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Ultralow-phase-noise and broadband frequency-hopping coupled optoelectronic oscillator under quiet point operation

Photonics Research 2024年第08期12卷 1785-1793页

作者： HUI LIU MINGYANG GUO TIAN ZHANG JIAN dai kun XU State Key Laboratory of Information Photonics and Optical Communications Beijing University of Posts and Telecommunications School of Electronic Engineering Beijing University of Posts and Telecommunications

Advancements in microwave photonics have yielded novel approaches for generating high-purity microwave sources. Among these, optoelectronic oscillators（OEOs） and coupled optoelectronic oscillators（COEOs） have demonstrated the capability to generate frequency-independent microwaves with exceptionally low phase ***, the tunability of the oscillators is rather limited due to the necessity for narrowband electronic bandpass filters, presenting challenges in achieving both wide and rapid tuning capabilities. Here, we present a COEO featuring ultralow phase noise, flexible tuning capability, and high robustness. This is achieved through a quiet point（QP）-operated harmonic mode-locked fiber laser, which effectively mitigates optical amplifier noise and supermode competition, thus significantly diminishing the necessity for ultra-narrow electronic filters. Due to the liberated tuning ability, we present an oscillator that can be tuned from 2 GHz to 18 GHz, with phase noise as low as-140 d Bc/Hz at 10 k Hz under the QP operation. We then illustrate the practical application of the proposed oscillator in generating frequency-hopping signals with consistent spurious modes less than-85 d Bc,absolute phase noise below-135 d Bc/Hz at 10 k Hz, hopping resolution of 1.25 MHz, and fractional frequency stability below 6.1 × 10-12at 1 s averaging time when locked to a reference. The presented COEO structure emerges as a compelling solution for agile and low-noise microwave sources in advanced wireless communication and radar systems.

关键词： Bandpass filters Beam splitters Microwave photonics Mode-locked fiber lasers Optical amplifiers Phase noise

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In-situ measurement via the flow-through method and numerical simulations for radon exhalation during measurements of the radon exhalation rate

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Nuclear Science and Techniques 2024年第7期35卷 192-207页

作者： Ming Xia Yong-Jun Ye Shan-Wei shang Ting Yu dai-Jia Chen School of Resources Environment and Safety Engineering University of South ChinaHengyang421001China Key Discipline Laboratory for National Defense for Biotechnology in Uranium Mining and Hydrometallurgy University of South ChinaHengyang421001China

Small-scale measurements of the radon exhalation rate using the flow-through and closed-loop methods were conducted on the surface of a uranium tailing pond to better understand the differences between the two *** abnormal radon exhalation behavior was observed,leading to computational fluid dynamics(CFD)-based simulations in which dynamic radon migration in a porous medium and accumulation chamber was *** on the in-situ experimental and numerical simulation results,variations in the radon exhalation rate subject to permeability,flow rate,and insertion depth were quantified and *** in-situ radon exhalation rates measured using the flow-through method were higher than those measured using the closed-loop method,which could be explained by the negative pressure difference between the inside and outside of the chamber during the *** consistency of the variations in the radon exhalation rate between the experiments and simulations suggests the reliability of CFD-based techniques in obtaining the dynamic evolution of transient radon exhalation rates for diffusion and convection at the porous medium-air *** synergistic effects of the three factors(insertion depth,flow rate,and permeability)on the negative pressure difference and measured exhalation rate were quantified,and multivariate regression models were established,with positive correlations in most cases;the exhalation rate decreased with increasing insertion depth at a permeability of 1×10^(−11) m^(2).CFD-based simulations can provide theoretical guidance for improving the flow-through method and thus achieve accurate measurements.

关键词： Radon exhalation Flow-through Numerical simulation Accumulation chamber Multivariate regression

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Insight of enriched basalts into the nature and evolution of mantle lithosphere beneath craton margins

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Science China Earth Sciences 2024年第10期67卷 3128-3142页

作者： Hong-kun dai Jianping ZHENG Qing XIONG Linlin HU Xiang ZHOU State Key Laboratory of Geological Processes and Mineral Resources School of Earth Sciences China University of Geosciences

Refractory lithospheric deep roots are the cornerstone for the prolonged stability of cratons and mantle xenoliths are normally the key targets for study on the evolution of such deep roots. In regions with few mantle xenoliths, the basalts enriched in radiogenic isotopic compositions due to marked lithospheric mantle contribution are crucial to unmask the lithospheric mantle evolution based on a comprehensive study involving petrology, geochemistry and thermodynamic modelling. Here, the Early Cretaceous basalts from the northwest North China Craton with few mantle xenoliths are taken as an example to show the significance of enriched basalts on the study of lithospheric mantle. These basalts are characterized by high silica and alkali contents（SiO2=45.8–59.8 wt.%, K2O+Na2O=4.81–9.88 wt.%）, arc-type trace-element patterns and enriched radiogenic isotope compositions(e.g., εNd=-2.64–-12.88,87Sr/86Sr=0.7063–0.7093). The TiO2and FeO（total） contents are higher than those of natural and experimental melts from refractory mantle peridotite but comparable to those of partial melts of fertile mantle *** high contents of fluid-loving elements（e.g., Rb and Ba） suggest source metasomatism by aqueous fluids. Combined with thermodynamic modelling and regional tectonic history, these enriched basalts likely record simultaneous decompression melting of asthenosphere and low-extent melting of thin and fertile lithospheric mantle fluxed by aqueous fluids from the subducted Paleo-Asian oceanic slab. The newly unmasked lithospheric mantle under the western NCC contrasts with the coeval thick and refractory one supporting the eastern NCC, and highlights that the craton destruction, especially the loss of its ancient refractory mantle root, should take place in a diachronous manner related to the craton-girded subduction episodes. Our study illustrates the potential of enriched basalts to recover the nature and evolution of mantle lithosphere beneath craton margins and associated

关键词： Enriched basalts Lithospheric mantle Northwest North China Craton Tectonic histories Early Cretaceous

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Intrinsically asymmetric atomic character regulates piezoelectricity in two-dimensional materials

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Frontiers of physics 2024年第3期19卷 153-162页

作者： Yun-Qin Li Qi-Wen He dai-Song Tang Xiao shang Xiao-Chun Wang School of Physics Science and Information Technology Liaocheng UniversityLiaocheng 252000China Key Laboratory of Polar Materials and Devices Ministry of EducationDepartment of ElectronicsEast China Normal UniversityShanghai 200241China Institute of Atomic and Molecular Physics Jilin UniversityChangchun 130012China

Decreasing of layer thickness causes the decrease of polarization until it disappears due to the existence of depolarization ***,the search for strong piezoelectric materials is highly desirable for multifunctional ultra-thin piezoelectric ***,we propose a common strategy for achieving strong piezoelectric materials through the electronic asymmetry induced by the intrinsically asymmetric atomic character of different chalcogen ***,in the tetrahedral lattice structures,for example,M4X3Y3(M=Pd/Ni,X/Y=S,Se or Te,X≠Y)monolayers are proved to display excellent out-of-plane ***4Se3Te3 possesses the largest piezoelectric coefficient d33 of 61.57 pm/V,which is much larger than that of most 2D *** the electronic asymmetry further increases the out-of-plane piezoelectricity of Janus M4X3Y3 ***,the out-of-plane piezoelectricity is positively correlated with the ratio of electronegativity difference(Red)and the electric dipole moment(P).This work provides alternative materials for energy harvesting nano-devices or self-energized wearable devices,and supplies a valuable guideline for predicting 2D materials with strong out-of-plane piezoelectricity.

关键词： piezoelectricity intrinsically asymmetric atomic character ratio of electronegativity difference electric dipole moment first-principles calculations

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Antiviral treatment standards for hepatitis B:An urgent need for expansion

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World Journal of Gastroenterology 2024年第4期30卷 418-420页

作者： Zi-Hong Bao Zhi-kun dai Hao-Xian Tang Department of Infectious Diseases The First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Medical College Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Department of Cardiology The First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina

The present letter to the editor is related to the review with the title“Past,present,and future of long-term treatment for hepatitis B virus.”Chronic hepatitis B(CHB)represents an important and pressing public health *** identification and effective antiviral therapy hold the potential to reduce liver-related mortality attributable to chronic infection with hepatitis B virus(HBV)***,the current global treatment rates for CHB remain conspicuously low,with the excessively stringent treatment criteria advocated by national CHB guidelines being a contributing factor to these low ***,recent strides in comprehending this malady and the emergence of novel antiviral agents prompt the imperative re-evaluation of treatment standards to extend the sphere of potential *** impending need arises for a novel paradigm for the classification of patients with CHB,the expansion of antiviral treatment eligibility for HBV-infected individuals,and even the streamlining of the diagnostic process for CHB to amplify cost-effectiveness and augment survival prospects.

关键词： Hepatitis B virus Chronic hepatitis B Antiviral treatment criteria Serum alanine aminotransferase Liver-related mortality Letter to the Editor

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A feature extraction framework for discovering pan-cancer driver genes based on multi-omics data

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Quantitative Biology 2024年第2期12卷 173-181页

作者： Xiaomeng Xue Feng Li Junliang shang Lingyun dai Daohui Ge Qianqian Ren School of Computer Science Qufu Normal UniversityRizhaoChina

The identification of tumor driver genes facilitates accurate cancer diagnosis and treatment,playing a key role in precision oncology,along with gene signaling,regulation,and their interaction with protein *** tackle the challenge of distinguishing driver genes from a large number of genomic data,we construct a feature extraction framework for discovering pan-cancer driver genes based on multi-omics data(mutations,gene expression,copy number variants,and DNA methylation)combined with protein–protein interaction(PPI)*** a network propagation algorithm,we mine functional information among nodes in the PPI network,focusing on genes with weak node information to represent specific cancer *** these functional features,we extract distribution features of pan-cancer data,pan-cancer TOPSIS features of functional features using the ideal solution method,and SetExpan features of pan-cancer data from the gene functional features,a method to rank pan-cancer data based on the average inverse *** features represent the common message of ***,we use the lightGBM classification algorithm for gene *** results show that our method outperforms existing methods in terms of the area under the check precision-recall curve(AUPRC)and demonstrates better performance across different PPI *** indicates our framework’s effectiveness in predicting potential cancer genes,offering valuable insights for the diagnosis and treatment of tumors.

关键词： cancer driver genes feature extraction multi-omics data network propagation pan-cancer

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Bioinspired Hemostatic Strategy via Pulse Ejections for Severe Bleeding Wounds

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Research 2024年第1期2023卷 281-299页

作者： Bitao Lu Enling Hu Weiwei Ding Wenyi Wang Ruiqi Xie kun Yu Fei Lu Guangqian Lan Fangyin dai State Key Laboratory of Silkworm Genome Biology College of SericultureTextile and Biomass SciencesSouthwest UniversityChongqing 400715China Chongqing Engineering Research Center of Biomaterial Fiber and Modern Textile Chongqing 400715China Division of Trauma and Surgical Intensive Care Unit Research Institute of General SurgeryJinling HospitalMedical School of Nanjing UniversityNanjing210002 Jiangsu ProvinceChina Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic UniversityHong KongChina

Efficient hemostasis during emergency trauma with massive bleeding remains a critical challenge in prehospital ***,multiple hemostatic strategies are critical for treating large bleeding *** this study,inspired by bombardier beetles to eject toxic spray for defense,a shape-memory aerogel with an aligned microchannel structure was proposed,employing thrombin-carrying microparticles loaded as a built-in engine to generate pulse ejections for enhanced drug *** aerogels,after contact with blood,can rapidly expand inside the wound,offering robust physical barrier blocking,sealing the bleeding wound,and generating a spontaneous local chemical reaction causing an explosivelike generation of CO_(2) microbubbles,which provide propulsion thrust to accelerate burst ejection from arrays of microchannels for deeper and faster drug *** ejection behavior,drug release kinetics,and permeation capacity were evaluated using a theoretical model and experimentally *** novel aerogel showed remarkable hemostatic performance in severely bleeding wounds in a swine model and demonstrated good degradability and biocompatibility,displaying great potential for clinical application in humans.

关键词： wound sealing offering

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Bichromatically pumped artificial cnoidal wave breathers in optical microresonators

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Photonics Research 2024年第7期12卷 1464-1477页

作者： YIRAN GAO JIAN dai ZHONGHAN WU ANNI LIU TIAN ZHANG WEI SUN JUNQIU LIU kun XU State Key Laboratory of Information Photonics and Optical Communications Beijing University of Posts and TelecommunicationsBeijing 100876China School of Electronic Engineering Beijing University of Posts and TelecommunicationsBeijing 100876China School of Communication Engineering Hangzhou Dianzi UniversityHangzhou 310018China International Quantum Academy Shenzhen 518048China Hefei National Laboratory University of Science and Technology of ChinaHefei 230026China

Breathers are localized structures that undergo a periodic oscillation in their duration and amplitude. Optical microresonators, benefiting from their high-quality factor, provide an ideal test bench for studying breathing phenomena. In a monochromatically pumped microresonator system, intrinsic breathing instabilities are widely observed in the form of temporal dissipative Kerr solitons which only exist in the effectively red-detuned ***, we demonstrate a novel bichromatic pumping scheme to create compulsive breathing microcombs via respectively distributing two pump lasers at the effectively blue-and red-detuned sides of a single *** experimentally discover the artificial cnoidal wave breathers and molecular crystal-like breathers in a photonic chip-based silicon nitride microresonator and theoretically describe their intriguing temporal dynamics based on the bichromatic pumping Lugiato–Lefever equation. In particular, the corresponding breathing microcombs exhibit diverse comb line spacing ranging from 2 to 17 times the free spectral range of the *** discovery not only provides a simple yet robust method to harness microcombs with reconfigurable comb line spacing but also reveals a new class of breathing waves in driven dissipative nonlinear systems.

关键词： pumped resonator pumping

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Mechanisms of tumor immunosuppressive microenvironment formation in esophageal cancer

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World Journal of Gastroenterology 2024年第16期30卷 2195-2208页

作者： Xiao-Jun Zhang Yan Yu He-Ping Zhao Lei Guo kun dai Jing Lv Department of Clinical Laboratory Honghui HospitalXi’an Jiaotong UniversityXi’an 710054Shaanxi ProvinceChina Department of Spinal Surgery Honghui HospitalXi’an Jiaotong UniversityXi’an 710054Shaanxi ProvinceChina Department of Clinical Laboratory Yanliang Railway Hospital of Xi’anXi’an 710089Shaanxi ProvinceChina

As a highly invasive malignancy,esophageal cancer(EC)is a global health issue,and was the eighth most prevalent cancer and the sixth leading cause of cancerrelated death worldwide in *** to its highly immunogenic nature,emerging immunotherapy approaches,such as immune checkpoint blockade,have demonstrated promising efficacy in treating EC;however,certain limitations and challenges still *** addition,tumors may exhibit primary or acquired resistance to immunotherapy in the tumor immune microenvironment(TIME);thus,understanding the TIME is urgent and crucial,especially given the importance of an immunosuppressive microenvironment in tumor *** aim of this review was to better elucidate the mechanisms of the suppressive TIME,including cell infiltration,immune cell subsets,cytokines and signaling pathways in the tumor microenvironment of EC patients,as well as the downregulated expression of major histocompatibility complex molecules in tumor cells,to obtain a better understanding of the differences in EC patient responses to immunotherapeutic strategies and accurately predict the efficacy of ***,personalized treatments could be developed to maximize the advantages of immunotherapy.

关键词： Esophageal cancer Esophageal squamous cell carcinoma Esophageal adenocarcinoma Tumor immune microenvironment Immunosuppression Immunotherapy

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Structural Isomers:Small Change with Big Difference in Anion Storage

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Nano-Micro Letters 2024年第1期16卷 222-234页

作者： Huichao dai Yuan Chen Yueyue Cao Manli Fu Linnan Guan Guoqun Zhang Lei Gong Mi Tang kun Fan Chengliang Wang School of Integrated Circuits Wuhan National Laboratory for Optoelectronics(WNLO)Huazhong University of Science and TechnologyWuhan 430074People’s Republic of China Wenzhou Advanced Manufacturing Institute Huazhong University of Science and TechnologyWenzhou 325035People’s Republic of China Hubei Key Laboratory of Polymer Materials School of Materials Science and EngineeringHubei UniversityWuhan 430062People’s Republic of China School of Chemistry and Environmental Engineering Wuhan Institute of TechnologyWuhan 430073People’s Republic of China

Organic electrode materials are promising for ***,the reported organic electrodes are often facing the challenges of low specific capacity,low voltage,poor rate capability and vague charge storage mechanisms,*** are good platform to investigate the charge storage mechanisms and enhance the performance of batteries,which,however,have not been focused in ***,two isomers are reported for *** a result,the isomer tetrathiafulvalene(TTF)could store two monovalent anions reversibly,deriving an average discharge voltage of 1.05 V and a specific capacity of 220 mAh g−1 at a current density of 2 *** the other hand,the other isomer tetrathianaphthalene could only reversibly store one monovalent anion and upon further oxidation,it would undergo an irreversible solid-state molecular rearrangement to *** molecular rearrangement was confirmed by electrochemical performances,X-ray diffraction patterns,nuclear magnetic resonance spectra,and 1H detected heteronuclear multiple bond correlation *** results suggested the small structural change could lead to a big difference in anion storage,and we hope this work will stimulate more attention to the structural design for boosting the performance of organic batteries.

关键词： Zinc-organic batteries Isomers Solid-state molecular rearrangement Anion storage P-type organic electrode materials

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