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不同宿主来源产气荚膜梭菌生物被膜形成前后药物敏感性分析

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动物医学进展 2025年第1期46卷 38-42页

作者：吴莹邵长军刘文华青岛农业大学动物医学院山东青岛266109 烟台市农科院山东烟台264200

为了检测5株不同宿主来源产气荚膜梭菌形成生物被膜能力及其对抗菌药物的敏感性差异,首先用纸片扩散法药敏试验测定5株不同来源的产气荚膜梭菌对7种抗菌药物的敏感性;筛选高敏药物测定各菌株的最小抑菌浓度(MIC);利用结晶紫染色法检测... 详细信息

为了检测5株不同宿主来源产气荚膜梭菌形成生物被膜能力及其对抗菌药物的敏感性差异,首先用纸片扩散法药敏试验测定5株不同来源的产气荚膜梭菌对7种抗菌药物的敏感性;筛选高敏药物测定各菌株的最小抑菌浓度(MIC);利用结晶紫染色法检测不同来源产气荚膜梭菌生物被膜形成能力和高敏药物对生物被膜的抑制和清除能力。药敏结果显示,5株不同宿主来源产气荚膜梭菌均对氨苄西林高度敏感,对其余6种抗菌药物有不同程度耐药;氨苄西林对不同菌株的MIC值在0.031~2.000μg/mL之间;所有菌株均能生成生物被膜,但生物被膜生成能力有差异;不同菌株在各自4、2、1 MIC下生物被膜的生成受到不同程度抑制,而亚抑菌浓度的氨苄西林能刺激生物被膜的生成,氨苄西林对已经生成的生物被膜不能完全清除。结果表明,不同来源产气荚膜梭菌形成生物被膜前后对药物敏感性不同,可为产气荚膜梭菌的临床用药选择及使用剂量提供一定的参考依据。

关键词：产气荚膜梭菌生物被膜最小抑菌浓度耐药性

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NES cell

Applied Mathematics and Mechanics(English Edition) 2022年第12期43卷 1793-1804页

作者： Hu DING Yufei shao Shanghai Key Laboratory of Mechanics in Energy Engineering School of Mechanics and Engineering ScienceShanghai UniversityShanghai200072China

A broadband adaptive vibration control strategy with high reliability and flexible versatility is *** high vibration damping performance of nonlinear energy sink(NES)has attracted ***,targeted energy transfer may cause severe vibration of ***,it is difficult to realize pure nonlinear stiffness without the linear *** a result,the reliability of NES is not *** low reliability of NES has hindered its application in *** addition,the performance of NES depends on its mass ratio of the primary system,and NES lacks versatility for different vibration ***,this paper proposes the concept of NES *** advantages of the adaptive vibration control of NES are applied to cellular *** applying a large number of NES cells in parallel,the reliability of NES and its versatility to complex vibration structures are *** elastic beam is used as the primary vibration structure,and a limited NES is used as the *** relationship between the vibration suppression effect of NES cells and the number of NES cell is *** addition,the effect of the distribution of NES cells on the multi-mode resonance suppression of the beam is also *** summary,the mode of the primary structure can be efficiently controlled by a large number of lightweight NES ***,the lightweight NES cell is flexible for vibration control of complex *** addition,it improves the reliability of NES ***,the distributed application of NES cells proposed in this paper is a valuable vibration suppression strategy.

关键词： vibration nonlinear energy sink(NES) NES cell vibration control clamped beam harmonic balance method(HBM)

Sampling Dependent Stability Results for Aperiodic Sampled-Data Systems

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Journal of Systems Science & Complexity 2021年第2期34卷 588-601页

作者： shao Hanyong YUAN Guangxia The Institute of Automation Qufu Normal UniversityRizhao 276826China

This paper investigates sampling dependent stability for aperiodic sampled-data systems by employing a Lyapunov-like functional that is time-dependent,and not imposed to be definite *** on the system information on the sampling interval wholly rather than partly,a new Lyapunovlike functional is constructed,which extends existing ones by introducing the integral of the system state and the cross terms among this integral and the sampled *** take advantage of the integral of the system state,integral equations of the sampled-data system are explored when estimating the derivative of the extended *** the Lyapunov-like functional theory,a new sampling dependent stability result is obtained for sampled-data systems without ***,the stability result is applied to sampled-data systems with polytopic uncertainties and a robust stability result is *** last,numerical examples are given to illustrate that the stability results improve over some existing ones.

关键词： Asymptotic stability Lyapunov-like functional polytopic uncertainties sampled-data systems

Challenges and countermeasures of urban water systems against climate change:a perspective from China

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Frontiers of Environmental Science & Engineering 2023年第12期17卷 189-195页

作者： Yisheng shao Yijian Xu China Academy of Urban Planning&Design No.5 Chegongzhuang West RoadBeijing 100044China

Urban water systems are facing various challenges against climate change,impacting cities’security and their sustainable ***,there are three major challenges:submersion risk of coastal cities as glaciers melt and sea level rises,more and severe urban flooding caused by extreme weather like intensified storm surge and heavy precipitation,and regional water resource patterns challenged by alteration of spatial distribution of *** this,two strategies including proactive adaptation and positive mitigation were proposed in this article to realize the reconstruction and optimization of urban water systems,to enhance their resilience,and eventually increase their adaptability and coping ability to climate *** proactive adaptation strategy consists of 1)construction of sponge cities to accommodate the increased regular rainfall and to balance the alterations of spatial redistribution of precipitation;2)reconstruction of excess stormwater discharge and detention system to increase capability for extreme precipitation events based on flood risk assessment under future climate change;3)deployment of forward-looking,ecological,and integrated measures to improve coastal protection capability against inundation risks caused by climate change and sea level *** positive mitigation strategy is to employ the systematic concept in planning and design and to adopt advanced applicable energy-saving technologies,processes,and management practices,aiming at reduction in flux of urban water systems,reinforcement in energy conservation and carbon reduction in both water supply systems and wastewater treatment systems,and thus a reduction of greenhouse gas emission from urban water systems.

关键词： Climate change Urban water system Resilience Adaptation Mitigation

Topologically Correct Intersection Curves of Two Trimmed Quadrics with Tolerance Control

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Journal of Systems Science & Complexity 2024年第5期37卷 2207-2239页

作者： shao Wenbing CHEN Falai Department of Mathematics University of Science and Technology of ChinaHefei 230026China

Surface/surface intersection is a fundamental problem in Compute Aided Design and Geometric Modeling since it is essential to solid modeling,numerically controlled machining,feature recognition,computer animation,*** practical applications,quadric surfaces,which are the most basic type of surfaces,are typically bounded surfaces trimmed by a sequence of *** this paper,a robust algorithm is proposed for computing the intersection curve segments of two trimmed quadrics based on the parametric representation of the intersection curves of two *** proposed algorithm guarantees correct topology and ensures that the approximation errors of the end points of the intersection curve segments are less than a given *** error control is based on an effective solution to a set of polynomial inequality system using the root isolation *** examples are presented to validate the robustness and effectiveness of the proposed algorithm.

关键词： Polynomial inequality system root isolation surface/surface intersection tolerance control trimmed quadrics

Theoretical Analysis of Crack Propagation Measurement for Brittle Materials Based on Virtual Principal Strain Field

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Acta Mechanica Solida Sinica 2022年第5期35卷 842-850页

作者： Liuning Gu Xinxing shao Department of Engineering Mechanics School of Civil EngineeringSoutheast UniversityNanjing211189China

The measurement of crack propagation is crucial for revealing the fracture mechanical properties of materials and *** on the virtual principal strain field and Steger’s algorithm,an accurate and automatic method has been proposed for measuring the geometric parameters of crack *** measured geometric parameters of crack propagation include the width,length,and tip location of each *** mechanism of the crack-induced virtual principal strain field and the effects of subset,step,and strain window size are analyzed and discussed *** effectiveness of the derived theoretical equations is verified by the simulation *** to the theoretical equations,it is determined that the distribution of the virtual principal strain field near the crack is similar to the grayscale distribution of the laser fringe image with optimized calculation *** are further conducted to validate the effectiveness of the derived *** the optimized calculation parameters,the minimum crack that can be measured is approximately 0.0362 pixel in the laboratory environment,while the measurement error of the crack width is less than 0.025 pixel for two-dimensional digital image correlation(DIC)and 0.020 pixel for three-dimensional DIC.

关键词： Crack propagation Brittle materials Digital image correlation Virtual principal strain Steger’s algorithm

Integrated　Optical　Parallel　Logic　Processor　Based　on　Birefringent　Array　Illuminator

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Chinese Journal of Lasers 1996年第3期B5卷 276-281页

作者： shao Lan LIU Liren LI Guoqiang PENG haifeng(Shanghai Institute of Opitcs and Fine Mechanics,Academia Sinica,P.O.Box 800-216, Shanghai 201800, China) Shanghai Inst of Optics and Fine Mechanics Academia Sinica Shanghai China

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关键词： birefringent array illuminator logic control package density

Work Function and Electron Affinity of Semiconductors:Doping Effect and Complication due to Fermi Level Pinning

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Energy & Environmental Materials 2021年第3期4卷 273-276页

作者： Guosheng shao State Center for International Cooperation on Designer Low-carbon and Environmental Materials Zhengzhou UniversityZhengzhou 450001China School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001China Zhengzhou Materials Genome Institute XingyangZhengzhou 450100China

Semiconductors are a major category of functional materials essential to various applications to sustain the modern *** applied materials or devices utilizing semiconductors are enabled by interfaces or junctions,such as solar cells,electronic/photonic devices,environmental sensors,and redox ***,the author provides a critical commentary on photoemission measurement of the work function and,more importantly,the electron affinity of semiconductors essential for energy band diagram of *** effort is made towards addressing complications associated with Fermi level pinning due to surficial states of doped semiconductors.

关键词： band edges electron affinity Fermi pinning ultraviolet photoelectron spectroscopy work function

On necessary and sufficient conditions for the self-normalized central limit theorem In Honor of Professor Chuanrong Lu on His 85th Birthday

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Science China Mathematics 2018年第10期61卷 1741-1748页

作者： Qiman shao Department of Statistics The Chinese University of Hong Kong

Let X_1, X_2,... be a sequence of independent random variables and S_n=sum X_1 from i=1 to n and V_n^2=sum X_1~2 from i=1 to n . When the elements of the sequence are i.i.d., it is known that the self-normalized sum S_n/V_n converges to a standard normal distribution if and only if max1≤i≤n|X_i|/V_n → 0 in probability and the mean of X_1 is zero. In this paper, sufficient conditions for the self-normalized central limit theorem are obtained for general independent random variables. It is also shown that if max1≤i≤n|X_i|/V_n → 0 in probability, then these sufficient conditions are necessary.

关键词： central limit theorem self-normalized independent random variables