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NSGA-II based trajectory optimization on 3D point cloud for spray painting robots

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NSGA-II based trajectory optimization on 3D point cloud for ...

Benefit of adjuvant chemoradiotherapy in patients with pathologically lymph node-positive and locally advanced gastric cancer

第40届中国控制会议

作者： Yadi zhang shanhui zhang Xin Ma School of Control Science and Engineering Shandong University

Spraying trajectory planning for complex surface has always been a challenging problem. On the basis of a spraying path generated with the 3 D point cloud slice, this paper proposes a Non-dominated Sorting Genetic Algorithm（NSGA-II） based spraying trajectory optimization method for complex surfaces. Firstly, the point cloud slicing method is used to generate the initial spraying path of complex surfaces. In particular, aiming at the possible path self-intersection problem near the high curvature region on complex surfaces, a path smoothing method based on monotone chain is proposed to eliminate invalid path loops. Then, a multi-objective NSGA-II spray trajectory optimization method is proposed to optimize spray efficiency and spray quality by improving the spray speed distribution along the spray path. Finally, the proposed approach is verified on real automotive surfaces, the results show its robustness and efficiency in solving spray trajectory planning problems on complex surfaces.

关键词： Point Cloud Slicing Spray Robot Multi-objective Trajectory Optimization NSGA-II

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Oncology and Translational Medicine 2020年第2期6卷 72-80页

作者： shanhui zhang Fei Zhou Donghai Liang Hongying Lv Hongsheng Yu Qingdao University Qingdao 266000China Department of Oncology Affiliated Hospital of Qingdao UniversityQingdao 266000China

Objective This study aimed to compare the effectiveness of adjuvant chemoradiotherapy(CRT)and adjuvant chemotherapy(ChT)for T3–4/N+gastric cancer(GC)following D2/R0 dissection,and identify the specific subgroups that could benefit from adjuvant *** All eligible patients were divided into the CRT group and ChT *** assessed the survival outcomes and patterns of recurrence for each group,and determined the prognostic factors for survival by performing Cox proportional risk regression *** A total of 192 gastric cancer patients were included in the *** estimated 3-year and 5-year disease-free survival(DFS)probabilities in the CRT and ChT groups were 52.9%vs.36.7%(P=0.024)and 41.2%vs.31.1%(P=0.148),respectively,and the estimated 3-year and 5-year overall survival(OS)probabilities were 82.4%vs.70.0%(P=0.044)and 52.0%vs.35.6%(P=0.022).Patients in the CRT group had a lower risk of locoregional recurrence than those in the ChT group(20.6%vs.34.4%;P=0.031).The subset analyses revealed that patients with stage N1–2 disease were more likely to benefit from adjuvant CRT than from adjuvant ChT(DFS:53.1%vs.36.4%;P=0.039;OS:53.1%vs.38.6%;P=0.036).Conclusion For locally advanced gastric cancer patients with LN+,adjuvant CRT showed superior survival benefits compared with adjuvant ChT *** with N1–2 achieved better survival from adjuvant CRT.

关键词： locally advanced gastric cancer adjuvant chemoradiotherapy adjuvant radiotherapy lymph node-positive survival and prognosis

The role of miR-7 as a potential switch in the mouse hypothalamus-pituitary-ovary axis through regulation of gonadotropins

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The role of miR-7 as a potential switch in the mouse hypotha...

PROCESS-ORIENTED PRODUCT KNOWLEDGE MANAGEMENT

第十四届全国免疫学学术大会

作者： Jing He Shirong Xu Zengjun Ji Youhong Sun Bingyan Cai shanhui zhang Pingping Wang Jiangsu Agri-animal Husbandry Vocational College

The hypothalamus-pituitary-ovary(HPO) axis plays fundamental roles in female neuroendocrinology and reproduction. Pituitary gonadotropins are located in the center of this axis. Previous investigation suggested that miR-7 is closely linked with gonadotropins. However, the interaction between miR-7 and the HPO axis remains unclear. This study aims to determine whether and how miR-7 functions in this axis. A mouse ovariectomy model and mouse primary pituitary cells were used in this study. The Results showed that miR-7 is localized to gonadotrophs and somatotrophs. miR-7 can inhibit the expression, synthesis and secretion of gonadotropins, but not growth hormones. Gonadotropin-releasing hormone(GnRH) has inhibitory effects on miR-7, while estrogen enhances miR-7 expression. miR-7 is vital for the pathway by which GnRH and estrogen regulate gonadotropins by targeting v-raf-leukemia viral oncogene 1(Raf1). Together, these Results indicate that miR-7 acts as a potential switch in the feedback loop of the HPO axis by regulating gonadotropins.

关键词： miR-7 gonadotropins gonadotropin-releasing hormone(GnRH) estrogen hypothalamus-pituitary-ovary(HPO) axis v-raf-leukemia viral oncogene 1(Raf1)

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PROCESS-ORIENTED PRODUCT KNOWLEDGE MANAGEMENT

下丘脑和垂体微小RNAs调控生殖功能的研究进展

2006年中国机械工程学会年会暨中国工程院机械与运载工程学部首届年会

作者： zhang shanhui, LI Zhaoqian, GAO Qi College of Mechanical Engineering, Shandong University, Jinan 250061, China

Along with the application of information technology in themanufacturing industry, enterprise’s business activities andmanagement contained more and more knowledge; theknowledge has become the main me

关键词： Product knowledge management process-oriented knowledge process.

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中华生殖与避孕杂志 2019年第5期39卷 417-421页

作者：贺璟张善辉王平平泰州市第二人民医院检验科 225500

微小RNAs(microRNAs,miRNAs)是一类非编码RNAs,可通过靶标基因发挥多种生物功能。miRNAs调控生殖功能的早期研究集中在性腺水平,近年来的研究也有报道下丘脑和垂体miRNAs也能够调控生殖过程。在下丘脑中,miRNA-9和miRNA-200家族能够调... 详细信息

微小RNAs(microRNAs,miRNAs)是一类非编码RNAs,可通过靶标基因发挥多种生物功能。miRNAs调控生殖功能的早期研究集中在性腺水平,近年来的研究也有报道下丘脑和垂体miRNAs也能够调控生殖过程。在下丘脑中,miRNA-9和miRNA-200家族能够调控促性腺激素释放激素神经元迁移,miRNA-155和miRNA-200家族调控微小青春期,let-7参与青春期启动。在垂体中,miRNA-200b/miRNA-429、miRNA-7a2和miRNA-132/miRNA-212等参与调控垂体促性腺激素分泌,miRNA-27等调控垂体细胞凋亡。这些研究使得miRNAs对生殖的调节从性腺水平提升到下丘脑-垂体-性腺轴的神经内分泌水平。本文就下丘脑和垂体miRNAs在生殖调控中的作用作一综述。

关键词：微小RNAs 下丘脑垂体生殖

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浓硫酸预氧化-浸出工艺处理铋渣

中国有色冶金 2023年第2期52卷 54-59页

作者：赵祝鹏张善辉张腾贺东晓山东恒邦冶炼股份有限公司山东烟台264109

采用火法工艺处理铜、铅阳极泥时,在分银炉氧化精炼过程中会产生氧化渣,即铋渣,其中富含金、银、铜、铋。采用火法工艺处理铋渣,除铜工序采用硫化法或融析脱铜方法,存在生产成本高、能耗高问题,且铜渣会夹带金银,导致金银分散。现有采... 详细信息

采用火法工艺处理铜、铅阳极泥时,在分银炉氧化精炼过程中会产生氧化渣,即铋渣,其中富含金、银、铜、铋。采用火法工艺处理铋渣,除铜工序采用硫化法或融析脱铜方法,存在生产成本高、能耗高问题,且铜渣会夹带金银,导致金银分散。现有采用湿法处理铋渣的工艺均存在含氯废水产生量大的问题,增加了废水处理成本。本文采用浓硫酸实现铋渣中氧化亚铜及单质铜的氧化,然后在稀硫酸的条件下分离铜、铋,浸出液经电积获得黑铜粉,浸出渣经转炉还原熔炼可获得粗铋。条件试验结果表明,在料酸比1:0.65、液固比5:1、反应温度75℃、反应时间1.5 h、搅拌速率250 r/min的条件下,铋渣浸出渣中铜的含量可降至0.1%以下,铋可以富集到46%以上。该方法在不产生含氯废水的条件下实现了铋渣中铜的开路,具有良好的经济与环保效益。

关键词：铜阳极泥铅阳极泥铋渣含氯废水铜铋分离浓硫酸预氧化铋回收铜回收

Na_(2)S-H_(2)O体系浸出高碲砷碱渣中碲的工艺试验研究

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中国有色冶金 2023年第1期52卷 46-53页

作者：张腾张善辉崔家友赵祝鹏山东恒邦冶炼股份有限公司山东烟台264109

山东某有色金属冶炼企业产铅阳极泥,在回收金银时产生的中间物料砷碱渣含碲量高达14%,现有工艺碲回收率低。本文针对在铅阳极泥熔炼生产三氧化二锑过程中产出的高碲砷碱渣开展湿法浸出试验研究,采用Na_(2)S-H_(2)O体系浸出砷碱渣中碲,... 详细信息

山东某有色金属冶炼企业产铅阳极泥,在回收金银时产生的中间物料砷碱渣含碲量高达14%,现有工艺碲回收率低。本文针对在铅阳极泥熔炼生产三氧化二锑过程中产出的高碲砷碱渣开展湿法浸出试验研究,采用Na_(2)S-H_(2)O体系浸出砷碱渣中碲,研究液固比、NaOH浓度、Na_(2)S浓度、浸出时间、浸出温度对碲浸出率影响。研究结果表明,在液固比6∶1、NaOH浓度15 g/L、Na_(2)S浓度40 g/L、浸出时间1 h、浸出温度50℃条件下,碲的浸出率能达到82%。相比传统水浸工艺,该工艺碲浸出率提高了20%。本文可为含碲物料的清洁、高效、短流程分离提取提供理论依据和数据支撑。

关键词：铅阳极泥三氧化二锑碲浸出硫化钠短流程砷碱渣

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高砷铅阳极泥还原熔炼高效脱砷工艺

中国有色冶金 2023年第2期52卷 48-53页

作者：张腾赵祝鹏张善辉杨强陶明光山东恒邦冶炼股份有限公司山东烟台264109

传统铅阳极泥处理工艺为还原熔炼产贵铅-氧化精炼产银阳极板-电解精炼生产银粉,冶炼过程中锑元素基本以Sb_(2)O_(3)形态与As_(2)O_(3)共同进入烟尘中,采用加压浸出工艺处理含砷锑烟尘回收锑。整个工艺流程长、成本高、综合回收率低,而... 详细信息

传统铅阳极泥处理工艺为还原熔炼产贵铅-氧化精炼产银阳极板-电解精炼生产银粉,冶炼过程中锑元素基本以Sb_(2)O_(3)形态与As_(2)O_(3)共同进入烟尘中,采用加压浸出工艺处理含砷锑烟尘回收锑。整个工艺流程长、成本高、综合回收率低,而且废水产生量大,既不经济也不环保。本文利用转炉在高温还原熔炼过程中配入工业氢氧化钠进行高效脱砷处理,砷以砷碱渣形式与贵铅进行分离,生成的贵铅采用真空精馏技术梯级回收有价金属。验证试验结果表明,在加入的氢氧化钠与贵铅合金中砷含量的质量比2:1、反应时间4 h、反应温度1100℃的条件下,砷的脱除率可达95%以上。该工艺与真空精馏技术联合,金、银、铋、锑的回收率均有一定程度提高,而且缩短了流程,减少了锑渣、烟灰、废水等的产生,不但节约了熔炼成本,而且减轻了环保压力,具有良好的示范效应和推广价值。

关键词：铅阳极泥金属回收高效脱砷砷锑烟尘砷碱渣贵铅短流程冶炼节能环保

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聚合物驱采油污水稳定性的影响因素

化工环保 2018年第1期38卷 1-5页

作者：张珊慧刘洋费伯成陈武长江大学化学与环境工程学院湖北荆州434023 石油石化污染物控制与处理国家重点实验室(长江大学) 湖北荆州434023 中国石油抚顺石化公司辽宁抚顺113008

研究了聚合物质量浓度、分子量及原油族组分对模拟含油污水油水界面性质的影响。实验结果表明:聚合物驱采油污水的稳定性不但与聚合物含量、分子量有关,还与原油中沥青质、胶质的含量有关;随着含油污水中阴离子型聚丙烯酰胺(APAM)质量... 详细信息

研究了聚合物质量浓度、分子量及原油族组分对模拟含油污水油水界面性质的影响。实验结果表明:聚合物驱采油污水的稳定性不但与聚合物含量、分子量有关,还与原油中沥青质、胶质的含量有关;随着含油污水中阴离子型聚丙烯酰胺(APAM)质量浓度的增加,油水界面张力逐渐下降,Zeta电位绝对值和油水界面剪切黏度逐渐上升;APAM分子量越小,油水界面张力降低的程度越大;随剪切速率的增加,油水界面剪切黏度均逐渐降低;当剪切速率小于0.30 s^(-1)时,4种原油族组分对污水稳定性影响的大小顺序为沥青质>胶质>芳香分>饱和分;随沥青质、胶质含量的增加,油水界面张力明显降低,Zeta电位的绝对值显著增大。

关键词：聚合物驱含油污水界面张力剪切黏度 Zeta电位