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1-Imino Nitroxide Pyrene, a Burst-type H^(+) Fluorescent Switch

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Chinese Chemical Letters 2005年第8期16卷 1125-1128页

作者： Jun LI Hong Mei WANG hui Min ma De Qing ZHANG shao Xiang XIONG Center for Molecular Sciences Institute of Chemistry Chinese Academy of Sciences Beijing 100080

1-Imino nitroxide pyrene 1 has been characterized as a H^＋ fluorescent switch. The effects of various interfering species, solvents and the irradiation of ultraviolet light on the fluorescence intensity of 1 are also investigated. 1 fluoresces weakly in the 85% ethanol media containing no more than 4.5x10-5 mol/L of H^＋（HCI）, but can produce a burst increase of about 4 times in the fluorescence intensity when the concentration of H＋ is increased to or over 4.9×10^-5mol/L. The extremely sharp response of 1 to H＋ occurs only within such a narrow concentration range. Moreover, the decrease of H^＋ concentration through adding sodium hydroxide causes the fluorescence quenching, suggesting that 1 may serve as a fluorescent switch for monitoring the concentration change of H＋ around the point of 4.5×10^-5 mol/L.

关键词： Fluorescent switch l-imino nitroxide pyrene H^+

Human induced pluripotent stem cell-derived therapies for regeneration after central nervous system injury

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Neural Regeneration Research 2025年第11期20卷 3063-3075页

作者： Stephen Vidman Yee Hang Ethan ma Nolan Fullenkamp Giles W.Plant Department of Neuroscience Ohio State UniversityColumbusOHUSA

In recent years,the progression of stem cell therapies has shown great promise in advancing the nascent field of regenerative *** the non-regenerative nature of the mature central nervous system,the concept that“blank”cells could be reprogrammed and functionally integrated into host neural networks remained *** work has also demonstrated the ability of such cells to stimulate intrinsic growth programs in post-mitotic cells,such as *** embryonic stem cells demonstrated great potential in treating central nervous system pathologies,ethical and technical concerns *** barriers,along with the clear necessity for this type of treatment,ultimately prompted the advent of induced pluripotent stem *** advantage of pluripotent cells in central nervous system regeneration is multifaceted,permitting differentiation into neural stem cells,neural progenitor cells,glia,and various neuronal *** precise spatiotemporal application of extrinsic growth factors in vitro,in addition to microenvironmental signaling in vivo,influences the efficiency of this directed *** the pluri-or multipotency of these cells is appealing,it also poses the risk of unregulated differentiation and teratoma *** of the neuroectodermal lineage,such as neuronal subpopulations and glia,have been explored with varying degrees of *** the risk of cancer or teratoma formation is greatly reduced,each subpopulation varies in effectiveness and is influenced by a myriad of factors,such as the timing of the transplant,pathology type,and the ratio of accompanying progenitor ***,successful transplantation requires innovative approaches to develop delivery vectors that can mitigate cell death and support ***,host immune responses to allogeneic grafts must be thoroughly characterized and further developed to reduce the need for *** to a clinical setting wi

关键词： axon regeneration central nervous system regeneration induced pluripotent stem cells neurotrauma regenerative medicine spinal cord injury stem cell therapy

Morphology engineering of ZnO micro/nanostructures under mild conditions for optoelectronic application

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International Journal of Minerals,Metallurgy and materials 2025年第2期32卷 498-503页

作者： Liang Chu Haoyu Shen Hudie Wei Hongyu Chen Guoqiang ma Wensheng Yan Institute of Carbon Neutrality and New Energy&School of Electronics and Information Hangzhou Dianzi UniversityHangzhou 310018China School of Applied Physics and materials Wuyi UniversityJiangmen 529020China

Zinc oxide(ZnO)serves as a crucial functional semiconductor with a wide direct bandgap of approximately 3.37 *** reaction is commonly used in the synthesis of ZnO micro/nanostructures,given its low cost,simplicity,and easy ***,ZnO morphology engineering has become desirable through the alteration of minor conditions in the reaction process,particularly at room *** this work,ZnO micro/nanostructures were synthesized in a solution by varying the amounts of the ammonia added at low temperatures(including room temperature).The formation of Zn^(2+)complexes by ammonia in the precursor regulated the reaction rate of the morphology engineering of ZnO,which resulted in various structures,such as nanoparticles,nanosheets,microflowers,and single ***,the obtained ZnO was used in the optoelectronic application of ultraviolet detectors.

关键词： morphology engineering low temperature ZnO nanosheets microflowers ultraviolet detector

Fabrication and properties of ZAO powder,sputtering target materials and the related films

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Journal of University of Science and Technology Beijing 2006年第4期13卷 346-349页

作者： Wei shao Ruixin ma Bin Liu Metallurgical and Ecological Engineering School University of Science and Technology Beijing Beijing 100083 China

Aluminum-doped zinc oxide （ZnO：Al）, abbreviated as ZAO, is a novel and widely used transparent conductive material. The ZAO powder was synthesized by chemical coprecipitation. The ZAO ceramic sputtering target materials were fabricated by sintering in air, and ZAO transparent conductive films were prepared by RF magnetron sputtering on glass substrates. XRD proved that such films had an orientation of （002） crystal panel paralleled to the surface of the glass substrate. The average transmittance of the films in the visible region exceeded 80%.

关键词： transparent conductive film Al-doped zinc oxide chemical coprecipitation sputtering target materials

Landslide Susceptibility mapping in Terms of the Slope-Unit or Raster-Unit,Which is Better?

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Journal of Earth Science 2023年第2期34卷 386-397页

作者： Siyuan ma Xiaoyi shao Chong Xu Key Laboratory of Seismic and Volcanic Hazards Institute of GeologyChina Earthquake AdministrationBeijing 100029China National Institute of Natural Hazards Ministry of Emergency Management of ChinaBeijing 100085China Key Laboratory of Compound and Chained Natural Hazards Dynamics Ministry of Emergency Management of ChinaBeijing 100085China

Choice of appropriate mapping units is important in landslide susceptibility mapping(LSM).There are various possible units for this choice,while it remains unclear which one is better in *** purpose of this study is to make a quantitative comparison of two commonly-used units:slope-unit(SU)and raster-unit(RU)based on the landslides triggered by the 2013 Minxian,Gansu,China Mw5.9 *** landslide influencing factors were considered in this *** each type of mapping units,the 70%samples were randomly selected and trained 20 times on the LR model,yielding 20 susceptibility maps,and the remaining 30%samples were tested for the accuracy of the modeling *** metrics,including the mean probability,model uncertainty,and model prediction skills,were used to evaluate the quality of the susceptibility *** results show that the resultant probability maps using two mapping units can largely predict the distribution of actual landslides,on which the high susceptibility area corresponds to the landslide-prone *** AUC(area under curve)values,ranging from 0.8 to 0.86,show that the prediction ability of two mapping units is roughly the *** comparing with the RU,the use of SU can lower the model uncertainties caused by the variation of training *** converted the RU-based assessment results into SU-based *** results show that two assessment results are well fitted with good linear relationship,which implies that it is feasible to convert the RU-based landslide susceptibility mapping into the SU-based *** analysis indicates that compared with the RU,the SU cannot improve the performance and accuracy of seismic landslide susceptibility mapping.

关键词： earthquake-triggered landslides Minxian earthquake logistic regression(LR)model landslide susceptibility mapping unit engineering geology

MET receptor tyrosine kinase promotes the generation of functional synapses in adult cortical circuits

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Neural Regeneration Research 2025年第5期20卷 1431-1444页

作者： Yuehua Cui Xiaokuang ma Jing Wei Chang Chen Neha Shakir Hitesch Guirram Zhiyu Dai Trent Anderson Deveroux Ferguson Shenfeng Qiu Basic Medical Sciences University of Arizona College of Medicine-PhoenixPhoenixAZUSA Department of Medicine University of Arizona College of Medicine-PhoenixPhoenixAZUSA

Loss of synapse and functional connectivity in brain circuits is associated with aging and neurodegeneration,however,few molecular mechanisms are known to intrinsically promote synaptogenesis or enhance synapse *** have previously shown that MET receptor tyrosine kinase in the developing cortical circuits promotes dendritic growth and dendritic spine *** investigate whether enhancing MET in adult cortex has synapse regenerating potential,we created a knockin mouse line,in which the human MET gene expression and signaling can be turned on in adult(10–12 months)cortical neurons through doxycycline-containing *** found that similar to the developing brain,turning on MET signaling in the adult cortex activates small GTPases and increases spine density in prefrontal projection *** findings are further corroborated by increased synaptic activity and transient generation of immature silent *** MET signaling resulted in an increasedα-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/N-methyl-Daspartate(AMPA/NMDA)receptor current ratio,indicative of enhanced synaptic function and *** data reveal that enhancing MET signaling could be an interventional approach to promote synaptogenesis and preserve functional connectivity in the adult *** findings may have implications for regenerative therapy in aging and neurodegeneration conditions.

关键词： aging circuit connectivity cortical circuits molecular mechanisms neural regeneration neurodegeneration synapses

A modified wake model in bubble-induced three-phase inverse fluidized bed(BIFB)

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Particuology 2022年第6期20卷 133-138页

作者： Keying ma Xiliang Sun Yuanyuan shao Jesse Zhu Collaborative Innovation Center of Chemical Science and Engineering(Tianjin) School of Chemical Engineering of TechnologyTianjin UniversityTianjin 300072China Department of Chemical&Biochemical Engineering The University of Western OntarioLondonOntarioN6A 3K7Canada

A modified wake model was proposed for the newly developed bubble-induced three-phase inverse fluidized bed(BIFB),by combining the generalized wake model and the gas-perturbed liquid *** the basis of the modified wake model,the solids and liquid holdups and the complete fluidization gas velocity in BIFB system have been successfully predicted with two established *** predictions achieved very good agreements with the experimental data.

关键词： Generalized wake model Solids holdup Liquid holdup Complete fluidization gas velocity

Highly sensitive glucose sensor based on hierarchical CuO

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Science China(Technological Sciences) 2021年第1期64卷 65-70页

作者： CHEN Fang shao Bo ZHAI Wei ma XiaoYan MOE Key Laboratory of material Physics and Chemistry under Extraordinary Conditions Northwestern Polytechnical UniversityXi’an 710129China

The fabrication of high performance CuO based glucose sensors remains a great challenge due to the "trade-off effect" between sensitivity and linear range. In this study, a hierarchical CuO nanostructure with a great number of firecracker-shaped nanorods along the ligament and three-dimensional interconnected nanoporous is obtained by dealloying and post oxidation process of Al-33.3 wt% Cu eutectic alloy ribbons. Because of the precise structural design, not only the number of active sites for glucose electro-oxidation is significantly increased but also the glucose diffusion under high concentration is greatly accelerated, leading to a high sensitivity of 1.18 ma cm^(-2) mM^(-1) and a wider linear range up to 5.53 mM for glucose detection. This work provides a potential approach to design hierarchical nanostructure for other metal oxides with desirable properties for electrocatalytic applications.

关键词： hierarchical CuO nanostructure dealloying glucose sensor highly sensitive

Hydrodynamics of a bubble-induced inverse fluidized bed reactor with a nanobubble tray

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Particuology 2023年第2期73卷 8-16页

作者： Yicheng Deng Keying ma Yuanyuan shao Jesse Zhu School of Chemical Engineering and Technology Tianjin UniversityTianjin300072China Department of Chemical and Biochemical Engineering The University of Western OntarioLondonOntarioN6A 3K7Canada Institute of shaoxing Tianjin UniversityZhejiang312300China

This paper reports on the hydrodynamics of a bubble-induced inverse fluidized bed reactor,using a nanobubble tray gas distributor,where solid particles are fluidized only by an upward gas *** the gas velocity,the fixed layer of particles initially packed at the top of the liquid starts to move downwards,due to the rise of bubbles in this system,and then gradually expands downwards until fully *** axial local pressure drops and standard deviation were examined to delineate the flow regime comprehensively under different superficial gas *** flow regimes(fixed bed regime,initial fluidization regime,expanded regime,and post-homogeneous regime)were observed and three transitional gas velocities(the initial fluidization velocity,minimum fluidization velocity,and homogeneous fluidization velocity)were identified to demarcate the flow *** correlations were developed for the three transitional *** the fine bubbles generated from the nanobubble tray gas distributor are well distributed in the entire column,the bed expansion process of the particles is relatively steady.

关键词： Bubble-induced Inverse fluidized bed Pressure drop Flow regime Bed expansion ratio Standard deviation