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Collaborative Trajectory Planning for Stereoscopic Agricultural Multi-UAVs Driven by the Aquila Optimizer

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Computers, Materials & Continua 2025年第1期82卷 1349-1376页

作者： Xinyu Liu Longfei wang Yuxin Ma Peng shao School of Computer and Information Engineering Jiangxi Agricultural UniversityNanchang330045China

Stereoscopic agriculture,as an advanced method of agricultural production,poses new challenges for multi-task trajectory planning of unmanned aerial vehicles(UAVs).To address the need for UAVs to perform multi-task trajectory planning in stereoscopic agriculture,a multi-task trajectory planning model and algorithm(IEP-AO)that synthesizes flight safety and flight efficiency is *** on the requirements of stereoscopic agricultural geomorphological features and operational characteristics,the multi-task trajectory planning model is ensured by constructing targeted constraints at five aspects,including the path,slope,altitude,corner,energy and obstacle threat,to improve the effectiveness of the trajectory planning *** combined with the path optimization algorithm,an Aquila optimizer(IEP-AO)based on the interference-enhanced combination model is proposed,which can help UAVs to improve the trajectory search capability in complex operation space and large-scale operation tasks,and jump out of the locally optimal trajectory path region timely,to generate the optimal trajectory planning plan that can adapt to the diversity of the tasks and the flight ***,four simulated flights with different operation scales and different scene constraints were conducted under the constructed real 3Dimension scene,and the experimental results can show that the proposedmulti-task trajectory planning method canmeet themulti-task requirements in stereoscopic agriculture and improve the mission execution efficiency and agricultural production effect of UAV.

关键词： Stereoscopic agriculture unmanned aerial vehicle multi-task interference model Aquila optimizer

17β-Estradiol protects SD rat retinal neurons from light damage by activating PI3K/Akt and NF-κB signal pathways

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17β-Estradiol protects SD rat retinal neurons from light da...

Molecular Structure Tailoring of Organic Spacers for High‑Performance Ruddlesden–Popper Perovskite Solar Cells

中国生物化学与分子生物学会第十届会员代表大会暨全国学术会议

作者： Ming Shu Mo shao lan wang Hongbo Li Yan Feng Zhaoliang Zhu Baoying wang Ruochen Zhu Shuhong wang Yan Han Xiaorui Yu Department of Genetics and Molecular Biology School of MedicineXi’an Jiaotong University

Our previous studies have proved that the phosphatidylinositol-3-kinase(PI3K)/Akt signal pathway was involved in the neuroprotection of 17β-estradiol(βE2) against H2O2-induced retinal neurons apoptosis in *** aim of this study is to observe whetherβE2 can also protect retinal neurons from light damage in vivo by activating the PI3K/Akt signal *** used 180 to 230 g female SD rats exposed to persistent white light after ovariectomy 2 weeks as experimental model and used Electroretinogram (ERG),DNA ladder,TUNEL,HE staining,Western blotting and Immunofluorescence techniques to investigate the neuroprotection ofβ*** results showed that SD rats were exposed to 8000 lux white light for 12 h resulted in retinal function decrease and photoreceptor cells apoptosis, and 10-4M and 10-5MβE2 by intravitreal injection all significantly enhanced the photosensitive function of retinal by preventing neuronal *** mechanism research found that the neuroprotection ofβE2 involved in increasing the phosphorylation of Akt which was partly blocked by the pretreatment with PI3K inhibitor LY294002 for 30 min beforeβE2 *** cleaved caspase-3 as an activation form of caspase-3 was observed after light damage and the administration ofβE2 can attenuate the activation of caspase-3,while pretreatment with LY294002 can inhibit the attenuation ofβ*** results showed that NF-κB translocated from cytoplasm to nucleus afterβE2 injection,and LY294002 could also inhibit partly this *** present results indicated thatβE2 has a neuroprotective effect against light-induced photoreceptor cells apoptosis,and the PI3K/Akt pathway plays an important role in this neuroprotection,which involved in translocation of NF-κB from cytoplasm to nucleus and inhibited the activation of caspase- 3,but the detailed mechanism of theβE2 neuroprotection is being further study.

关键词： 17β-estradiol retinal light damage neuroprotection apoptosis

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Nano-Micro Letters 2025年第2期17卷 314-357页

作者： Pengyun Liu Xuejin Li Tonghui Cai Wei Xing Naitao Yang Hamidreza Arandiyan Zongping shao shaobin wang shaomin Liu School of Materials Science and Engineering State Key Laboratory of Heavy Oil ProcessingChina University of Petroleum(East China)Qingdao 266580People’s Republic of China School of Chemistry and Chemical Engineering Shandong University of TechnologyZibo 255049People’s Republic of China Centre for Applied Materials and Industrial Chemistry(CAMIC) School of ScienceRMIT UniversityMelbourneVic 3000Australia WA School of Mines:Minerals Energy and Chemical Engineering(WASM‑MECE)Curtin UniversityPerthWA 6102Australia School of Chemical Engineering The University of AdelaideAdelaideSA 5005Australia School of Engineering Great Bay UniversityDongguan 523000People’s Republic of China

Layer-structured Ruddlesden–Popper(RP)perovskites(RPPs)with decent stability have captured the imagination of the photovoltaic research community and bring hope for boosting the development of perovskite solar cell(PSC)***,two-dimensional(2D)or quasi-2D RP PSCs are encountered with some challenges of the large exciton binding energy,blocked charge transport and poor film quality,which restrict their photovoltaic ***,these issues can be readily resolved by rationally designing spacer cations of *** review mainly focuses on how to design the molecular structures of organic spacers and aims to endow RPPs with outstanding photovoltaic *** firstly elucidated the important roles of organic spacers in impacting crystallization kinetics,charge transporting ability and stability of *** we brought three aspects to attention for designing organic ***,we presented the specific molecular structure design strategies for organic spacers of RPPs aiming to improve photovoltaic performance of RP *** proposed strategies in this review will provide new avenues to develop novel organic spacers for RPPs and advance the development of RPP photovoltaic technology for future applications.

关键词： Ruddlesden-Popper perovskites Low-dimensional perovskite solar cells Organic spacers Molecular structure Design strategies

Decreased levels of phosphorylated synuclein in plasma are correlated with poststroke cognitive impairment

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Neural Regeneration Research 2025年第9期20卷 2598-2610页

作者： Yi wang Yuning Li Yakun Gu Wei Ma Yuying Guan Mengyuan Guo Qianqian shao Xunming Ji Jia Liu Department of Clinical Laboratory Beijing Bo’ai HospitalChina Rehabilitation Research CenterCapital Medical UniversityBeijingChina Beijing Institute of Brain Disorders Laboratory of Brain DisordersMinistry of Science and TechnologyCollaborative Innovation Center for Brain DisordersBeijing Advanced Innovation Center for Big Data-based Precision MedicineCapital Medical UniversityBeijingChina Department of Neurosurgery Xuanwu HospitalCapital Medical UniversityBeijingChina

Poststro ke cognitive impairment is a major secondary effect of ischemic stroke in many patients;however,few options are available for the early diagnosis and treatment of this *** aims of this study were to(1)determine the specific relationship between hypoxic andα-synuclein during the occur of poststroke cognitive impairment and(2)assess whether the serum phosphorylatedα-synuclein level can be used as a biomarker for poststro ke cognitive *** found that the phosphorylatedα-synuclein level was significantly increased and showed pathological aggregation around the cerebral infa rct area in a mouse model of ischemic *** addition,neuronalα-synuclein phosphorylation and aggregation were observed in the brain tissue of mice subjected to chronic hypoxia,suggesting that hypoxia is the underlying cause ofα-synuclein-mediated pathology in the brains of mice with ischemic *** phosphorylatedα-synuclein levels in patients with ischemic stroke were significantly lower than those in healt hy subjects,and were positively correlated with cognition levels in patients with ischemic ***,a decrease in serum high-density lipoprotein levels in stroke patie nts was significantly correlated with a decrease in phosphorylatedα-synuclein *** ischemic stroke mice did not show significant cognitive impairment or disrupted lipid metabolism 14 days after injury,some of them exhibited decreased cognitive function and reduced phosphorylatedα-synuclein *** together,our results suggest that serum phosphorylatedα-synuclein is a potential biomarker for poststroke cognitive impairment.

关键词： biomarker high-density lipoprotein ischemic stroke phosphorylatedα-synuclein poststroke cognitive impairment

High-resolution imaging through dynamic scattering media: Iterative optimization based on polarimetric characteristics

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Science China Technological Sciences 2025年第1期 82-84页

作者： Meng XIANG Kai DENG Tianyu wang Jinpeng LIU Xue DONG Teli XI Fei LIU Xiaopeng shao School of Optoelectronic Engineering Xidian University Xi'an Key Laboratory of Computational Imaging National Key Laboratory of Infrared Detection Technologies

High-resolution imaging through randomly dynamic scattered fields and highly scattered walls is an extensively sought-after capability with potential applications in various fields such as underwater imaging, biomedical imaging, and seeing through fog. Numerous methods have been proposed to unscramble object information from degraded scattered images, resulting in considerable improvements in image contrast in degraded scenarios [1].

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Single-cell omics: experimental workflow, data analyses and applications

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Science China Life Sciences 2025年第1期68卷 5-102页

作者： Fengying Sun Haoyan Li Dongqing Sun Shaliu Fu Lei Gu Xin shao Qinqin wang Xin Dong Bin Duan Feiyang Xing Jun Wu Minmin Xiao Fangqing Zhao Jing-Dong J.Han Qi Liu Xiaohui Fan Chen Li Chenfei wang Tieliu Shi Department of Clinical Laboratory the Affiliated Wuhu Hospital of East China Normal University (The Second People's Hospital of Wuhu City) Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang University Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration (Tongji University) Ministry of EducationOrthopaedic DepartmentTongji HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Frontier Science Center for Stem Cells School of Life Sciences and TechnologyTongji University Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Research Institute of Intelligent Computing Zhejiang Lab Shanghai Research Institute for Intelligent Autonomous Systems Center for Single-cell Omics School of Public HealthShanghai Jiao Tong University School of Medicine National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang University Center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal University Beijing Institutes of Life Science Chinese Academy of Sciences Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesCenter for Quantitative Biology (CQB)Peking University Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases Women's HospitalZhejiang University School of Medicine Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOE School of StatisticsEast China Normal University

Cells are the fundamental units of biological systems and exhibit unique development trajectories and molecular features. Our exploration of how the genomes orchestrate the formation and maintenance of each cell, and control the cellular phenotypes of various organismsis, is both captivating and intricate. Since the inception of the first single-cell RNA technology, technologies related to single-cell sequencing have experienced rapid advancements in recent years. These technologies have expanded horizontally to include single-cell genome, epigenome,proteome, and metabolome, while vertically, they have progressed to integrate multiple omics data and incorporate additional information such as spatial sc RNA-seq and CRISPR screening. Single-cell omics represent a groundbreaking advancement in the biomedical field,offering profound insights into the understanding of complex diseases, including cancers. Here, we comprehensively summarize recent advances in single-cell omics technologies, with a specific focus on the methodology section. This overview aims to guide researchers in selecting appropriate methods for single-cell sequencing and related data analysis.

关键词： single-cell sequencing genome epigenome proteomics metabolomics multimodal spatial transcriptomics CRISPR screening

“药肥组合”对乌药白绢病的防治效果及产量影响研究

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农药科学与管理 2017年第5期38卷 52-54,58页

作者：邵军刘刚王岚陈国强陕西省城固县植保植检站陕西城固723200 陕西省汉中市植保植检站陕西汉中723000

为了筛选乌药白绢病防病增产的最佳"药肥组合",指导大面积防治,选用24%噻呋酰胺悬浮剂等5种杀菌剂以及叶面肥金钾(N10%、P_2O_515%、K_2O_30%及微量元素)进行田间药效对比试验。结果表明,30%甲霜·恶霉灵水剂+金钾对乌药白绢病的防效达6... 详细信息

为了筛选乌药白绢病防病增产的最佳"药肥组合",指导大面积防治,选用24%噻呋酰胺悬浮剂等5种杀菌剂以及叶面肥金钾(N10%、P_2O_515%、K_2O_30%及微量元素)进行田间药效对比试验。结果表明,30%甲霜·恶霉灵水剂+金钾对乌药白绢病的防效达63.29%,无论是速效性还是持效期均优于其他供试药剂,增产幅度大,增幅达27.53%。

关键词：白绢病杀菌剂药效试验乌药

喜马拉雅山区中国西藏与尼泊尔的地质灾害灾情差异研究

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灾害学 2025年第1期40卷 187-193页

作者：兰思辰邵丽竹肖怡晴郑相宜王瑛北京师范大学环境演变与自然灾害教育部重点实验室北京100875 北京师范大学地理科学学部北京100875 应急管理部-教育部减灾与应急管理研究院北京100875

喜马拉雅山区是全球地质灾害最为多发的地区之一。其北侧的中国西藏地区与南侧的尼泊尔在地质灾害的灾情及其成因上存在显著差异。该研究选取这两个地区作为案例,对比分析了2012—2021年间的地质灾害情况。尼泊尔记录了2256次地质灾害,... 详细信息

喜马拉雅山区是全球地质灾害最为多发的地区之一。其北侧的中国西藏地区与南侧的尼泊尔在地质灾害的灾情及其成因上存在显著差异。该研究选取这两个地区作为案例,对比分析了2012—2021年间的地质灾害情况。尼泊尔记录了2256次地质灾害,远高于我国西藏地区的799次;同时,尼泊尔的人员伤亡也更为严重,两地年均每百万人的伤亡率分别为8.1人和2人;尼泊尔的年均因灾经济损失远低于西藏,两地地质灾害损失占GDP比例分别为0.006%、0.07%。尼泊尔近年来地质灾害次数的增加与道路建设密切相关,年均道路里程增加1036km,且37%的伤亡案例发生在道路沿线。研究结果表明,尼泊尔和中国在地质灾害防治措施上均有所加强,并已取得显著的减灾效果。

关键词：地质灾害灾情差异喜马拉雅中国西藏尼泊尔

E_2、P、hCG水平对药流后异常子宫出血的临床意义

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标记免疫分析与临床 2016年第12期23卷 1424-1426页

作者：张锋英邵秀兰王巧岭上海市金山区亭林医院妇产科上海201505

目的探讨雌二醇(E_2)、孕酮(P)、人绒毛膜促性腺激素(h CG)水平对药流后异常子宫出血的临床意义。方法选择2013年1月至2016年1月到我院妇产科收治的自愿要求进行药物终止妊娠的妇女500例,将药物流产后子宫出血时间≤14d作为正常组(n=250... 详细信息

目的探讨雌二醇(E_2)、孕酮(P)、人绒毛膜促性腺激素(h CG)水平对药流后异常子宫出血的临床意义。方法选择2013年1月至2016年1月到我院妇产科收治的自愿要求进行药物终止妊娠的妇女500例,将药物流产后子宫出血时间≤14d作为正常组(n=250),>14d作为异常组(n=250),选取同期我院妇产科收治的自愿要求手术流产400例妇女作为对照组。比较3组妇女不同时间点的E_2、P、h CG水平。结果 3组妇女血清E_2水平均呈上升趋势,其中异常组与正常组比较差异无统计学意义(P>0.05);异常组血清P水平显著高于对照组(P<0.05);异常组血清h CG水平显著高于对照组和正常组(P<0.05)。结论药流后异常子宫出血妇女血清的P、hCG水平均异常,与E_2无关,因此联合监测P、hCG水平有利于药物流产后异常子宫出血的预测和治疗。

关键词：雌二醇孕酮人绒毛膜促性腺激素异常子宫出血