting materials,convergently delivering a variety of enantioenrichedα-alkylated azacycles with high levels of regio-and *** synthetic utility of this transformation is demonstrated by the facile synthesis of two bioactive alkaloids,(+)-connine and(R)-*** obtained chiralα-alkylated azacycles also readily undergo diverse derivatization,such as deconstructive halogenation and ring contraction.

关键词： alkenes alkylation asymmetric catalysis isomerization nickel

Molecular characterization of bla_(NDM)-harboring plasmids reveal its rapid adaptation and evolution in the Enterobacteriaceae

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

One Health Advances 2023年第1期1卷 26-40页

作者： Yiming Li Yuying Yang Yifei wang Timothy RWalsh shaolin wang Chang Cai Institute of Veterinary Medicine Jiangsu Academy of Agricultural SciencesNanjing 210014China Guangdong Laboratory for Lingnan Modern Agriculture Guangzhou 510642China National Key Laboratory of Veterinary Public Health and Safety College of Veterinary MedicineChina Agricultural University2nd West Yuanmingyuan RdBeijing 100193China College of Animal Science Wenzhou Vocational College of Science&TechnologyZhejiang ProvinceWenzhou 325006China Ineos Oxford Institute for Antimicrobial Research(IOI) University of OxfordOxford OX13REUK College of Veterinary Medicine Murdoch UniversityMurdochWestern Australia 6150Australia

Carbapenem is one of the few available drugs to treat multidrug-resistance Gram-negative bacteria ***,the plasmid-mediated spread of the carbapenem resistance gene bla_(NDM) poses a significant threat to public health,requiring global monitoring and ***,we used both short-read(n=2461)and long-read(n=546)sequencing data to characterize the global distribution of bla_(NDM).We analyzed the replicon type of bla_(NDM)-positive plasmids and found that the dominant plasmid type was different in diverse geographical *** bla_(NDM)gene has been transferred across diverse countries,its genetic backgrounds are highly conserved,and the mobile genetic element ISAba125,IS5,and IS26 may play an important role in the mobilization of bla_(NDM).A significant association was observed between host origin and gene presence/deletion variation on IncX3 plasmid,which may be a key factor in the bacterial adaption to diverse *** this study,we analyzed the diversity,distribution and transmission of bla_(NDM)-positive plasmids from a global perspective,and emphasize the importance of plasmid analysis for understanding the evolution and adaptation of bla_(NDM)-positive plasmids and their co-evolution with bacterial genomes(resistome).

关键词： bla_(NDM) Plasmids Bacterial genomics Carbapenem resistance

Genomic Insight into the Antimicrobial Resistance of Streptococcus Suis-Six Countries,2011-2019

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China CDC weekly 2021年第47期3卷 994-998页

作者： Lichao Ma Wanjiang Zhang Jingyun Ma Qingpo Cui Chaoyang Zhang Peng Zhang Chengtao Sun Huarun Sun Yao Zhu shaolin wang Shuangyang Ding Gongzheng Hu Zhangqi Shen College of Veterinary Medicine China Agricultural UniversityBeijingChina Harbin Veterinary Research Institute Chinese Academy of Agricultural SciencesHarbinHeilongjiangChina College of Animal Science South China Agricultural UniversityGuangzhouGuangdongChina College of Veterinary Medicine Henan Agricultural UniversityZhengzhouHenanChina

Summary What is already known on this topic?Streptococcus suis(***)is a zoonotic pathogen causing disease in humans and animals,and the emergence of its increased resistance to antimicrobial agents has become a signif... 详细信息

关键词： suis Streptococcus resistance

Transmission of Carbapenem Resistance Between Human and Animal NDM-Positive Escherichia coli Strains

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Engineering 2022年第8期8卷 24-33页

作者： Yingbo Shen Fupin Hu Yongqiang wang Dandan Yin Lu Yang Yiqiang Chen Chunyan Xu Jiyun Li Junyao Jiang Xueyang wang Yulin Fu Dongyan Shao Dejun Liu Tengfei Ma Chang Cai Zhangqi Shen shaolin wang Juan Li Rong Zhang Yuebin Ke Congming Wu Jianzhong Shen Timothy R.Walsh Yang wang Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety College of Veterinary MedicineChina Agricultural UniversityBeijing 100193China CAS Key Laboratory of Pathogenic Microbiology and Immunology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China Institute of Antibiotics&Key Laboratory of Clinical Pharmacology of Antibiotics(MoH) Huashan HospitalFudan UniversityShanghai 200040China Department of Preventive Veterinary Medicine College of Veterinary MedicineChina Agricultural UniversityBeijing 100193China State Key Laboratory of Animal Nutrition College of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China College of Animal Science and Technology College of Veterinary MedicineZhejiang A and F UniversityHangzhou 311300China State Key Laboratory for Infectious Disease Prevention and Control Collaborative Innovation Center for Diagnosis and Treatment of Infectious DiseaseNational Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and Prevention(CDC)Beijing 102206China The Second Affiliated Hospital of Zhejiang University Zhejiang UniversityHangzhou 310009China Key Laboratory of Genetics&Molecular Medicine of Shenzhen Shenzhen Center for Disease Control and PreventionShenzhen 518055China Department of Zoology University of OxfordOxford OX13SZUK

Although carbapenem use is prohibited in animals in China,carbapenem-resistant Escherichia coli(CREC),especially New Delhi metallo-β-lactamase(NDM)-producing strains,are widely prevalent in foodproducing *** present,the impact of livestock-associated CREC strains on human populations at the national level is ***,we conduct a retrospective cross-sectional study to investigate the prevalence of CREC from clinical settings across 22 Chinese provinces or municipalities and analyze anthropogenic factors associated with their *** also ascertain the blaNDMand blaKPCabundance among pig and chicken farms and present a detailed genomic framework for CREC of animal and human ***,631/29799(2.1%)clinical Escherichia coli(***)isolates were identified as *** analysis revealed that being male,an age below 1,an age between 13 and 18,provinces with greater chicken production,and provinces with higher pig production were associated with higher odds of CREC *** general,73.8%(n=45/61)of pig farms and 62.2%(n=28/45)of chicken farms had a blaNDMabundance of 1×10^(-5)to 1×10^(-3)and 1×10^(-3)to 1×10^(-2),*** all the Chinese NDM-positive ***(n=463)available at the National Center for Biotechnology Information(NCBI),the genomic analysis revealed that blaNDM-5and Inc X3 were the predominant carbapenemase gene-plasmid combination,while a highly homogeneous relationship between NDM-positive isolates from humans and animals was demonstrated at the plasmid and core genome *** the findings suggest frequent CREC transmission between humans and animals,indicating that further discussions on the use of antibiotics in animals and humans are needed,both in China and across the globe.

关键词： Carbapenem resistance Escherichia coli blaNDM-5 One Health Antimicrobial resistance transmission

双重时变“泰勒规则”在中国货币政策操作中的检验

在线全文

学校读者我要写书评

暂无评论

南方经济 2015年第6期44卷 67-83页

作者：王少林广东财经大学金融学院

本文在双重时变设定中考察泰勒规则在中国的适用性,一方面参数时变性体现的是央行对经济冲击的响应强度变化,另一方面货币政策目标维数的时变性体现的是央行在不同时期核心政策目标的转移。实证结果表明:(1)影响央行利率调整的政策目标... 详细信息

本文在双重时变设定中考察泰勒规则在中国的适用性,一方面参数时变性体现的是央行对经济冲击的响应强度变化,另一方面货币政策目标维数的时变性体现的是央行在不同时期核心政策目标的转移。实证结果表明:(1)影响央行利率调整的政策目标维度存在时变性,尤其体现在汇率对利率调整的阶段性影响;(2)利率对通货膨胀的响应并不充分,不符合严格意义上的泰勒规则,但在通货紧缩时期,利率调整在一定程度上能缓解通货紧缩,利率对通货膨胀与通货紧缩的反应存在明显的不对称性。基于我国货币供给的内生性,本文建议,我国应该加快推进利率市场化进程,培育以利率为货币政策中间变量的金融环境。

关键词：泰勒规则时变参数时变目标维数

在线全文

学校读者我要写书评

暂无评论

中国经济新常态的量化识别与形成原因

南方经济 2017年第7期46卷 1-16页

作者：王少林广东财经大学金融学院

新常态指经济增长速度出现了结构性变化并呈现新的稳态形式,是当前和未来一段时间我国经济发展的国家战略判断。文章尝试基于条件马尔可夫状态转移模型对自从改革开放以来中国经济进行划分,量化识别中国经济进入新常态的历史时刻,为从... 详细信息

新常态指经济增长速度出现了结构性变化并呈现新的稳态形式,是当前和未来一段时间我国经济发展的国家战略判断。文章尝试基于条件马尔可夫状态转移模型对自从改革开放以来中国经济进行划分,量化识别中国经济进入新常态的历史时刻,为从经验分析角度深入分析新常态奠定基础。实证结果显示,1995年第2季度至2005年第4季度为中国经济旧常态时期,2008年第1季度至今为中国经济新常态时期,其余为过渡期。此外,文章进一步应用时变参数模型从要素禀赋视角探讨了中国经济新常态形成原因,发现各要素对经济增长的作用强度并未发生较大改变,经济新常态的形成主要源自于就业人口与全要素生产率的增长率下降。

关键词：新常态马尔可夫状态转移模型全要素生产率要素禀赋

The Rationality Inspection Global Method of Measuring Data

在线全文

学校读者我要写书评

暂无评论

The Rationality Inspection Global Method of Measuring Data

2015 5th International Conference on Computer Sciences and Automation Engineering(ICCSAE 2015)

作者： Zhao Liu Maodong Pan shaolin wang Jiangtao Wei China Satellite Maritime Tracking and Control Department School of Mathematics Sciences University of Science and Technology of China

Least square method for polynomial extrapolation is one of data rationality inspection methods that are often used to identify outliers. However, the method is local and only inspects the rationality of current data points. If the outliers are accepted before, the method can cause the following normal points to be abandoned and the abnormal points to be received, which will lead to the accumulation of errors. Moreover, because of the method needs to accumulate points before inspection, the initial data points cannot be inspected. To this end, this paper presents a global data nationality inspection algorithm. The method is fast and accurate, and can effectively eliminate the accumulated error in global.

关键词： Rationality inspection least square global method accumulated error

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

居民通胀预期的偏差、异质性与政策干预

财贸研究 2017年第11期28卷 61-71页

作者：王少林广东财经大学金融学院广东广州510320

预期的重要性在于其存在自我实现的能力,对其管理也随之成为当前宏观经济管理的突出体现。从存在性和偏差方向两个维度判断我国居民通胀预期的偏差,并进一步应用时变参数模型分析不同群体通胀预期自我实现的异质性以及央行如何对不同群... 详细信息

预期的重要性在于其存在自我实现的能力,对其管理也随之成为当前宏观经济管理的突出体现。从存在性和偏差方向两个维度判断我国居民通胀预期的偏差,并进一步应用时变参数模型分析不同群体通胀预期自我实现的异质性以及央行如何对不同群体通胀预期做出反应。结果表明:我国居民通胀预期存在偏差,呈现"好动"倾向;居民预期未来物价"下降"比预期未来物价"上升"自我实现能力更强,但是存在较大的时变性;不论是在利率还是在货币供应量方面,央行对居民预期未来物价"上升"都存在较高容忍度,而对居民预期未来物价"下降"反应表现出更为迅速、更强和较为一致的特征。

关键词：通胀预期货币政策异质性偏差