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Cancer Biology & Medicine

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Cancer Biology & Medicine 2019年第1期 205-205页

作者： xi-shan Hao Chinese Academy of Engineering Tianjin Cancer Institute National Clinical Research Center for Cancer

Indexed in PubMed/SCIE IF:4.607Dear colleague,Cancer Biology&Medicine (CBM)(ISSN 2095-3941) is a peer-reviewed open-access journal sponsored by the China Anti-Cancer Association(CACA). Published quarterly, the journal mainly focuses on translational cancer research, dedicating to narrowing the gap between bench and *** adhering to guidelines of the International Committee of Medical

关键词： Cancer Biology Medicine

Cancer Biology & Medicine

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Cancer Biology & Medicine 2018年第3期 186-186页

作者： xi-shan Hao Chinese Academy of Engineering Cancer Biology & Medicine Tianjin Cancer Institute National Clinical Research Center for Cancer

Indexed in PubMed/SCIE IF:4.607 Dear colleague,Cancer Biology&Medicine(CBM)(ISSN 2095-3941)is a peer-reviewed open-access journal sponsored by the China Anti-Cancer Association(CACA).Published quarterly,the journal mainly focuses on translational cancer research,dedicating to narrowing the gap between bench and bedside.

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Totally laparoscopic resection and natural orifice specimen extraction surgery(NOSES)in synchronous rectal and gastric cancer

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Gastroenterology Report 2020年第1期8卷 79-81,I0003页

作者： Yu-Liu-Ming Wang Rui Huang Hong-Yu Wu Han-Qing Hu Ying-Hu Jin Qing-Chao Tang Qiang Li Wei-Yuan Zhang Gui-Yu Wang xi-shan Wang Department of Colorectal Surgery The Second Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiangP.R.China Department of Colorectal Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingP.R.China

Introduction Synchronous gastrointestinal cancer requires simultaneous ***,natural orifice specimen extraction surgery(NOSES)has become a new procedure of minimally invasive surgery[1].Here,we report the first case of NOSES in the treatment of synchronous rectal and gastric *** report The patient was a 68-year-old man with a past medical history of hypertension and coronary heart *** American Society of Anesthesiologists risk score was II and his body mass index was 28.1 kg/m^(2).The endoscopy examination found a 2-cm lesion in the gastric antrum and 3-cm lesion in the middle rectum.

关键词：腹腔镜切除同时性结肠癌 orifice hypertension

Cancer Biology & Medicine

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Cancer Biology & Medicine 2018年第S1期15卷 4-4页

作者： xi-shan Hao Chinese Academy of Engineering Tianjin Cancer Institute National Clinical Research Center for Cance

Indexed in PubMed/SCIE IF:4.607 Dear colleague,Cancer Biology&Medicine(CBM)(ISSN 2095-3941)is a peer-reviewed open-access journal sponsored by the China Anti-Cancer Association(CACA).Published quarterly,the journal mainly focuses on translational cancer research,dedicating to narrowing the gap between bench and bedside.

关键词： Cancer Biology Medicine

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Letter from the Editor-in-Chief

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Cancer Biology & Medicine 2015年第4期12卷 I0002-I0002页

作者： xi-shan Hao Cancer Biology & Medicine Chinese Anti-Cancer Association Union for International Cancer Control

Dearaudience I am very glad to introduce the special issue on ＂lmmunotherapy for lung cancer＂ to youImmunotherapy has recently emerged as a promising therapeutic approach for lung cancer. Clinical trials and research progress on immunotherapy for lung cancer is a spotlight in the Clinical Cancer Advances 2015： Annual Report on Progress Against Cancer From the American Society of Clinical Oncology, attracting attention of re- searchers and clinicians worldwide.

关键词：总编辑临床试验信件免疫治疗年度报告肺癌注意力肿瘤

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CBM is indexed in SCIE

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Cancer Biology & Medicine 2017年第2期 102-102页

作者： xi-shan Hao Chinese Anti-Cancer Association Tianjin Cancer Institute National Clinical Research Center for Cancer Union for International Cancer Control (UICC)

Dear colleague,As the editor-in-chief,I would like to declare the good news that Cancer Biology&Medicine(CBM)has been indexed in Science Citation Index Expanded(SCIE)and will get an impact factor *** the official journal of the Chinese Anti-Cancer Association(CACA)which possesses more than 40,000 members,CBM holds a large audience both in China and *** journal mainly focuses on translational cancer research,dedicating to narrowing

关键词： CBM is indexed in SCIE SCIE

Impact factors of lymph node retrieval on survival in locally advanced rectal cancer with neoadjuvant therapy

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World Journal of Clinical Cases 2020年第24期8卷 6229-6242页

作者： Shi-Wen Mei Zheng Liu Zheng Wang Wei Pei Fang-Ze Wei Jia-Nan Chen Zhi-Jie Wang Hai-Yu Shen Juan Li Fu-Qiang Zhao xi-shan Wang Qian Liu Department of Colorectal Surgery National Cancer Center/National Clinical Research Center for Cancer/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

BACKGROUND Conventional clinical guidelines recommend that at least 12 lymph nodes shouldbe removed during radical rectal cancer surgery to achieve accurate *** application of neoadjuvant therapy has changed the number of lymphnode *** To investigate factors affecting the number of lymph nodes dissected afterneoadjuvant chemoradiotherapy in locally advanced rectal cancer and to evaluatethe relationship of the total number of retrieved lymph nodes(TLN)with diseasefreesurvival(DFS)and overall survival(OS).METHODS A total of 231 patients with locally advanced rectal cancer from 2015 to 2017 wereincluded in this *** to the American Joint Committee on Cancer(AJCC)/Union for International Cancer Control(UICC)tumor-node-metastasis(TNM)classification system and the NCCN guidelines for rectal cancer,thepatients were divided into two groups:group A(TLN≥12,n=177)and group B(TLN<12,n=54).Factors influencing lymph node retrieval were analyzed byunivariate and binary logistic regression *** and OS were evaluated byKaplan-Meier curves and Cox regression *** The median number of lymph nodes dissected was 18(range,12-45)in group A and 8(range,2-11)in group *** lymph node ratio(number of positive lymphnodes/total number of lymph nodes)(P=0.039)and the interval betweenneoadjuvant therapy and radical surgery(P=0.002)were independent factors ofthe ***,TLN was not associated with sex,age,ASA score,clinical T orN stage,pathological T stage,tumor response grade(Dworak),downstaging,pathological complete response,radiotherapy dose,preoperative concurrentchemotherapy regimen,tumor distance from anal verge,multivisceral resection,preoperative carcinoembryonic antigen level,perineural invasion,intravasculartumor embolus or degree of *** pathological T stage(P<0.001)and TLN(P<0.001)were independent factors of DFS,and pathological T stage(P=0.011)and perineural invasion(P=0.002)were independent factors of ***

关键词： Lymph node retrieval Survival analysis Neoadjuvant therapy Rectal cancer Tumor-node-metastasis stage Prognosis

Impact of interval between neoadjuvant chemoradiotherapy and surgery in rectal cancer patients

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World Journal of Gastroenterology 2020年第31期26卷 4624-4638页

作者： Shi-Wen Mei Zheng Liu Fang-Ze Wei Jia-Nan Chen Zhi-Jie Wang Hai-Yu Shen Juan Li Fu-Qiang Zhao Wei Pei Zheng Wang xi-shan Wang Qian Liu Department of Colorectal Surgery National Cancer Center/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

BACKGROUND Epidemiologically,in China,locally advanced rectal cancer is a more common form of rectal *** neoadjuvant concurrent chemoradiotherapy can effectively reduce the size of locally invasive tumors and improve disease-free survival(DFS)and pathologic response after *** present,this modality has become the standard protocol for the treatment of locally advanced rectal cancer in many centers,but the optimal time for surgery after neoadjuvant therapy is still *** To investigate the impact of time interval between neoadjuvant therapy and surgery on DFS and pathologic response in patients with locally advanced rectal *** A total of 231 patients who were classified as having clinical stage II or III advanced rectal cancer and underwent neoadjuvant chemoradiation followed by surgery at the National Cancer Center/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College from November 2014 to August 2017 were involved in this retrospective cohort *** patients were divided into two groups based on the different time intervals between neoadjuvant therapy and surgery:139(60.2%)patients were in group A(≤9 wk),and 92(39.2%)patients were in group B(>9 wk).DFS and pathologic response were analyzed as the primary *** secondary endpoints were postoperative complications and sphincter *** For the 231 patients included,surgery was performed at≤9 wk in 139(60.2%)patients and at>9 wk in 92(39.8%).The patients’clinical characteristics,surgical results,and tumor outcomes were analyzed through univariate analysis combined with multivariate regression *** overall pathologic complete response(pCR)rate was 27.2%(n=25)in the longer time interval group(>9 wk)and 10.8%(n=15)in the shorter time interval group(≤9 wk,P=0.001).The postoperative complications did not differ between the groups(group A,5%vs group B,5.4%;P=0.894).Surgical procedures for sphincter preservation were p

关键词： Interval time Advanced rectal cancer Disease-free survival Pathologic complete response Neoadjuvant therapy Surgery Complication Sphincter preservation

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低能量电子辐照液体甲醇产生负离子团簇

Chinese Journal of Chemical Physics 2024年第1期37卷 24-28,I0117页

作者：陈子伟李子渊田善喜中国科学技术大学化学物理系表界面化学与能源催化安徽省教育厅重点实验室合肥230026 中国科学技术大学合肥微尺度物质科学国家研究中心合肥230026

本文利用线形飞行时间质谱,在低能量电子与液体甲醇碰撞中探测到了负离子产物.利用量子化学计算,进一步确定负离子产物为氢键结合的分子团簇CH_(3)***_(3)O^(-)和CH_(3)***_(3)***_(3)O^(-),而且其单占据分子轨道表现为价层轨道特征.虽... 详细信息

本文利用线形飞行时间质谱,在低能量电子与液体甲醇碰撞中探测到了负离子产物.利用量子化学计算,进一步确定负离子产物为氢键结合的分子团簇CH_(3)***_(3)O^(-)和CH_(3)***_(3)***_(3)O^(-),而且其单占据分子轨道表现为价层轨道特征.虽然CH_(3)***_(3)OH^(-)和CH_(3)***_(3)***_(3)OH^(-)对应各自势能面的极小点,但能量上相比脱氢团簇不具有产生优势,且其单占据分子轨道具有显著的溶剂化电子特征.

关键词：负离子团簇低能量电子液体束

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