检索结果-南通市图书馆

材料热处理学报 2004年第5期25卷 256-259页

作者： yuanZhi-shan CHENSui-yuan ZHOULi LIUChang-sheng ZHANGJi ZHANGJian-wei SchoolofMaterials＆Metallurgy NortheasternUniversityShenyangChina CentralIronandSteelResearchInstitute BeijingChina

The heat treatment, including two steps, was proposed to obtain Fine Fully Lamellar (FFL) microstructure on TiAl containing minor Ni. The first step was in (a+y) phase region to get Duplex (DP) microstructure, and the second step was in a phase region transforming DP microstructure into FFL microstructure. The effect of heat treatment on microstructures and properties was studied. The results showed that the static recrystallization kinetics in (a+y) phase region took the form of Avrami equitation, and the remnant lamellae in DP microstructure were detrimental to room temperature tensile properties. The FL microstructures were obtained after heat treatment in phase region using DP microstructure, the uniform FFL microstructure was beneficial to comprehensive properties.

关键词：热处理显微结构 TiAl合金拉伸性能

Mixed nanomicelles loaded with thymopeptides-sodium deoxycholate/phospholipid improve drug absorption

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Natural Medicines 2014年第1期12卷 65-70页

作者： JIN Shi-Xiao JIN Shi-Ying LV Qing-yuan FU shan-shan HAN Jin yuan Hai-Long Department of Pharmacy 302 Military Hospital School of pharmaceutics Chengdu University of TCM

AIM: To improve the absorption of thymopeptides(TH) by preparing sodium deoxycholate/phospholipid-mixed nanomicelles(SDC/PL-MMs). METHODS: TH-SDC/PL-MMs were prepared by a film dispersion method, and then evaluated using photon correlation spectroscopy(PCS), zeta potential measurement, as well as their physical stability after storage for several days. Furthermore, in situ intestinal single-pass perfusion experiments and pharmacodynamics in immunodeficient mice were performed to make a comparison with TH powders and the control drug in absorption properties. RESULTS: A narrow size distribution of nanomicelles, with a mean particle size of(149 ± 8.32) nm and a zeta potential of(-31.05 ± 2.52) mV, was obtained. The in situ intestine perfusion experiments demonstrated a significant advantage in absorption characteristics for TH compared to the other formulations, and oral administration of TH-SDC/PL-MMs potentiated an equivalent effect with i.h. TH in pharmacodynamic studies in immunodeficient mice. CONCLUSIONS: TH-SDC/PL-MMs prepared by a film dispersion method are able to improve the absorption of TH. SDC/PL-MMs might be a good approach for the more effective delivery of drugs like TH.

关键词： In situ intestinal absorption Sodium deoxycholate Phospholipid Micelles Thymopeptides Immunodeficiency

Preparation of Poly(ε-caprolactone)/Poly(ester amide)Electrospun Membranes for Vascular Repair

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2022年第4期38卷 1111-1117页

作者： ZHANG Xiangyu BAI shan ZANG Leilei CHEN Xiaoqi yuan Xiaoyan School of Materials Science and Engineering Tianjin Key Laboratory of Composite and Functional MaterialsTianjin UniversityTianjin300350P.R.China Institute of Energy Resources Hebei Academy of SciencesShijiazhuang050081P.R.China

With adjustable amphiphilicity and anionic/cationic charge,biodegradability and biocompatibility,amino acid-based poly(ester amide)s(PEAs)have drawn attention in the research of tissue engineered vascular *** this work,L-phenylalanine-based PEAs with or without L-lysine were synthesized through polycondensation,and ultrafine fibrous grafts consisted of PEAs and poly(ε-caprolactone)(PCL)in given mass ratios were further prepared via blend *** characterizations by Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy confirmed the chemical structure,and the wettability indicated that the prepared PCL/PEAs electrospun membranes exhibited less hydrophobic than *** results showed that the PCL/PEAs membranes possessed suitable mechanical properties,which could meet the requirements of artificial blood *** culture and hemolytic tests exhibited that the PCL/PEAs electrospun membranes are *** general,the electrospun grafts of PCL/PEAs could be applied for vascular repair.

关键词： Poly(ester amide) Poly(ε-caprolactone) Electrospun membrane Mechanical property Vascular repair

Shifts in the bacterial community caused by combined pollutant loads in the North Canal River, China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2023年第5期127卷 541-551页

作者： Shengguang yuan Wenqiang Zhang Wenye Li Zhenhan Li Minshan Wu Baoqing shan State Key Laboratory of Environmental Aquatic Chemistry Research Centre for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China Beijing Forestry University Beijing 100083China Hebei University of Engineering Handan 056038China

A typical anthropogenically disturbed urban river polluted by a combination of conventional pollutants(nitrogen and phosphorus pollution)and heavy metals was investigated along a 238 km *** in the bacterial community were evaluated using high-throughput sequencing,and the relationships between bacteria,heavy metals,and conventional pollutants were *** was large spatial heterogeneity in the bacterial community along the river,and bacterial diversity in the upstream and midstream sections was much higher than in the downstream *** metals and conventional pollutants both exhibited close correlations with bacterial diversity and *** instance,potential fecal indicator bacteria,sewage indicator bacteria and pathogenic bacteria,such as Ruminococcus and Pseudomonas,were closely associated with Cu,Zn,and NH_(4)^(+)-*** than conventional pollutants,heavy metals were the main driving factors of the microbial community *** results confirm that bacterial communities play a crucial role in biogeochemical ***,heavymetals could be used as biomarkers of complex pollution to indicate the pollution status of riverine ecosystems and contribute to the restoration of habitats in anthropogenically disturbed urban rivers.

关键词： Bacterial community Heavy metal Nitrogen pollution Bioindicator

GRB 210323A:Signature of Long-lasting Lifetime of Supra-massive Magnetar as the Central Engine from the Merger of Binary Neutron Star

在线全文

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2024年第8期24卷 32-41页

作者： Yingze shan Xiaoxuan Liu Xing Yang Haoyu yuan Houjun Lü Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China Department of Astronomy School of PhysicsHuazhong University of Science and TechnologyWuhan 430074China

Theoretically,a supra-massive neutron star or magnetar may be formed after the merger of binary neutron ***210323A is a short-duration gamma-ray burst(GRB)with a duration of lasting~1 *** light curve of the prompt emission of GRB 210323A shows a signal-peaked structure and a cutoff power-law model can adequately fit the spectra with E_p=1826±*** interestingly,it has an extremely long-lasting plateau emission in the X-ray afterglow with a duration of~10^(4)s,and then follows a rapid decay with a decay slope~*** temporal feature is challenging by invoking the external shock *** this paper,we suggest that the observed long-lasting X-ray plateau emission is caused by the energy injection of dipole radiation from supra-massive magnetar,and the abrupt decay following the longlasting X-ray plateau emission is explained by supra-massive magnetar collapsing into a black *** is the short GRB(SGRB)with the longest X-ray internal plateau emission powered by a supra-massive neutron *** this is the case,one can estimate the physical parameters of a supra-massive magnetar,and compare with other *** also discuss the possible gravitational-wave emission,which is powered by a supra-massive magnetar and its detectability,and the possible kilonova emission,which is powered by r-process and magnetar spin-down to compare with the observed data.

关键词： (stars)gamma-ray burst general-(stars)gamma-ray burst individual(GRB 210323A)-stars magnetars

Environmental conditions and genetic differentiation:what drives the divergence of coexisting Leymus chinensis ecotypes in a large-scale longitudinal gradient?

在线全文

学校读者我要写书评

暂无评论

Journal of Plant Ecology 2016年第5期9卷 616-628页

作者： shan yuan Chengyuan Guo Linna Ma Renzhong Wang State Key Laboratory of Vegetation and Environmental Change Institute of BotanyChinese Academy of SciencesBeijing 100093China University of Chinese Academy of Sciences Beijing100093 China

Aims The two coexisting Leymus chinensis ecotypes exhibit remarkable divergences in adaptive strategies under drought and salinity in semi-humid meadows and semi-arid *** order to detect the major genetic and environmental factors dominating the intraspecific phenotype variations and ecotype formation,the questions regarding the two distinct phenotypic forms(ecotypes)in ***-ensis were addressed:(i)did environments drive the *** ecotype formation?(ii)was there a molecular basis for the morphological divergence between the two ecotypes?(iii)which driving force dominated the intraspecies divergence,divergent natural selection,genetic drift or stabilizing selection?Methods We applied a series experiments on demographical,morphological and physiological traits of two Leymus chinensis ecotypes with gray green(GG)and yellow green(YG)leaf color in nine wild sites along a longitudinal gradient from 114°to 124°E in northeast *** environmental data including mean annual precipitation,mean annual temperature,elevation and soil properties were *** compared the differences of morphological,physiological and genetic differentiations between the two *** FindingsThe GG type exhibited stronger fitness than YG type from the population densities,morphological traits(*** height,leaf area,leaf and seed weights et al.),leaf mass per area(LMA)and physiological traits[relative water content(RWC),proline,soluble sugar contents].Most of above phenotypes(*** shoot densities,spike length et al.)were significantly correlated with mean annual precipitation,mean annual temperature and soil water content(SWC),rarely a correlated with soil pH and soil *** populations showed convergence trend by their leaf chlorophyll contents and osmotic adjustments(proline and soluble sugar contents)in the greenhouse,but still exhibited their divergences between two ecotypes in the outdoor transplantation,suggesting that whether ***

关键词： genetic differentiation large-scale gradient microsatellites phenotypic traits Leymus chinensis ecotypes

A New Signature Scheme with Shared Verification

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Journal of China Universities of Posts and Telecommunications 2006年第2期13卷 66-69页

作者： JIA Xiao-yun LUO Shou-shan yuan Chao-wei School of Continuing Education Beijing University of Posts and Telecommunications Beijing 100876 P.R. China School of Software Engineering Beijing University of Posts and Telecommunications Beijing 100876 P.R. China National Key Laboratory of Integrated Service Networks Xidian University Xi'an 710071 P.R. China

With expanding user demands, digital signature techniques are also being expanded greatly, from single signature and single verification techniques to techniques supporting multi-users. This paper presents a new digital signature scheme with shared verification based on the fiat-shamir signature scheme. This scheme is suitable not only for digital signatures of one public key, but also for situations where multiple public keys are required. In addition, the scheme can resist all kinds of collusion, making it more practicable and safer. Additionally it is more efficient than other schemes.

关键词： digital signature shared verification verifiable secret sharing

On-chip photonic Fourier transform with surface plasmon polaritons

在线全文

学校读者我要写书评

暂无评论

Light(Science & Applications) 2016年第1期5卷 618-623页

作者： shan shan Kou Guanghui yuan Qian Wang Luping Du Eugeniu Balaur Daohua Zhang Dingyuan Tang Brian Abbey Xiao-Cong yuan Jiao Lin Department of Chemistry and Physics La Trobe Institute for Molecular Science(LIMS)La Trobe UniversityMelbourneVIC 3086Australia Australian Research Council Centre of Excellence for Advanced Molecular Imaging Australia School of Physics The University of MelbourneVIC 3010Australia Centre for Disruptive Photonic Technologies Nanyang Technological UniversitySingapore 637371Singapore Institute of Materials Research and Engineering A*STAR3 Research LinkSingapore 117602Singapore Nanophotonics Research Centre Shenzhen University&Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong ProvinceCollege of Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China School of Electrical and Electronic Engineering Nanyang Technological UniversitySingapore 639798Singapore School of Engineering RMIT UniversityMelbourneVIC 3001Australia

The Fourier transform(FT),a cornerstone of optical processing,enables rapid evaluation of fundamental mathematical operations,such as derivatives and ***,a converging lens performs an optical FT in free space when light passes through *** speed of the transformation is limited by the thickness and the focal length of the *** using the wave nature of surface plasmon polaritons(SPPs),here we demonstrate that the FT can be implemented in a planar configuration with a minimal propagation distance of around 10 mm,resulting in an increase of speed by four to five orders of *** photonic FT was tested by synthesizing intricate SPP waves with their Fourier *** reduced dimensionality in the minuscule device allows the future development of an ultrafast on-chip photonic information processing platform for large-scale optical computing.

关键词： diffraction Fourier optics optical computing optical information processing surface plasmon polaritons

Developments of mucus penetrating nanoparticles

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Pharmaceutical Sciences 2015年第4期10卷 275-282页

作者： Min Liu Jian Zhang Wei shan yuan Huang Key Laboratory of Drug Targeting and Drug Delivery System Ministry of EducationWest China School of PharmacySichuan UniversityNo.17Block 3Southern Renmin RoadChengdu 610041China

Mucus can effectively protect the exposed mucosal surfaces due to its adhesive and viscoelastic *** foreign particulates are efficiently trapped in mucus layers via steric obstruction and *** particles are typically removed from the mucosal tissue within seconds to a few hours depending on their location *** article focuses on describing the tenacious mucus barrier properties,the strategies to investigate the interaction of nanoparticles with the mucus as well as the novel developments of mucus penetrating nanoparticles.

关键词： Mucus barrier Mucus penetrating nanoparticles Mucus properties Experimental strategies

Specific activation of 2'-5'oligoadenylate synthetase gene promoter by hepatitis C virus-core protein:A potential for developing hepatitis C virus targeting gene therapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第25期15卷 3178-3182页

作者： Ying Wang shan-shan Mao Qiong-Qiong He yuan Zi Ji-Fang Wen De-Yun Feng Department of Pathology College of Basic Medical Sciences Central South University Changsha 410078 Hunan Province China Department of Pathology Shanghai Medical College Fudan University Shanghai 200032 China

AIM： TO examine whether 2＇-5＇oligoadenylate synthetase （OAS） gene promoter can be specifically activated by hepatitis C virus （HCV）-core protein. METHODS： Human embryo hepatic cell line L02 was transfected with pcDNA3.1-core plasmid and selected by G418. Expression of HCV-core was detected by reverse transcription polymerase chain reaction and Western blotting. The OAS promoter sequence was amplified from the genomic DNA and inserted into pGL3-basic vector. The resultant pGL3-OAS-Luci plasmid was transiently transfected into L02/core cells and luciferase activity was assayed. I^ESULTS： L02/core cell line stably expressing HCV- core protein was established. The pGL3-OAS-Luci construct exhibited significant transcriptional activity in the L02/core cells but not in the L02 cells. CONCLUSION： HCV-core protein activates the OAS gene promoter specifically and effectively. Utilization of OAS gene promoter would be an ideal strategy for developing HCV-specific gene therapy.

关键词： Hepatitis C virus Gene promoter Gene therapy Core 2'-5'oligoadenylate synthetase