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World Journal of Clinical Cases 2021年第16期9卷 3919-3926页

作者： shao-Kui nan Hai-Feng Li Dong zhang Jian-Ning Lin Li-Sheng Hou Department of Orthopedic Surgery The Sixth Medical Center of PLA General HospitalBeijing 100048China

BACKGROUND Open reduction and internal fixation(ORIF)is the traditional surgical treatment for patellar fractures,and unicompartmental knee arthroplasty(UKA),especially Oxford UKA,has been increasingly used in patients with medial knee osteoarthritis(OA).However,the process of choosing treatment for patients with both patellar fractures and anteromedial knee OA remains *** present the case of a patient with a patellar fracture and anteromedial *** SUMMARY We present the case of a 72-year-old woman with a history of bilateral medial compartment OA of the knees and a right Oxford *** also experienced a recent left patellar *** and Oxford UKA were performed in a single *** patient showed excellent postoperative clinical *** ORIF and Oxford UKA can be performed simultaneously for patients with patellar fracture and anteromedial OA on the same knee.

关键词： Patellar fracture Anteromedial osteoarthritis Open reduction and internal fixation Unicompartmental knee arthroplasty Elderly patient Case report

Internal dynamics of magma ocean and its linkage to atmospheres

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Acta Geochimica 2022年第4期41卷 568-591页

作者： Yizhuo zhang nan zhang Meng Tian Key Laboratory of Orogenic Belts and Crustal Evolution School of Earth and Space SciencesPeking UniversityBeijing100871China Earth Dynamics Research Group School of Earth and Planetary SciencesCurtin UniversityBentley6102WAAustralia Center for Space and Habitability Universität BernGesellschaftsstrasse 63012BernSwitzerland

Geological and astronomical observations on the‘‘lava world’’of the rocky planet,with additional theoretical interpretation of Moon’s crustal formation,bring up to the occurrence of the magma ocean and lava ponds,which inherits accretion energy of rocky planetesimal and evolves with subsequent energy *** or global oceans of silicate melt could be a widespread lava phase after rocky planet accretion as well as large impact and could persist on planets on orbits around other stars for various time *** processes of magma ocean formation and solidification change the phases,cause element segregations,and strongly affect the earliest compositional differentiation and volatile content of the terrestrial *** form the starting point for cooling to mildly habitable conditions and for the onset of thermally driven solid-state mantle *** formation and crystallization of magma oceans also influence the assembly of a core,the origin of a crust,initiation of tectonics,and formation of an *** is inevitable to investigate the magma ocean dynamics of such an early period of Earth *** review focuses on the internal dynamics of magma oceans after planetesimal accretion and planetary formation including turbulence,particle motion,and solid-state convection,which determine the associated processes of cooling,crystallization,and convection of magma *** differentiation is discussed *** thermodynamics of equilibration between a magma ocean and an overlying,outgassed atmosphere is also discussed,highlighting the need for more data on volatile solubility in silicate *** effect of coupling between magma ocean and solid-state mantle convection is also discussed.

关键词： Magma ocean Early atmosphere Internal dynamics

Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology,cognition,and behavior in APP/PS1 mice

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Neural Regeneration Research 2025年第2期20卷 533-547页

作者： Yanli zhang Tian Li Jie Miao Zhina zhang Mingxuan Yang Zhuoran Wang Bo Yang Jiawei zhang Haiting Li Qiang Su Junhong Guo Department of Neurology First Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Neurology Sixth Hospital of Shanxi Medical University(General Hospital of Tisco)TaiyuanShanxi ProvinceChina Department of Physiology Key Laboratory of Cellular PhysiologyMinistry of EducationShanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Hernia and Abdominal Wall Surgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Laboratory Medicine of Fenyang College Shanxi Medical UniversityFenyangShanxi ProvinceChina

In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial ***,the functional role of GGT5 in the development of Alzheimer’s disease remains *** study aimed to explore the effect of GGT5 on cognitive function and brain pathology in an APP/PS1 mouse model of Alzheimer’s disease,as well as the underlying *** observed a significant reduction in GGT5 expression in two in vitro models of Alzheimer’s disease(Aβ_(1-42)-treated hCMEC/D3 and bEnd.3 cells),as well as in the APP/PS1 mouse ***,injection of APP/PS1 mice with an adeno-associated virus encoding GGT5 enhanced hippocampal synaptic plasticity and mitigated cognitive ***,increasing GGT5 expression in cerebrovascular endothelial cells reduced levels of both soluble and insoluble amyloid-βin the brains of APP/PS1 *** effect may be attributable to inhibition of the expression ofβ-site APP cleaving enzyme 1,which is mediated by nuclear factor-kappa *** findings demonstrate that GGT5 expression in cerebrovascular endothelial cells is inversely associated with Alzheimer’s disease pathogenesis,and that GGT5 upregulation mitigates cognitive deficits in APP/PS1 *** findings suggest that GGT5 expression in cerebrovascular endothelial cells is a potential therapeutic target and biomarker for Alzheimer’s disease.

关键词： Alzheimer’s disease amyloid-β APP/PS1 mice cerebrovascular endothelial cells cognitive deficits gamma-glutamyl transferase 5 neurovascular unit nuclear factor‐kappa B synaptic plasticity β-site APP cleaving enzyme 1

An effective method to determine bedding system insulation based on measured data

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Building Simulation 2023年第1期16卷 121-132页

作者： nan zhang Bin Cao Yingxin Zhu Department of Building Science School of ArchitectureTsinghua UniversityBeijing 100084China Beijing Key Laboratory of Indoor Air Quality Evaluation and Control(Tsinghua University) Beijing 100084China Key Laboratory of Eco Planning&Green Building Ministry of Education(Tsinghua University)Beijing 100084China

The thermal environment is an essential factor that affects sleep *** many circumstances,the bed microenvironment is more important than the ambient environment because of the large covered area of the human body and the close contact between the bedding system and the human *** main objective of this research is to establish an effective method to determine bedding system insulation.A thermal manikin was used in the measurement of bedding system *** different types of quilts,which were filled with cotton,polyester and duvet respectively,were chosen to be *** total ten different quilts with different materials and weights were involved in the *** regular arrangements of covers were chosen with coverage rates of 94.1%,85.9%,70.6%,and 54.4%to test.A total of 64 bedding systems were tested to build an effective method to determine the bedding system *** the basis of test data,the change of bedding system insulation with coverage was found to be *** fitting was applied to establish an insulation evaluation method for bedding system *** addition,the effects of quilt cover and sleepwear on bedding system insulation were discussed and thermal insulation increment caused by quilt cover and sleepwear were *** relationships between neutral indoor temperature and weight per unit area of the quilt for different coverage rates have been quantified based on existing subject *** research provides an effective method to determine bedding system insulation,which can be widely used in thermal comfort research and HVAC system design.

关键词： sleep environment bedding system thermal insulation thermal comfort

Spin logic operations based on magnetization switching by asymmetric spin current

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Science China(Information Sciences) 2022年第2期65卷 181-187页

作者： Yucai LI nan zhang Kaiyou WANG State Key Laboratory of Superlattices and Microstructures Institute of Semiconductors Chinese Academy of Sciences College of Materials Science and Opto-Electronic Technology University of Chinese Academy of Sciences Beijing Academy of Quantum Information Sciences

Spintronic devices based on spin orbit torques(SOT) exhibit advantages in low power consumption, high speed, reconfigurability, and high endurance, which offers the prospect of in-memory computing based on spin logic devices. By designing a local spin current gradient, the magnetization can be switched deterministically by asymmetric spin currents without external magnetic field using micromagnetic simulations, where an additional out of plane effective field can be generated by the spin gradient. Through capping half of the Pt/Co/Pt SOT devices with Pt strip, we demonstrate the field-free deterministic currentinduced magnetization switching experimentally. Finally, we design AND, nanD, OR, and NOR Boolean logic gates based on these devices, which could be used as building blocks for programmable and stateful logic operations.

关键词： spin orbit torque spin currents spin current gradient magnetization switching spin logic

Structural design and model fabrication of cable-rib tensioned deployable parabolic cylindrical antenna

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Chinese Journal of Aeronautics 2023年第8期36卷 229-246页

作者： Shunji zhang Baoyan DUAN Shuxin zhang nan WANG Shaanxi Key Laboratory of Space Solar Power Station System Xi’an 710071China School of Electromechanical Engineering Xidian UniversityXi’an 710071China Aerospace Information Research Institute Chinese Academy of SciencesBeijing 100101 China

Deployable mechanisms with light weight and high storage ratio have received considerable attention for space applications. To meet the requirements of space missions, a parabolic cylindrical deployable antenna based on cable-rib tension structures is proposed and verified by a physical prototype. The parabolic cylindrical antenna adopts simple parallel four-bar mechanisms to construct the basic deployable unit, and the cylindrical direction dimension can be easily extended by modularization, which has obvious advantages in storage ratio and area density. Considering the complexity of the entire antenna structure design, including cable networks and flexible trusses, the form-finding design optimization model of a parabolic cylindrical antenna is established using the force density sensitivity method, and then the kinematics analysis of the deployable mechanism is carried out. Finally, a single-module prototype with a deployable diameter of 4 m × 2 m was designed and fabricated. The results of the ground deployment process test and surface accuracy measurements show that the antenna has good feasibility and practicability.

关键词： Form-finding design Kinematic analysis Mechanism design Paraboliccylindrical antenna Principle prototype

掺杂对TiC_(2)纳米片析氢反应的第一性原理研究

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原子与分子物理学报 2025年第3期42卷 29-34页

作者：孙楠楠赵翠莲潘美玲赵志超张宇河北水利电力学院基础部沧州061000 河北省数据中心相变热管理技术创新中心沧州061000

过渡金属二碳族化物单层作为一种廉价而丰富的材料,在制氢催化剂方面的应用越来越受到人们的关注.在这项工作中,基于第一性原理计算研究了掺杂二碳化钛单层的析氢还原.我们发现掺杂元素和浓度对单分子膜的催化能力有强烈的影响.结果表明... 详细信息

过渡金属二碳族化物单层作为一种廉价而丰富的材料,在制氢催化剂方面的应用越来越受到人们的关注.在这项工作中,基于第一性原理计算研究了掺杂二碳化钛单层的析氢还原.我们发现掺杂元素和浓度对单分子膜的催化能力有强烈的影响.结果表明,在高氢覆盖率内,O和V掺杂能有效的降低氢吸附的吉布斯自由能.低密度掺杂可以提高催化能力.我们进一步研究表明,由于V原子在二碳化钛(TiC_(2))单层中具有最低的负形成能,因此比其他过渡金属原子更容易取代Ti原子.期望掺钒TiC_(2)单分子膜能以更高的效率应用于水电解.

关键词：密度泛函理论 TiC_(2)单层片覆盖率掺杂

Sintering behavior of alumina whisker reinforced zirconia ceramics in hot oscillatory pressing

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Journal of Advanced Ceramics 2022年第6期11卷 893-900页

作者： Hongtian HE Rui ZHAO Hongyi TIAN Gang shao Hailong WANG Bingbing FAN Hongxia LU Hongliang XU Rui zhang Li-nan AN School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001China School of Materials Science and Engineering Luoyang Institute of Science and TechnologyLuoyang 471023China School of Mechanical Engineering Dongguan University of TechnologyDongguan 523808China

Alumina whisker reinforced zirconia ceramic composite was prepared by both hot oscillatory pressing(HOP)and conventional hot pressing(HP).The results show that compared with HP,HOP can significantly increase the final density and densification rate of the *** of densification kinetics reveals that the predominant densification mechanism transits from grain boundary sliding in the beginning to the diffusion in the later *** main effect of the oscillating pressure is to increase the densification rate in the process of grain boundary *** current study suggests that HOP is a promising technique for densifying whisker reinforced ceramics.

关键词： hot oscillatory pressing(HOP) densification behavior grain boundary sliding whisker reinforced ceramic composite

Synthesis toward the Lindenane-type Sesquiterpenoid Monomer of Chlorahololide A

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Chinese Journal of Chemistry 2013年第1期31卷 84-92页

作者： Haizhen zhang Fajun nan Chinese National Center for Drug Screening State Key Laboratory of Drug Research Shanghai Institute of Mate- ria Medica Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai 201203 China

An investigation toward the synthesis of the lindenane-type sesquiterpenoid monomer of Chlorahololide A using a Yamamoto rearrangement, intramolecular cyclopropanation reaction, 1,3-dipolar cyclization, and an intra- molecular Heck reaction gave the pivotal intermediate 20. This gives a practical synthetic route that could generate further natural products of the Chloranthaceae family.

关键词： lindenane-type sesquiterpenoid intramolecular Heck reaction Julia-Kocienski methylenation

Can imaginarity be broadcast via real operations?

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Communications in Theoretical Physics 2024年第11期76卷 66-75页

作者： Linshuai zhang nan Li Academy of Mathematics and Systems Science University of Chinese Academy of SciencesBeijing 100190China School of Mathematical Sciences University of Chinese Academy of SciencesBeijing 100049China

Imaginarity has proven to be a valuable resource in various quantum information processing tasks.A natural question arises:can the imaginarity of quantum states be broadcast via real operations?In this work,we present explicit structures for nonreal states whose imaginarity can be broadcast and *** is,for a nonreal state,its imaginarity can be cloned if and only if it is a direct sum of several maximally imaginary states under orthogonal transformation,and its imaginarity can be broadcast if and only if it is a direct sum of a real state and some nonreal qubit states which are mixtures of two orthogonal maximally imaginary states under orthogonal *** particular,we show that for a nonreal pure state,its imaginarity cannot be broadcast unless it is a maximally imaginary ***,we derive a trade-off relation on the imaginarity broadcasting of pure states in terms of the measure of irreversibility of quantum states concerning real operations and the geometric measure of *** addition,we demonstrate that any faithful measure of imaginarity is not superadditive.

关键词： imaginarity broadcasting cloning real operations