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World Journal of Clinical Cases 2025年第4期13卷 41-47页

作者： Xing-Po Li Zi-shan wang Hong-Xia Yu shan-shan wang Department of Cardiovascular Medicine Huantai County Hospital of Traditional Chinese MedicineZibo 256400Shandong ProvinceChina Department of Cardiovascular Medicine Zibo Hospital of Integrated Traditional Chinese and Western MedicineZibo 255500Shandong ProvinceChina

BACKGROUND The incidence of acute myocardial infarction(AMI)is rising,with cardiac rupture accounting for approximately 2%of deaths in patients with acute ST-segment elevation myocardial infarction(STEMI).Ventricular free wall rupture(FWR)occurs in approximately 2%of AMI patients and is notably rare in patients with *** of cardiac rupture include left ventricular FWR,ventricular septal rupture,and papillary muscle *** FWR usually leads to acute cardiac tamponade or electromechanical dissociation,where standard resuscitation efforts may not be *** septal rupture and papillary muscle rupture often result in refractory heart failure,with mortality rates over 50%,even with surgical or percutaneous repair *** SUMMARY We present a rare case of an acute non-STEMI patient who suffered sudden FWR causing cardiac tamponade and loss of consciousness immediate before undergoing coronary *** resuscitation and emergency open-heart repair along with coronary artery bypass grafting resulted in successful patient *** This case emphasizes the risks of AMI complications,shares a successful treatment scenario,and discusses measures to prevent such complications.

关键词： Acute non-ST segment elevation myocardial infarction Cardiac rupture Acute myocardial infarction Free wall rupture Case report

Preparation and desulfurization activity of nano-CeO_2/γ-Al_2O_3 catalysts

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Rare Metals 2018年第7期37卷 554-560页

作者： Qi Yang Hui Hu shan-shan wang School of Environment Science and Engineering Huazhong University of Science and Technology Department of Urban Construction Wuchang Shouyi University Wuhan Zuoling New Town Development and Investment Co. Ltd.

γ-A12O3-supported CeO2 catalysts were pre- pared by microemulsion and impregnation methods and characterized by X-ray diffraction （XRD） and scanning electron microscope （SEM） techniques. At the same time, the desulfurization activity of catalysts was investigated. The results show that nanoscale active substances and a high desulfurization effect are achieved by microemulsion, exhibiting a significant dominance compared with traditional impregnation method. The optimal preparation condition is temperature of 30 ℃ and ratio of [H20]/[surface active agent] of 7 with slow demulsification. The activated catalysts still keep high and stable desulfurization activity during a wide temperature range of 450-600 ℃. Among a series of prepared catalysts, the desulfurization rate of 6CeOz/γ-A1203 is the highest, reaching up to 80 % when temperature is higher than 550℃. The catalytic reduction mechanism of SO2 over nano-CeOz/γ-A1203 follows redox mechanism.

关键词： Nano-CeO2/γ-Al2O3 Microemulsion Catalyst Desulfurization

Empirical Likelihood Inference for a Partially Linear Errors-in-variables Model with Covariate Data Missing at Random

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Acta Mathematicae Applicatae Sinica 2016年第2期32卷 305-318页

作者： shan-shan wang Heng-jian CUI School of Economics and Management Beihang UniversityBeijing 100191China Beijing Key Laboratory of Emergency Support Simulation Technologies for City Operations Beijing 100191China School of Mathematical Sciences&:BCMIIS Capital Normal UniversityBeijing 100048China

The authors study the empirical likelihood method for partially linear errors-in-variables model with covariate data missing at random. Empirical likelihood ratios for the regression coeffidents and the baseline function are investigated, and the corresponding empirical log-likelihood ratios are proved to be asymptotically standard chi-squared, which can be used to construct confidence regions. The finite sample behavior of the proposed methods is evaluated by a simulation study which indicates that the proposed methods are comparable in terms of coverage probabilities and average length of confidence intervals. Finally, the Earthquake Magnitude dataset is used to illustrate our proposed method.

关键词： chi-square distribution confidence region coverage probability empirical likelihood partiallylinear model

The Maximum Surplus before Ruin and Related Problems in a Jump-Diffusion Renewal Risk Process

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Acta Mathematica Sinica,English Series 2011年第12期27卷 2379-2394页

作者： shan shan wang Chun Sheng ZHANG Department of Mathematics Tianjin Polytechnic University Tianjin 300160 P. R. China School of Mathematics and LPMC Nankai University Tianjin 300071 P. R. China

In this paper, we investigate a Sparre Andersen risk model perturbed by diffusion with phase-type inter-claim times. We mainly study the distribution of maximum surplus prior to ruin. A matrix form of integro-differential equation for this quantity is derived, and its solution can be expressed as a linear combination of particular solutions of the corresponding homogeneous integro-differential equations. By using the divided differences technique and nonnegative real part roots of Lundberg＇s equation, the explicit Laplace transforms of particular solutions are obtained. Specially, we can deduce closed-form results as long as the individual claim size is rationally distributed. We also give a concise matrix expression for the expected discounted dividend payments under a barrier dividend strategy. Finally, we give some examples to present our main results.

关键词： Sparre Andersen risk model phase-type inter-claim times maximum surplus before ruin,expected present value of dividends barrier dividend strategy diffusion integro-differential equation

Partial Penalized Empirical Likelihood Ratio Test Under Sparse Case

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Acta Mathematicae Applicatae Sinica 2017年第2期33卷 327-344页

作者： shan-shan wang Heng-jian CUI School of Economics and Management Beihang University School of Mathematical Sciences & BCMIIS Capital Normal University

A consistent test via the partial penalized empirical likelihood approach for the parametric hy- pothesis testing under the sparse case, called the partial penalized empirical likelihood ratio （PPELR） test, is proposed in this paper. Our results are demonstrated for the mean vector in multivariate analysis and regression coefficients in linear models, respectively. And we establish its asymptotic distributions under the null hypoth- esis and the local alternatives of order n-1/2 under regularity conditions. Meanwhile, the oracle property of the partial penalized empirical likelihood estimator also holds. The proposed PPELR test statistic performs as well as the ordinary empirical likelihood ratio test statistic and outperforms the full penalized empirical like- lihood ratio test statistic in term of size and power when the null parameter is zero. Moreover, the proposed method obtains the variable selection as well as the p-values of testing. Numerical simulations and an analysis of Prostate Cancer data confirm our theoretical findings and demonstrate the promising performance of the proposed method in hypothesis testing and variable selection.

关键词： Chi-squared distribution empirical likelihood partial penalized empirical likelihood SCAD sparse

Analysis of vibration and frequency transmission of high speed EMU with flexible model

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Acta Mechanica Sinica 2014年第6期30卷 876-883页

作者： Zun-Song Ren Guang Yang shan-shan wang Shou-Guang Sun School of Mechanical Electronic & Control EngineeringBeijing Jiaotong University

When the operation speed of the high-speed train increases and the weight of the carbody becomes lighter,not only does the sensitivity of the wheel/rail contact get higher,but also the vibration frequency range of the vehicle system gets enlarged and more frequencies are transmitted from the wheelset to the *** is important to investigate the vibration characteristics and the dynamic frequency transmission from the wheel/rail interface to the carbody of the high-speed electric multi-uint（EMU）.An elastic highspeed vehicle dynamics model is established in which the carbody,bogieframes,and wheelsets are all dealt with as flexible body.A rigid high-speed vehicle dynamics model is set up to compare with the simulation results of the elastic *** the rigid vehicle model,the carbody,bogieframes and wheelsets are treated as rigid component while the suspension and structure parameters are the same as used in the elastic *** dynamic characteristic of the elastic high speed vehicle is investigated in time and frequency domains and the di ff erence of the acceleration,frequency distribution and transmission of the two types of models are *** results show that the spectrum power density of the vehicle decreases from the wheelset to the carbody and the acceleration transmission ratio is approximately from 1%to 10%for each suspension *** frequency of the wheelset rotation is evident in the vibration of the flexible model and is transmitted from the wheelset to the bogieframe and to *** results of the flexible model are more reasonable than that of the rigid model.A field test data of the high speed train are presented to verify the simulation *** shows that the simulation results are coincident with the field test data.

关键词： High-speed EMU Vibration transmission Flexible model Acceleration Power spectrum density

Using MALDI-TOF MS coupled with a high-mass detector to directly analyze intact proteins in thyroid tissues

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Science China Chemistry 2018年第7期61卷 871-878页

作者： shan-shan wang Yun-Jun wang Jing Zhang Jun Xiang Tuan-Qi Sun Yin-Long Guo State Key Laboratory of Organometallic Chemistry and National Center for Organic Mass Spectrometry in shanghai Center for Excellence in Molecular Synthesis Shanghai Institute of Organic Chemistry University of Chinese Academy of Sciences Chinese Academy of Sciences Department of Head and Neck Surgery Fudan University Shanghai Cancer Center Department of Oncology Shanghai Medical College Fudan University

Protein analysis is vital for biological and clinical research, but the measurement of unseparated, intact and high-mass proteins is also a challenging task by mass spectrometry-based methods. Here, we present a protocol for rapid and high-throughput analysis of intact proteins in tissue samples using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry（MALDITOF MS） combined with a high-mass detector platform. The method involves tissue specimens that undergo a simple protein extraction before MALDI-MS analysis. Using this method, the high abundance proteins in human thyroid carcinoma and paracarcinoma tissues were successfully investigated, and the mass spectra of the tissues of the 30 illustrated thyroid cancers showed remarkable differences. The peak intensity revealed a significant increase in human albumin in thyroid carcinoma tissues（p＆lt;0.05）. To validate the feasibility and credibility of this method, label-free proteomics quantitative analysis and Western blotting were used to relatively quantify the proteins in these tissues. Those results demonstrated a nearly 3-fold difference in human albumin levels between thyroid carcinoma and para-carcinoma tissues, which were consistent with the results of our method. The advantages of our method are easy sample handling, remarkable reproducibility and the ability to analyze high-mass proteins without digestion, which make them have the potential to be used in biological research and in clinical practice.

关键词： matrix-assisted laser desorption ionization time of flight mass spectrometry intact proteins analysis thyroid carcinoma high-mass detector

Recyclable Carbon Nitride Nanosheet-Photocatalyzed Aminomethylation of Imidazo[1,2-a]pyridines in Green Solvent

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Chinese Journal of Chemistry 2022年第1期40卷 97-103页

作者： Tao Shi Yu-Ting Liu shan-shan wang Qi-Yan Lv Bing Yu School of Biology College of ChemistryZhengzhou UniversityZhengzhouHenan 450001China Institute of Chemistry Henan Academy of SciencesZhengzhouHenan 450002China Beijing Institute of Technology Analysis&Testing Center Beijing Institute of TechnologyBeijing 100081China

An efficient and eco-friendly carbon nitride nanosheet(NM-g-C3N4)-catalyzed decarboxylative coupling reaction of imidazo-fused heterocycles(i.e.,imidazo[1,2-a]pyridines,benzo[d]imidazo[2,1-b]thiazole)with N-phenylglycines in dimethyl carbonate(DMC)has been *** toxic solvents,external oxidants,and restricted reaction conditions could be effectively avoided in this powerful and sustainable ***,NM-g-C3N4 could be straightforwardly recovered by simple centrifugation and recycled and reused at least 7 times without an obvious decrease in catalytic activity.

关键词： Photocatalysis Heterogeneous catalysis Carbon nitride Decarboxylative coupling Green chemistry

Trace determination of hexabromocyclododecane diastereomers in water samples with temperature controlled ionic liquid dispersive liquid phase microextraction

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Chinese Chemical Letters 2011年第1期22卷 97-100页

作者： Ru Song Zhao Xia wang Jin Peng Yuan shan shan wang Chuan Ge Cheng Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of shandong Province Analysis and Test Center Shandong Academy of Sciences Jinan 250014 China

A novel temperature controlled ionic liquid dispersive liquid phase microextracfion （TCIL-DLPME） coupled with rapid resolution liquid chromatography-electrospray tandem mass spectrometry （RRLC-ESI-MS-MS） has been developed for the enrichment and determination of three hexabromocyclododecane diastereomers （HBCDs） in water samples. Green solvent ionic liquid （IL） was used as extraction solvent instead of toxic organic solvents. This technique also avoided the usage of dispersive solvent. Some important parameters that might affect the extraction efficiency were optimized. Under the optimum conditions, good linear relationship, sensitivity and reproducibility were obtained. All the limits of detection for the three diastereomers were 0.1 ng/ mL. The linear range was obtained in the range of 1-100 ng/mL for the total amount of three HBCD diastereomers. It was satisfactory to analyze real environmental water samples with the recoveries ranging from 77.2% to 99.3%. The main advantage of the method is toxic organic solvent-free.

关键词： Hexabromocyclododecane Temperature controlled ionic liquid dispersive liquid phase microextraction Rapid resolution liquidchromatography-electrospray tandem mass spectrometry

Network meta-analysis of combination strategies in metastatic hormone-sensitive prostate cancer

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Asian Journal of Andrology 2024年第4期26卷 402-408页

作者： shan-shan wang Xiao-Jie Bian Jun-Long Wu Bei-He wang Sheng Zhang Ding-Wei Ye Department of Urology Fudan University Shanghai Cancer CenterShanghai 200032China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai 200032China Department of Medical Oncology Fudan University Shanghai Cancer CenterShanghai 200032China.

This study compared different doublet and triplet therapies for efficacy and safety in metastatic hormone-sensitive prostate cancer(mHSPC).PubMed,EMBASE,and the Cochrane Library were comprehensively searched for eligible randomized controlled trials(RCTs)published from inception to October *** included abiraterone,apalutamide,enzalutamide,docetaxel,darolutamide,and androgen deprivation therapy(ADT),either as doublet or triplet *** outcomes examined were overall survival(OS),progression-free survival(PFS),castration-resistant prostate cancer(CRPC)-free survival,time to symptomatic skeletal event(SSE),and *** surface under the cumulative ranking curve(SUCRA)was determined to identify the preferred *** RCTs were *** combination of darolutamide,docetaxel,and ADT had the highest SUCRA of 84.3 for OS,followed by combined abiraterone,docetaxel,and ADT(SUCRA=71.6).The highest SUCRAs for PFS were observed for triplet therapies(abiraterone,docetaxel,and ADT[SUCRA=74.9],followed by enzalutamide,docetaxel,and ADT[SUCRA=74.3])and other androgen receptor axis-targeted therapy-based doublet therapies(SUCRAs:26.5–59.3).Darolutamide,docetaxel,and ADT had the highest SUCRAs,i.e.,80.8 and 84.0 regarding CRPC-free survival and time to SSE,*** Grade>3 adverse events(AEs),the SUCRAs of triplet therapies(SUCRAs:14.8–31.5)were similar to that of docetaxel and ADT(SUCRA=39.5).Three studies had a low risk of bias in all categories;the remaining studies had at least an unclear risk of bias in at least one *** therapy demonstrated potentially enhanced effectiveness than doublet therapy in mHSPC,with acceptable safety *** might be the optimal option for triplet therapy in combination with docetaxel and ADT.

关键词： androgen antagonist androgen receptor antagonist docetaxel meta-analysis prostatic neoplasm