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口服脂肪耐量试验的优化研究

中华内分泌代谢杂志 2024年第3期40卷 204-211页

作者：侯艺林马倩宋光耀侯晓宇卢亚敏田培培张婷雪刘丹丹曾少静冀金蕊任路平河北医科大学附属河北省人民医院内分泌科石家庄050051 河北医科大学附属河北省人民医院检验科石家庄050051 河北医科大学附属河北省人民医院核医学科石家庄050051

目的本研究旨在对比不同试验餐对餐后三酰甘油的影响,优化口服脂肪耐量试验标准餐配方和采血方案。方法本研究为前瞻性、开放标签、随机、交叉试验。2023年3月在河北省人民医院招募志愿者36名,经过健康查体和口服葡萄糖耐量试验,26名健... 详细信息

目的本研究旨在对比不同试验餐对餐后三酰甘油的影响,优化口服脂肪耐量试验标准餐配方和采血方案。方法本研究为前瞻性、开放标签、随机、交叉试验。2023年3月在河北省人民医院招募志愿者36名,经过健康查体和口服葡萄糖耐量试验,26名健康志愿者符合入选标准(男性11名,女性15名),平均年龄(39.08±4.56)岁。每位志愿者分别接受75 g蛋白餐、75 g脂肪餐、700 kcal固定热量高脂混合餐及根据10 kcal/kg体重调整热量的高脂混合餐试验,每次试验前普通饮食洗脱1周。在每次试验的空腹和餐后1、2、3、4、5、6 h采血,取血清检测三酰甘油、总胆固醇、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、血糖、胰岛素。分析不同试验餐餐后代谢指标随时间变化情况,比较两种混合餐的餐后代谢反应差异。结果蛋白餐、脂肪餐、固定热量高脂混合餐、调整热量高脂混合餐分别使餐后三酰甘油升高22.45%、115.40%、77.14%、63.63%,胰岛素升高560.43%、85.69%、554.18%、598.97%,总胆固醇、LDL-C、HDL-C降低5.64%~21.81%,血糖变化较小。代谢指标的主要变化发生在4 h以内。比较2种高脂混合餐后三酰甘油的特征,差异无统计学意义(P>0.05)。结论以700 kcal固定热量高脂混合餐为标准餐,在空腹和餐后1、2、3、4 h分别采血检测血脂水平,可作为口服脂肪耐量试验的优化方案。

关键词：三酰甘油口服脂肪耐量试验餐后血脂健康人群心血管疾病

Structure design and compression experiment of the supporting node for JUNO PMMA detector

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Radiation Detection Technology and Methods 2020年第3期4卷 345-355页

作者： Xiaohui Qian Xiaoyan Ma Yuekun Heng Wei He Zhonghua Qin Yuesheng Tang Jianxia Xiao Gaofeng Zhang Wei Cheng Lei Li Jian Tang Tao Chen Chang Liu Zian Zhu shaojing hou Yatian Pei Xiaoyu Yang Institute of High Energy Physics Chinese Academy of ScienceBeijing 100049China State Key Laboratory of Particle Detection and Electronics Beijing 100049China University of Chinese Academy of Science Beijing 100049China Jiangsu Domchamp New Material Technology Co. LtdTaixing City 225400China Sun Yat-sen University Guangzhou City 510080China China Academy of Building Research Beijing 100013China

Introduction Jiangmen Underground Neutrino Observation is going to build a huge polymethyl methacrylate(PMMA)detector to hold 20,000 tons of liquid scintillator to capture neutrinos in a 700-m underground cave.This PMMA detector has a spherical shape with an inner diameter of 35.4 m and is supported by an outside stainless steel structure through 590 supporting nodes.The maximum compression force applied to these supporting nodes would be about 150 kN when the detector is running.Method This paper focuses on the design and validation of the PMMA supporting node and compares the effects of two gaskets(round gasket and ring gasket)on the supporting node stress and ultimate compression load.An innovative PMMA supporting node structure is first proposed,and a 1/4 symmetric model with the material nonlinearity and frictional contact boundary is established in the finite element analysis(FEA).Results The FEA results show that the principal stress of the structure is less than 3.5 MPa and the Mises stress is less than 5.5 MPa.The stress and deformation at the groove of the supporting node using the ring gasket are smaller than that using the round gasket.The compression experiments of the supporting node using two types of gaskets were conducted to study the effect of gaskets on the ultimate compression load of supporting node.The ultimate compression load of the supporting node with ring gasket is larger than 900 kN,which is six times of design load.In a comparison of experimental results with FEA,the maximum difference is 15.78%,demonstrating the validity of FEA results.Through the material test of PMMA and experiment of the PMMA supporting node,it is known that PMMA is a brittle material and it is very sensitive to sharp corner defects that should be avoided in the design of PMMA structure.

关键词： JUNO PMMA detector PMMA supporting node Compression experiment Brittle material

Quarantine,distress and interpersonal relationships during COVID-19

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General Psychiatry 2020年第6期33卷 437-441页

作者： Robin Goodwin Wai Kai hou shaojing Sun Menachem Ben-Ezra Department of Psychology University of WarwickCoventryUK Department of Psychology The Education University of Hong KongHong KongHong Kong Department of Journalism Fudan UniversityShanghaiShanghaiChina Department of Social Work Ariel UniversityArielIsrael

Novel zoonosis COVID-19 first emerged in Wuhan,China,but rapidly spread to the other regions in China.The spread of this severe acute respiratory syndrome led to the quarantine of 60 million Chinese citizens.Such isolation measures have been associated with increased depression,stress and emotional disturbance.1-3 However,major traumatic events can amplify both positive and negative aspects of interpersonal relations,leading to competing narratives of both harm and enhancem ent.4 Quarantine can create family dependencies,threaten livelihoods and lead to the stigmatisation of those infected/b School closures and disruption of family care seriously disrupt regular domestic practices.

关键词： closure measures Quarantine

A new insight into the stability of nanofiber electrodes used in proton exchange membrane fuel cells

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Journal of Energy Chemistry 2020年第3期29卷 126-132页

作者： Yanyan Gao Ming hou Liang He Manman Qi Haiping Chen shaojing Hong Yongyi Jiang Zhigang Shao Baolian Yi Dalian National Laboratory for Clean Energy Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina University of Chinese Academy of Sciences Beijing 100039China Guangzhou Automobile Group Co.Ltd. Automotive Engineering InstituteGuangzhou 510080GuangdongChina Anhui Mingtian Hydrogen Energy Technology Co.Ltd. Lu’an 237000AnhuiChina

The nanofiber electrodes have been considered as promising candidates for commercial proton exchange membrane fuel cells due to their high catalyst utilization and enhanced mass transport efficiency.However,for the first time our research determined that the nanofiber electrodes were restricted by the poor chemical stability of the polymer carriers.To gain further insight into the durability of nanofiber electrodes,both cyclic voltammetry aging tests and Fenton’s tests were conducted.Similar to previous reports,our research demonstrated that nanofiber electrodes showed remarkable stability in the cyclic voltammetry aging process.However,Fenton’s tests indicated that nanofibers in the electrodes would decompose easily while being attacked by reactive oxygen species such as HO·or HOO·,which greatly limits their practicability and reliability.The different performances under the two tests also demonstrated that the cyclic voltammetry aging protocols,which have been applied extensively,cannot well mirror the real operating conditions of fuel cells.

关键词： PEMFC Nanofiber electrode Stability

Spatial Pattern Characteristics and Influencing Factors of National Forest Cities in China

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Journal of Landscape Research 2019年第5期11卷 35-40页

作者： HAN Jing TANG Beipei hou shaojing College of Urban and Environmental Sciences Northwest UniversityXi’anShaanxi 710127China Xi’an Natural Resources and Planning Bureau Chang’an BranchXi’anShaanxi 710100China

In view of the deficiency of national forest cities in the exploration of spatial pattern and influencing factors,this paper adopted the methods of nearest neighbor analysis,kernel density analysis and unbalanced index calculation to analyze the spatial agglomeration pattern and spatial differentiation pattern of national forest cities.The factors affecting the selection and distribution of national forest cities were investigated by using the geographic detector and GWR model.The research results show that:① National forest cities show a spatial aggregation pattern of “east and west sparse,gradient change”,whose distribution is closely related to the climatic area;② The number of national garden cities,forest coverage rate,urbanization rate and local general budget income are four factors that have significant influence on the selection and distribution of national forest cities;③ The four significant influencing factors all have different degrees of spatial non-stationarity,and their two-factor and nonlinear enhancement effects can be generated after two interactions,among which the enhancement effect is the most obvious when the local general budget income interacts with other factors.

关键词： National forest cities Distribution pattern Influencing factors GeoDetectors GWR model

基于BI-GRU改进的Seq2Seq网络的变压器油中溶解气体浓度预测方法

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电力自动化设备 2022年第3期42卷 196-202,217页

作者：汤健侯慧娟陈洪岗王劭菁盛戈皞江秀臣上海交通大学电气工程系上海200240 国网上海市电力公司电力科学研究院上海200437

基于门控循环单元(GRU)构建双向多层门控循环单元,并引入编码器-解码器结构搭建Seq2Seq网络模型,通过优化神经元及神经网络结构提取时序数据依赖关系。同时引入注意力机制和Scheduled Sampling算法,自动获取与当前时刻预测输出显著相关... 详细信息

基于门控循环单元(GRU)构建双向多层门控循环单元,并引入编码器-解码器结构搭建Seq2Seq网络模型,通过优化神经元及神经网络结构提取时序数据依赖关系。同时引入注意力机制和Scheduled Sampling算法,自动获取与当前时刻预测输出显著相关的关键输入时间点,提高长时间预测的精度。变压器正常运行状态下的气体浓度预测算例结果表明,与基于简单GRU模型及简单Seq2Seq模型的方法相比,所提方法的预测误差更低且预测的发展趋势更符合真实值;变压器异常运行状态下的气体浓度预测算例结果表明,所提方法的平均相对误差和最大相对误差相比长短期记忆(LSTM)网络方法分别降低了0.73%和2.31%。

关键词：电力变压器油中溶解气体门控循环单元 Seq2Seq 注意力机制 Scheduled Sampling算法

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上海青浦优质稻米产业发展现状与对策研究

上海农业学报 2022年第5期38卷 119-123页

作者：侯绍靖钱益芳沙之敏曹林奎上海交通大学农业与生物学院上海200240 上海市青浦区农业技术推广服务中心上海201700

优质稻米产业是上海市青浦区现代农业主导产业,发展优质稻米产业是贯彻落实乡村振兴战略的重要措施。通过调查研究,分析青浦区优质稻米产业的发展现状和存在的问题,提出构建优质稻米标准化绿色生产体系、强化优质稻米品牌建设、组建优... 详细信息

优质稻米产业是上海市青浦区现代农业主导产业,发展优质稻米产业是贯彻落实乡村振兴战略的重要措施。通过调查研究,分析青浦区优质稻米产业的发展现状和存在的问题,提出构建优质稻米标准化绿色生产体系、强化优质稻米品牌建设、组建优质稻米产业化联合体、拓宽优质稻米的营销渠道等对策和建议,以期为上海青浦地区优质稻米产业发展提供参考。

关键词：青浦区优质稻米产业发展现状对策

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基于正交试验的玻璃壳热应力影响因素分析

机械工程学报 2019年第12期55卷 91-98页

作者：钱小辉马骁妍秦中华侯少静徐美杭张鹏朱自安中国科学院大学核探测与核电子学国家重点实验室北京100049 中国科学院高能物理研究所北京100049 中国科学院大学核技术及应用学院北京100049

为研究江门中微子试验(JUNO)光电倍增管(PMT)玻璃壳在温度载荷下的应力分布,以避免玻璃壳发生脆性破坏,对不同灌封胶材料下的玻璃壳热应力进行有限元模拟分析。采用正交试验方法,选取灌封胶材料属性参数中的弹性模量、泊松比和热膨胀系... 详细信息

为研究江门中微子试验(JUNO)光电倍增管(PMT)玻璃壳在温度载荷下的应力分布,以避免玻璃壳发生脆性破坏,对不同灌封胶材料下的玻璃壳热应力进行有限元模拟分析。采用正交试验方法,选取灌封胶材料属性参数中的弹性模量、泊松比和热膨胀系数作为研究因素,建立L25(53)正交表并得到25组数值模拟方案。对数值计算结果进行极差和方差分析,结果显示影响设计指标的主要因素为弹性模量和热膨胀系数,次要因素为泊松比。弹性模量对玻璃壳热应力有显著影响,热膨胀系数对玻璃壳热应力有一定影响,泊松比对玻璃壳热应力无显著影响。对各因素水平的算术平均值进行曲线拟合,提出基于拟合函数解析解的敏度分析方法来得到设计指标对各因素的敏感程度。结果表明,玻璃热应力对不同灌封胶材料的各参数敏感度不同。实际工程可针对最大敏度参数进行材料的改性工作,从而使得灌封胶材料的选用和改性更具有针对性和方向性,研究结果对实际工程具有极强的指导意义和参考价值。

关键词：热应力正交试验方差分析曲线拟合敏度分析

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一家族两代四例毛发-鼻-指(趾)综合征

中华皮肤科杂志 1992年第5期25卷 342-343页

作者：侯显曾冯惠明张绍景况学敏汤冰广州医学院第一附属医院皮肤科广州珠江华侨港澳同胞医院广东新会县古井中心卫生院

例1.先证者,男,20岁,未婚。以稀疏脱发6年为主诉于1991年4月2日就诊。病史:出生时体重3.5kg,鼻、指、趾未见异常,但头发比正常婴儿稀少。约14岁起,头发缓慢脱落,脱发程度随年龄增长而加重,近年更甚。开始脱发时,自觉手足变粗,长度不增加... 详细信息

例1.先证者,男,20岁,未婚。以稀疏脱发6年为主诉于1991年4月2日就诊。病史:出生时体重3.5kg,鼻、指、趾未见异常,但头发比正常婴儿稀少。约14岁起,头发缓慢脱落,脱发程度随年龄增长而加重,近年更甚。开始脱发时,自觉手足变粗,长度不增加,但不影响生产劳动。智力正常,为初中毕业生,成绩尚好。其父母非近亲结婚,本人为足月顺产第一胎。

关键词：鼻毛发综合征