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Neural Regeneration Research 2011年第24期6卷 1883-1887页

作者： Jun Chen shan wu Jun Ren Department of Neurology Affiliated Hospital of Guiyang Medical College Guiyang 550004 Guizhou Province China University of Wyoming College of Health Sciences Wyoming INBRE Program Laramie WY 82071 USA

High-resolution ultrasonography was used to analyze the nerve cross-sectional area （CSA） of the median nerve at 7 sites： the wrist crease, pisiform bone, hamate bone, 6 cm proximal to the tip of the wrist crease, proximal forearm （where the nerve enters the pronator teres muscle）, 4 cm proximal to the tip of the medial epicondyle, and mid-humerus （mid-point between elbow crease and axilla） in 200 healthy volunteers from Guiyang, China. Results showed similar CSA values between the left and right sides, but the CSA 6 cm proximal to the tip of the wrist crease, proximal forearm, 4 cm proximal to tip of the medial epicondyle, and mid-humerus in males was greater than that of females. Moreover, CSA values at the wrist crease, pisiform bone, and hamate bone were greater in the middle-aged and old groups when compared to the young group, and correlated with body mass and height. Thus, reference values of median nerve CSA of the upper limbs can facilitate the analysis of abnormal nerve conditions.

关键词： ultrasonography median nerve cross-sectional area Guiyang Han nationality

感恩拓延-建构理论在老年多发性骨髓瘤患者中的应用

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现代科学仪器 2024年第4期41卷 186-189页

作者：王晓婉吴珊马静安徽医科大学附属宿州市立医院血液科安徽宿州234000

目的:探讨感恩拓延-构建理论在老年多发性骨髓瘤患者中的应用效果。方法:随机将纳入研究的80例老年多发性骨髓瘤患者分为观察组和对照组。对照组采用常规健康管理,观察组实施感恩拓延-构建的健康管理。对比两组患者管理前后心理与生活... 详细信息

目的:探讨感恩拓延-构建理论在老年多发性骨髓瘤患者中的应用效果。方法:随机将纳入研究的80例老年多发性骨髓瘤患者分为观察组和对照组。对照组采用常规健康管理,观察组实施感恩拓延-构建的健康管理。对比两组患者管理前后心理与生活质量的变化。结果:观察组感恩和健康知识水平、生活质量测定量表各项评分高于对照组,而汉密顿抑郁量表、汉密顿抑郁量表、恐惧疾病进展简化量表评分低于对照组(P<0.05)。结论:基于感恩拓延-构建理论的健康管理可提高老年多发性骨髓瘤患者感恩和健康知识水平,缓解焦虑、抑郁及对疾病进展的恐惧情绪,改善生活质量。

关键词：老年多发性骨髓瘤管理

Microstructure and mechanical performances of CGHAZ for oil tank steel during high heat input welding

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Rare Metals 2013年第2期32卷 129-133页

作者： Guo-Li Liang shan-wu Yang Hui-Bin wu Xue-Li Liu Department of Material Physics and Chemistry University of Science Technology of BeijingBeijing 100083China National Engineering Research Center for Advanced Rolling Technology University of Science Technology of Beijing Department of Electro-Mechanical Engineering Tangshan College

Microstructure and mechanical performances of the coarse grain heat-affected-zone （CGHAZ） for oil tank steel with different Ti content were investigated through Gleeble-3500, scanning electron microscopy, transmission electron microscopy, and energy dispersive spectrometer. The results show that the strength and low- temperature toughness of base material are significantly improved for the high titanium content steel, but the impact toughness of CGHAZ is seriously deteriorated after the high heat input welding and declined sharply with the heat input increasing, while the effects of heat input on impact toughness are very weak for the low titanium content steel, impact toughness of which is gradually larger than that of high titanium content steel with the welding heat input increasing because of the granular bainite increasing, TiN particle coarsening, and （Ti, Nb） N composition evolution during the high input welding for high titanium content steel.

关键词： Ti-steel CGHAZ Impact toughness TiN particle

侵袭性肺炎克雷伯菌肝脓肿综合征临床及影像学特征

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中国介入影像与治疗学 2024年第2期21卷 84-88页

作者：吴山杨美霞闫俊荣陈吉虎亢志琴山西白求恩医院放射科山西太原030032 山西白求恩医院急诊科山西太原030032

目的观察侵袭性肺炎克雷伯菌肝脓肿综合征(IKPLAS)临床及影像学特征。方法回顾性纳入68例肺炎克雷伯菌肝脓肿(KPLA)患者,根据是否发生肝外侵袭性感染分为IKPLAS组(n=25)及非IKPLAS组(n=43),比较组间临床资料及CT和/或MRI表现。结果IKP... 详细信息

目的观察侵袭性肺炎克雷伯菌肝脓肿综合征(IKPLAS)临床及影像学特征。方法回顾性纳入68例肺炎克雷伯菌肝脓肿(KPLA)患者,根据是否发生肝外侵袭性感染分为IKPLAS组(n=25)及非IKPLAS组(n=43),比较组间临床资料及CT和/或MRI表现。结果IKPLAS组患者年龄低于而糖化血红蛋白、D-二聚体均高于非IKPLAS组(P均<0.05)。IKPLAS组18例、非IKPLAS组6例可见肝静脉血栓性静脉炎,IKPLAS组10例、非IKPLAS组28例可见动脉期脓肿周围异常高灌注,组间差异均有统计学意义(P均<0.05)。IKPLAS组肝外感染主要累及肺(19/25,76.00%)。结论 IKPLAS患者年龄低于而糖化血红蛋白、D-二聚体高于其他KPLA;较常见肝静脉血栓性静脉炎及肝外感染主要累及肺为IKPLAS影像学特征。

关键词：肝脓肿肺炎克雷伯菌体层摄影术 X线计算机磁共振成像

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火热证诊断条目筛选与构建

世界科学技术-中医药现代化 2024年第2期26卷 511-516页

作者：张佳乐吴珊杨燕陈南杰汪锦城胡镜清中国中医科学院中医基础理论研究所北京100700 中国中医药科技发展中心北京100027

目的通过对既往火热证相关诊断规范和火热证临床研究中的四诊信息进行系统分析,总结火热证四诊临床表征,为构建火热证临床诊断标准条目池提供基础。方法检索PubMed、CNKI、WANFANG、CQVIP、CBM等数据库发表的火热证临床研究及相关辨识规... 详细信息

目的通过对既往火热证相关诊断规范和火热证临床研究中的四诊信息进行系统分析,总结火热证四诊临床表征,为构建火热证临床诊断标准条目池提供基础。方法检索PubMed、CNKI、WANFANG、CQVIP、CBM等数据库发表的火热证临床研究及相关辨识规范,描述火热证的症状、舌脉四诊基本信息,并通过名义小组法结合专家咨询法对临床表征进行分析。结果检索火热相关证临床研究文献193条,通过规范化处理后,筛选出63个条目,主要症状为发热、大便秘结、脉数、小便短黄、躁扰不安、舌苔黄、面红、口渴。通过名义小组法,对条目进行优化处理,纳入火热证条目池的11个条目的组成为8个症状、3个舌脉。症状:怕热、面赤、大便秘结、局部红肿热痛(齿龈、咽喉肿痛,口腔溃疡等)、烦躁、口苦、口渴喜冷饮、近期病情波动。舌脉:舌质红、舌苔黄、脉数。结论火热证条目池重点突出“近期病情波动、局部红肿热痛(齿龈、咽喉肿痛,口腔溃疡等)”两个核心症状,在舌脉上以舌质红、舌苔黄、脉数为主,火热证条目池的筛选与构建,可作为未来火热证临床诊断标准研制的依据。

关键词：火热证诊断证候诊断标准条目池

Additive Hazards Regression with Random Effects for Clustered Failure Times

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Acta Mathematica Sinica,English Series 2015年第3期31卷 511-525页

作者： Deng PAN Yan Yan LIU Yuan shan wu Department of Statistics Chinese University of Hong Kong School of Mathematics and Statistics Wuhan University

Additive hazards model with random effects is proposed for modelling the correlated failure time data when focus is on comparing the failure times within clusters and on estimating the correlation between failure times from the same cluster, as well as the marginal regression parameters. Our model features that, when marginalized over the random effect variable, it still enjoys the structure of the additive hazards model. We develop the estimating equations for inferring the regression parameters. The proposed estimators are shown to be consistent and asymptotically normal under appropriate regularity conditions. Furthermore, the estimator of the baseline hazards function is proposed and its asymptotic properties are also established. We propose a class of diagnostic methods to assess the overall fitting adequacy of the additive hazards model with random effects. We conduct simulation studies to evaluate the finite sample behaviors of the proposed estimators in various scenarios. Analysis of the Diabetic Retinopathy Study is provided as an illustration for the proposed method.

关键词： Additive hazards regression clustered failure times counting process empirical process,frailty model checking random effects

Crystal Structure of Macrocalyxin J

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Chinese Journal of Structural Chemistry 2007年第3期26卷 299-302页

作者： HE shan wu Bin SHI Hao SUN Cui-Rong Department of Chemistry. Zhejiang University Hangzhou 310027 China

The title compound, （1α,6β, 11β,14α）-1,7：6,20-diepoxy-6,1 1-dihydroxy- 6,7-secoent- kaur- 16-ene-7,15-dione- 14-acetate （macrocalyxin J）, is a diterpenoid which was isolated from the leaves of Rabdosia macrocalyx and characterized by single-crystal X-ray diffraction. It crystallizes in orthorhombic, space group P212121 with α= 9.3608（8）, b = 14.9787（12）, c = 15.5750（13） A, Z = 4, V = 2183.8（3） A^3, C22H30O9, Mr= 438.46, Dc= 1.334 g/m^3,μ（MoKα） = 0.103 mm^-1, F（000） = 936, the final R = 0.0532 and wR = 0.1262 for 2252 observed reflections （I 〉 2σ（I））. In the molecule, three six-membered rings adopt chair, boat and slightly distorted boat conformations, respectively, while both five-membered rings have approximate envelope conformations.

关键词： crystal structure macrocalyxin J Rabdosia macrocalyx

Update on diffuse large B-cell lymphoma: highlights from the 2022 ASCO Annual Meeting

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Cancer Biology & Medicine 2022年第8期19卷 1117-1120页

作者： Minghan Qiu shan wu Xinrui Chen Huaqing Wang Department of Oncology Tianjin Union Medical CenterNankai UniversityTianjin 300191China The Institute of Translational Medicine Tianjin Union Medical CenterNankai UniversityTianjin 300121China

Diffuse large B-cell lymphoma(DLBCL)is the most common non-Hodgkin’s lymphoma(NHL)and has high *** 30%–50%of patients develop relapsed/refractory(R/R)disease,which remains a major cause of *** recent years,a variety of novel therapies have emerged,including bispecific T-cell engagers(BiTEs),antibody–drug conjugates(ADCs),chimeric antigen receptor T cells(CAR-T),and selective BTK inhibitors,which have provided effective treatment strategies for patients with DLBCL1,***,the 58th Annual Meeting of the American Society of Clinical Oncology(ASCO)was held in Chicago,presenting cutting-edge studies in ***,we discuss a selection of interesting data on this topic.

关键词： lymphoma ASCO mortality

Elastic direct envelope inversion based on wave mode decomposition for multi-parameter reconstruction of strong-scattering media

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Petroleum Science 2022年第5期19卷 2046-2063页

作者： Pan Zhang Ru-shan wu Li-Guo Han Yong Hu College of Geo-exploration Science and Technology Jilin UniversityChangchun 130026JilinChina Modeling and Imaging Laboratory Earth&Planetary ScienceUniversity of California at Santa CruzSanta CruzCalifornia95064USA School of Resources and Geosciences China University of Mining and TechnologyXuzhou 221008JiangsuChina

The parameter reconstruction of strong-scattering media is a challenge for conventional full waveform inversion(FWI).Direct envelope inversion(DEI)is an effective method for large-scale and strongscattering structures imaging without the need of low-frequency seismic ***,the current DEI methods are all based on the acoustic ***,in real cases,seismic records are the combined effects of the subsurface ***,the study of DEI in elastic media is necessary for the accurate inversion of strong-scattering structures,such as salt *** this paper,we propose an elastic direct envelope inversion(EDEI)method based on wave mode *** define the objective function of EDEI using multi-component seismic data and derive its gradient *** reduce the coupling effects of multi-parameters,we introduce the wave mode decomposition method into the gradient calculation of *** update of Vp is primarily the contributions of decomposed *** approaches on Vs gradient calculation are proposed,*** the petrophysical relation and wave mode decomposition ***,we test the proposed method on a layered salt model and the SEG/EAGE salt *** results show that the proposed EDEI method can reconstruct reliable large-scale Vp and Vs models of strong-scattering salt *** successive elastic FWI can obtain high-precision inversion results of the strong-scattering salt *** proposed method also has a good anti-noise performance in the moderate noise level.

关键词： Direct envelope inversion Full waveform inversion Elastic wave Strong-scattering media Multi-parameter

Adaptive Penalized Weighted Least Absolute Deviations Estimation for the Accelerated Failure Time Model

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Acta Mathematica Sinica,English Series 2020年第7期36卷 812-828页

作者： Ming Qiu WANG Yuan shan wu Qing Long YANG School of Statistics Qufu Normal UniversityQufu 273165P.R.China School of Statistics and Mathematics Zhongnan University of Economics and LawWuhan 430073P.R.China

The accelerated failure time model always offers a valuable complement to the traditional Cox proportional hazards model due to its direct and meaningful *** propose a variable selection method in the context of the accelerated failure time model for survival data,which can simultaneously complete variable selection and parameter ***,the proposed method can deal with the potential outliers in survival times as well as heteroscedastic model errors,which are frequently encountered in ***,utilizing the general nonconvex penalty,we propose the adaptive penalized weighted least absolute deviation estimator for the accelerated failure time *** some regularity conditions,we show that the proposed method yields consistent estimator and possesses the oracle *** addition,we propose a new algorithm to compute the estimate in the high dimensional settings,and evaluate the practical utility of the proposed method through extensive simulation studies and two real examples.

关键词： estimation. property. estimator