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Journal of Iron and Steel Research International 2024年第2期31卷 501-518页

作者： Bao-sheng Liu Peng-fei Xu shao-hua Zhang Yan-rui Li Li-ming Mou Jia-li Li Yue-zhong Zhang Pei-mao Fu Fa-cai Shi College of Materials Science and Engineering Taiyuan University of Science and TechnologyTaiyuan030024ShanxiChina College of Chemical and Biological Engineering Taiyuan University of Science and TechnologyTaiyuan030024ShanxiChina Technical Center Taiyuan Iron and Steel(Group)Co.Ltd.Taiyuan030003ShanxiChina

The corrosion mechanism of 510L low alloy steel treated by acid-cleaned surface(ACS)and eco-pickled surface(EPS)techniques in three simulated solutions(S0:atmospheric environment;S1:soil environment;S2:industrial environment)and the influence of interaction between different corrosive anions on corrosion were *** results show that the total corrosion rates of samples in three simulated solutions were in order of S2>S0>S1,which is simultaneously correlated with initial corrosion dissolution processes as well as after the formation of corrosion ***3−will inhibit the initial corrosion owing to the formation of films,whereas HSO3−will accelerate the dissolutions of the matrix based on the synergistic action of HSO3−and Cl−.On the other hand,there is no significant difference in corrosion rates between the samples treated by ACS and EPS *** EPS technique that is safe,reusable and environmentally friendly can be further widely used in future work.

关键词： Corrosion mechanism Low alloy steel Simulated solution Surface technique Immersion time

Scalable production of mesoporous titanium nanoparticles through sequential flash nanocomplexation

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Chinese Chemical Letters 2024年第4期35卷 303-309页

作者： Feng Cui Fangman chen Xiaochun Xie chenyang Guo Kai Xiao Ziping Wu Yinglu chen Junna Lu Feixia Ruanb Chuanxu cheng Chao Yang Dan shao School of Biomedical Sciences and Engineering South China University of TechnologyGuangzhou International CampusGuangzhou 511442China Institutes for Life Sciences School of MedicineSouth China University of TechnologyGuangzhou 510006China School of Biology and Biological Engineering South China University of TechnologyGuangzhou 510006China Department of Orthopedics Academy of Orthopedics-Guangdong ProvinceOrthopedic Hospital of Guangdong ProvinceGuangdong Provincial Key Laboratory of Bone and Joint Degenerative DiseasesThe Third Affiliated Hospital of Southern Medical UniversityGuangzhou 510665China National Engineering Research Center for Tissue Restoration and Reconstruction South China University of TechnologyGuangzhou 510006China

Mesoporous titanium nanoparticles(MTNs) have emerged as an important porous semiconductor owning to their large surface area and unique electronic/optical properties. However, the fundamental research for rational manufacturing MTNs in a highly scalable manner remains a challenge. In this study, we report a two-step flash nanocomplexation(FNC) approach to large-scalable generate MTNs through the sequential combination of two multi-inlet vortex mixers. By optimizing the concentrated titanium precursor,polyethylene glycol(PEG)-functionalized silane amount and p H, we have been able to produce MTNs with small particle size(31.5 nm), larger surface area(416.9 m^(2)/g) and pore volume(0.59 cm^(3)/g). Different from the traditional MTNs bulk, FNC-produced MTNs exhibited well-controlled manner and exceptional photocatalytic and antibacterial properties. Importantly, the optimized MTNs outperformed commercial P25 not only in protecting ultraviolet A(UVA)-exposed skin, but also in treating P. aeruginosa-infected wound. We believe that the high controllability and scalability of sequential flash nanocomplexation method offers great opportunities in enhancing the performance of mesoporous titanium nanoparticles.

关键词： Mesoporous titanium nanoparticles Flash nanocomplexation Photocatalytic Antibacterial Sequential

Detection of SARS-CoV-2 based on artificial intelligence-assisted smartphone:A review

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Chinese Chemical Letters 2024年第7期35卷 25-34页

作者： Yunxin Li Jinghui Zhang Jisen chen Feng Zhu Zhiqiang Liu Peng Bao Wei Shen sheng Tang School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China Programme in Emerging Infectious Diseases Duke-NUS Medical SchoolSingapore 169857Singapore

In recent years,the application of smartphone in various fields has received great attention,and it has become a promising tool in virus detection,data processing and data *** the rapid spread of COVID-19 around the world,many traditional detection methods have been combined with smartphone to assist in the analysis and detection of the novel coronavirus(SARS-CoV-2),including electrochemistry,fluorescence and *** the gradual development of artificial intelligence(AI),the combination of AI and smartphone to analyze SARS-CoV-2 was also the focus of *** on the summary of the traditional methods combined with smartphone to detect SARS-CoV-2 virus,in addition to AI-based data processing,AI algorithms are also employed for SARS-CoV-2 detection *** review discussed both strategies and focused on the application of the *** combination of AI algorithm and smartphone to detect SARS-CoV-2 has high accuracy,which is more conducive to meeting the needs of portable *** addition,the classification of SARS-CoV-2 virus samples in biological fluids such as blood and saliva was also ***,this paper briefly discussed the limitations of using smartphone analysis to detect SARS-CoV-2,as well as the prospect and future development of virus *** conclusion,the detection methods based on smartphone and AI algorithms show great potential in the detection of SARS-CoV-2 and can be a valuable complement to traditional analysis methods.

关键词： COVID-19 SARS-CoV-2 virus Detection method Smartphone analysis Artificial intelligence

Zinc-based metal-organic frameworks as efficient carriers for anticancer drug to reduce toxicity and increase efficacy

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Rare Metals 2024年第10期43卷 5152-5163页

作者： Dong-Wei Ma Jing-sheng Lu Xiang-Xin Cao Yan-Wei cheng Gang Wang Zi-Qian Zhang Bo-cheng chen Ning Lin Qing chen College of Pharmacy Guangxi Scientific Research Center of Traditional Chinese MedicineGuangxi University of Chinese Medicine Guangxi Zhuang Yao Medicine Center of Engineering and Technology

The rational design of a specific co-drug delivery platform that can address the unavoidable resistance, toxic side effects and low targeting efficiency of traditional cancer treatments is of great ***, Zn-based MOF-zeolitic imidazole framework-90(ZIF-90) was selected as the drug delivery carrier, with the cancer therapeutic drug mercaptopurine(6-MP) and glucose oxidase(GOD) as the drug models, hyaluronic acid(HA) was used for protection and targeted delivery, which designed and fabricated an intelligent drug delivery platform(6-MP@ZIF-90@GOD@HA). This platform aims to reduce the toxic side effects of 6-MP and enhance its efficacy while improving the targeting ability of GOD,thereby further enhancing the treatment outcome. Notably,results from both in vitro and in vivo experiments demonstrate that the targeted synergistic chemo/reactive oxygen species(ROS)-mediated/starvation therapy inhibited the cancer cell growth while reducing the chemotherapy toxicity, which provides new possibilities for the development of more precise and effective treatment strategies.

关键词： Cancer treatment Combination therapy Drug delivery Metal-organic framework Reduced toxicity

Functional near-infrared spectroscopy in non-invasive neuromodulation

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Neural Regeneration Research 2024年第7期19卷 1517-1522页

作者： Congcong Huo Gongcheng Xu Hui Xie Tiandi chen Guangjian shao Jue Wang Wenhao Li Daifa Wang Zengyong Li Beijing Advanced Innovation Center for Biomedical Engineering Key Laboratory for Biomechanics and Mechanobiology of Ministry of EducationSchool of Biological Science and Medical EngineeringBeihang UniversityBeijingChina Beijing Key Laboratory of Rehabilitation Technical Aids for Old-Age Disability National Research Center for Rehabilitation Technical AidsBeijingChina School of Mechatronic Engineering and Automation Foshan UniversityFoshanGuangdong ProvinceChina School of Rehabilitation Engineering Beijing College of Social AdministrationBeijingChina Key Laboratory of Neuro-functional Information and Rehabilitation Engineering of the Ministry of Civil Affairs BeijingChina

Non-invasive cerebral neuromodulation technologies are essential for the reorganization of cerebral neural networks,which have been widely applied in the field of central neurological diseases,such as stroke,Parkinson’s disease,and mental *** significant advances have been made in neuromodulation technologies,the identification of optimal neurostimulation paramete rs including the co rtical target,duration,and inhibition or excitation pattern is still limited due to the lack of guidance for neural *** r,the neural mechanism unde rlying neuromodulation for improved behavioral performance remains poorly ***,advancements in neuroimaging have provided insight into neuromodulation *** near-infrared spectroscopy,as a novel non-invasive optical brain imaging method,can detect brain activity by measuring cerebral hemodynamics with the advantages of portability,high motion tole rance,and anti-electromagnetic *** functional near-infra red spectroscopy with neuromodulation technologies offe rs an opportunity to monitor the cortical response,provide realtime feedbac k,and establish a closed-loop strategy integrating evaluation,feedbac k,and intervention for neurostimulation,which provides a theoretical basis for development of individualized precise neuro *** aimed to summarize the advantages of functional near-infra red spectroscopy and provide an ove rview of the current research on functional near-infrared spectroscopy in transcranial magnetic stimulation,transcranial electrical stimulation,neurofeedback,and braincomputer ***,the future perspectives and directions for the application of functional near-infrared spectroscopy in neuromodulation are *** conclusion,functional near-infrared spectroscopy combined with neuromodulation may promote the optimization of central pellral reorganization to achieve better functional recovery form central nervous system

关键词： brain-computer interface cerebral neural networks functional near-infrared spectroscopy neural circuit neurofeedback neurological diseases neuromodulation non-invasive brain stimulation transcranial electrical stimulation transcranial electrical stimulation

The generation and use of animal models of osteosarcoma in cancer research

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Genes & Diseases 2024年第2期11卷 664-674页

作者： Feifei Pu Haoyu Guo Deyao Shi Fengxia chen Yizhong Peng Xin Huang Jianxiang Liu Zhicai Zhang Zengwu shao Department of Orthopedics Wuhan Hospital of Traditional Chinese and Western Medicine (Wuhan No.1 Hospital)Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022China Department of Orthopedics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022China Department of Radiation and Medical Oncology Zhongnan HospitalWuhan UniversityWuhanHubei 430071China Hubei Cancer Clinical Study Center Zhongnan HospitalWuhan UniversityWuhanHubei 430071China

Osteosarcoma is the most common malignant bone tumor affecting children and ***,the most common treatment is surgery combined with neoadjuvant *** the survival rate of patients with osteosarcoma has improved in recent years,it remains poor when the tumor(s)progress and distant metastases ***,better animal models that more accurately replicate the natural progression of the disease are needed to develop improved prognostic and diagnostic markers,as well as targeted therapies for both primary and metastatic *** present review described animal models currently being used in research investigating osteosarcoma,and their characteristics,advantages,and *** models may help elucidate the pathogenic mechanism(s)of osteosarcoma and provide evidence to support and develop clinical treatment strategies.

关键词： Animal model Cancer Osteosarcoma Pathogenic mechanism Translational research

Genetic Analysis of Structural Styles in the Makran Accretionary Wedge–Insight from Physical Simulations

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Journal of Ocean University of China 2024年第1期23卷 157-172页

作者： shao Longfei YU Fusheng GONG Jianming LIAO Jing YU Zhifeng TANG Liang chen Jiangong WANG Yuefeng NENG Yuan School of Earth Sciences China University of PetroleumBeijing 102249China State Key Laboratory of Petroleum Resources and Processing China University of PetroleumBeijing 102249China Qingdao Institute of Marine Geology China Geological SurveyQingdao 266071China China University of Petroleum–Beijing at Karamay Karamay 834000China

The Makran accretionary wedge has the smallest subduction angle among any accretionary prism in the world. The factors controlling the spacing and morphological development of its deep thrust faults, as well as the formation mechanism of shallow normal faults, remain unclear. Meanwhile, the factors affecting the continuity of plane faults must be comprehensively discussed. Clarifying the development characteristics and deformation mechanisms of the Makran accretionary wedge is crucial to effectively guide the exploration of gas hydrate deposits in the area. This study aims to interpret seismic data to identify typical structures in the Makran accretionary wedge, including deep imbricate thrust faults, shallow and small normal faults, wedge-shaped piggyback basins, mud diapirs with fuzzy and disorderly characteristics of reflection, décollements with a northward tilt of 1° – 2°, and large seamounts. Physical simulation-based experiments are performed to comprehensively analyze the results of the plane, section, and slices of the wedge. Results reveal that the distances between and shapes of thrust faults in the deep parts of the Makran accretionary wedge are controlled by the bottom décollement. The uplift of the thrust fault-related folds and the upwelling of the mud diapirs primarily contribute to the formation of small normal faults in the shallow part of the area. The mud diapirs originate from plastic material at the bottom, while those that have developed in the area near the trench are larger. Seamounts and mud diapirs break the continuity of fault plane distribution.

关键词： Makran accretionary wedge structural styles faults distribution physical simulation

Intensive management enhances mycorrhizal respiration but decreases free-living microbial respiration by affecting microbial abundance and community structure in Moso bamboo forest soils

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Pedosphere 2024年第2期34卷 508-519页

作者： Wenhao JIN Jiangfei GE Shuai shao Liyuan PENG Jiajia XING chenfei LIANG Junhui chen Qiufang XU Hua QIN State Key Laboratory of Subtropical Silviculture Zhejiang A&F UniversityHangzhou 311300China School of Environmental and Resource Sciences Zhejiang A&F UniversityHangzhou 311300China

Intensive management is known to markedly alter soil carbon(C)storage and turnover in Moso bamboo forests compared with extensive ***,the effects of intensive management on soil respiration(RS)components remain *** study aimed to evaluate the changes in different RScomponents(root,mycorrhizal,and free-living microorganism respiration)in Moso bamboo forests under extensive and intensive management practices.A1-year in-situ microcosm experiment was conducted to quantify the RScomponents in Moso bamboo forests under the two management practices using mesh screens of varying *** results showed that the total RSand its components exhibited similar seasonal variability between the two management *** with extensive management,intensive management significantly increased cumulative respiration from mycorrhizal fungi by 36.73%,while decreased cumulative respiration from free-living soil microorganisms by 8.97%.Moreover,the abundance of arbuscular mycorrhizal fungi(AMF)increased by 43.38%,but bacterial and fungal abundances decreased by 21.65%and 33.30%,respectively,under intensive *** management practices significantly changed the bacterial community composition,which could be mainly explained by soil pH and available *** fungi and intensive management affected the interrelationships between bacterial *** equation modeling indicated that intensive management changed the cumulative RSby elevating AMF abundance and lowering bacterial *** concluded that intensive management reduced the microbial respiration-derived C loss,but increased mycorrhizal respiration-derived C loss.

关键词： arbuscular mycorrhizal fungi extensive management microbial co-occurrence network root respiration soil organic C soil respiration structural equation model

Emerging tropane alkaloids:Global development and potential health threats

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Food Quality and Safety 2024年第1期8卷 12-26页

作者： Zile Wang Shiqi chen Pimiao Zheng Zhenhui Ren Huixia Zhang Jing Zhang Bing shao Congming Wu Haiyang Jiang Department of Veterinary Pharmacology and Toxicology Beijing Key Laboratory of Detection Technology for Animal-Derived Food SafetyBeijing Laboratory for Food Quality and SafetyNational Key Laboratory of Veterinary Public Health and SafetyCollege of Veterinary MedicineChina Agricultural UniversityBeijingChina. College of Veterinary Medicine Shandong Agricultural UniversityTaianChina. Tianjin Key Laboratory of Agricultural Animal Breeding and Healthy Husbandry College of Animal Science and Veterinary MedicineTianjin Agricultural UniversityTianjinChina Beijing Key Laboratory of Diagnostic and Traceability Technologies for Food Poisoning Beijing Center for Disease Prevention and ControlBeijingChina.

Tropane alkaloids(TAs)are a kind of plant secondary metabolite that mainly originate from *** have potent anticholinergic activity,and are well-known anticholinergic drugs,but have also been reported as plant *** studies have been conducted on TAs,but no scientometric research has been *** study aimed to expound the knowledge network and development of the feld of TAs and predict the emerging development topics based on *** particular,this research combined VOSviewer and CiteSpace for visualization and covered 1,298 related scientifc publications(1953–2022).The research on TAs is rapidly developing,with the participation of 86 countries,1,129 research institutions,and 4,087 ***,the University of Geneva,and *** are the most productive country,institution,and researcher,***,the main research topics on TAs include biosynthesis,in vitro synthesis,chemical synthesis,and determination *** 2018,the monitoring of TAs in food related to human health has shown citation burst characteristics,which is considered an emerging development trend in the *** fndings of this study will enable researchers to quickly tap into the knowledge background/structure of TAs from massive data to provide a reference for further research.

关键词： Tropane alkaloids bibliometrics biosynthesis in vitro synthesis chemical synthesis determination contamination food safety

Endogenous Candida albicans endophthalmitis in a patient with chronic renal failure on hemodialysis

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 979-981页

作者： Meng-Ya Liu Zhi-Fan chen Hao-sheng Liu Qian-Li Meng Department of Ophthalmology Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou 510080Guangdong ProvinceChina The Fourth Affiliated Hospital of Guangzhou Medical University Guangzhou 511400Guangdong ProvinceChina

Dear Editor,We report a rare case of endogenous endophthalmitis caused by Candida albicans in a patient with chronic renal failure concomitant hemodialysis.A 71-year-old man with a history of hypertension and 2-year chronic renal failure on hemodialysis via a native arteriovenous fistula(AVF)was presented to the local hospital due to fever 3wk *** pathogens were detected through blood culture on admission,and his fever gradually subsided with intravenous ceftriaxone *** a week of fever,he experienced progressive blurred vision in both eyes,accompanied by pain and *** magnetic resonance imaging(MRI)of the brain revealed *** had not undergone any previous eye surgeries or trauma.

关键词： hemodialysis albicans fever